ROTARY PURSUET PERFORMAKCE EN REACTNE AND PROCESS SCHIZGPHRENECS Thesis far the Dear» :35 P21. D. MECHIGAH STAE UNEVERSWY Washer Otis Smifh E959 '{fHEE‘SIS 0.1. This is to certtfg that the thesis entitled ROTARY PURSUIT PERFORMANCE IN REACTIVE AND PROCESS SCHIZOPHRENICS presented by Walter Otis Smith has been accepted towards fulfillment of the requirements for PhoD. degree in P§ychology e” (' Majbz professor {// Date .. "W LIERARY Mk..- nigan Stab Univenity A A ._.-_q.,— ROTARY PURSUIT PERFORMANCE IN REACTIVE AND PROCESS SCHIZOPHRENICS BY Walter Otis Smith AN ABSTRACT Submitted to the School for Advanced Graduate Studies of Michigan State University of Agriculture and Applied Science in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Department of Psychology 1959 Approved %' K? M) Date /; ’/// .51? Walter.O. Smith ABSTRACT The present study was concerned with obtaining an ob- Jective description of the adaptive responses of process and reactive schizophrenics in a motor learning situation. Per- formance on a pursuit rotor task was chosen as a convenient method of accomplishing this purpose. A process schizophrenic is best described as having an early and insidious onset of psychosis with a relative absence of precipitating stress. Typically, he has had an inadequate prepsychotic personality. He shows a tendency to avoid inter- ,personal contacts and presents a clinical picture of flat ‘ affect and a relative absence of confusion. A reactive schizophrenic, on the other hand, is one with as relatively abrupt and stormy onset of psychosis, usually eattributable to a logical and significant stress situation. Inie prepsychotic personality has been normal or neurotic, zuather than schizoid, with perhaps some degree of outgoingness. Tune clinical picture following the psychotic break is likely t4) include severe confusion and many affective components. In the present investigation, Becker's modification of 1319 Elgin Prognostic Scale was utilized for selection of ‘PINDcess and reactive schizophrenics from the schizophrenic POpulation of a Veterans Administration neuropsychiatric hospital. All schizophrenic patients who had been diagnosed 3*! psychotic for less than one year were rated on Becker's Bcéile, and these ratings were found to approximate a normal OUJPve. Subjects in the upper and lower tails of the dis- trdfbution were classified as process and reactive respectively. Walter O. Smith Each of the psychotic classes so selected was divided into four groups with 10 subjects in each group. Pairs of groups (10 subjects from each psychotic class) were then assigned to four conditions of spacing and massing of practice ‘while learning the rotary pursuit task. Massed practice (M) was defined as continuous practice throughout a practice period, and distributed practice (D) was defined as alternat- ing 30 seconds practice and 30 seconds rest. The four con- plications of the process-reactive classificatory concept. If this essentially longitudinal approach is supplemented by an intensified cross-sectional one, perhaps much may be 32 ac c ompli shed . One promising avenue of approach to such a cross- sectional study is through an investigation of the patients' motor performance. The argument that movement factors play a primary role in the adaptation of all forms of animal life to the environment is too convincing to be easily abandoned. Frwn the studies that have been discussed, it seems legitimate to conclude that variations in amount of operant motor behavior are peripheral rather than essential or "core" Variables in at least some cases of schizophrenia. While they give quantitative meaning to the often-expressed ob- servation that schizophrenia is associated with defects of Volition, they add little to our knowledge of the essential characteristics of the disease except in the sense of demon- 8“S-I‘ating that defective conation is a frequent but not in- vamiable concomitant. In a recent study, Reisman (98) found e‘Tidence that differences in motivation and work rate within the schizophrenic group could be predicted from their class- 12E‘lcation as process or reactive. Rather than attempting to establish how much variation a group of patients show in their operant responses, perhaps it would be more fruitful to investigate the factors involved in the variation when it Occurs. Recent advances in the analysis of motor learning Provide objective methods for investigating qualitative clifferences in performance. Applications of such concepts as temporary work decrement, permanent work decrement, and 33 wgrmegp enable us to speak of the ways in which individuals vary in their performance where previously we had been con- fined to measuring the amount of gross variation. The pursuit rotor task has several advantages to recom- mend it in studies of this nature: It requires an activity that is sufficiently different from ordinary life situations to insure that learning it will be largely unaffected by prior experience, yet it is simple enough to be easily under- stood by even relatively confused subjects; and, methods of isolating the pertinent variables have been worked out and experimentally validated by a number of investigators. In addition to this, there is evidence that, given a minimal amount of compliance on the part of the subject, motivational factors play little, if any, part in the appearance of the variables in question (8). Since this evidence was obtained from a sample of college students, however, it may or may not hold true for psychotic patients. It was concluded by Ammons (10), that learning of the movements necessary for performance on the pursuit rotor "may well involve the building up of manual and ocular movement patterns of a bal- listic type". He defined ballistic type movements as "sweep- ing movements where change of direction takes place in less than normal reaction time and is consequently not under dir- ect cortical control". Perhaps related to this factor are the findings of Brewer gt a; (28) that occurrence of brief noises during pursuit rotor performance had "no statistically 34 significant di sinhibition or external inhibition effects..." and that it had no discernable permanent effect on the per- formance level . 35 Preliminary Study A preliminary study to investigate the applicability of the variables involved in the pursuit rotor task to schizo- phrenic patients was carried out. Prior to beginning the study, it was necessary to decide at what speed the rotor should turn. Two considerations were primary in arriving at this decision: (1) A number of studies have shown that schizophrenics as a group tend to be slower than most nor- male on psychomotor tasks, and the degree of their retard- ati on is directly related to the severity of the illness (58, 59, 60, 76, 104, 105, 106); and (2) This investigation was primarily concerned with relationships between variables rather than with measuring amounts of deviations from "nor- mal“ performance. Therefore choosing a rotation speed with- in the capabilities of the particular patient group was of more importance than choosing one giving direct quantitative comParisons to other groups. In pre-experimental trials, it "‘18 empirically determined that patients of the general PSYChotic level of the sample were most often unable to per- form the task at the conventional speed of 60 rpm. Many of the!!! refused to even attempt it. At 45 rpm, however, most or the patients would attempt the task, and could experience some success at it. W2 A Koerth-type pursuit rotor which turned clockwise at 36 45 rpm was employed. The rotor disk was black, 28.5 cm. in diameter, and had a brass target 1.9 cm. in diameter set 8.5 cm. from its center. The styluswas hinged near its wooden handle so additional pressure could not be exerted on the rotor disk by "bearing down" on the stylus. Both the brass target and the rounded tip of the stylus were polished with fine sandpaper before each subject began practice and at each five-minute rest period. Two Standard Electric timers recorded time on target in units of .01 second alternately every 30 seconds. This was readily accomplished by manual operation of a toggle switch, the examiner recording time on target and resetting one time to zero while the other timer was in circuit during massed trials. Distributed trials and the final massed trials were terminated by changing circuits at the same time the examiner said, "stop" in order to pre- vent accidental continuations of time on target. Similarly, the signal to begin was accompanied by a changing of circuits I in order to forestall premature starts upon subjects being told to "get ready". W Each subject was given instructions as to the operation °f the rotary pursuit device and a demonstration in perform- ing the task by the examiner. Following this, the subject was instructed to try it himself. If he demonstrated that he \mderstood what was to be done, trials were begun immed- iately. If he showed himself unable to follow the directions, 37 instructions and demonstration were repeated. Six subjects from the original group of 44 had to be discarded from the sample due to inability or unwillingness to continue. Mass- ed practice (M) consisted of continuous practice while dis- tributed or spaced practice (D) consisted of alternating intervals of 30 seconds work and 30 seconds rest. The first of the three practice sessions consisted of four SO-second distributed trials for all subjects. After a five minute rest, all subjects were given twelve ISO-second trials which were massed for half the subjects and distributed for the other half. Then, after another five-minute rest, these two groups were again divided with half of each group being assigned to massed practice and the other half to distributed practice. Thus there was one group for the first session, two for the second session, and four for the third. The conditions of spacing under which the four subgroups Practiced were: D-D-D; D-D-M; D-M-D; and D-M—M. Each change 01' conditions was accompanied by a five-minute rest, and Prior to each shift in conditions, the subject was informed ‘31. the change. During distributed practice, the subject 8tibod in front of the rotor during the rest interval. He was told "pick up the stylus" five seconds before the be- 81lining ; "get ready" two seconds before the beginning: and "5°" as a signal to start. The subject always began a trial with the rotor in motion. During the longer rest periods, the subject sat down and conversed or read, and similar 38 preparatory instructions were given before the start of a new trial. Results and Discussion Scores for the four groups on Trial 1 were subjected to a sianle analysis of variance as a test that they were random sanqples from the same population prior to differential treat- ment. The differences proved to be statistically nonsignifi- carrt, permitting retention of the null hypothesis. F was equal to .95 with 3 and 36 degrees of freedom. The performance curves for all groups are plotted in Fiégure l. The expected superiority of distributed practice ovwsr massed is immediately observable. Next, straight lines wears fitted to the curves in Figure l by the method of aver- age decrement as suggested by Ammons (6, 7), and the straight 111168 were extrapolated forward and backward to estimate Whiit the scores on adjacent trials would have been had there been no rest. From these data, calculations of warm-up, temporary work decrement, and permanent work decrement were made. “a“ in the figure is the total temporary decrement following distributed conditions and represents 2.87 seconds of time on target. "B" is warm-up decrement under the same conditions, and this represents 2.23 seconds or 78% of the total temporary decrement. If temporary work decrement is corrected for warm-up decrement, only a negligible amount (0.64) remains. This was interpreted as indicating that temporary work decrement (or reactive inhibition) did not 39 HMQRJbra 20 COUZOOMU) 21 20 19 a 1.777.; H .q H H 5 5; m m P‘ N 11 10 1 TRIALS Fig. 1. Performance Curves anfiovariables, Preliminary study. build up under these conditions, and the performance curve of tlie distributed group can therefore be regarded as approx- imating the optimal performance of this sample. “C", repres- entiamg 8.22 seconds, is the amount of temporary decrement, following massed practice, and"9“, representing 4.99 seconds, is iflhe amount of warm-up decrement under the same conditions. Temporary work decrement corrected for warm-up decrement is 3. 23 seconds following massed practice. Finally, "E" is the difference between distributed practice and massed practice which does not dissipate spontaneously over rest and is therefore a measure of permanent work decrement or condition- ed. inhibition. This amounts to 2.12 seconds in the present Gates. ‘The above findings indicate that the variables developed f170m pursuit rotor studies are applicable to the study of schizophrenic patients. They also indicate that distribution 017 practice by 30-Seconds work and BO-seconds rest is ef- ikective in preventing accumulation of temporary work decre- xmant in patients of this level of psychosis. It is to be ‘noted, however, that this group averaged somewhat higher scores at a rotor speed of 45 rpm than normal groups show at 60 rpm. Conclusions as to the relative effects of the various factors are reserved until further comparisons can be made . 41 main Study In the foregoing discussion, it was pointed out that clamssification of schizophrenic patients as Process or Re- actisve provided a meaningful additional description of them. Altkiough most of the earlier investigators conceived of process and reactive schizophrenia as a dichotomy, several recent investigators have advocated the use of a continuum aPExroach. A number of factors, both empirical and theoreti- caJL in nature, make the continuum concept appear more advan- taigeous. In the first place, it fits clinical observations more closely. As was mentioned earlier, differences of Opinion as to whether or not a particular person is schizo- Phurenic are not unknown. Such a person might be regarded as near one of the end points of the schizophrenic distribution. Wisthin the unequivocally schizophrenic group, it is rare to fiJmi a case where the patient's history and symptomatology place him completely within one or the other of the two cate- gories. It follows that the continuum is better suited for experimental purposes than is a dichotomy. Whether the over- lap between the two groups is attributable to the relative crudity of our measuring instruments or to the nature of schizophrenia, it nevertheless is uniformly found. A con- tinuum permits the eXperimental use of many patients who would otherwise fall into an indeterminate "mixed" category. At the same time, it avoids a "forced choice" situation 42 where truly borderline individuals must be placed in one group or the other, thus increasing the chances of obscuring the results. From the standpoint of theory, the continuum idea again seems to be more desirable since it adapts itself well to a greater number of theoretical considerations than would a dichotomous approach. A theoretical explanation of the continuum could be, for example, along the lines of Meyer's (91) concept of psychobiological interaction, or of Bellak's (22) psychogenicity-organicity theory, or a purely psychological one such as Becker's (19). For these reasons, it was decided to use a process-reactive continuum in rating the schizophrenic patients included in this study. The next step, then, was to choose a method of doing to. Becker's (19) revision of the Elgin Prognostic Scale was chosen after consideration of the possible advantages and disadvantages connected with it. Eggposes g§_§hg_lnvestigation The present study was undertaken in an attempt to secure additional evidence concerning the validity and practicality of the concepts of process and reactive schizophrenia: A study of modes of adjusting in a motor learning situation was chosen as a means of obtaining an objective cross- sectional sample of adjusting processes in these psychotic groups. Variables derived from studies of pursuit rotor per- formance by normal subjects offered convenient tools for accomplishing this purpose and were therefore adopted in the 43 present investigation. These variables are: temporary in- hibition (reactive inhibition, temporary work decrement), conditioned inhibition (permanent work decrement), and warm- up or set. The present investigation was designed to make use of the findings by Weaver (117), Reynolds and Adams (99), and Denny 23 g; (35) in their studies of the performance of normal subjects. Methodology The procedures of Denny gt a; (35) were duplicated with the exception that the rotor was turned at 50 rpm in the present study whereas the above authors used a rotation speed of 60 rpm. This reduction in rotor speed was considered advisable because of the inability or unwillingness of many psychotic subjects to perform at the more rapid pace. Apparatus The experiment was conducted in a quiet room, nine by twelve feet in size, on the second floor of the hospital ward. ‘Windows along one wall gave a view of only another building approximately two hundred yards away. Further il- lumination, when needed was furnished by a 150 watt bulb above and slightly to the rear of the subject. The same physical equipment that was used in the preliminary study was utilized in this investigation. Subjects Eighty male patients in a VA neuropsychiatric hospital 44 made up the sample for this study. All the psychotic sample was chosen from patients assigned to the Acute and Intensive Treatment Service of the NP hospital. Three hundred fifty two case histories of schizophrenic patients were examined. From these, a total of 176 were chosen on the basis of their having sufficient material to allow rating on the Elgin Prognostic Scale; no history of brain injury or long periods of unconsciousness; diagnosis of psychosis made within the past year; a history free of repeated hospitalizations over the past 10 or 12 years for neuropsychiatric reasons; and definite evidence of the presence of gross schizophrenic symptoms such as hallucinations, delusions, ideas of reference, and bizarre behavior. As was stated earlier, the device chosen for distin- guishing between process and reactive patients was Becker's modification of the Elgin Prognostic Scale. The Elgin Scale was devised by Wittman (122) and first used by her at the Elgin State Hospital. Becker's revision of it (see appendix) consists of twenty statements. Each statement is subdivided into a number of items describing more specifically the de- gree to which the statement is applicable to the person being rated. Each of the sub items is assigned a numerical value, and the scores of all items are summed to arrive at the per- son's total score. Wittman, on the other hand, had used only end points to rate each statement. Becker's addition of intermediate values was designed to "add to the precision of 45 rating" (19). Disadvantages of the scale include a probab- ility of unequal discriminatory ability among the various items and certain departures from the rules of good scale construction. For example, there are different ranges in sub scale numerical values from item to item. Becker's own observation that the scale is curtailed and not discriminat- ing enough at the "normal" end appears to be valid. The advantages, however, seemed to far outweigh the disadvantages. Wittman's original use of the scale (122) showed a two-rater reliability of .87, and subsequent studies (75, 123) showed it to be highly valid as a prognostic instrument. Becker's modification seemed to offer an even greater degree of exact- ness in rating, and at the same time, to permit a grading along the entire length of the continuum. Therefore it ap- peared more suited to a continuum frame of reference than did Wittman's original scale or the method of selection used by Kantor g§_§;_(67). In a study reported by MbDonough (84), the present writer and MhDonough had a two-rater relia- bility coefficient of .89 in rating subjects by use of this scale. Figure 2 presents the ratings given the 176 patients in the present study on Becker's modification of the Elgin Prognostic Scale from case history material and records of behavior since hospitalization. It is readily observable that the distribution of ratings approximate a normal curve. The reactive sample was taken.from the low-score, good 45 woos-:xxwooooaxxxx \( 7l 75 81‘ E? >e<><><><><><><>o<><¢x 5‘54 ><><><><><><><><><><><><><>o<><><><>o<>< saw >< 16 21 26 20 25 30 OXU'I 00\ as WWW d; .5 WWWMWV t2 ‘83 xx><><><>ooc<><><><>o<><><><><><>oo< Fig, 2. Ratings on Elgin Prognostic Scale assigned to population from which psychotic samples were drawn. 47 prognosis end of the distribution and the process sample from the high-score, poor prognosis end. A brief description of the two groups follows. The process group consisted of 40 patients ranging in age from 19 to 39 years. The mean age was 28.6 years. thirty one of the group were white and nine were Negroes. a Diagnoses included 26 schizophrenic reactions of the un- classified type, nine paranoid type, two catatonic type, two simple type, and one mixed paranoid and catatonic. Jl From the group with the 40 highest scores on the Elgin Scale, qualifying them for inclusion in the process sample, a total of four were not used. Two of these were transferred to another hospital, one was too confused to cooperate, and the other refused to leave his ward. The next four high- scoring patients were substituted in their stead. The reactive patients ranged in age from 24.5 to 44 years and had a mean age of 31.8 years. This group also was composed of nine Negroes and 31 whites. Diagnoses included 29 schizophrenic reactions, unclassified type; 6 paranoid type, 2 schizo-affective type, and 3 catatonic type. Four of the group of 40 scoring lowest on the Elgin Scale were discharged from the hospital between the times of rating and testing, and one refused to continue after com- pleting the first practice session. These five patients were replaced in the sample by the five having the next- lowest ratings. Seven other reactive patients received 48 passes of a few days duration between the times of rating and testing, but returned in time to be included in the sample. The relative fluidity of the reactive patient population imposed difficulties in obtaining the sample. On the other hand, this served as an incidental indication of the validity of the scale as a prognostic instrument. As the patients were tested on the pursuit rotor, they were also rated by the examiner in regard to apparent degree of psychosis at that time. An example of the scale used is included in the appendix. The ratings were accomplished simply by checking the point on a straight line at which the particular patient seemed to fall and they were made on the basis of the patients' behavior during the testing and con- versational offerings during the two five-minute rest periods. It should be emphasized that these ratings were more or less subjective on the part of the examiner, and no attempt was made to probe into the patients' deeper feelings or thought processes. After all patients had been rated, the rating sheets were ranked in order from least to greatest amount of psycho- sis apparent. No attempt at quantification was made. Next, White's Rank Test (40) was applied to determine whether or not patients in one of the schizophrenic categories had ap- peared more disturbed than the other. Results of these cal- culations are given in Table 1. As can be seen, the differ- ence did not approach statistical significance and it would 49 not have done so even if a one-tailed test had been applied. In other words, both groups of patients appeared to the ex- aminer to be about equally disturbed. It should also be noted that some of the patients in this sample were being treated with tranquilizing drugs. Amount and rate of drug dosage were in accordance with the regular hospital treatment program and were prescribed by the ward physicians. A check was made as to whether or not this treatment could be expected to vary with respect to the two schizophrenic groups in this study. Ten subjects each were chosen at random from the two groups, and their medi- cation records were checked for the week preceding testing. Four process patients and three reactives were being given Thorazine. The average daily dosage was 300mg. in each case. One patient in each sample was being given Trilafon with the process patient being given 12 mg. daily and the reactive 8 mg. Six reactives and five process patients were not given medication during the week preceding testing. From this small sample, it would appear that the two groups were not given differential drug treatment. Twelve normal subjects were run at 50 rpm in order to be sure that the reduced rotor speed pg; s2 introduced no new variables. The normal group was composed of hospital employees comparable in age to the psychotic group. All testing on the pursuit rotor was done by the in- vestigator between the hours of 9:00 AM and 4:00 PM. 50 Each of the two main groups (process and reactive) was subdivided into four subgroups making eight in all with 10 subjects in each group. The conditions of spacing under which the four groups from each category practiced were: D-D-M; D-M~M; MrD-M; and M-M-M. For purposes of easy refer- ence, the reactive schizophrenic group will hereafter be referred to as R-D-D, R-D-M, etc. While the process schizo- phrenics will be referred to as P-D-D, etc. Since all groups were massed for their final session, only the first two practice conditions differentiate the groups. Instruc- tions to subjects were identical to those given in the pre- liminary study. The first session in each case consisted of twelve BO-second trials; the second of eighteen BO-second' trials; and the third of six 30-second trials. The third session was massed trials for all subjects. The normal group practiced under conditions of M-D-M for the same time periods as did the psychotic S's. Time on target was recorded every 10 seconds for the first two minutes of sessions 1 and 2, and for all of session 3. Otherwise, it was recorded every 30 seconds, and the method of accomplishing this was the same as that previously used in the preliminary investigation. SubJects in each of the two main categories were roughly matched in assignments to the four practice conditions on the basis of their performance during the first 30 seconds or practice. This was accompliShed by a quick estimation and Without interrupting the practice in any way. The 51 graphs in Figures 5 and 6 and the statistical analysis in Table 2 (see Results section) give evidence that the groups were well matched at the beginning of practice. Scores of time on target of the normal sample were converted into per- centage of time on target in order to facilitate comparisons with other published data. Analysis of variance was used as the statistical tech- A fundamental ‘ ‘W——“* '1” WE:- nique for comparisons whenever appropriate. condition for the validity of this procedure is that the l _L mean squares be independent. This condition is not met in the case of percentages. Calculations of differences between the psychotic groups were therefore made from the raw scores rather than from percentage scores. In each case where analysis of variance was used, a test of homogeneity was first applied as recommended by Edwards (40) to assure that the data were sufficiently homogeneous to make the F test applicable. In cases where analysis of variance indicated that sig- nificant differences existed between the groups, Tukey's Gap Test (40) was applied. This test tells how great a dif- ference has to be in order to be considered statistically significant at a pre-determined level. When mean scores are arranged in order of magnitude, gaps between them can then be easily checked to determine whether or not they are statisti- cally significant. In the present study, statistical signifi- cance was arbitrarily placed at the .05 level unless it is 52 otherwi as indi cat ed . 53 . “it?“ ‘r‘ n? _mfix? . RESULTS The mean scores of time on target of the normal sample are presented in Figures 3 and 4. Inspection of the curves reveals that, although this group started at a higher level and continued to achieve better scores than samples run at 60 rpm, the same variables appear. Massed practice during learning was characterized by rapid growth in skill at first. Then inhibitory factors set in, the curve became negatively accelerated, and then took on a downward trend. After a five-minute rest, significant reminiscence was shown, indic- ating that an appreciable amount of inhibition had dissipated over rest. The post-rest practice periods were marked by an initial spurt of warm-up, and then continued in a pattern characteristic of the conditions of spacing or massing. It can be concluded that the slower rotation speed of 50 rpm does not eliminate any of the usual variables encountered in motor learning situations and does not introduce unusual variables into the situation. TABLE 1 White's Rank Test Applied to Estimated Degree of Psychosis in Process and Reactive Patients Mean Standard 2 P P Group Sum of Ranks Rank Deviation score .10 .05 Process 1765 1620 103.75 1.40 1.65 1.96 Reactive 1475 54 1:1. I I i‘i‘."li. 0 0 o 0 0 0 8 7.. 6 5 2 .1. PERCENT TIME TIARGET Asalguide in considering the results obtained from the psychotic samples, several specific questions were formulated wimarespect'to each dependent variable. These questions are: 1. 2. 7. Do process and reactive schizophrenics differ regard- less of conditions of practice? Do they differ on massed practice when this is the , initial practice condition? a Do they differ on spaced practice when this is the . initial practice condition? L ?o they differ on spaced following spaced practice D-D 7 ?0 they differ on massed following spaced practice D-M ? . ?0 they differ on massed following massed practice M-M ? ?0 they differ on Spaced following massed practice M-D 7 The dependent variables by means of which the two psychotic samples were compared were: scores of time on tar- get, reminiscence, temporary inhibition, conditioned inhibi- tion, amount of warm-up decrement, and length of time taken to warm up or regain set after a rest. Each of these varia- bles was discussed in general terms in a preceding section. Operational definitions of each as they are used in the pre- sent study are given together with the results in each case. Time on target was simply the scores recorded for each subject. Scores for all trials within a designated period were summed for each subject. In this way, cumulative scores for each were obtained for the period being investigated. 57 Mean times on target for all practice sessions of the psychotic samples are presented graphically in Figures 5 and 6. Analysis of variance of time on target scores for the first practice period is presented in Table 2. Since all TABLE 2 Analysis of Variance of Total Time on Target, Last Half of Practice Period 1 Sum of Mean Source of variation squares df Square F P Between conditions 8724.08 1 8724.08 13.10 .01 Between diagnoses 571.27 1 571.27 0.86 NS 0 x D interaction 2733.13 1 2733.13 4.10 .05 Within groups (error £616.52 _7_6__ 666.01 Total 62645.00 79 For df l and 76, F.05 = 3.97 F.01 : 6.98 groups were matched at the beginning of practice, the analy- sis of variance which is presented here was calculated over the second half of the practice period. This approach was chosen since it is the conventional method of bringing out more clearly any differences in scores associated with dif- ferent conditions of practice. It should also be noted that only four groups are involved in this analysis since each psychotic group was divided equally into spaced and massed gro_ips for the first practice session. A graphic presentation of the scores of these four groups is given in Figure 7. 58 59 Fig. 6. Process groups, mean time on target It’ll-Ill H |--‘ H ......... \0 co 3 5 6 7 8 9 10 11 Fig. 7. Mean times on target, first practice period 60 12 The superiority of groups practicing under distributed conditions over groups practicing under massed conditions is clearly evident, and this superiority is significant beyond the .01 level (F = 13.10 with l & 76 df). This phenomenon was one of the first observed to be typical of normal sub- jects in motor learning tasks. It's appearance in the psy- chotic samples is therefore to be expected. Of more importance to the present study is the effect of spacing and massing upon the two psychotic types. There proved to be a significant interaction effect between type of psychosis and condition of practice. The reactives re- sponded quite differently under the two conditions of prac- tice while the process groups showed no statistically sig- nificant difference between conditions. Whereas the RD group scored higher than any of the others, the Rm group's performance fell below that of all the others'. Tukey's gap test for significance of differences between adjacent means (Table 3) indicates that the RD groups' performance was better than the PD group's beyond the .05 level of signifi- cance. The difference between the PM and RM groups was in the opposite direction, but was not statistically different. A striking feature of the data is that, while the PD group surpassed the PM group in performance as would be expected, the difference between the groups did not reach statistical significance in this first practice period. Partial answers to our first three questions are as 61 TABLE 3 fiflflfiJs Gap Test Applied to Differences in Time on Target Last Half of Period 1 Groups Mean time on target Difference RD 73.10 PD 56.56 16.54* a PM 47 . 27 11 . 29 I? RM 41 .02 6. 25 ' A significant gap 2 16.21 . L follows: 1. No significant differences in motor performance ap- peared between the two psychotic types pg; g3 (Between types F = 0.86 with l & 76 df). 2. The psychotic groups did not differ significantly under initial massed practice. 3. Reactives were significantly (.05) superior to process on initial spaced practice. Table 4 presents the analysis of variance of time on target scores for the second practice period. Again analysis was computed on the last half of the practice period in order to test more adequately the relationships involved. The reasoning,here is that after the first few minutes of post- rest practice (about ‘2i- to 3 minutes for normal subjects) differences due to reminiscence and warm-up have been com- pensated for, and relationships then become more stable. In addition to this, the last cross-over of performance curves 62 TABLE 4 Analysis of Variance of Total Time on Target, Last Half of Practice Period 2 Sum of Mean Source of variation squares df square F P Between conditions 35295.66 3 11765.22 5.93 .01 Between psychotic types 0.00 l 0.00 0.00 NS C x T interaction 3891.55 3 1297.18 0.65 NS Within groups (error)l4g922.45 72 1985.03 Total 182109.66 79 arising from changes in conditions had occurred by the mid- point of the practice period (Adams & Reynolds (2), Denny (34), Frisbey (45), and Reynolds & Adams (99) have found that the performance curves of normal subjects practicing under similar conditions come together and merge into a single curve after about six minutes regardless of previous conditions of practice). As can be seen from Table 4, differences arising from conditions of practice were significant beyond the .01 level. Interaction between psychotic categories and conditions of practice were no longer significant, however, and differences arising from process versus reactive schizophrenia pg; g2 were nil. The significant F primarily reflects the fact that the groups under massed practice did not merge with each other in either psychotic sample. The RDM group scored consistently higher than the REM group, while the PDM group 63 scored consistently lower than did PMM. These differences were tested by means of the 1.; test, and the results are given in Tables 5 and 6. Group RDM surpassed group RMM at a level of significance beyond .01. Group PDM fell below group PMM, but not to a statistically significant degree. TABLE 5 P % ‘2 Test of Differences in Time on Target l Between Groups RDM and RMM, 1 Last half of Practice Period 2 RDM , )3 Mean 111.78 90.58 Standard error of difference 3.37 between means 2. 6. 29* (11‘ 18 P .01 For 18 df, P.01 = 2.88 TABLE 6 2 Test of Differences in Mean Time on Target Between Groups PDM and PMM, Last Half of Practice Period 2 PMM PDM Mean 98.89 87.47 Standard error of difference 19.36 between means 3 .59 (if 18 __P NS 64 Another kind of difference is seen in the performance cfi'the two DD groups. Whereas during the first practice period the RDD group had outgained the PDD group by a sig- rniicant (.05) amount, the situation appears to be reversed in.the second period. The performance curve of RDD appears essentially flat while group PDD seems to rise in a relatively straight line. This impression was tested by a method sug- gested by Edwards (39). Gains for each group between the first minute of practice in the second period and the last minute of the same session were computed and the differences in gain subjected to a 3 test. Results, presented in Table 7 demonstrate that, during this practice period, group PDD outgained group RDD by an amount significant beyond the .05 level. TABLE 7 3 Test of Differences in Gains Between Groups RDD and PDD From First to Last Nhnute of Practice Period 2 RDD PDD Mean 12.60 18.14 Standard error of difference 2.32 between means jg 2.39"r df 18 P .05 _ For df 18, 19.05 -_- 2.10 13.01 -_- 2.88 .Answers to our original seven questions which would be made on the basis of the second practice period scores are: 65 l. The two schiZOphrenic groups showed no difference in time on target attributable to the psychotic category 22£.§2 (F = 0.00). 2. They differed to a significant (.05) degree in re- action to DD conditions of practice with process groups out- gaining the reactives. 3. They differed to a significant (.01) degree in res- ponse to DM conditions. Reactives showed an elevation effect when compared to the MM group, and the process subjects Show- ed a disruption of performance. 4. They showed no significant differences in response to MD conditions. Both groups showed something of an elev- ation effect when shifted to D conditions and slightly sur- passed the groups that had been under spaced conditions from the beginning. Time on target during the third, and last practice period when all subjects were under the same conditions of practice was subjected to analysis of variance, and the re- sults are presented in Table 8. As can be seen no signifi- cant differences in time on target persisted at this time. All groups had arrived at a comparable level of performance. Reminiscence, or gain over rest, was operationally de- fined in this study as the difference in time~on-target scores between the last 30 seconds of pre-rest practice and the first 30 seconds of post-rest practice. To obtain reminiscence scores, differences in performance were calculated 66 TABLE 8 Analysis of Variance of Time on Target During Practice Period 3 Sum of Mean Source of variation squares df square F P Between.conditions 162.60 3 54.20 0.05 NS Between diagnoses 1.07 1 1.07 0.00 NS 0 x D interaction 3128.92 3 1042.97 0.93 NS Within groups (error) 81059.25_, 12 1125.82 Total 84351 . 84 79 individually for each subject. Analysis of variance of reminiscence scores over the two five-minute rest periods are given in Tables 9 and 10. As can be seen, the only difference that proved to be statistically significant arose from different conditions of practice during the second practice period. These were in the usual direction with TABLE 9 Analysis of Variance of Reminiscence Over 1st Rest Period Sum of Mean Source of variation squares df square F P Between conditions 46.57 3 15.52 2.06 NS Between diagnoses 0.04 1 0.04 0.01 NS 0 x D interaction 31.25 3 10.42 1.38 NS Within groups (error) 542.11 12 7.53 Total 619.97 79 For df 3 a. 72, s05 : 2.74 am ; 4.08 67 1r”:’:.mtw TABLE 10 Analysis of Variance of Reminiscence Over 2nd Rest Period Sum of Mean Source of variation squares df square F P Between conditions 222.45 3 74.15 6.59 .01 Between diagnoses 6.80 1 6.80 0.60 NS '6 x D interaction 64.95 3 21.65 1.92 NS Within groups (error) 810.08 png_ 11.25 Total . 1104.28 79 For df 3 a 72, F.05 : 2.74 F.01 = 4.08 subjects massed in the second practice period showing more reminiscence than subjects who had been assigned to distrib- uted practice during the preceding period. It is worth noting, however, that the performance curves in Figure 5 depict the RDD group as showing an appreciable amount of gain over the second rest period in comparison With the other groups. Over the first rest period, they showed a negligible amount of gain. This is a bit of evid- ence in support of the interpretation to be developed later that group RDD did not find apaced conditions noxious during the first period, but did react negatively to being continued on spaced conditions. The two psychotic groups did not ap- pear to differ in any other way with respect to reminiscence. .Amount of warm-up decrement was operationally defined as the difference between the first 30-second post-rest trial 68 and the peak score of the post-rest spurt. Warm-up decrement, like reminiscence, was computed separately for each of the 80 subjects. Analysis of variance of warm-up decrement for the two post-rest practice periods are presented in Tables 11 and 12. TABLE 11 Analysis of Variance for Amount of Warm-Up Decrement at the Beginning of Practice Period 2 Sum of Nban Source of variation 'squares df square F P Between conditions 13.09 3 4.36 1.99 NS Between diagnoses 1.28 l 1.28 0.58 NS 0 x D interaction 5.11 3 1.70 0.78 NS Within groups (error) 151.22 _12_ 2.19 Total 177.27 79 For df 3 a 72, F.05 = 2.74 F.01 ; 4.08 TABLE 12 Analysis of variance of warm-Up Decrement at Beginning of Practice Period 3 Sum of Mean Spurce of variation squares df square F P Between conditions - 12.44 3 4.15 2.99 .05 Between diagnoses 0.00 1 0.00 0.00 NS 0 x D interaction 6.61 3 2.20 1.58 NS Within groups (error) _199.25 _72 1.39 Total 119.30 79 For df 3 & 72, F.05 = 2.74 F.01 = 4.08 59 again, the only differences of statistical significance were those brought about by the conditions of practice. The two groups undergoing massed practice for both preceding practice sessions showed more warm-up than did groups with spaced practice experience. Presumably, groups under spaced con- ditions would have had more practice in resum ng the task after a rest, so the observed difference is in the expected direction. This 18 also the usual finding in studies utiliz- ing normal subjects With the exception of the Frisbev study (45) after which the present study is chiefly modeled. No differences in amount of warm-up decrement were found between the two psychotic groups. This finding is worthy of special note since it will be referred to in discussing the length of time taken to warm up by the two psychotic groups. Time.required to warm-up was operationally defined as the number of lO-second units of practice taken to reach the' peak of the post-rest spurt in performance. Scores for each subject were arrived at by counting. Since measurements were not made for periods under 10 seconds, a normal distribu- tion of scores could not be expected. Analysis of variance could not, therefore, be appropriately applied to these data. Instead, a simple sign test recommended by Edwards (40) was utilized. The Z-scores presented in Table 13 are corrected for continuity since it is to be eXpectcd that the underlying variable, (length of time to warm up) was normally distributed. This correction has, in every case, the effect of lowering 70 TABLE 13 Time to Warm Up, Beginning of Second Practice Period Z-Scores for Differences Between Groups PMM PMD PDD PDM RMM RMD RDD PMD 0.00 PDD 1.27 0.32 Pow 2.22** 0.32 -0.32 REM 0.63 0.53 ‘1.58* -0.95 RMD 0.00 0.95 ‘0.32 -O.95 0.00 RDD 2.00** 2.00** 0.32 0.00 0.32 1.58 RDM 5.70*** 2.00** 0.95 0.00 0.95 0.95 0.00 * Significant beyond .10 level. ** Significant beyond .05 level. *** Significant beyond .01 level A minus Z-score indicates that the group in the left hand column took longer to warm-up than the group in the top row with which it is compared. Z score of all PM - all RM 1.79* z score of all PD - all RD 2 0.67 2 score of all P - all R a 1.90* the probability of finding significant differences. Inspec- tion of Table 13 reveals that, when all process patients are compared with all reactive patients, the process group took longer to warm up. This difference is significant beyond the 10 percent level of confidence but does not reach the .05 level. Beyond this, the differences found are not meaningful for this study. The groups which had practiced under massed conditions took longer to warm up or regain set than did the distributed-practice groups. Normal subjects show the same 71 effects from spacing and massing. Temporary inhibition was operationally defined as remin- iscence plus warm-up decrement. This measure was obtained by adding together the scores for each subject. The aim here, of course, is to obtain an estimate of what the gain over rest (assumed to be from dissipation of temporary in- hibition) would have been had there been no need to warm up. Analysis of variance of temporary inhibition dissipated over the two rest periods are given in Tables 14 and 15. Over the first rest period, as can be seen, there was a difference at the .01 level of significance between groups practicing under massed and spaced conditions. This difference is in the'usual direction with massed practice groups showing the :most inhibition dissipated over rest. Differences due to psychotic type or to interaction of psychosis and conditions of practice did not approach significance. TABLE 14 Analysis of Variance of Temporary Inhibition Dissipated Over the First Rest Period Sum of Mean Source of variation squares df square F P Between conditions 117.85 3 39.28 4.43 .01 Between diagnoses 1.29 l 1.29 .15 Ns C x D interaction 15.78 3 5.26 .59 NS Within groups (error) 638.15 _12__ 8.86 Total ' 773.07 JFor df 3 & 72, F.05 = 2.74 F.01 : 4.08 72 TABLE 15 Analysis of variance of Temporary Inhibition Dissipated Over Second Rest Period Sum of Mean Source of variation squares df square F P Between conditions 281.72 3 93.91 7.83 .01 Between types 10.73 1 10.73 0.89 NS C x T interaction 82.57 3 27.52 2.29 NS Within groups (error) 864.24 12 12.00 To tel 1239. 26 79 For df 3 a 72, 3205 ; 2.74 10.01 = 4.08 Over the second rest period, the same results were ob- tained with a single exception. The differences due to interaction barely missed significance at the .05 level. Inspection of Figures 5 and 6 again reveals that the RDD group was the only one apparently deviating from normal ex- Pectancies with respect to gain showed over the second rest Period. This suggests that the interaction effect arose largely from the improved performance of the RDD group. Normally, spaced-practice subjects are expected to show little, if any temporary inhibition. Conditioned inhibition was operationally defined as the difference between spaced-practice subjects and massed-Prac" tice subjects on the first post-rest 30-second trial with I"r""“'1"m~up decrement added to the score in each case. Statisti- Cal analysis in this case consisted of applying the t test 1.3 . o differences between the two groups from each psychotic 73 sanmflxe. That is, group PD was compared to group PM and (group RD was compared to group RM. For the first trial of practice period 2, there were 20 pairs of subjects in each psychotic category. The first trial of period 3 provided a 10 pairs each of reactive and process patients for comparison. The results shown in Tables 16 and 17 demonstrate that a statistically significant amount of conditioned inhibition was found after the first practice session for both groups. 1 t the beginning of the third practice session, however, con- if ’1?» - Ja— ditioned inhibition was not found in either case. TABLE 16 ,3 Test for Conditioned Inhibition Following First Practice Period RD RM PD PM Mean 15.12 10.69 13.11 11.60 Standard error of difference between 1.61 1.51 means 3 2.75 1.00 df 18 18 P .05 NS For 18 df, 2.05 : 2.10 P.01 ; 2.88 74 TABLE 17 3 Test for Conditioned Inhibition Following Second Practice Period RDD RMM PDD PMM r-ioan 18. 22 16. 51 17.11 16. 54 Standand error of i difference between 4.93 1.79 ! means i 3; 0 . 35 0 . 32 7 df 8 8 g p, _ .. For 01f, P.05 - 2.31 P.01 - 3.36 75 DISCUSSION This experiment began in an attempt to gain more infor- nntion about process and reactive schizophrenics. A.study of'modes of adjusting in a motor learning situation was chosen as a means of obtaining an objective cross-sectional sample of their adjusting processes. Variables derived from studies of pursuit rotor performance by normal subjects of- ofered convenient tools for accomplishing this purpose and were therefore adopted in the present investigation. The very fact that the investigation was undertaken implies, of course, that differences between the two psychotic groups were expected, although no specific hypothesis were formulated. Indications that differences do, indeed, exist are given by the learning curves of the psychotic subjects under the various conditions of massing and spacing of Statistical evidence gives considerable assurance As will practice. that these differences did not happen by chance. appear later, there was also a high degree of consistency among the various factors. .A finding of primary importance was that all the psy- <flrotic groups arrived at a comparable level of skill at the task after 18 minutes of practice. This neatly demonstrated that the differences cannot be attributed to a deficit in psycho-motor performance by one of the groups. As well as providing corroborative evidence for the same conclusion 76 added weight and meaningfulness to the results of the present investigation. arrived at by Heisman (98) in his study, this finding gives W Performance of the subjects during the first practice period indicated that the reactive patients were more strong- ly ormore immediately affected by differences in the environ- mental situation. The reactive group under spaced conditions surpassed all other groups at a significant level while the RM group fell below all the others. That the difference arose from immediacy of response on the part of the reactives was indicated by several independent lines of evidence in the later practice periods. First, by the end of the second practice period there were no longer any statistically sig- nificant differences between the PDD and RDD groups or be- tween the PMM and the RMM groups. As a matter of fact, both process groups which were spaced for the second practice period now slightly surpassed both reactive groups under the same conditions. It will be recalled that in the first session, the process groups had been significantly lower and that the PDD group made significantly more gain during practice period 2. Another line of evidence is found in the longer time taken by the process group to warm up or regain their set after a rest. That this was truly a relative slowness in regaining set is indicated by the fact that the total amount of warm-up shown by the process patients did not differ significantly from the amount shown by the 77 reactives. In other words, it appears that the process sub- Jects simply took a little longer to arrive at the same stage reached more quickly by the reactives. Still another bit of evidence is supplied by the lack of difference in reminis- cence over the let rest between the two main psychotic groups. Associated with this, of course, is also the lack of differ- ence in temporary inhibition dissipating over rest between practice periods 1 and 2. This would indicate that the process patients were not experiencing massed conditions as either more or less noxious than the reactives did. Upon further analysis of the data, it begins to appear that there were not only differences in speed of adapting to the task, but also differences in kind. Early indications of this were given by the elation effect shown by reactive patients upon any change of conditions, even to more noxious ones. This suggests an attempt at escape; a pattern of flight from present circumstances into new situations. Add- ed liklihood for this interpretation was provided by comments of RDD patients during their second period of spaced practice that they were “bored", "tired", etc. Their performance bore out their verballzations quite well since this group, superior in performance in session 1 when the task was novel, fell below all the other distributed-practice groups in session 2. Following a second five-minute rest, the subjects were told that the next session would be massed. The RDD group 78 then demonstrated that they were not deficient in either ability or learning. They showed a reminiscence effect that was comparable to that shown by the previously-massed groups, then continued to perform as well as the other seven groups. The same interpretation of a flight reaction could ex- plain the performance of the RDM group. Upon being shifted from D to M conditions for the second session, they showed an elevation effect and surpassed the RMM group by a sig- nificant amount. The probability of an aversive response to the on-going state of affairs is pointed up more forcefully by the fact that, during the first practice session, groups RDD and RDM were statistically indistinguishable. While these shifts were taking place, the RMM group continued to be lower than any other. Following the second five-minutes rest, however, it became evident that massing of practice throughout had not been reacted to by this group as being oppressive. They showed a moderate amount of reminiscence over rest, a moderate amount of reactive in- hibition, and they warmed up quickly in the third practice period. They also performed at a level that was not sig- nificantly different from the other seven groups When all were practicing under the same conditions in practice period 3. At first glance, we seem to be faced here with a per- plexing contradiction. The RDD group, under presumably least noxious conditions, reacted in the second p actice 79 period as though these conditions were oppressive. at the same time, the RMM group reacted as though massed conditions were not oppressive, and there were even indications that these conditions were in some way rewarding. Furthermore, assurance that these two groups were equal in ability is given both by the very early learning trials and by the final practice period scores. Our previously-used interpretation of a flight reaction '5 on the part of reactive schizophrenics explains this seeming N‘s—f, . ’. «.n'n—hn_ paradox. If it is assumed that both groups (RDD and RMM) are impelled toward escape from a distressing life situation, the rest follows logically. It could be predicted that massed conditions, being more demanding, would therefore provide a more nearly complete escape. The massed practice group would then obtain secondary gains from the "noxious" conditions. On the other hand, distributed practice could be expected to offer relief during early learning, but then to provide a less and less satisfactory avenue of escape as skill progressed. Subjects would then be expected to reach satiation more quickly, and performance would fall off. This is, of course, exactly what was found in the two groups' performance. The reactive patients' tendency to quickly become satiated or bored when an activity no longer furnishes diversion, hypothesized above, may also be a partial ex- planation for observation that schizophrenics seem unable to 80 maintain set during a prolonged task (51, 57, 58, 59, 60, 76, 87, 104, 106). At this point, it may be noted that a generalized reac- tion pattern of attempted escape from an oppressive situation could also be used to explain the faster warm-up of reactive patients. They, being in a "high drive", "ready for action" state would be exPected to enter more quickly into any act- ivity that offered itself. This interpretation of the data is consistent with the learning theory principle that, given sufficient drive to elicit an activity, differences in drive or motivation affect amplitude of response but do not affect learning. It will be recalled that the various manipulations of spacing and massing of practice had significant effects upon the per— formance of the subjects. Nevertheless, all groups achieved at the same level during the final three minutes under identi- cal conditions. These findings are in accord with those of Reisman (98) who concluded that "...reactive schizophrenics, unlike process, appear to be avoiding a noxious environment". In a theoretical article published as the present in- vestigation was nearing completion, Mednick (89) also sug- gested "...that acute schizophrenics are organisms in a state of heightened drive". As Mednick also points out, a heightened drive state on the part of "acute" patients is consistent with the physiological findings cited at the 81 fir—r“ - ‘ aw . beginning of the present report (36, 46, 47, 48, 49, 87). Something like a converse situation seems to obtain with respect to the process schizophrenics. They entered into the new situation less quickly, but then improved steadily as long as the conditions were unchanged. With a shift to the less noxious spaced conditions of practice they, like the reactive sample, improved in performance. Unlike the reactives, however, process patients shifted from D to M showed a disruption of performance and process patients con- tinued on D conditions continued to improve in performance. As was mentioned earlier, during the second practice period, the PDD group slightly surpassed the RDD group in performance whereas in the first period, the RDD group had scored higher by a significant amount. Three different interpretations might be given to the behavior of the process groups. First, it might be argued that they simply were at a homeostatic or "low drive" state. Thus they would be responding more or less like normal sub- jects to the stimuli present in their external environment. In this case, no special habit patterns of responding would be involved. Another possibility is that the process schizo- phrenics were responding in the same way as the reactives, but with a lag in the onset of the various reactions.. The third possibility is that a difference in habitual modes of adjusting exists between the two psychotic groups. These possible interpretations will be discussed separately. 82 That the process patients were responding like normals seems to be contraindicated by several factors. First, their mean scores were considerably below those of normal subjects. This argument will become more compelling as it develops that all differences isolated by the present study can be adequately explained through the actions of psychological factors. Secondly, the small difference between scores by the PM and PD group in the first session is not found among normal sub- jects. In the third place, the disruptive effect on group PDM of being shifted to massed conditions is not ordinarily found among normal subjects.. Another factor making homeo- stasis no more probable for the process group than for the reactives is that both groups were controlled for duration of psychosis. Although the process group, by definition, "grew" into their psychosis more slowly than the reactives, no member of either group had been overtly psychotic for more than a year. Subjective evidence in the same direction is provided by the investigator's impression of the process patients as being as acutely psychotic as were the reactives. The second possibility, that there was simply a lag in adaptation by the process group, is not so easily disposed of. It may be that with longer prolongation of practice, the process groups would show the same performance character- istics as those shown more quickly by the reactive sample. Only a very considerable extension of practice could fur- nish conclusive evidence for or against this possibility. 83 The fact remains, however, that no indication of such a shiftvms obtained in the present investigation. Further- more, indications in support of the remaining interpretation did appear in the data. That a difference in habitual modes of adjusting brought about the observed differences in performance seems probable. While the reactive patients seemed quite clearly to be show- ing a response of flight from the existing situation, the process patients' responses were more suggestive of an un- willingness or inability to venture into a new activity. Thus they entered a novel situation more SIOWIy and tentat- ively. With success, they became more and more involved in the task, and showed more of the usual reactions with respect to the experimental variables. This concept also explains the otherwise peculiar response of the PDM group during the second practice session. They had experienced success under spaced conditions and then were shifted to a more difficult condition. Their reac- tion then was one of being thwarted and of drawing back from the situation. Consequently, performance was disrupted. With further practice, they recovered and eventually achieved the same degree of skill as the other psychotic subjects. All four groups of process schizophrenics followed this general pattern of initial slowness of entering. into the task, followed by a gradual increase in commitment as they experienced success and became more secure in the situation. 84 It may be concluded that these process patients had not reached a comfortable homeostatic balance. Rather, their hesitancy about venturing into activity gave evidence of their being anxious and ill-at-ease with their life situa- tions. A major difference between the groups seems to lie in the process patients reluctance to expose themselves to :3”— \n G -‘.’ . g .l f potentially threatening situations, while the reactives showed ea erness to chance their current circumstances. 5 a The present findings with respect to process schizo- in? Tim 1. .fl. phrenics are in agreement with the physiological findings of DeVault (36) in his study of process and reactive patients and Williams' (119) study of "early chronic" schizophrenics. They are also in agreement with some other studies of motor behavior in "chronic" schizophrenia (76, 87), and with Reisman's findings regarding process schizophrenics (98). In the study just cited, Reisman concluded that the response pattern of is process group on a different kind of task was best described as one of habitual withdrawal from psychologically neutral stimuli. This description would seem to fit the present process group fairly well. In the Present case, however, the response seemed to be more one of guardedness and readiness to withdraw rather than immediate and non-selective withdrawal from all stimuli. This dif- ference may well be brought about by differences in duration of the psychosis. Reisman chose subjects whose current hospitalizations were for less than one year. Presumably, 85 previous hospitalizations were more or less ignored. The present study was confined to subjects whose psychoses were less than one year in duration. It seems possible, then, that Reisman's subjects simply showed a further development of habit patterns more or less incipient in the present sample. Our present evidence, then, seems to be most reasonably interpreted by ascribing different habitual modes of adjust- ing to the two psychotic groups. The pattern followed by the reactives was one of unrest in their present circumstances and a readiness to move into new situations. This might be described as a flight or Withdrawal from their internal environments. The process patients, on the other hand, demonstrated hesitancy and slowness in entering into a new situation; a sort of tentative withdrawal from the external environment. Limitationg pf Conclusions The present investigation, being confined to variables in a single motor learning situation, generalizations con- cerning other areas must be held tentatively. It is worth noting, however, that these results are consistent with findings from studies utilizing different tasks (50, 76,98), with some conditioning studies (23, 42, 87, 94, 126) and with physiological evidence (36, 46, 47, 48, 49, 119). The data also provide reasons for believing that the observed differences arose from differing habits of reacting or 86 generalized attitudes rather than from factors specific to motor learning. Conclusions regarding permanent or conditioned inhibition are somewhat open to question. The accepted measure of con- ditioned inhibition is calculation of the difference remain- ing between spaced subjects and massed subjects in the first post-rest trial. The assumption here is that temporary in- hibition does not accumulate during spaced practice, there- fore conditioned inhibition cannot be generated under these conditions. hen, since temporary inhibition in massed sub- jects dissipates during rest, any remaining difference will be due to conditioned inhibition in the massed practice group. Since a demonstrable amount of temporary inhibition did occur in the RD group, the above assumptions were ob- viously not met. Therefore we have no good evidence whether or not conditioned inhibition was generated in the present samples to differing degrees. Nevertheless, it is worth noting that significant amounts of conditioned inhibition were shown after the first practice session by the reactive groups. By the end of the five-minute rest following the second practice session neither group showed a sivnificant amount of conditioned inhibition. Something like this phenomenon was found by Ammons (10) in a study of normals under prolonged practice. After all groups were approaching their ceiling performance, differences tended to disappear. 87 “~ ”a. ‘ 'L._ H 1?, .As was stated, this finding must be viewed with reser- vation with respect to determining whether or not conditioned inhibition was actually present. Despite this reservation, some conclusions can legitimately be drawn from the finding. The outstanding fact is that differences between the D and M crou ps of both psycr otic categories had disappeared after F1 H only 18 minutes of practice. Rot only were there no differ- ' ences during the first post-rest trial of period 3, but also none for the final practice session considered as a unit. ,- ~ L) by This might be interpreted as an indication that already ‘ estaslish ca p0 tterns of eactizg were so firmly intrenched in these psychotic samples that they interfered with "normal" reactions to stimuli. Normally, of course, the DD grOL wp would be eXpected to surpass MK groups due to c:Lditf_oned inhibitknlin the la tter. Perhaps it wou i he more justified to conclude more specifically that, for some reason, DD conditions were reacted to as being as noxious e.s LM condition" Implications Obviccs y, replication of all or part of the present study with predictions that the sane maior phenomena would appear would aid in evaluat:ung the present findings. Al- though these results are in aereement with several differing lines of inves 3 tion, there have been relatively few studies Mp6 rating process and reactive schizophrenics as sudi. Fbr this reason, co We. bilit" of samples is often I- 88 questionable. It is possible to find supportive evidence for almost any proposition among the mass of often-contradictory literature on "schizophrenia" considered as an entity. A considerable extension of the duration of practice would also be of interest as a further check on the con- sistency of the observed trends. Since, in the present study, it was found that selection of subjects was most arduous and time-consuming, it would seem to be in the in- terests of efficiency to make every possible use of subjects once they are identified. The present findines could account for the better prog- nosis for reactive patients without recourse to physiological differences. The fact that reactives respond more quickly to environmental differences would make them more amenable to therapeutic manipulations. This could be expected to be a spiraling thing, so that even small differences in rate of responding would bring about an ever-increasing gap between the two groups analagous to "fast learners" and "slow learners" in ordinary school situations. In addition to rate of responding, the reactives' ap- parently greater drive level and their greater ability to enter into a new situation could be eXpected to lead them to try more varied adjusting techniques. Thus, their prognosis for either spontaneous remission or for therapy would be better if it is assumed that movements towards mental health will be rewarding to them and thus more apt to be retained 89 {56“ ----— fl_‘ ‘mafla—I-n- .“W a; I ' :9 h ~J-H... .-. ‘. or repeated. Even without such an assumption, it could be predicted that the reactive schizophrenics' trial beiavior would most probably lead to some kind of change, and the change would be for the better at least part of the time. Another implication concerning the reactives is that they seem disturbed by something in their own life situations. This at least presents the possibility that identification and amelioration of the disturbing circumstances may relieve their conditions. Another implication is that, since reactives seem to be fleeing a noxious life situation, early discharges and passes to return to the conditions associated with onset of psycho- sis should be avoided. Although, as a group, they recover quite quickly when hospitalized, more time would be needed to change habit patterns and attitudes. Longer hospital- izations for these patients might cut down the "return rate", or re-admissions, considerably. In short, the present results point to the hardly- surprising conclusion that reactive schizophrenics should be more amenable to conventional psychotherapeutic approaches, to environmental manipulations, and to spontaneous remissions. It might be added that tranquilizinc drugs could also be ex- pected to be more efficacious for the reactives by calming and controlling their flight reactions, and enabling them to continue longer at a task. ilmplications with respect to the process group are not 90 so optimistic, but they are by no means totally negative. First, since process schizophrenics seem to be hesitant to initiate new activities, hey could not be expected to show "spontaneous remission" as frequently as the reactives. This is a conclusion made after the fact, incidentally, since this is a well-established finding from other studies (19, 20, 123, 124). However, it does follow from the present data. Of more interest is the implication that process schizophrenics would not be apt to be helped, but perhaps made worse by conventional psychotherapy. This folloWS from the fact that these patients are withdrawing from the external environment. Psychotherapy focused upon the patient's feelings and inner life would most probably tend to ac- centuate this non-adaptive behavior. From the present findings, it would seem that the ther- apy of choice for process patients, whatever the duration of their psychosis, should be in the other direction. That is, envouragement to attend to and to manipulate the environment to an ever-increasing degree. Since they are prone to with- draw from frustration or threat, extreme caution would need to be exercised during the early stages. manipulative tasks should be of a nature to provide many opportunities for success but a minimum amount of threat. Interestingly enough, a few recent papers (74, 94, 115) report some success in Just such a "reconditioning" program for "chronic schizophrenics". 91 ‘Whether or not "shock therapy" could be eXpected to make tkuejprocess patients sufficiently uncomfortable in their sitaurtion to drive them from self preoccupation is a debat- able question. There is some face validity to the proposition. Cki the other hand, it could be held with equal lOgio that, since shock is imposed from without, it would lead to an even more profound distrust and rejection of the environment. .Actuarial evidence is somewhat on the side of negative re- sults for "chronic" patients. Since process patients have 'Uae poorer prognosis, it seems reasonable that a larger pro- portion of patients labeled "chronic" would also be class- ified as "process". An interesting incidental conclusion can be drawn from the performance of the normal group under conditions that were relatively easy for them. The shape of their perfor- mance curve seems to furnish corroborative evidence for one of Hull's (56) postulates that has not been widely tested. Hull postulated that increments in habit strength can be con- sidered as a constant fraction of gain yet to be attained. As the limit to which the skill which can be attained (ceil- ing) is approached, the increments in habit, according to Hull, become progressively smaller. Then, since temporary inhibition generated in a task seems to build up to a maximum and then to remain fairly constant, it would be approximately the same regardless of the stage of learning. Thus it follows that the relative decrement from temporary inhibition 92 5 L' L 1 ' r" W F‘- auld be greater the closer performance is to the ceiling. ince the normal 50 rpm group is considerably closer to the ailing at the end of the first practice period than normals t 60 rpm, it is understandable why the present normal- lSSed learning curve flattens and dips at the end of the irst practice period although this is not the case at 60 rpm. 3 other words, this dip would support Hull's notion that shit is negatively accelerated. 93 SUMMER! The present study was concerned with performance of process and reactive schizophrenics on a rotary pursuit task. A process schizophrenic is best described as having an early and insidious onset of psychosis with a relative ab- sence of precipitating stress. Typically, he has had an in- adequate prepsychotic personality. He shows a tendency to avoid interpersonal contacts and presents a clinical picture of flat affect and a relat ve absence of confusion. A reactive schizophrenic, on the other hand, is one With a relatively abrupt and stormy onset of psychosis, usually attributable to a logical and significant stress situation. The prepsychotic personality has been normal or neurotic, rather than schizoid, with perhaps some degree of outgoing— ness. The clinical picture following the psychotic break is likely to include severe confusion and many affective com- ponents. In the present investigation, Becker's modification of the Elgin Prognostic Scale was chosen as the device for selection of process and reactive subjects from the schizo- phrenic population of a neuropsychiatric hospital. All patients who met the criteria for the sample desired were rated on this scale. Their ratings were found to approximate a normal distribution. Subjects in the lower and upper tails L~-J of the distribution were classified as reactive nod process 94 respectively. The subjects so selected were tested on a pursuit rotor in order to obtain measurements of their adaptive behavior in a motor learning situation. Groups from each psychotic category were assigned to identical conditions of spacing and massing of practice while learning the task. Comparisons a? of the adaptive responses of process and reactive schizo- :‘ 1 phrenics were then made. r I Differences which showed a high degree of consistency F throughout the testing were obtained. Statistical treatment 4" of the data provided considerable assurance that these dif- ferences were not chance occurrences. The chief findings with respect to process schizophrenics were: They took longer to adapt themselves and enter into the task. After a rest, they also took longer to regain their set and warm up in resuming practice. When the e u. d) patients were continued under the same conditions for suc- cessive practice periods, they progressively improved in per- formance. When Shifted from spaced practice conditions to the relatively more demanding massed conditions, however, their performance was markedly disrupted. These results were interpreted as indications that process schizophrenics were hesitant in initiating new act- ivities and prone to withdraw when thwarted. Supportive evidence for this interpretation was cited from studies of "chronic" schizophrenia and from the few reported studies 95 that have made use of the process-reactive concept. Findings regarding reactive schizophrenia were largely in the opposite direction. They entered into the novel situation more quickly and took a shorter time to regain set after a rest. When continued under the relatively undemand- ing spaced conditions of practice, their performance deter- iorated. On the other hand, performance continued to im- prove with successive periods of massed practice. When con- m .‘i‘m: III-"a i, I ditions of spacing and massing were shifted in either dir- 21'.“ 1‘; ection, the reactive patients showed an immediate improvement in performance suggestive of an elation effect. These results were interpreted as evidence that reactive schizophrenics avoided their internal environments by a flight into activity. Then, when increasing skill rendered the task less effective as an escape device, satiation set in quickly. Any change in the task was therefore reacted to positively. Supportive evidence for this interpretation was also cited from the literature. Finally, some of the implications of these findings with respect to therapy and prognosis were pointed out. As an incidental finding, supportive evidence was ob- tained for Hull's postulate that increments in habit strength may be considered as a constant fraction of the amount yet to be attained. 96 ‘0 O 10. ll. l2. 13. BI BLI OGRAPHY Ackerman, NJl. In A. H. Rifkin (Ed.), Schizoghrenia in psyphoanalytic office practice. New York: Grune & Stratton, 1957. Adams, J. & Reynolds, B. Rotary pursuit performance as a function of initial level of ability. Amer. Psycholcmist, 1952, I, 261 (abstract). 1] Adams, J. A. Warm-up decrement in performance on the pursuit rotor. Amer. g. Psychol., 1952, g5, 404-414. 4"” i "..' Alprin, S. Relationship of pursuit rotor performance to self adjustment. Mot. Skills Res. Exch., 1950, g, 16 81: 36-39 0 American Psychiatric Association, The Committee on Nomen- clature and Statistics. Qiagnostic and statistical manual: mental disorders. A.P.A. Mental Hospital Service, Wash., 1955. Ammons, R. B. Acquisition of motor skill: I. Quantitative analysis and theoretical formulation. Psychol. Rev., 1947, 53, 263-281. Ammons, R. B. Acquisition of motor skills: II. Rotary pursuit performance with continuous practice before and after a single rest. ,1. u. Psychol., 1947, 31, 393-411. :' I' rm- “g - Ammons, R. B. Relationship of motivation and method of testing to distribution of practice phenomena in rotary pursuit. (Abstracted in Mot. Skills Res. Exch., 1949,;_, 29.) Ammons, R. B. Acquisition of motor skills: III. Effects of initially distributed practice on rotary pursuit performance. 31. 235p, Psychol., 1950, 40, 777-787. Ammons, R. B. Effect of distribution of practice on rotary pursuit "hits". 9;. 2332. Psychol., 1951, El, 17-22. Ammons, R. B. Effects of pre-practice activities on rc8>tary pursuit performance. g. 259. Psychol., 1951, 5;, 1 7.191. Ammons, R. B., Alprin, 8., & Ammcns, Carol. Rotary pursuit performance as related to sex and age of pre-adult sub- jects. ,1. exp. Psychol., 1955, £2, 127-133. Ammons, R. B., Ammons, Carol 5: Morgan, R. L. Subskills in rotary pursuit as affected by rate and accuracy require- ments and by distribution of practice. ,1. gen. Psychpln 1958, E, 259-279. 97 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 28. BIBLIOGRAPHY (cont.) Angyal, A., & Hoskin, R. Physiologic aspects of schizo- phrenic withdrawal. Arch. Neurol. Psychiat., 1940, fig, 621-626 0 Arieti, 3. Interpretation p§_schizophrenia. New York: Robert Brunner, 1955. Ausubel, D. P. A psychopathological classification of schizophrenia. Psychiat. Quart., 1949, 25, 127-144. Ausubel, D. P. Ego development and the personality dis- orders. New York: Grune & Stratton, 1952. Barch, A. Warm-up in massed and distributed pursuit rotor performance. g. 252, Psychol., 1954. 4 , 357-361. Becker, W. C. The relation of severity of thinking dis- order to the process-reactive concept of schizophrenia. Unpublished doctoral thesis, Stanford Univ., 1955. Becker, W. C. A genetic approach to the interpretation and evaluation of the process-reactive distinction in schizophrenia. J. abnorm. soc. Psychol., 1956, 52, 229-236. Beiéak, L. Dementia praecox. New York: Grune & Stratton, 19 . Bellak, L. A multiple factor psychosomatic theory of schizophrenia. Psychiat. Quart., 1949, 22, 738-755. Bender, Loretta & Schilder, P. Unconditioned and conditioned reactions to pain in schizophrenia. Amer. J. Psychiat., 1930 a 2.2, 365-384 0 Bleuler, E. Dementia praecox, pp the ggoup pg schizo- phrenias. New York: International Univ. Press, 1950. Boisen, A. T. Types of dementia praecox, a study in psychiatric classification. Psychiatry, 1938. L, 233-236. Brackbill, G. A. Studies of brain dysfunction in schizo- phrenia. Psychol. Bull., 1956, 53, 210-226. Brackbill, G. A. & Fine, H. J. Schizophrenia and central nervous system pathology. g, abnorm. soc. Psychol., 1956, 2' 310-3130 Brewer, P., Ammons, R. B. & Ammons, Carol. Influence of brief noise on rotary pursuit performance. Mot. Skills R88. EXCho, 1951, 2, 10-150 98 29. 30. 31. 32. 33. 34c 35. 36. 37. 38. 39. 40. 41. 42. 43. BIBLIOGRAPHY (cont.) Cameron, D. E. Early schizophrenia. Amer. g, Psychiat., 1938, 22. 567-582. Cameron, N. The functional psychoses. In J. McV. Hunt (Ed.), Personalit and the behavior disorders. New York: Ronald Press, 194*. Cattell, R. B. Personality: a systematic theoretical and factual study. New York: McGraw-Hill, 1950. Conwell, H. & Ammons, R. B. Joint effects of cyclical practice and rest in rotary pursuit. g. Psychol., 1951, 2., 137 -146 o Darrah, L. Shall we differentiate between schizophrenia and dementia praecox? g. nerv. ment. Dis., 1940, 2;, 323- 328 c ' Denny, M. R. The shape of the post-rest performance curve for the continuous rotary pursuit task. Met. Skills Res. Exch., 1951, 1, 103-105. Denny, M. R., Frisbey, N., & Weaver, J. Rotary pursuit performance under alternate conditions of distributed and massed practice. J. egg. Psychol., 1955, 42, 48-54. Devault, S. Physiological responsiveness in reactive and process schizophrenia. Unpublished doctoral dissertation, Michigan State Univ., 1955. Dey, M. K. & Ammons, R. B. Stimulation-maturation pre- diction of distribution phenomena in compensatory pursuit. Canad. g. Psychol., 1956, 19, 139-146. Dore', L. R., & Hilgard, E. R. Spaced practice and the maturation hypothesis. J. Psychol., 1937. 5. 425-259. Edwards, A. E. Egpgrimental design in psychological Eg- search. New York: Rinehart, 1950. Edwards, A. E. Statistical methods for the behavioral sciences. New York: Rinehart, 1954. Estes, L. A study of reminiscence following spaced and massed practice on a rotary pursuitmeter. Mot. Skills Res. Exch., 1950, _2_, 17-21. Fischer, R. Schizophrenia: a regressive process of adaptation. J. nerv. ment. Dis., 1954, 112, 492-497. French, T. M. 8: Kasanin, J. A psychodynamic study of the recovery ogltwg schizophrenic cases. Psychoanalytic ’ Quart., 19 __J . 99 45. 46. 47. 49. 50. 51. 52. 53. 54. 55. 56. 57. BIBLIOGRAPHY (cont.) Freyhan, F. A. Cause and outcome of schizophrenia. Amer. g. Psychiat., 1955. 112, 161-167. Frisbey, N. Pursuit rotor performance under alternate conditions of distributed and massed practice. Unpublished masters thesis, Michigan State Univ., 1952. Funkenstein, D., Greenblatt, M. & Solomon, H. Autonomic nervous system changes following electric shock treatment. g, nerv. ment. Dis., 1948, 108, 409-422. Funkenstein, D., Greenblatt, M. & Solomon, H. Psycho- physiologica1.study of mentally ill patients: Part I. Amer. g. Psychiat., 1949, 106, 16-28. Funkenstein, D., Greenblatt, M. & Solomon, H. An auto- nomic nervous system test of prognostic significance in relation to electroshock treatment. Psychosom. Mpg., 1952, Lil: 347-3620 Geocaris, K. & Kociker, J. Blood pressure responses of chronic schizophrenic patients to epenephrine and mecholyl. Amer. g. Psychiat., 1956, 112, 808-813. Harvard Medical School. Studies ip behavior therapy: status reports 1;, III & IE. Metropolitan State Hospital, Waltham, Mass., 195375 . Heath, R. G. (chairman) Studies ip_schizophrenia. by the Tulane Department of Psychiatry and Neurology. Cambridge, Harvard Univ. Press, 1954. Hirschstein, R. The significance of characteristic auto- nomic nervous system responses in the adjustment, change. and outcome in schizophrenia. J. nerv. ment. Dis., 1955, 123, 254-262. Hoch, T. A..Acute psychosis with symptoms resembling dementia praecox. Amer. g. Psychiat., 1921, 18, 364-572. Hoskins, R. G. The biology p; schizophrenia. New York, Norton, 1946. Hovland, C. Human learning and retention. In S. Stevens (Ed.), Handbook pf e erimental psychology. New York: John.Wiley, 1951, 613- 9. .Hull, C. S. Principles pf behavior. New York: D. Appleton- Century, 1943. . JHunt, J. McV. & Cofer, C. Psychological deficit. In J. McV. Hunt (Ed.), Personalit and the behavior disorders. Vol. II. .New York: Ronald PFess, I944. 100 W?"‘ :.. ~ BIBLIOGRAPHY (cont.) 58. launch, P. E. Eye-hand coordination in schizophrenic patients and normals as measured by the pursuit meter. Psychol. Bull., 1932, 22, 662. 59. Huston, P. E., Shakow, D. & Riggs, L. A. Studies of motor function in schizophrenia: II reaction time. Q. gen. Psychol., 1937, 16, 39-82. 60. Huston, P. E. & Shakow, D. Learning in schizophrenia. I. pursuit learning. g. Pers., 1948, 11, 52-74. 61. Irion, A. The relation of "set" to retention. Psychol. 1331., 1948, 53, 336-341. 62. Irion, A. Retention as a function of amount of pre-recall warming up. Amer. Psypholo ist, 1949, 4, 219-220 (abstract). 63. Irion, A. Retention and warming-up affects in paired- associate learning. g, exp. Psychol., 1949, 24, 669-675. 64. Jahnke, J. Retention in motor learning as a function of amount of practice and rest. g. exp. Psychol., 1958, 55, 270-273 0 65. Jung, C. G. The psychology of dementia praecox. Nerv. ment. Dis. Monogr., 1944. 66. Kant, 0. Problem of psychogenic precipitation in schizo- phrenia. Psychiat. Quart., 1942, ;§, 341-350. 67. Kantor, R., Wallner, J. & Winder, C. Process and reactive schizophrenia. g. consult. Psychol., 1953. 11, 157-162. 68. Kimble, G. & Horenstein, Betty. Reminiscence in motor learning as a function of length of interpolated rest. lg. pgp. Psychol., 1948, 28, 239-244. 69. Kimble, G. An experimental test of a two-factor theory of inhibition. g. pgp. Psychol., 1949, 32, 15-39. 70. Kimble, G. Performance and reminiscence in motor learning as a function of the degree of distribution of practice. ‘1. pgp. Psychol., 1949, 22, 500-510. 71. Kimble, G. Evidence for the role of motivation in deter- mining the amount of reminiscence in pursuit rotor learning. g. pgp. Psychol., 1951, fig, 248-253. 72. Kimble, G. & Shatel, R. The relationship between two Ikinds of inhibition and the amount of practice. g. pgp. Psychol., 1952, 44, 355-359. 101 73. 74. 75. 76. 77. 78. 79. 80. 81. 82. 83. 84. BIBLIOGRAPHY (cont.) King, G., Merrell, D., Lovinger, E. & Denny, M. Operant motor behavior in acute Sohizophrenics. g. Pers., 1957. gi’ 317-3260 King, G. & Armitage, S. An operant-interpersonal thera- peutic approach to schizophrenia of extreme pathology. Report presented at 1958 A.P.A. meetings. ' King, G. Differential autonomic responsiveness in the process-reactive classification of schizophrenia. g. , gppppp. soc. Ppyphp;., in press. (abstracted by J. ; McDonough 5 . A King, H. Payphomotor aspects p£_menta1 disease: gp’egperi- mental study. Harvard Univ. Press, 1954. a. ‘1 ‘n - Knehr, C. Schizophrenic reaction time responses to var- iable preparatory intervals. Amer. g. Psychiat., 1954, 110, 585-588. 53'7“" Lane, J. E. The effect of a stressful situation on the psychomotor learning of schizophrenic and normal subjects. In Abstracts p; dissertations...Clark Univ. Clark Univ. Bull., 1951, 22, (2035, 146-147. Langfeldt, G. Prognosis in schizophrenia and the factors influencing the course of the disease. Acta Psyphiatrica g Neurologia Supplementum, 1937. $3, 218*“(abstracted from Devault). Langfeldt, G. The diagnosis of schizophrenia. Amer. g. Psychiat., 1951, 108, 123-125. Lewis, N. D. C. Research ip_dementia praecox. The National Comm. for Mental Hygiene. New York, 193 . cited in Arieti, S. (Interpretation pg schizophrenia). Lindquist, E. F. Statistical analysis in educational research. Boston, Houghton-Mifflin, 1945. Lindquist, E. F. Goodness of fit of trend curves and significance of trend differences. gpychometricka, 1947, _l__2_, 65-750 McDonough, J. Perceptual indices of organicity as related to process and reactive schizophrenia. Unpublished doctoral dissertation. Michigan State Univ., 1958. McGeoch, J. A. The psychology 9: human learning. 2nd Ed. revised by A. L. Irion. New York: Longmans-Green, 1952. 102 BIBLIOGRAPHY (cont.) 86. Malamud, W. & Render, N. Course and prognosis in schizo- phrenia. Amer. J. Psychiat., 1935, 55, 1039-1057. 87. Malmo, R., Shagass, C. & Smith, A. Responsiveness in chronic schizophrenia. J. Pers., 1951, 55, 359-375. 88. May, P. Pupillary abnormalities in schizophrenia and during muscular effort. J. ment. Sci., 1948, 54, 89-98. 89. Mednick, S. A. A learning theory approach to research in schizophrenia. Psych. Bull., 1958, 55, 316-325. 90. Helton, A. The effect of rest pauses on the acquisition of the pursuitmeter habit. Psychol. Bull., 1941, 55, 719 (abstract). 91. Meyer, A. Constructive formulation of schizophrenia. Amer. 1);. PS3! Chiato , 1921, 1.8-, 355-364. 92. Noyes, A. P. Modggn Clinical Psychiatry. (4th ed.) Phila. W. B. Saunders, 1956. 93. Peters, H. & Murphree, 0. The conditioned reflex in the chronic schizophrenic. J. clin. pgp. Psychppathology, 1954, 15, 346-347 (author's abstract). 94. Peters, H. & Jenkins, R. L. Improvement of chronic schizophrenic patients with guided problem-solving, moti- vated by hunger. Psychiat. Quart., 1954, 55, 84-101. 95. Pfaffmann, C. & Schlosberg, H. The conditioned knee Jerk in psychotic and normal individuals. J. Psychol., 1936, ;, 201-2060 96. Pincus, G. & Hoagland, H. Adrenal cortical responses to stress in normal men and in those with personality dis- orders. Amer. J. Psychiat., 1949/50, 106, 641. 97. Rabin, A. I. a King, G. Psychological studies in schizo- phrenia. In L. Bellak (Ed.), Schizgphrenia. New York: Lages Press, 1958. 98. Reisman, J. M. Response differences between process and reactive schizophrenics as induced by magazing photo- graphs. Unpublished doctoral dissertation. Michigan State Univ., 1958. 99. Reynolds, B. & Adams, J. Effect of distribution and shift in distribution of practice within a single training session. J. exp. Psychol., 1953, $5, 137-145. 103 BIBLIOGRAPHY (cont.) . Richter, D. Biochemical aspects of schizophrenia. In D. Richter (Ed.), Schizophrenia: somatic aspects. New York: Pergamon Press, 1957. 53-75. . Richers-Ovsiankina, M. Studies in the personality struct- ure of schizophrenic individuals: II reaction to inter- Immted tasks. J. gen. Psychol., 1937. 15. 179-196. Sands, D. E. Endocrine changes in schizophrenia. In D. Richter (Ed.), Schizophrenia: somatic aspects. New York: Pergamon Press, 1957, 77-91. Selye, H. The stress 2; life. New York: McGraw-Hill, 1956. Shakow, D. Eye-hand coordination in schizophrenic patients and normals as measured by the pursuit meter. Psychol. Bull., 1932, 32, 662. Shakow, D.,A study of certain aspects of motor coordin- ation in schizophrenia with the prod meter. Psychol. Bull., 1932, 52, 661. Shakow, D. a Huston, P. E. Studies of motor function in schizophrenia: III steadiness. J. gen. Psychol., 1946, 5_, 119-126. Shipley, W. C. Studies of catatonia: VI. Further investi- gation of the perseverational tendency. Psychiat. Quart., 1934. Q. 736-744. Snoddy, G. S. Evidence for twoo opposed processes in mental gpowth. Lancaster: Science Press, 1935. Stanton, A. In discussion of Freyhan' s article. Amer. J. Psychiat., 1955. 112,167. Starkweather, J. & Duncan, G. A test for conditioned inhibition in motor learning. J. _§p_. Psychol., 1954, _I. 351- 356. Strecker, E. a‘wiley, G. Prognosis in schizophrenia. In Schizophrenia (Dementia praecox). Assoc. for Research in Servous a Mental Diseases, Vol. V. New York: Hoeber, 192 . Strecker, E., Ebaugh, F. & Ewalt, J. Practical clinical psychiatry. Phila.: Blakistcn Co., 1951, 506. Sullivan, H. S. Schizophrenia: its conservative and :malignant features. Amer. J. Psychiat., 1924, 5;, 77-91. 104 114. 115. 116. 117. 118. 119. 120. 121. 122. 123. 124. 125. 126. BIBLIOGRAPHY (cont.) aflJivan, H. S. Conceptions g§_modern psychiatry. Wash.: The William Alanson White Foundation, 1947. inlton, J. R. The use of instrumental motor and verbal learning techniques in the treatment of chronic schizo- pmrenia. Unpublished doctoral dissertation, Michigan State Univ., 1956. Travis, R. Practice and rest periods in motor learning. :10 P82011010, 1937, 2, 183-1870 weaver, J. An experimental investigation of the compara- tive effect of massed and spaced pre-rest practice upon both massed and spaced post-rest performance on the pursuit rotor task. Unpublished masters thesis, Michigan State Univ., 1950. White, R. The abnormal personality, a textbook. (2nd ed.) New York: Ronald, 1956. Williams, M. Psychophysiological responsiveness to psychological stress in early chronic schizophrenic reactions. Psychosom. Med., 1953, 15, 456-462. Wing, C. & Ammons, R. B. A theoretical formulation of the effects of motivation on rotary pursuit performance. Mot. Skills 3%.. EXChc, 1950, a, 44-470 Wittman, Mary & Steinberg, D. L. A study of prodromal factors in mental illness with special reference to schizophrenia. Amer. J. Psychiat., 1943/44, 100, 811-816. Wittman, Phyllis.Scale for measuring prognosis in schizo- phrenia. Elgin State Hosp. papers, 1941, 4, 20-33. Wittman, Phyllis. Follow up on the E1 in prognostic scale results, III. Psychiat. J., 19 , 4, 56-59. ‘Wittman, Phyllis. Diagnostic and prognostic significance of the shut-in personality type as a prodromal factor in schizophrenia. J. clin. Psychol., 1948, 4, 211-214. ‘Woodworth, R. Experimental psychology. New York: Holt, 1938. hhfiLfeck, W. H. Motor function in the mentally disordered, I. 11 comparative investigation of motor function in psychotics, psychoneurotics, and normals. Psychol. Rec., 1 941 , fl, 271-3230 105 UPMIX 106 Scale of Apparent Psychosis Subject Ward Date Rater ;: I I “11L 4 No readily Evidence of psychotic EVidence of lit- discernible thinking and behavior, tle else but evidence of and of non-psychotic psychotic think- psychotic thinking and behavior ing and behav- thinking or about equally divided ior; no readi- behcvior; 1y discernible non-psychotic thinking and behavior read- ily discern- ible evidence of non- psychotic think- ing and behav- ior. 107 Becker's Revision-Elgin Prognostic Scale The definitions for the subscales of the Elgin Prognostic Scale and modified by the writer for use in this study are given below. Items A through 0 are rated on the basis of anamesis data. Items P through T are rated on the basis of the presenting clinical symptoms. A. Defects of interest versus definite display of interest. 0. Keen ambitious interest in some of the following: home, family, friends, work, sports, arts, pets, gardening, social activities, music, dramatics. 2. Moderate degree in several activities including social gatherings, sports, music, opposite sex, etc. 4. Mild interest in a few things such as Job, family, quiet social gatherings. The interest is barely sustaining. 6. Hithdram and indifferent toward life interests of average individual. No deep interests of any sort. B. Insidious versus acute onset. 0. Development over a period of 0-1 months with sudden, dramatic divorcement from more or less commonplace living. 1. Development over a period of 2-4 months with marked personality changes from relatively commonplace living. 2. Development over a period of 5-7 months with moderate personality changes. may be some accenting of previous trends, but changes also. 3. Changes have taken place over a period of 8—12 months with noticeable personality modifications, but primarily an accenting of existing trends. 4. Slow development of symptoms but possible to detect personality changes in the 2 years prior to onset. 6. Very slow development of symptoms so that the final disorder appears as an exaggeration of already strongly accentuated personality traits. Indications even prior to adolescence. C . Shut-in-personality . General: The psychotic condition is simply an exagger— ation of the peculiar type of personality shown all through childhood. Stormy childhood often with over-protection and a difficult adolescence characterized by inability anxiety, to get along and mix with other children. Constitutional 108 apparently, rather than product of specific environment. 5. Very much as described above. 3. Mbderately the picture described above. 1. Only mildly this way, but some resemblance to pattern. 0. Apparently normal childhood, little evidence of shy— ness, unusual difficulty or else unusual behavior is attributable to environmental factors. D. Schizothymic versus syntonic personality. 0. Very sociable, fond of people and social gatherings; many friends, active in groups and sports, participates in life of his community. 2. Mbderately sociable, likes people and social gather- ings, but doesn't go far out of way to meet people. 3. Mildly shy, mildly sociable. Will interact when the situation presents itself. Prefers association in family group as a rule. 4. Hbderately shy, retiring, etc. More concerned with ideas than people. 6. Very seclusive, shy, retiring, mixes little with others. Few if any close friends. Interested in ideas rather than people. Passive onlooker at life rather than an active participant. Poor "bite on life“. E. Range of interests. 0. Wide and varied interest, keen bite on life and its opportunities, forward and interested in making adaptation to daily life in many spheres. 2..M0derate breadth of interest, interested in making adaptations to daily life, but does not go out of way to seek new opportunities. 4. Mbderate restriction of interests. Narrow goals, but some detectable variety of interests within a narrow orientation. 6. Inadequate interest in varied problems of life, rigid, narrow goals or interests, circumscribed activities because of the narrqw range of interests. F. Constitutional bias. 0..A healthy, strong energetic physical and mental makeup 109 that makes the interplay between heredity and environmental influence during childhood a satisfactory one. 2. Suggestions of defects in physical and mental stamina occasionally observed. Not at all marked. Perhaps proneness to repeated illnesses in childhood. 4. Regarded from early childhood as different, queer or odd; perhaps associated with some real defect or handicap- physical such as deformity, or speech defect, but more often only an imaginary defect of personality. G. Low energy tone. 0. Very strong drive, keen active and alert interest and ambition shown in school, social and work spheres. Good grasp on life, liked life and had energy enough to enjoy it. Outgoing and adequate in meeting life. '19-?!" - £31. III. _ "I \M y 2. Moderately adequate drive, interest, energy as des- cribed above. a 4. Mbderately inadequate energy tone. Tends toward sub- missive, passive reactions. Shows some potential to face life's problems, but would rather avoid them than expend the necessary energy. 6. Submissive, inadequate passive reactions, weak grasp on life, does not go out to meet life's problems, does not participate actively but passively, accepts his lot without having the energy to help himself. H. Asthenic build. 0. Large, barrel-shaped trunk, with relatively short legs and arms; shield shaped face, short broad head upon a thick neck, set well down between shoulders. 2. Athletic build. Balanced weight, good musculature, head shape, etc.; intermediate to O and 4. 4. Long, slender extremities with relatively small, narrow trunk. Egg-shaped face ; elongated narrow head on a tall, slender neck. I. Heterosexual contact. 0. Purposefully contacts the other sex, dates frequently, makes successful effort to be attractive in manner, dress, accessories, etc. so as to be popular with girls (boys). 2. Dates when situation affords. Maybe marries, but has difficulties in compatibility. Wants to interact with other sex, has some techniques, but not completely successful. 110 3. If married, apt to divorce or separate. Generally this is rated as a midpoint between 2 and 4. 4. Moderate lack of heterosexual contact. Tends to avoid dates, dances, but has on occasion participated in same. lflght think he (she) would like to marry some day, but little enthusiasm for it. 6. No association with the opposite sex. Never had any dates. Avoids dances and social gatherings which require the intermingling of boys and girls. J. marked academic interests versus active interest in sports. 0. An active interest in sports, participates in baseball, basketball, tennis, football, or other sports. A solitary sport such as swimming or golf is not so important unless the patient plays or sw1ms with others rather than self. 1. Moderate interests in sports, and other interests. 2. Mild interest in sports, mild interest in study. ‘3. Moderate interest in study-~without other interests. 4. Fond of study, worked diligently at school and excels in this field associated with inadequacy in sports and social field, a grind without the ambition or drive in work and play to equal his achievements as a student. K. Careless indifference versus worrying, self-conscious type. 0. Subjectively sensitive, critical of self, preoccupied with own conflicts, but shows little of the extreme, bizarre, unusual, mysterious or socially unacceptable behavior. 2. Some concern and preoccupation with difficulties- a moderate position to O or 4. 4. Withdrawal and disinterest in social surroundings, careless of social requirements, given to day-dreaming and excentricity, dirty, disheveled appearance, profane language, unacceptable habits. L. Exclusive stubborn traits versus insecurity and inferior- ity feelings. O. Timid, lacks self confidence, feels insecure and in- ferior. Very sensitive and critical of self; feels certain problems in life but participates and does not accept his lot passively or without regret and struggle. l. Mbderately like 0. 111 2. Neither timid nor stubborn. 3. Moderately stubborn. 4. Complete withdrawal from surroundings and interest, inadequate in meeting life but stubborn and opinionated, refuses to change, even if suggested, to achieve a more adequate adjustment. Opinionated and egocentric. M. Toxicity or eXhaustion. 0. History of illness, disease or eXhaustion closely associated with the onset of psychotic symptoms. 1. Illness present, not severe, but related to onset. Less severe eXhaustiqn. 2. Poor health--but not requiring bed. 3. Fair health--a little run down. 4. Excellent health history. Health in no sense an etiologic factor in the development of psychosis. N. Precipitating conditions. (Situational reaction) 0. A strong relationship between onset of symptoms and situational problems that would require definite and continued effort to adjust satisfactorily; i.e. death, failure, loss, interpersonal strife. The average person would definitely try to flee such a situation rather than attempt to change it. 1. marked stresses related to onset, but not as severe as O. 2. Moderate stresses related to onset such as financial jproblems, interpersonal discord, etc. which would cause considerable worry to the average individual. 3. Mild stresses that the average person would react to in.some way but would not usually lead to a breakdown. 4. Onset of psychotic symptoms not related to any dis- ‘turbance or difficulty in the patients situation- or a dis- turbance of such a trivial nature that it would be ignored or’quickly forgotten by the average person. 0. ration of psychosis. 0. Under 2 months 1. 2-4 months 2. 4-6 months 3. 6-8 months 112 S. 1-2 years 6. 2-3 years 7. Over 3 years The following scales are rated from the presenting clinical picture. P. 'Inadequate affect versus emotional instability of appropriate affect. O. Adequate or overly demonstrative affective expression. This includes appropriate expression and manic depressive aspects in which there is a facile display of emotion. 2. Moderately inadequate affect. Tends to be rigid, dull, or slightly inappropriate. Only moderate responsiveness to emotional stimulation. 4. Markedly inadequate, inappropriate, rigid or dull affect. Emotional life expressed is at odds with behavior or strikingly inappropriate. Little reaction to stimulation of any strength. Q. Hebephrenic symptoms; extreme indifference, complete divorce between ideas and affect; extreme carelessness in appearance and reaction with untidiness in some cases, silly behavior, often silly laughter without appropriate stimulation. 0. Not as above. 1. Mildly as above. 2. Moderately as above. 3. Markedly as above. 4. Very markedly as above. Rt Ideas of influence; patient feels that someone or some- thing is directing his actions, thoughts, or speech. Some outside influence forces him to do things even against his own will. 0. Not as above. 1. Mildly as above. 2. Moderately as above. 3. Markedly as above. 4. Very markedly as above. 8. Physical interpretation delusions. The patient has cer- ‘tain feelings (possibly hallucinations) that are linked up *with definite delusional ideas; for instance, that there is as snake in his stomach, that food passes right through his ‘body, that someone is passing electrical currents through his body, that the food he eats is poisoned, etc. 0. Not as above. 1. Mildly as above. 113 2. Moderately as above. 3. Markedly as above. 4. Very markedly as above. T. .Atypical symptoms. Manic or depressive feature mixed with the schizophrenic picture. Display of appropriate affect, over-talkative, distractive, facetious, display of interest in other patients, desire to help humanity in general, depression, feelings of sin or guilt, psychomotor retardation, anxiety, crying. 0. Very markedly atypical picture, shows many of the above features with considerable strength of affect. l. Markedly atypical picture. 2. Mederately atypical picture, less intensity of features shown. 3. Mildly atypical picture, unusual features are minimal or lacking in intensity. 4. Lacking atypical features. 114