Recombination plays a significant role causing mitochondrial disorders such as cytoplasmic male sterility as well as in the maintenance and expression of plant mitochondrial genomes. Despite this knowledge, the proteins involved and the mechanism by which recombination occurs in plant mitochondria remains uninvestigated. In bacteria the best studied mechanism of homologous recombination requires the RecA protein. These studies addressed whether the E. coli RecA protein could play a role in generating rearrangements that cause mitochondrial disorders.
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