"Life at the nanoscale creates a dazzling array machines and structures. Studying these nanoscale creations often requires inter-disciplinary efforts of scientists, along with the support of other personnel. This thesis serves to communicate some personal insights and data captured in studying nanoscale organization of biologically-driven components, as part of such a team. The first chapter addresses spatiotemporal organization of material inside cells, with a focus on scaffolding-type strategies. The second chapter offers a literature perspective on constructing scaffolds with a structurally-characterized protein-domain. The third chapter surveyed functionality of an in vivo designer nanoscaffolding system. The fourth chapter, alongside the appendix materials, forms a collection of future-steps and comments on projects I have encountered while working on my thesis project."--Page ii.
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