"Nitrogen containing compounds, such as amines, imines, enamines and a variety of heterocycles are incredibly valuable. These compounds are prevalent in many pharmaceuticals, organic dyes, solar cells, and natural products. Therefore, new synthetic routes into these nitrogen containing compounds is highly desirable. Our group has been exploring a titanium-catalyzed multicomponent coupling reaction to synthesize a wide variety of nitrogen containing compounds (Chapter 1). Using these titanium-based catalysts, our group has developed a variety of substituted quinolines, which have been shown to be novel proteasome inhibitors (Chapter 2). Our group has also developed a new tool to help evaluate ligand donation, which has allowed us to expand and develop a better understanding of the titanium-based catalysts (Chapters 3 & 4)."--Page ii.
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