In this dissertation research project on the topic of 'cannabis only' versus 'polydrug' users, there are three investigations, all of which focus on the occurrence of cannabis-related problems and experiences (PE). These problems and experiences encompass clinical features of cannabis use disorder (CUD) (e.g., cannabis dependence) and problems that might not be caused by any underlying pathological state. The first study aims to estimate the risk of cannabis-related PE, with contrasts between newly incident "cannabis only" users and newly incident cannabis users who use other internationally regulated drugs (IRD) soon after cannabis onset. The second study aims to identify cannabis-IRD latent classes among newly incident cannabis users without prior non-cannabis IRD use and to investigate the extent to which these subgroups might be more or less likely to develop cannabis dependence relatively soon after cannabis onset. The third study investigates covariations of CUD-related PE among newly incident cannabis users, stratified by durations of cannabis use, in which duration is defined as the elapsed time from the month of cannabis onset to the quarter of survey assessment within a 12-month interval.
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