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Copyright by C) GERALD DENNIS JUHR 1980 DEVELOPMENT OF AN MMPI SUBSCALE PREDICTING OUTCOME OF MULTIDISCIPLINARY TREATMENT FOR CHRONIC LOW BACK PAIN BY Gerald Dennis Juhr A DISSERTATION Submitted to Michigan State University in partial fulfillment of the requirements for the degree of DOCTOR OF PHILOSOPHY Department of Counseling, Personnel Services, and Educational Psychology 1980 ABSTRACT DEVELOPMENT OF AN MMPI SUBSCALE PREDICTING OUTCOME OF MULTIDISCIPLINARY TREATMENT FOR CHRONIC LOW BACK PAIN BY Gerald Dennis Juhr The primary intent of this study was to explore the feasibility of developing a subscale of items from the Minnesota Multiphasic Personality Inventory for use in predicting outcome of treatment for chronic low back pain. Previous use of the MMPI in personality assessment of chronic low back pain patients repeatedly has confirmed the presence of psychoneurotic involvement among a major- ity of such patients and strongly indicated that higher levels of pre-treatment involvement are positively cor- related with unsuccessful treatment outcome. Here the attempt was made to develop an MMPI subscale enabling more effective screening, diagnosis, and matching of these patients with treatment strategies and resources. Subjects for the study were 185 former in-patients of a multidisciplinary back pain clinic, whose treatment had consisted of neurosurgical (facet injection and facet rhizotomy), psychological (EMG biofeedback and other muscular relaxation procedures), and physical therapy. Gerald Dennis Juhr Subjects were assigned treatment outcome status based on their responses to a mailed questionnaire, the Pain Survey, which had been constructed and piloted expressly for this research. Of these subjects, two-thirds were randomly . selected to comprise a scale-development subsample, and the remaining one-third became the cross-validational sub- sample. The former subjects' MMPI records were analyzed by chi-square to determine which items best discriminated between successful and unsuccessful subjects. ‘The 24 best items constituted a tentative Back Treatment Success Scale, whose ability to discriminate among members of the cross- validational subsample was then tested by comparing mean scale scores of successful and unsuccessful subjects with a one-way analysis of variance. This test proved statis- tically non-significant. This result was at least partially attributable to the size of the scale-development subsample. Therefore, to provide as comprehensive a basis as possible for future research, the two subsamples were pooled and the chi-square test of item-discrimination was applied to the total sample population. This yielded a total of 45 items discriminat- ing at the .05 and .10 levels; these were examined for standard MMPI-scale membership, categorized on the basis of content, and statistically factor analyzed. Gerald Dennis Juhr The majority of the items belonged to just four of the standard MMPI scales, the Depression, Psychopathic Deviate, Schizophrenia, and F scales, though all scales were represented by at least two items. Item-categoriza- tion based on content permitted identification of the following factors related to unsuccessful outcome: (1) denial of social non-conformity, (2) self—deprecatory attitudes tending to guilt and paranoia, (3) health com- plaints and disease phobia, (4) impaired faculties of con- centration, coordination, and awareness, (5) depressed affect and behavior, (6) repressed hostility and authority problems, (7) non-affirmation of fundamentalist religious beliefs, (8) attraction by members of same sex, and (9) excessive use of alcohol. Statistical factor- analysis of the 45 items led to identification of eight response-profiles that appeared similar to personality profiles frequently associated with chronic low back pain patients. Among these were hypochondriasis, reactive depression, somatization, manipulation for secondary gain, family conflict, and relative freedom from psychopathology (low rate of item-endorsement in unsuccessful direction). These findings were not cross-validated on another sample. The coincidence of the content- and factor- analyses with previous research findings, however, suggests that the 45 items here selected and examined may provide a valid basis for the eventual development of such a sub- scale as was here intended. To my forthright and loving parents, Hans and Anita, who have dedicated so much to my growth and education and To my dear wife, Janneke, beneficent helpmeet ii ACKNOWLEDGEMENTS Tibetan therapeutic lore maintains that there are three pre-requisites to any successful treatment -- the belief of the patient, the belief of the healer, and the right relationship between patient and healer. This dictum was at least in part substantiated by the research reported Vin the following pages. At this point, however, I wish to acknowledge the "right relationships" -- the favorable disposition and actions of many persons other than myself -- which proved vital to the successful treatment of this dissertation. I am truly grateful to them. The conception and design of this research resulted from conversations with John Jerome, Ph.D., psychologist of the Ingham Low Back and Pain Clinic. He and James Bullock, M.D., the clinic's orthOpedic surgeon, encouraged me to undertake this project and did much to make it possible. They solicited their patients' co-operation, and allowed me access to their records. I was made to feel welcome in their offices and given timely assistance by their clerical staff. Many chronic pain patients whom I have never met responded to the survey. Some shared their continuing iii. pain; others shared their relief. Their willingness to communicate was indispensable, and is sincerely appreciated. The guidance of Dr. James Engelkes greatly improved the quality of this undertaking and assured its successful completion. Likewise, Drs. Gregory Miller and Bob Winborn gave generously of their time to serve on my guidance committee and review my research. My special thanks to Lee Burkhardt for her competent, efficient preparation of the manuscript. Friends and colleagues at the University Centers for International Rehabilitation with their daily interest and assistance made this work more enjoyable and sustained my spirits. I shall especially remember the wit and patience of Jim Mullin, who taught me to speak without expletives to the computer, and the personal warmth and camaraderie of Madan Kundu, Denise Tate, Bill Frey, Ron Wolthuis, Paul Schneider, Bob Jarvis, and Owen Dailey. I remain indebeted to Don Melcer, friend and mentor, who valued the differentness of the educational paths I have taken, and whose steadiness and example helped me negotiate the path through graduate school. During this time Don's wife, Eleanor, watched over my family's welfare and contributed often to our happiness. Our growing friendship with David and Peggy Rolfe added a stimulating, much appreciated dimension to my iv family's life during the past year of labor, and banished often the lurking specters of obsession and depression. David also spurred my professional development in many ways that have helped me anticipate an active professional life. Most of all I wish to acknowledge the devotion and understanding of my wife, Janneke, and our children, Niels and Fiona. We have come this far together, and I intend to share with you more completely, joyfully, the adventures still before us. TABLE OF CONTENTS LIST OF TABLES . . . . . . . . . . . . Chapter I. II. III. IV. THE PROBLEM . . . . . . . . Purpose . . . . . . . . . Importance of the Research Definition of Terms . . . . Summary and Overview . . . REVIEW OF LITERATURE . . . The Human Experience of Pain Personality Inventories and of Chronic Low Back Pain Treatment Studies . . . . . Implications and Summary . METHOD OF RESEARCH . . . . Experimental Sample . . . . Instrumentation . . . . . . MMPI . . . . . . . . . . Pain Survey . . . . . . Procedure . . . . . . . . Statistical Analysis . . . ANALYSIS OF RESULTS . . . . Pain Survey . . . . . . . . Back Treatment Success Scale Sufferers Re-analysis of Data for Total Sample Population . . . . . . . Summary of Results . . . . DISCUSSION OF RESULTS . . . Summary . . . . . . . . . . Discussion . . . . . Limitations of the Study . Implication for Future Research . . . Conclusions . . . . . . . . vi Page viii 10 11 13 14 21 30 38 41 42 44 44 47 49 57 60 61 62 67 82 84 84 86 95 98 101 APPENDICES REFERENCES Pain Survey . . . . . . . . Cover Letter Accompanying Pain Endorsement Percentages for MMPI Form—R Items by Successful vs. Loadings on Eight Factors of 4S MMPI Form-R Items Discriminating Between 76 Successful and 109 Unsuccessful Patients Treated Survey . . . . . . . . . Unsuccessful Subjects (N = 185) for Chronic Low Back Pain vii Page 103 103 105 106 113 114 LIST OF TABLES Table Page 3.1 Pilot Study of Pain Survey; Ability of Individual Foils to Discriminate Between Successful and Unsuccessful Former Patients . . . . . . . . . . . . 52 3.2 Comparison of Demographic Data Obtained from Pilot and Research Samples . . . . 55 3.3 Endorsement of Criterion Questions by Pilot vs. Research Samples . . . . . . 56 4.1 Response to Pain Survey of Treatment Success and Treatment Failure Groups . 63 4.2 Back Treatment Success Scale; Direction of Item Response Endorsed More Frequently by Successful vs. Un- successful Subjects (N = 185) . . . . . 65 4.3 Analysis of Variance of Back Treatment Success Scale Scores of 26 Successful and 36 Unsuccessful Subjects . . . . . 66 4.4 Scale Categorization of Items Dis- criminating at .10 Level Between 76 Successful and 109 Unsuccessful Back Clinic Patients (N = 185) . . . . . . . 68 4.5 MMPI-Item Loadings on Factors Related to Successful/Unsuccessful Treatment Outcome . . . . . . . . . . . . . . . . 76 4.5.1 Factor 1: Hypochondriasis . . . . . . . 76 4.5.2 Factor 2: Organic . . . . . . . . . . . 77 4.5.3 Factor 3: Manipulative . . . . . . . . . 77 4.5.4 Factor 4: Reactive Depression . . . . . 78 4.5.5 Factor 5: Familial Conflict . . . . . . 78 viii Table Page 4.5.6 Factor 6: Somatization . . . . . . . . . . 79 4.5.7 Factor 7: Hypochondriasis . . . . . . . . 79 4.5.8 Factor 8: General Neurotic . . . . . . . . 80 ix CHAPTER I THE PROBLEM Americans spend more than 100 billion dollars per year on health care. Of this amount, nearly 13 billion dollars is spent by persons seeking relief from chronic low back pain (Fordyce, 1976a), while the national yearly cost of related compensation, lost wages, and lost potential tax revenue conservatively may be estimated at an additional 25 billion dollars (Leroux, 1979). It is evident that in the United States, the reported frequency of low back injuries is increasing decade by decade (Sternbach, Wolf, Murphy, and Akeson, 1973b). There is an evergrowing popula- tion of chronic low back pain patients who have failed to respond to medical, physical, and psychophysiological treat- ments for relief of pain (Bonica, 1976; Kraus, 1976; Melzack, 1973; Shealy, 1976), and disproportional payments for this one syndrome are seriously jeopardizing the functioning of employment compensation programs (Finneson, 1976). Russek (1955) reported that in 1955 chronic low back pain sufferers accounted for 12.4% of all industrial injuries and 16% of all compensation payments in the State of New York. Statistics from the State of Washington Department of Labor and Industries (McGill, 1968) revealed that back injuries constituted 5% of industrial claims, 12% of contested settlements, and 24% of days lost. In the State of California in 1970, 37.8% of all newly filed industrial claims were based on low back pain, and this percentage of back settlements had steadily increased from 29% in 1961 to 39.3% in 1969 (Osterloh, 1971, cited in Sternbach et a1., 1973b). Comparatively, from 1971-1973 in the Commonwealth of Pennsylvania only 9% to 11% of industrial injuries were classified as low back injuries, but 30% to 40% of all compensation payments were for low back pain (Bureau of Vocational Rehabilitation, Common- wealth of Pennsylvania, cited in Finneson, 1976). More recent statistics cited in the Rehab Brief (University of Florida Rehabilitation Research Institute, 1978) showed that claims related to low back pain account for 85% of California's workmen's compensation medical budget. According to Department of Labor Statistics of the State of Michigan (Pinto, 1979), lower and upper back injuries comprised the largest single class (24.5%) of industrial injuries. Such findings also point to the significance of chronic low back pain as a rehabilitation problem. Finneson (1976) reported that 281 low back pain patients receiving employment compensation and successfully treated by nonsurgical means averaged 36 days of total disability per episode. White (1969) found that 4 years after surgical treatment, only 39.5% of low back pain patients had re- turned to work comparable to that performed prior to surgery. Despite the frequency and persistence with which this syndrome has been presented to the medical profession, and despite its enormous consequences to the individual sufferer and to society, chronic low back pain "...remains a baffling, frustrating, and elusive problem to clinical practitioners" (Blumetti and Modesti, 1976). A recent important response to this problem has been the upsurge of interest in a multidisciplinary pain clinic approach to complex chronic pain problems (Bonica, 1976). These clinics combine in an inpatient setting several treatment modalities such as orthopedic surgery and neurosurgery, chemotherapy, relaxation therapy, individual and group counseling, withdrawal of analgesic medication, exercise, physical therapy, and regulation of diet (e.g., Sternbach, 1974; Shealy, 1976; Pheasant, 1972). Increasingly, as part of this development, the discipline of psychology has been called upon to explain chronic low back pain as a psychophysiological condition with substantial psychological components. Treatment pro- grams have incorporated such diverse approaches as operant conditioning (Fordyce, 1976b), psychoanalytic counseling (Sarno, 1976), biofeedback and relaxation techniques (Shealy, 1977; Bullock, Jerome and Pool, 1975), life— situational counseling (Sternbach, 1974), and family- oriented treatment (Hudgens, 1979) in the attempt to ameliorate chronic pain. Reported success rates of 60 to 75% have confirmed the efficacy of these interventions. Nevertheless, even with intensive screening to eliminate the especially poor candidates, 25 to 40% of patients seen in these clinics failed to achieve significant relief from pain (Shealy, 1977; Sarno, 1976; Bullock, 1977). These "low back losers" as one clinical team (Sternbach et al., 1973b) has termed them, continued to seek treat- ment, but consistently failed to find relief from their pain; moreover, each subsequently unsuccessful treatment further complicated their problem (Shealy, 1976; White, 1966) and further reduced the odds for recovery (Wilfling, Klonoff, and Kokan, 1973). Clearly, there is a growing pool of chronic low back pain sufferers who have failed and who continue to fail to respond to the available resources of the healing profession. Further investigation of factors related to failure, and to success, appeared warranted. Purpose The purpose of this study was to investigate the psychological (personality) characteristics of those persons who succeed, and those who fail, in multidisciplinary inpatient treatment for chronic low back pain. Patients' pre-treatment responses to The Minnesota Multiphasic Personality Inventory (hereafter: MMPI) were statistically analyzed to determine which items significantly differen- tiated between patients with successful and those with unsuccessful outcomes. These significantly differentiat- ing items comprised a Back Treatment Success Scale, a subscale of MMPI items designed to predict success or failure in treatment for chronic low back pain. Additionally, the items selected were examined on the basis of content to facilitate identification and discussion of factors related to success or failure in treatment. Importance of the Research The past four decades have witnessed a growing awareness by health care professionals that the onset of, reaction to, and outcome of treatment for chronic low back pain are in many cases highly dependent upon psychological factors (e.g. Fetterman, 1937; Sargent, 1946; Sullivan, 1955; Yochelson, 1966). The need for an empirically de- veloped psychological test predictive of individual out- come of treatment for this syndrome has been recently dis— cussed (Waring, Weisz, and Bailey, 1976). These authors reviewed and attempted to validate extant treatment studies in which outcomes were correlated with patients' psycho- logical characteristics, and stated that results were in- conclusive and of doubtful clinical validity. Indeed, few such studies have been published. One major study in this review (Wiltse and Rocchio, 1975) and one not included (Lippincott, 1976) were unfortunately conducted on a sample of patients whose low back pain had been treated by chemonucleolysis, a chemo-surgical procedure later proven ineffective except as a placebo (Martins et a1., 1978). The purpose of Lippincott's (1976) study, the development of an MMPI subscale predictive of treatment outcome, was synonymous with that of the present research. The fact that the treatment enjoyed by her sample later proved to be a placebo, is definitely of interest, and her study is worthy of reinterpretation in light of this finding. Nevertheless, an important need remained to be met through the development of such a scale based on treatments of proven effectiveness. The medical and psychological treat- ments administered to patients in this study (EMG bio- feedback with or without facet rhizotomy) are of proven effectiveness (Shealy, 1977; Bullock, Jerome, and Pool, 1975; Bullock, 1977; Jerome, 1978). Several potential clinical applications of such a scale have been suggested. First, multidisciplinary teams could utilize such an assessment tool in their evaluation of patients for treatment. McGill (1968, p. 176) has stated that improper evaluation of the "subjective com- plaints of compensation patients with low back pain creates great adverse psychological effect on the already anxious, apprehensive patient, with the result being prolonged absenteeism." Hoover (1968) of the Mayo Clinic has stated that psychiatric illness may prevent a patient from obtain- ing the intended relief from surgery. "Evaluation of the contribution of emotional instability to the patient's pain is by far the most difficult problem and the source of greatest error in making a decision to fusion." (p. 192) White (1966) has maintained and Wilfling et a1. (1973) systematically have demonstrated that each successive un- successful surgery reduces the probability that a patient will ultimately experience relief from chronic low back pain. This correlation may be due to somatic complica- tions (irritating scar tissue, post-operative pain) as mentioned by Shealy (1976), or to the psychological con- sequences of failure (learned helplessness, somatic pre- occupation) as suggested by Sternbach (1974), or to a learned life-style (White, 1966), or simply to the intractability of the physical condition, a suggestion which no one has made except in certain categories of clearly identifiable organic pathology (e.g. infection, neoplasm, rheumatoid diseases); the fact remains that practical identification of crucial psychological factors would assist a pain specialist in the decision to recommend surgery or not. Second, the identification of psychological factors associated with treatment failure may lead to the recommendation that a patient undergo intensive counseling prior to re-application for surgical procedures (Sternbach, 1974). Either the counseling component of the regular treatment program may be expanded to accommodate certain individuals, or extramural referrals can be made. Such a procedure emphasizes the best matching of patient with treatment and facilitates the optimum use of available rehabilitation resources. Third, the collection of psychological data may provide an opportunity for realistic discussion with the patient of factors which could impede efforts to seek relief from pain (Sternbach, 1974). Many chronic pain patients have little or no conception of psychosomatic dysfunctions and easily assume that any mention of emo- tional factors is an attempt to convince them that their pain is "imaginary," "all in their heads," or "just nerves." Reference to patients' scores on an objectively scored, normed personality inventory may provide a bridge to the discussion of cognitive, emotional, and motivational factors affecting the experience of pain. When this occurs, patients can begin to accept responsibility for their role in the maintenance or eradication of pain, an aspect of treatment deemed highly important under the holistic or "whole person" approach to treatment espoused by numerous pain clinics (Shealy, 1976; Jerome, 1978). Fourth, an expeditious evaluation may enhance the likelihood that patients will return to productive activity before becoming massively conditioned to pain. Lamaze (1970) has described the work of Pchonick and of Rogov, who in separate experiments were able to condition subjects to experience a neutral stimulus as painful, and a painful stimulus as pleasant. In sufferers of chronic pain, such conditioning eventually contributes not only to the per- vasiveness of the experience of pain, but also to the in- creasing attempts to withdraw from activities associated with pain (Fordyce, 1976b). Effective reinforcement in such cases is forthcoming from secondary gains either in the form of compensation payments (Finneson, 1976) or in the form of sympathy or other considerations shown a "sick" person (Foster, 1964). A quickly administered test allowing timely diagnosis to interrupt or prevent the adoption of such a lifestyle may be considered a worthwhile contribution to the fields of pain treatment and research. The challenge and the importance of devising such an instrument has been well summarized by Thomas and Lyttle (1976). These authors have noted that "...certain patient personality profiles on the MMPI appear closely associated with chronic complaints of low back pain [and that] predictions made from psychological data were more accurate than predictions based solely on the physical conditions of the patients...[0]ne would expect psychological assessment to be well inte- grated into the diagnostic procedures of medical therapy programs that involve 10 patients with complaints of low back pain. However, psychological evaluation is not a routine part of diagnostic procedures, probably because there is no single reliable and easily identifiable psycho- logical variable that predicts prognosis with as much accuracy as the clinical judge- ment of a psychologist based on multiple psychological tests and an interview. The problem then is the fact that many orthopedists in general practice do not have easy access to a psychologist's evaluation of their patients." (p. 125) The attempt was made in this study to develop a diagnostic scale based on reliable psychological variables. Whether or not this attempt was entirely successful, the empirical derivation of factors related to treatment outcome may be viewed as a worthwhile contribution toward the development of such a diagnostic tool. Definition of Terms Chronic low back pain - Operationally is pain described by the patient as moderate to severe, that has been persistent for six months or longer, and has failed to respond to medical, physical or psychological treatment (Jerome, 1978). Nosologically is pain situated in the lumbosacral region at the level of the third, fourth and fifth lumbar vertebrae and the sacrum, which is not the result of fractures, neoplasms, infective lesions, congenital anomalies, or diseases referred from other organic systems (Thomas and Lyttle, 1976). 11 Facet Rhizotomy - Is a technique which involves thermo- cautery to produce denervation at the facet joint. Facet denervation attempts to block neural trans- mission at the origin of the pain. Psychological variables - Refers to cognitive, affective/ evaluative, and motivational factors residing within the individual that can be perceived, ob- jectively described, and measured, the organization of which modulates the individual's experience of pain and differentiates him/her from other persons. Summary and Overview This study has been designed to explore the rela- tionship between relief from chronic pain and individual psychological variables. Clinical research and practice suggest that such variables play an important role in modulating the human experience of pain and in affecting the outcome of treatment for relief of chronic pain. A more thorough understanding of this relationship is warranted. The procedures followed in this study have been intended not only to lead to an identification of such critical modulating variables, but also to result in the development of an MMPI subscale capable of practical application in the prediction of treatment outcomes for chronic low back pain. 12 This chapter has presented evidence of the potential viability and practical utility of such a study. Chapter II reviews current theory ascribing a decisive role to psychological variables in the human experience of pain. Findings resulting from the previous use of personality inventories with chronic low back pain patients are reviewed, with primary attention to those studies incorporating the MMPI, the inventory used in the present study. The majority of such studies have demonstrated the validity and reliability of the MMPI as an indicator of psychophysio- logical involvement and treatment prognosis of patients having chronic low back pain. The sample population, research procedures and design of this study are the tOpic of Chapter III, the statistical results of the research the topic of Chapter IV. These results are then discussed in Chapter V, with particular attention to their implications for treatment and future research. CHAPTER II REVIEW OF LITERATURE That psychological variables play a significant role in the origin and longevity of the syndrome known as chronic low back pain has been reported with increasing frequency in the literature of the past four decades. The particular action and interaction of these variables has been the subject of considerable recent research. A more complete understanding of these processes and the applica- tion of this knowledge to clinical practice is the subject of the present study. To better understand the role of psychological factors in the human experience of pain, it is necessary to review the various theories of what pain really is. The review leads to the Melzack and Wall (1965) formulation of the Gate Control Theory of Pain, which described a physiological basis for the role of psychological (cognitive, affective, and motivational) variables in the pain process. The first section of this chapter therefore re- capitulates the Melzack and Wall conceptualization as a basis for understanding pain as a multidimensional ex- perience, involving both physical and psychological domains. 13 14 The second section summarizes the research relating chronic pain in general and chronic low back pain specifically to individual personality factors. The final section reviews previous studies which have utilized standardized per- sonality inventories to investigate the interaction be- tween personality variables and the outcome of treatment for chronic low back pain. The Human Experience of Pain The common view of pain is that it is a biologically useful sensation informing the organism of potential or actual damage or harm. The neural links between an organism's sensory capacity and its motor capacity enable the transmission of pain signals to activate the organism to respond, either by defensively removing itself from the noxious stimulus or by aggressively dealing with its source. Pain has traditionally been conceptualized by scientific investigators as an objective stimulus related to noxious levels of warmth, pressure, etc., which is transmitted by neural pathways to the subjective potential (brain) of the organism. In fact, the traditional approach of science has sought to explain all human perception in terms of direct linear causality and to investigate it by the increasingly refined dissection of the neurological systems responsible for the transmission of sensation from sensing organ to perceiving brain (Steiner, 1962). Man 15 has thus been considered a passive recipient of impressions from an objective world external to him. Within such a framework, pain has been viewed as a strictly physiological sensory experience. Typical of such conceptualizations of pain were the specificity theories, which defined pain as a primary sensation with special peripheral receptors, neuronal trans- mitters, and receivers in the central nervous system. The pathway from periphery to center was seen as an uninterrupted transmission system, with the intensity of perceived pain in direct proportion to the intensity of the stimulus applied. The relevant peripheral receptors were believed to be specialized for the sensation of pain and distinct from other main groups of sensory receptors, for instance those for mechanical or thermal stimuli. The specificity theories cannot account for the vast individual differences in subjective perception of a constant noxious stimulus. The subjective report of pain is a notoriously unreliable measure of objective stimula- tion (Sternbach, 1974). Even though these theories have proved to be of heuristic value in research on the mechanics of pain transmission, the deficiencies of the theories are serious. Melzack and Wall (1965) have placed specificity theory in the following perspective: Physiological specialization is a fact that can be recognized without acceptance of the psychologic assumption that pain is deter- mined entirely by impulses in a straight- 16 through transmission system from the skin to a pain center in the brain. (p. 972) Pattern theories arose in response to the defi- ciencies of specificity theory. These theories stated that information generated by peripheral receptors is coded in the form of patterns of nerve impulses. The peripheral receptors are sensitive to pain, a separate system of neuronal fibers transmits the information to the brain, and the brain interprets the patterns of impulses as pain (Head, 1920; Lewis, 1942; Noordenboos, 1959). Essentially, pattern theories attempted to account for the complexity of the pain experience by referring to the encoding and de- coding of neural impulses. Despite the complexity of the theory, man in this model remained a passive recipient of the pain sensation. With both the pattern and the specificity theories, the psychology of experience was re- duced to the physiology of stimulation and transmission. Medical practice has long been based on these models. Treatment has attempted to relieve pain by eradicating the "painful" stimulus, either by treating directly the injured or diseased organ, or by blocking the transmission of sensation by means of analgesic medication. An example of ‘ the compelling power of such models in the interpretation of basic data has occurred in conjunction with the practice of administering morphine to persons suffering from severe pain. For decades it was assumed that morphine acted directly upon the neural capacity by inhibiting the 1? transmission of painful stimuli. Not until the late 1950's did Beecher (1959) conclusively demonstrate that morphine inhibited the subjective reaction related to anxiety about pain, and not the function of neural transmission. This and other research contributed to the growing recognition that, psychologically, man is not a passive but an active participant in the experience of pain. Anticipation of pain, anxiety and attention (Hill, 1952), cultural background (Chapman, Finesinger, Jones, and Cobb, 1947), early experience (Melzack, 1973) and prior condi- tioning (Pavlov, 1927) were all shown to have a profound effect on both pain experience and response. From a strictly phenomenological viewpoint, it would seem obvious that human beings play an active role in responding to pain. Common responses include the cognitive effort to identify the noxious stimulus, emotional reactions such as anguish or indifference, and the motivational response of fight or flight. On the other hand, basic evidence exists that man plays an active role not only in the response to pain but also in the perception of pain. Much of this evidence was incorporated by Melzack and Wall (1965) in their formulation of the Gate Control Theory of Pain. The Gate Control Theory of Pain proposed by Melzack and Wall (1965) provided a basis for considering the active role played by cognitive, affective, and motivational factors in the actual perception of pain. In so doing, it 18 made an important distinction between the perception of pain and the sensation of pain, by insisting that all per- ception is an active response to sensation. 'Sensation is an available "given," while the act of perception is interpretive, creative. The perception of pain, according to Melzack and Wall (1965), has three active dimensions, each of which is associated with a particular neural organization or system: Sensory-discriminative activity enables a person to locate the painful stimulus in time and space. The motivational-affective system relates to the responsiveness to noxious stimulation and to emotional input such as fear and anxiety. The cognitive-evaluative system has the capacity to act very rapidly in identifying, evaluating, and selectively modifying the sensory input; through this system past experience, disposition, and attention all exert their influence in evaluating the input as threaten- ing or not. This analysis of input rapidly interacts with the motivational-affective and sensory-discriminative functions to compare the stimulus with other input and with memory, and to bring into action response strategies. As a result, the cognitive-evaluative system has the capacity directly to modulate sensory input before it is transmitted to the sensory-discriminative and the motivational— affective systems. The temporal priority of this system is an important aspect of the Gate Control Theory, as it 19 implies that cognitive activity can intercept and either minimize or exaggerate sensory input before a person has an opportunity to make an affective/motivational response to the input as "painful." The probability that "higher central nervous system activity" plays a critical role in the perceived intensity, duration, and significance of pain, a position now firmly supported by experimental evidence (Wall, 1976), may justifiably be said to have been anticipated by the phenomenological movement in twentieth-century philosophy. The phenomenologists have insisted that all human percep- tion is determined by each individual's total disposition toward the object of perception. This disposition involves a set of cognitive, affective and conative functions sub- sumed in the concept of "intentionality" (Husserl, 1962), which may be characterized as an active orientation toward sensory experience. All perception is an act of not only focusing and identifying but also interpreting the nature of the world in individually relevant terms which reveal personal intent toward the objects of perception. Stated most simply, perception is an act of problem- solving (Gregory, 1970, cited in Brady, 1976) of active attempts to cope with life and find it meaningful. This concept of perception as active coping has been given expression in psychological terms by Sternbach (1968): 20 By "perceptual" is not meant a passive reception of stimuli, if indeed that ever occurs, but an active process of searching, discriminating, and distort- ing that reflects an adaptive, need- satisfying, motivated perception. By "coping" is meant the comparable pro- cess in overt behavior. We hyphenate perceptual-coping styles to point up the obvious interaction: coping is in part a function of perception, which in turn is a function of the same motives which underlie overt behavior. (p. 157) This conceptualization of perceptual-coping as an act of problem-solving adds vital dimensions to the study and treatment of human pain. Pain-as-an-answer-to-a-prob- lem-in-living becomes as important a concept as pain-as- response-to-a-noxious-stimulus.* What a patient says or does about his pain may no longer be viewed as mere sub- jective reactions to an objectively quantifiable pain stimulus, but must be appreciated as an integral feature of the pain itself (Fordyce, 1976b) so that stimulus, per- ception, and response are viewed as interrelated aspects of the entity-in-pain to be treated. As Merskey has noted: * To View pain as a consciously contrived attempt to solve problems in living is to assume far too simplistic a perspective. Merskey (1976) has also noted that the interaction between psyche and soma must lie beyond conscious control. It is actually rather difficult to imagine a pain, or even to recollect vividly the experience of severe pain. If patients have pain for psychological reasons, and many do, this must usually occur because of the operation of mental mechanisms that produce it independently of the patient's conscious wishes. (p. 711) 21 It is easier to honor the patient's ex- perience if we keep in mind that what- ever the physical basis for pain it can be known to an individual only through his consciousness. Thus pain is al- ways and only a psychological experience. (p. 712) Personality Inventories and Sufferers of Chronic Low Back Pain The measurement of personality characteristics associated with low back pain has most often been under- taken with the MMPI. MMPI profiles have been compared to discriminate between patients with physical findings (organic) versus without physical findings (functional), between sufferers of acute versus chronic low back pain, between back pain patients versus other orthopedic patients, between those receiving and those not receiving employment compensation, and between patients successful in treatment and those unsuccessful. Investigating clinical findings that many cases of chronic low back pain could not be related to physical deficits, Hanvik (1951) attempted to differentiate the MMPI profiles of back patients designated functional (no physical findings) versus organic (positive physical find- ings). His sample consisted of two groups of thirty veterans equated for age, socioeconomic class, marital status, and intelligence. The functional group's composite profile demonstrated a higher "neurotic triad," i.e., the Hypochrondriasis, Depression, and Hysteria scales of the 22 MMPI. Additionally, the Depression scale was significantly lower than the two adjacent scales, thus yielding a V- shaped profile known as the psychosomatic-V or "conversion- V," so called to indicate that patients with this profile are likely to repress or deny their emotions (high hysteria, low depression) and instead focus on somatic concerns (hypochondriasis). These functional patients have been described (Lachar, 1974) as having a strong need to inter- pret their circumstances in a logically and socially acceptable manner, and as resisting suggestions of any weak- ness or unconventionality in their character. In general they are described as egocentric, immature, and dependent. Their complaints of pain appear to allow them to avoid awareness of anxiety and conflict, albeit at considerable cost in emotional control and repression. The organic group's composite profile, by contrast, had non-significantly elevated and approximately equal standard scores (i.e., no conversion—V) on the scales of the neurotic triad, and the profile in its entirety was essentially normal. The functional group, in addition to the conversion-V, also recorded significant elevations on the Psychopathic Deviate, Psychasthenia, and Schizophrenia scales, further indicating the presence of psychological factors involved in these patient's experience of pain. Apparently Hanvik's (1951) results, suggesting con- version hysteria as an etiological factor in functional 23 low back pain, were of sufficient face validity as to generate little controversy. It was not until 1964 that another MMPI study of low back pain was reported, this time comparing 58 low back pain patients with a group of 72 patients with limb fractures (Phillips, 1964). As the low back patients in this study were not given functional/ organic diagnoses, it may be assumed that they repre- sented a mixed group in this respect. The profile of this mixed group of back patients had a significantly elevated neurotic triad, both above the mean and above the group with fractures; however, there was no evidence of a con- version-V. Such a profile indicates neurotic involvement with an existing physical condition, rather than a con- version of emotional conflict into physical symptoms al- though, from the perspective of Hanvik's (1951) earlier findings, it may be argued that this non-V composite pro- file was a direct result of Phillip's failure to discrim- inate between functional and organic conditions among his subjects. An additional noteworthy finding of Phillip's (1964) study was that the amount of neuroticism, as measured by the MMPI, was negatively correlated both with prompt completion of a rehabilitation program and with symptomatic improvement in the medical condition, in- dicating that affective and motivational variables may play a decisive role not only in task achievement but also in the chronicity of pain. 24 Further research utilizing the functional/organic dichotomy was undertaken by Haven and Cole (1972). Composite MMPI profiles revealed no significant differences among organic, functional, and malingering male veterans (N 44) with chronic low back pain. Gentry, Shows, and Thomas (1974) studied 56 male and female patients whose chronic low back pain had per- sisted despite at least one surgical intervention. Both males and females had significant elevations on the neurotic triad, with the males scoring slightly higher. This between-sex difference is consistent with the report of Sternbach et al. (1973a). Beals and Hickman (1972) studied 180 industrially injured patients treated in a physical rehabilitation center, and found that the group of back-injured patients evidenced an elevated neurotic triad on the MMPI, with acute patients tending to peak on the Depression scale and chronic patients tending toward a conversion-V. The chronic patients also had elevations on the Psychasthenia and Schizophrenia scales. In general Beals and Hickman found greater psycho- pathology in back-injured patients than in extremity- injured patients andichhronic, multiply-operated than in acute patients. In addition, patients with higher eleva- tions on the Hypochondriasis and Hysteria scales were less likely to return to work. In this study the chronic patients most closely resembled Hanvik's (1951) functional 25 group, indicating that chronicity of pain may have been a confounding variable in Hanvik's study. Recent studies by Sternbach and associates (1973a,b) have contradicted Hanvik's findings of MMPI differences between functional and organic patients. In a sample of 68 patients, 44 of whom had physical findings and 24 of whom did not, no significant group differences were found (Sternbach et a1., 1973b). The same researchers (1973a) reviewed the MMPI profiles of another sample of pain clinic patients, 81 with positive findings and 36 without. Again, no significant differences were found. In both studies the composite profile for all patients revealed neurotic triad elevations that were two standard devia- tions above normal, or higher than would be obtained by 96% of the normal population. There was no evidence of a conversion-V. The authors therefore discounted the diagnosis of conversion hysteria and gave preference to the diagnosis "psychophysiological reaction with depres- sion." They concluded that the organic/functional dichotomy is of questionable value in the evaluation and treatment of patients with chronic low back pain, and pointed out that once a patient's pain has passed from the acute to the chronic stage, and thus begun to dominate the patient's emotional and social life, chances are slight that the patient will get well, benefit from surgery, or success- fully adapt to permanent disability, without appropriate 26 intervention. Successful intervention dependtheavily on treating the depression and helping the patient to meet "those needs which, unmet, have resulted in excessive somatic concern and bodily pre-occupation" (1973b, p. 229). This concept of an adopted life-style based on pain has been supported by research (Sternbach et al., 1973b) into the differences between acute and chronic low back patients. Pain of more than six months' duration was defined as chronic, of less than six months, as acute. Acute patients had neurotic triad elevations one standard deviation above normal, chronic patients had neurotic triad elevations two standard deviations above normal. Additionally, acute patients had slightly higher eleva- tions on the Paranoia and Hypomania scales, indicating a greater sense of urgency and apprehension about their pain. In the transition from the acute to the chronic state, this anxiety evidently tends to be replaced by depression. Finally, in attempting to identify differences be- tween low back patients with compensation action pending (n = 36) and those with such action settled or never initiated (n = 81), Sternbach et al. (1973b) discovered that both groups had significant elevations on the neurotic triad, with the litigants significantly higher than the non-litigants. Also, the former group scored significantly higher (T-score = 70 vs. T-score = 61) on the PsychOpathic Deviate scale, which typically reflects anger, rebelliousness, 27 and resentment against authority figures. The authors suggested that this profile of "compensation neurosis" was inauspicious for improvement in condition, at least until the litigation was settled. While the majority of evidence supported Sternbach and his co-workers in their suggestion that all chronic low back pain patients had significant neurotic involve- ment, their findings that the MMPI did not significantly differentiate between functional and organic patients, as earlier indicated by Hanvik (1951), has in turn been con- tradicted by two more recent studies. Clinicians at the Seattle Veterans' Administration Hospital (Freeman, Calsyn, and Louks, 1976) classified 36 patients as either organic, functional, or "mixed" on the basis of physical findings, the "mixed" group comprising those patients who had some organic basis for their pain, but insufficient to explain the full degree of their reported pain. The patients were matched for age and educational level, 12 to a group. Each patient was administered the MMPI as part of a routine evaluation at admission. All three groups obtained composite profiles with significant elevation on the neurotic triad, but the organic group scored significantly lower on all three of the scales, and the functional group slightly higher than the mixed. The functional and mixed groups showed clear psychosomatic-V patterns, the organic group had none. Consistently, the Psychasthenia and 28 Schizophrenia scales were significantly elevated, but only for the mixed and functional groups. These results were clearly supportive of Hanvik's (1951) findings that the MMPI did in fact differentiate between low back patients with and without positive physical findings. However, these results also supported the conclusions of Sternbach et al. (1973b) that even patients with a clear organic basis for their reported pain were significantly neurot- ically reactive to their pain. Hanvik had found minimal or no neuroticism among organic patients in his sample. In a further study the Seattle authors (Calsyn, Louks, and Freeman, 1976) contrasted the MMPI profiles of 31 organic with 31 mixed patients. Virtually identical comparisons prevailed between these groups as on the pre- vious study. Again the conversion-V was present for the mixed but not for the organic group, with the organic group nevertheless evidencing a neurotic profile. Here, as before, the mixed group scored significantly higher on the Psychasthenia scale. Unlike the previous organic group the patients here classified as organic obtained a significant elevation on the Schizophrenia scale, as did the mixed group. It is important to ask why some research has deter- mined that the elevation and configuration of the MMPI- neurotic triad does differentiate functional from organic pain patients, while other research has not found this 29 result. Two possibilities should be considered. Swartz and Krupp (1971) have found that older medical patients tend to have elevations on the Hypochondriasis and Hysteria scales, and that these scales are therefore less useful in making a functional vs. organic diagnosis among older patients. The research of Sternbach et al. (1973b) con- cerned patients in their early forties while Hanvik (1951) did not report the ages of his patients. One might sus- pect that Sternbach's patients were older, based on the fact that Hanvik's sample consisted exclusively of veterans likely to have served in World War II, his research having been conducted shortly after the war (1949-1950). The average age of his subjects was likely to have been closer to 30 than to 40 years. The second reason for the contradictory evidence is likely to involve the criterion for evidence of positive physical findings. Hanvik's criterion - protruded intervertebral disc - was especially stringent, and was confirmed both by X-ray and upon re- moval of the disc at time of surgery. Sternbach's criterion included such manifest behavior as impairment in gait, reflexes, and range of movement, findings which some in- vestigators would consider to be of potentially psychogenic etiology, and not necessarily indicative of disc pathology. In summary, the majority of MMPI studies of chronic low back pain patients have provided evidence that such patients are neurotic. Elevations on the Hypochondriasis, 30 Depression, and Hysteria scales consistently are found in group profiles. These elevations tend to be greater among patients who have minimal or no detectable organic basis for their pain, indicating the possibility of psychosomatic pathologyf They are also likely to have an elevated score on the Psychasthenia and Paranoia scales, and occasionally on the Schizophrenia scale. It has been suggested by Sternbach et al. (1973b) that regardless of the extent of physical findings, chronic low back pain patients are likely to be neurotically involved with their pain, and that treat- ment of the neurosis is important for any recovery from or adjustment to back-related disability. Treatment Studies A smaller body of research has attempted to identify personality factors associated with outCome of treatment for chronic low back pain. In an analysis of the relation- ship between demographic, medical, and psychological factors and successful outcome in a rehabilitation program for patients with low back disabilities, Nagi, Burk, and Potter (1965) studied the case records of 125 admissions to the Ohio Rehabilitation Center. The outcome criteria consisted of achieved improvement in activities of work and daily living, as compared with the expectations of the clinical team. Psychological factors were measured by psychiatric ratings and unspecified psychological testing. 31 These researchers found that emotional and personal prob- lems were more prevalent among non-achievers, and concluded that emotional and motivational factors must be assessed and addressed in physical rehabilitation programs. Wilfling, Klonoff, and Kokan (1973) administered the MMPI to 26 male veterans who were to have spinal fusion for low back pain relief. Post-operatively (no indication is given of elapsed time), a success/failure rating of good, fair, or poor was assigned to each patient on the basis of a combined score for employment status, presence of pain, range of movement, the patient's rating of the value of surgery, and the thsician's rating of the degree of dis- ability. The three outcome groups were successfully dif- ferentiated by the MMPI: The poor and fair groups both had high elevations on Hypochondriasis, and both were significantly higher than the good group. Both the poor and fair groups scored high on the Depression scale, with the poor group nearly three, the fair group nearly two, and the good group less than one standard deviation(s) above normal. On the Hysteria scale, both fair and poor groups showed significant elevations. Additionally, the poor and fair groups scored significantly lower than the good group on the Ego Strength scale. MMPI comparisons were also reported for a grouping based on number of previous surgeries. The multiply - Operated group showed significant elevations on all three 32 scales of the neurotic triad, with Hysteria and Hypo- chondriasis scores significantly higher than the singly operated group. Also, no previously multiply-operated patient achieved a good outcome. These results were partially supported by another treatment outcome study conducted by Wolkind and Forrest (1972). The Middlesex Hospital Questionnaire, a self- rating measure of neurotic behavior and symptoms, was administered to 50 male patients prior to treatment for low back pain. After six sessions patients evaluated their own outcomes by means of another self-rating questionnaire. The good versus poor outcome groups showed significant dif- ferences on the depression, somatic concomitants of anxiety, and obsessionality scales, with the poor outcome group in each case scoring higher in the neurotic direction. Pheasant and Holt (1973) attempted to determine personality correlates of response to treatment for low back pain at an orthopedic hospital. An initial sample of 95 and a second, cross-validational sample of 94 patients were administered a battery of psychological tests and then assessed daily for response to treatment, the outcome criterion being improved functioning in the activities of daily living. In evaluating their data the authors found that poor response to treatment was positively correlated with neurotic symptomatology as interpreted from the MMPI. Support for this relationship, however, was minimal, and 33 another inventory of health concern, the Cornell Medical Index, provided non—confirmatory data. Blumetti and Modesti (1976) compared 42 patients' pre-treatment scores on the MMPI with the outcomes of their neurosurgical treatment for intractable back pain. The unsuccessful group, as determined by their report of non- significant relief of pain at six-month follow-up, scored significantly higher than the successful group (n = 19) on both the Hypochondriasis and Hysteria scales. Viewing these results together with patients' performance on the Rorschach, the authors concluded that those patients who responded favorably to neurosurgical intervention for chronic low back pain are relatively less pathologically pre-occupied with overall bodily concerns, less dependent, and more capable of a higher level of in- dividuation. They are also less rigid and constricted in terms of defense mechanisms and can rely on more than just somatic complaints to deal and interact effectively with the world around them. (p. 324) A similar study Of 34 consecutive admissions to a general hospital orthopedic surgery department was conducted by Waring et a1. (1976). Pre-treatment administration of the MMPI, however, was unable to uncover any differences between the poor and good outcome groups, which were deter- mined on the basis of physicians' post-operative ratings of operative success. The discrepancy between these and previous findings, suggested the authors, may have been a result of the small sample size. More likely, they believed, 34 it was due to the thorough pre-admission screening by the surgeon, who had excluded many patients with poor surgical prognoses. Those who had been excluded were most likely those with disproportionate neurotic involvement, i.e., precisely those who in other studies (Calsyn et a1., 1976; Freeman et a1., 1976) have been designated "functional" or "mixed" and who obtained significantly higher elevations on the neurotic scales of the MMPI and achieved poor treat- ment outcome (Wilfling et a1., 1973). Another treatment outcome study by Wiltse and Rocchio (1975) attempted to identify "good surgical risks." Their sample comprised 130 surgical candidates with low back pain, who had not had previous surgery but had also not achieved significant relief of pain from extensive conservative treatment. Prior to surgery each patient was interviewed and administered three psychological tests, the MMPI, the Cornell Medical Index, and the Quick Test of intelligence. The determination of surgical outcome was based on the surgeon's rating, one year after treatment, of improvement in physical condition and symptomatology. Analysis of data revealed that the single best predictor of the outcome criterion were the scores on the MMPI Hypo- chondriasis and Hysteria scales. Of patients with very low scores (54 and below), for example, 90% showed good or excellent improvement, while only 10% .30) with respect to the total sample population. The 24 items retained for the Back Treatment Success Scale, with the direction of item response endorsed most frequently by successful and un- successful subjects, is listed in Table 4.2. To test the potential usefulness of the 24-item scale in predicting outcome of treatment for a similar group of chronic low back pain patients, a cross-valida- tional procedure was conducted. This procedure involved computation of Back Treatment Success Scale scores for the 62 subjects whose MMPI records had not been included in the chi-square item-analysis. To compute individual scale scores, each scale item answered in the "failure" direction (i.e., the direction which had previously been endorsed by a greater percentage of unsuccessful than successful subjects) was scored 0; each scale item answered in the direction previously endorsed with greater relative frequence by successful subjects received a score of 1. By way of example, for Item 2 in Table 4.2 a subject received a score of l for a TRUE response, because this response had been endorsed relatively more often by 65 TABLE 4.2. Back Treatment Success Scale: Direction of Item Response Endorsed More Frequently by Successful vs. Unsuccessful Subjects (N = 185) MMPI Direction of Successful S's Direction of Unsuccessful S's Item Response % Endorsing Response % Endorsing 2 T 94.0 T 81.9 3 F 60.0 F 79.2 23 F 91.7 F 76.4 60 T 98.0 T 74.0 61 F 95.7 F 69.0 72 F 84.8 F 67.2 106 F 93.8 F 79.1 125 F 87.8 F 70.0 142 T 52.1 T 71.8 175 T 71.4 T 54.9 184 F 100.0 F 88.9 185 T 92.0 T 73.6 187 T 89.6 T 66.7 211 F 97.9 F 86.4 213 F 100.0 F 89.6 215 F 83.7 F 66.7 247 F 97.8 F 86.8 248 F 54.3 F 72.7 266 T 51.1 F 69.1 268 T 77.3 T 58.8 272 T 87.5 T 71.8 281 T 83.0 T 64.3 323 F 83.7 F 63.3 392 T 53.7 T 71.7 66 successful than by unsuccessful subjects. A proportional scale score for each subject was then obtained by summing the item scores (0's + 1's) and dividing the sum by the number of items to which the subject had responded. This procedure prevented items left blank from being scored as 0 or "failure." The resulting scale scores for each sub- ject therefore ranged from 0 to 1 at the hypothetical limits, with relatively higher scores indicative of success. I Mean scale scores were then computed for two sub- groups of the cross-validational subjects, one consisting of those subjects identified by the Pain Survey as successful (N = 26) and the other consisting of subjects likewise identified as unsuccessful (N = 36). The com- parison of mean scores is presented in Table 4.3. TABLE 4.3. Analysis of Variance of Back Treatment Success Scale Scores of 26 Successful and 36 Unsuccess- ful Subjects Source SS df MS F p Between Groups .0345 l .0345 2.90 .094 Within Groups .7143 60 .0119 Total .7489 61 The difference in mean scores was statistically significant at the .094 level. This comparison indicated some stability of the scale-items across groups, but the 67 significance level obtained did not warrant rejection of the null hypothesis. Re-Analysis of Data for Total Sample Population Despite the failure to reject the null hypothesis, the moderate level of significance achieved in the cross- validational procedure provided some evidence for the homogeneity of the total sample and for the stability of items included in the Back Treatment Success Scale. Consequently, it was decided to increase the statistical power of the chi-square computation by which scale items had been identified; the scale-development sample and the cross-validational sample were pooled in order to re-test the significance of items discriminating between success- ful and unsuccessful subjects. With the increased cell frequencies for the 2 x 2 chi-square analysis, it was assumed that significantly discriminating items would have greater stability, and would thus provide a more appropriate basis for the attempt to identify personality factors associated with success or failure in treatment. Recomputation of the chi-square analysis for all 185 subjects yielded 45 items significant at the .10 level. The MMPI scale categorization of these 45 items, with direction of response endorsed relatively more often by unsuccessful than successful subjects, is presented in Table 4.4. (Results of the chi-sqaure analysis for all 68 TABLE 4.4. Scale Categorization of Items Discriminating at .10 Level between 76 Successful and 109 Unsuccessful Back Clinic Patients (N = 185) Scales MMPI Diagnostic Validity Item Hs D Hy Pd Mf Pa Pt Sc Ma Si L F K 23 T T T T 46 60 F 61 T 69 T 82 F f 91 t t 95 104 T T 106 . T T 113 115 F F 131 F 134 F f f F 145 t 156 T T T 159 T T 185 F 186 T 187 f F 211 215 F 220 F 225 F 230 F 243 247 T 248 F F a . . . Lower case f or t denote responses not scored dev1ant for spec1f1c MMPI scale. 69 Table 4.4 (continued) Item Hs D Hy Pd Mf Pa Pt Sc Ma Si 249 F 251 T T 260 f 266 t t t 268 F t 272 F 278 T 282 t t 284 T T 292 F 295 t 323 T T 343 T 367 375 391 392 Total b 2 8 4 8 3 2 3 7 2 Does not include lower case responses. 70 399 items, with endorsement percentages of successful and unsuccessful subjects, are contained in Appendix C). Each of the ten diagnostic and three validity scales of the MMPI is represented by at least two of the 45 items, but the Depression and Psychopathic Deviate scales with 8 items each, the Schizophrenia scale with 7 items, and the F scale with 9, together account for nearly 60% of the item-scale categorizations. Surprisingly, 10 of the 45 items were endorsed with relatively greater frequency by the unsuccessful subjects in a direction which indicated no deviant response on any of the diagnostic or validity scales. This does not indicate that the majority of successful subjects had responded to these items in the opposite, deviant manner; but it does indicate that relatively more successful than unsuccessful subjects answered in the deviant direction with respect to established norms of a specific scale. This, in turn, does not preclude the possibility that unsuccessful subjects were in fact responding with greater relative frequency in the deviant direction with respect to the distinct nosological category here being investigated, namely, back treatment failure. An attempt was made to identify, by content analysis of the 45 items from the MMPI, clusters of items representative of personality characteristics common to the unsuccessful subjects. A variety of such item clusters 71 emerged: (1) denial of social non-conformity (items #60, 225, 243, 292, 391 and 392; (2) self-depreciation tending to guilt and paranoia (46, 61, 91, 104, 106, 159, 260, 278 and 284); (3) health complaints and disease phobia (23, 131, 185, 230); (4) impaired faculties of concentra- tion, coordination and awareness (156, 159, 186, 187, 251); (5) depressed affect and behavior (134, 211, 248, 266, 268, 272, 343); (6) repressed hostility and authority problems (82, 145, 375); and non-affirmation of funda- mentalist religious beliefs with non-regular church attendance (95, 115, 249). Significant single items in- cluded acknowledgement of strong attraction by members of the same sex (item 69) and of excessive use of alcohol (item 215). To determine whether and how these item-clusters contributed to typical MMPI response patterns of this sample of chronic low back pain patients, a statistical factor- analysis of all 45 items was conducted. The SPSS image factor program computed and retained all factors with eigenvalues greater than 1.0 and listed values for the loading of all items on each factor. With this program the number of factors is usually equal to one-half the number of variables in the set. It is assumed in each case that a number of these factors will be unamenable to interpretation, and will not be retained (Nie et a1., 1975). 72 Image factoring in the present case generated 30 factors with eigenvalues greater than or equal to 1.0. The first ten factors, with eigenvalues ranging from 9.82 to 3.25 and accounting for 58.5% of the variance, were examined for feasibility of interpretation. Subsequently, the first eight factors, with eigenvalues 9.82 - 3.60 and accounting for 51.1% of the variance, were retained for further interpretation. A complete tabulation of the loadings of individual items on each of the eight factors is presented in Appendix D. In interpreting each factor, between 10 and 16 items were considered. For each factor, interpreted items included all those with a loading greater than or approximately equal to one-half the absolute value of the highest weighted item. These items are arranged in eight tables (4.5.1 - 4.5.8) representing the eight factors, with items arrayed from top to bottom according to decreas- ing absolute value of loading, without regard to sign. Item responses are labeled T or F according to the direc- tion more frequently affirmed by unsuccessful than success- ful subjects. Loadings are designated "same" or "opposite" with respect to the response direction. Thus, in Table 4.5.1, item 251 had the highest loading on Factor 1, with an absolute value of .57. The response listed for this item is T, indicating that a higher percentage of un- successful than successful subjects responded TRUE to this 73 item. The loading of .57 is designated "same," to show that the direction of loading coincides with T in the Response column. Each opposite or same item-loading must also be interpreted in light of the entire response pattern repre- sented by the factor on which that item loads. That is, each factor represents the response pattern of a subset of either successful or unsuccessful subjects, whereby it is extremely unlikely that all items in a given pattern will have been endorsed in either the same or in the opposite direction as the Response-value. It is reason- able to assume, for example, that Factor 1 represents the largest subset of unsuccessful subjects because, first, this factor accounts for a higher percentage of the vari- ance than any other factor and, second, all but one of this factor's thirteen highest weighted itms is weighted in the same direction indicated under Response. However, in interpreting the opposite weighting of this one item (#282, Table 4.5.1), it is necessary to bear in mind that only a 53% majority of unsuccessful subjects (see Appendix C) responded FALSE to this item, leaving 47% of the unsuccessful subjects who responded in a direction opposite to "Response." For this reason loadings desig- nated "opposite" were frequently found on factors apparently representative of unsuccessful subjects. 74 Interpretation of factors with approximately equal numbers of same and opposite item-loadings is complicated by the fact that for all but 2 of the 45 items, a majority of both successful and unsuccessful subjects responded to a specific item in the same (T or F) direction (see Appendix C). Item 249, for example, discriminated between successful and unsuccessful subjects at the .05 level of Significance; to this item 63% of unsuccessful and 78% of successful subjects responded TRUE. Thus, where this item occurs in Factor 4 as the most highly weighted item (Table 4.5.4), and with an "opposite" loading, one cannot at first glance determine whether, in this factor, this particular item-loading is characteristic of successful or unsuccessful treatment outcome, or whether this factor as a whole profiles successful subjects. Interpreting the significance of individual items on a specific factor is further complicated by the fact that the factor as a whole comprises a response-set. Within this set any given item is therefore part of a configural whole, and must be considered as such with respect to its prognostic value. This phenomenon is con- sistent with traditional interpretation of item values on the clinical and validity scales of the MMPI, where for a number of items a FALSE response may signify deviance on a particular scale or scales, while a TRUE response connotes deviance on another scale. Similarly, within this context 75 of the test asta whole, a significant elevation on a particular scale connotes varying degrees and kinds of psychopathology, according to the presence or absence of other significantly elevated scales. An example of this ambiguity in the present research may be seen in the load- ing of item 248 (sometimes feel happy without reason) on both Factor 3 (manipulative) and Factor 4 (Reactive Depression), which are indicative of opposite treatment outcomes. A tentative attempt was made to identify each of the eight factors as representative of either successful or unsuccessful subjects, and to characterize the content of the factor. As mentioned above, each succeeding factor proved more difficult to interpret: Factor 1. Hypochondriasis (unsuccessful) Characteristics: 1. extreme self-alienation, poor awareness of self 2. poor health and coordination 3. conflicted family relation- ships 4. repressed hostility 5. attraction by same sex Factor 2. Organic (successful) Characteristics: 1. affirmation of fundamentalist religious beliefs with regular church attendance 2. belief in social order (law enforcement) 3. less rigid defense system and more realistic self-appraisal than Factor 1 4. more healthy family and social relationships based on give and take TABLE 4.5. 76 MMPI-Item Loadings on Factors Related to Successful/ Unsuccessful Treatment Outcome successful subjects. Table 4.5.1. Factor 1: Hypochondriasis Item Loadingb Content 251 same (.57) no recall of own actions 156 same (.53) blank spells 247 same (.49) jealousy of family members 104 same (.46) lack of concern for what happens to self 23 same (.38) attacks of nausea and vomiting 187 same (.38) hands not clumsy or awkward 230 same (.38) normal circulatory-respiratory activity 186 same (.38) poor hand coordination 282 oppos. (.37) occasionally feel hatred for family members 61 same (.36) have not lived right kind of life 278 same (.35) feel strangers look critically 145 same (.34) feel like picking fist fight 69 same (.33) attracted by same sex 106 same (.33) feel wrong, evil 284 same (.32) sure I'm being talked about aR = response endorsed by higher percentage of unsuccessful than b . . same or opp051te Wlth respect to R. 77 ‘Table 4.5.2. Factor 2: Organic Item R Loading Content 249 T oppos. (.54) believe there is Devil and Hell 278 T same (.46) feel strangers look critical 113 T same (.44) belief in law enforcement 115 F oppos. (.41) belief in life hereafter 134 F oppos. (.36) thoughts sometimes outrace speech 220 F oppos. (.31) loved my mother 91 T oppos. (.31) don't mind being made fun of 391 F oppos. (.29) remember playing sick 185 F oppos. (.28) can hear as well as most people 282 F oppos. (.28) occasionally feel hate for family member 82 F oppos. (.28) easily downed in arguments 225 F oppos. (.28) occasionally gossip a little 95 F oppos. (.27) regular church attendance Table 4.5.3. Factor 3: Manipulative Item R Loading Content 323 T same (.39) had peculiar, strange experiences 113 T same (.37) belief in law enforcement 392 T same (.36) talk to strangers in public places 215 T same (.35) excessive alcohol use 248 F oppos. (.32) sometimes happy with no reason 375 T same (.31) experts no better than I 82 F same (.29) easily downed in arguments 106 T oppos. (.29) often feel wrong or evil 134 F oppos. (.28) thoughts sometimes outrace speech 145 T same (.28) feel like picking fist fight 284 T same (.27) sure I'm being talked about 104 T oppos. (.27) don't care what happens to me 131 F same (.26) don't worry about diseases Table 4.5.4. Factor 4: Item R Loading 249 F oppos. (.44) 248 F oppos. (.40) 292 F same (.39) 367 T same (.33) 115 F oppos. (.32) 106 T same (.31) 113 T oppos. (.30) 46 F oppos. (.29) 392 T same (.24) 211 T same (.24) 95 F oppos. (.23) 272 F oppos. (.22) 61 T same (.22) 78 Reactive Depression Content believe Devil and Hell exist feel happy without reason don't speak till spoken to not unusually self-conscious belief in life hereafter feel wrong, evil belief in law enforcement trusts own judgement talk to strangers in public can sleep in day, not at night weekly church attendance sometimes full of energy haven't lived right life Table 4.5.5. Factor 5: Item 272 266 186 247 46 oppos. (.27) R Loading F F T T F 260 T same (.26) F F T T F oppos. (.43) oppos. (.37) oppos. (.28) same (.28) 268 230 215 69 220 oppos. (.25) oppos. (.25) oppos. (.24) same (.24) oppos. (.24) Familial Conflict Content sometimes full of energy very excited at least once a week poor hand coordination jealous of family member judgement better than ever slow learner in school excitement ends depression normal circulatory-respiratory activity excessive alcohol use attracted by same sex loved my mother Table 4.5.6. 79 Factor 6: Somatization Item R Loading Content 243 T same (.38) few or no pains 95 F oppos. (.36) regular church attendance 225 F same (.29) sometimes gossip a little 156 T same (.28) poor recall of own activity 23 T same (.28) attacks of nausea and vomiting 60 F oppos. (.26) don't read all editorials daily 343 T same (.23) stop and think before acting 106 T same (.21) feel wrong or evil 113 T same (.20) belief in law enforcement 104 T oppos. (.20) don't care what happens to me 367 T same (.20) not unusually self-conscious 247 T same (.18) jealousy of family member 248 F same (.18) sometimes feel happy - no reason 284 T .oppos. (.18) sure I'm being talked about 220 F same (.17) loved my mother Table 4.5.7. Factor 7: Hypochondriasis Item R Loading Content 131 F same (.36) no worry about catching disease 106 T same (.31) often feel wrong, evil 251 T oppos. (.30) blank spells 392 T same (.28) talk to strangers in public places 82 T same (.27) easily downed in argument 323 T same (.24) peculiar, strange experiences 343 T same (.24) stop and think before acting 156 T oppos. (.23) poor recall of own activity 95 F same (.20) regular church attendance 61 T same (.18) have not led right life 80 Table 4.5.8. Factor 8: General Neurotic Item R Loading Content 220 F oppos. (.34) loved my mother 46 F same (.26) judgement better than ever 134 T oppos. (.25) thoughts may outrace speech 145 T same (.25) at times feel like picking fight 23 T same (.24) attacks of nausea and vomiting 295 F same (.24) liked "Alice in wonderland" 104 T same (.21) don't care what happens to me 248 F same (.22) can feel happy without reason 325 F oppos. (.19) gossip a little 284 T oppos. (.16) sure I'm being talked about 159 T same (.15) can't understand so well what I read 272 F oppos. (.15) sometimes full of energy 282 F oppos. (.15) at times feel hatred for family member 81 Factor 3. Manipulative (unsuccessful) Characteristics: 1. 2. 3. 4. self viewed as in control, without guilt, aggressively mastering situations world viewed as hostile, threatening strange experiences, excessive alcohol use manic mood swings Factor 4. Reactive Depression (successful) Characteristics: 1. 2. 3. religious beliefs with regular church attendance self experienced as wrong, evil, guilty trust in own judgment and ability to interact Factor 5. Family Conflict(equivocal) Characteristics: 1. 2. 3. 4. ability to overcome depression non-acknowledgement of poor health or excessive alcohol use conflicted family relationships attraction by same sex Factor 6. Somatization (unsuccessful) Characteristics: 1. 2. 3. 4. 5. depression, poor recall, guilt regular church attendance denial of social non—conformity, denial of pain nausea, anxiety conflicted familial relationships, including maternal Factor 7. Hypochondriasis (unsuccessful) Characteristics: 1. 2. 3. 4. 5. disease phobia self-alienation, low self-esteem compulsive, good recall, no blank spells non-regular church attendance peculiar experiences 82 Factor 8. General Neurosis (unsuccessful) Characteristics: 1. love mother, hate some other family member 2. depression, repressed hostility 3. declining powers of judgement and comprehension 4. nausea, vomiting 5. disliked "Alice in Wonderland" Summary of Results The analyses presented in this chapter pertained to the major research hypothesis, which was as follows: Items on the MMPI do not differentiate to a statistically significant degree between patients who achieve success and patients who experience failure in multidisciplinary treatment for chronic low back pain. Significant findings relevant to this hypothesis included: 1. With a chi-square analysis of the MMPI-item responses of 123 former back pain patients, it was possible to identify only 28 items discriminating at the .10 level, 10 of which were significant at the .05 level. 2. The best 24 of these items were incorporated into a Back Treatment Success Scale, which did not have statis- tically significant predictive validity in a cross- validational procedure with an additional sample of 62 former back pain patients. 3. The cross-validational procedure, however, did indicate considerable similarity of response among successful versus unsuccessful subjects, respectively, of the research and cross-validational samples. These samples were pooled for further data analysis. 83 4. The statistical power of the chi-square item analysis was enhanced by this pooling of subjects. For the total 185 subjects, 18 items were significant at the .05 level and an additional 27 at the .10 level. 5. By examining the content of these 45 items, it was possible to identify several personality characteristics apparently related to outcome of treatment for chronic low back pain. 6. A statistical factor analysis confirmed the previous content analysis, and indicated the possibility of con- figural relationships among identified personality char- acteristics. The implications and limitations of these findings will be discussed in Chapter V. CHAPTER V DISCUSSION OF RESULTS Summary The past three decades have witnessed an accelerat- ing rate of recognition and investigation of the psycho- logical dimensions of pain. Most recently, these activ- ities have culminated in the establishment of multi- disciplinary clinics as an approach to treatment of per- sons suffering from chronic low back pain. In such clinics psychologists have assumed a major role on the treatment team, providing a variety of counseling, be- havioral management, and stress reduction and muscular relaxation techniques, all of which aim to cure by impacting upon cognitive, affective, and motivational variables associated with the personal experience of pain. Personality testing conducted in these and similar settings has repeatedly confirmed the presence of psychoneurotic disturbance among a majority of sufferers of chronic low back pain. Moreover, the preponderance of evidence gathered in such situations indicates that higher levels of pre-treatment psychoneurotic involvement are posi- tively correlated with unsuccessful treatment outcomes. 84 85 The MMPI consistently has detected such involvement and has therefore emerged as a preferred instrument in the evaluation of chronic low back pain patients. The primary intent of this study was to explore the feasibility of further refining the diagnostic power of the MMPI by developing a subscale of MMPI-items for use in predicting outcome of treatment for chronic low back pain. A scale facilitating the identification of patients with poor prognosis could provide a valuable diagnostic tool and also improve the matching of treatment resources and patient needs. In working toward this end, the first phase of research required the development of a measure to assess long-term treatment outcome. The Pain Survey was con- structed expressly for this purpose, then successfully piloted. According to their response to this ques- tionnaire, a total of 185 former pain clinic patients were assigned either successful or unsuccessful treatment outcome status. From this sample population, two-thirds of the subjects were randomly selected to comprise a scale-de- velopment subsample, and the remaining one-third became the cross-validational subsample. The former subjects' MMPI records were analyzed by chi-square to determine which items significantly discriminated between successful and unsuccessful subjects. The items thus identified 86 constituted a tentative Back Treatment Success Scale, whose ability to discriminate between successful and un- successful subjects in the cross-validational sample was then tested. This test proved statistically non-signifi- cant. It was determined, however, that the small size of the scale-development subsample was likely to have been a major factor in the non-significant outcome of the test. Therefore, to provide as comprehensive a basis as possible for future research, the two subsamples were pooled and the chi-square test of item-discrimination was applied to the total sample population. A total of 45 items, all those discriminating at the .05 and .10 levels, were examined for standard MMPI-scale membership, then categorized on the basis of content, and finally factor- analyzed. Discussion This section will discuss conclusions drawn from the results of the statistical analysis, and limitations of the study. A major conclusion tentatively drawn from this research is that the use of the MMPI in diagnosing and screening chronic low back pain patients may be consider- ably enhanced by an analysis of specific item responses. By means of traditional MMPI analysis based on interpre- tation of scale scores and their configural 87 interrelationships, previous research has established several guidelines for the prediction_of treatment out- come among such patients. Two investigative teams (Wilfling, Klonoff, and Kokan, 1973; Pheasant and Holt, 1973) found poor response to treatment to be positively correlated with significant elevations on all scales of the neurotic triad -- Hypochondriasis, Depression, and Hysteria. Two other teams (Wiltse and Rocchio, 1975; Blumetti and Modesti, 1976) identified the Hypochondriasis and Hysteria scales as so correlated.' Sternbach (1974) obtained similar findings, and also identified elevations on the Psychopathic Deviate, Psychasthenia, and Schizophrenia scales as important predictors for back pain patients with particular MMPI profiles. Partial corrobo- ration of these findings had previously been obtained by Wolkind and Forrest (1972) with the Middlesex Hospital Questionnaire; they found that poor outcome was positively correlated with neurotic scores on the depression, somatic concomitants of anxiety, and obsessionality scales. A direct comparison of these findings with the present results would require the computation of mean scale scores from the records of subjects participating in this study. However, since these subjects were not atypical of back pain patients participating in previous studies, the assumption can be made that mean MMPI scale scores for successful and unsuccessful subjects are essentially 88 equivalent for this and other studies. The more pertinent analysis has to deal with the content and factor loadings of the particular items selected as discriminating. It should be noted here that the two types of analysis (traditional scale configuration versus item analysis) complement one another, but are not directly comparable. For example, the fact that in the present study two items on the Hypochondriasis scale were sig- nificant discriminators does not mean that unsuccessful subjects as a group scored an average of 2 points (raw score) higher than successful subjects on this scale. The true difference in scale elevation would be a function of the differential in successful and unsuccessful subjects' percentage of endorsement of all items on this scale, not merely these discriminating at a pre-set level. A gen- erally valid rule of thumb, however, would indicate a positive correlation between mean elevation of a given scale and the number of significant items belonging to that scale. With this in mind, results of the item analysis do suggest both similarities and differences with respect to previous outcome studies -- similarities, insofar as numerous items from the Depression, Psychopathic Deviate and Schizophrenia scales proved to be significant pre- dictors, and differences insofar as numerous items from the F scale proved significant. Why this particular 89 difference should exist is at least partially explicable by referring to previous publications concerning the F -scale. This is a validity scale monitoring test-taking attitude, and high scores on this scale may indicate either a deliberately distorted self-description which claims fictitious mental symptoms in the attempt to escape responsibilities or "an exaggeration of existing dif- ficulties to gain attention and assistance" (Lachar, 1974, p. 2). These interpretations can be reasonably discounted among chronic pain patients, the great majority of whom are notorious for their denial of psychological problems. Attention must therefore be directed to Blumberg's (1967) finding that the degree of F scale elevation is a good indicator of the severity of psychiatric disturbance. Where this finding applies, according to Lachar (1974), the testee is likely to be extremely self-deprecatory and suffering from severe stress. This appears to be the best interpretation of the data obtained here, as these are often-documented elements of the typical pain-patient pro- file. However, since no previous research has cited the F scale as a clinical predictor for this population, further interpretation of this finding should await in- dependent confirmation by future research. Another apparent anomaly in the present findings is the relative paucity of discriminating items belonging to the Hypochondriasis (two items) and Hysteria (four 90 items) scales. In fact, the two items belonging to the first scale also comprise two of the four items on the second. This appears contradictory to previous findings that high elevations on these scales are the most sig- nificant and consistent predictors of poor treatment out- come. Assuming that results of the current research are valid and that they are congruent with previous findings, the only possible explanation is that, even though a con- siderable number of items on these scales may have been endorsed more frequently by unsuccessful than successful subjects, thus yielding higher mean scores for unsuccessful subjects, for only a very few items did difference in rate of endorsement reach statistical significance. This explanation is completely plausible and, as stated above, simply illustrates that scale analysis and item analysis provide complementary results. In this respect suggestions by Sternbach (1974) regarding a more refined approach to configural interpre- tation are worthy of some attention. He suggested that analysis of personality differences between successful and unsuccessful subjects could best proceed from an ex- amination of four MMPI profiles frequently obtained by low back patients, which he designated as typical of hypo- chondriasis, reactive depression, somatization, and manipulative reaction. These four profiles were reviewed at length in Chapter III. They are