"Transcriptional repressors control temporal and spatial patterns of gene expression in animal development through co-repressors, which interact with histone modifying enzymes and chromatin remodelers. In this work, I used genome-wide approaches to understand the mechanisms of repressors and corepressors by identifying biochemical changes on chromatin using the Drosophila Hairy long-range transcriptional repressor protein as a paradigm." -- Abstract.
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