Suppression of interleukin-2 secretion by 15 deoxy-prostaglandin J2-glycerol, a putative cyclooxygenase-2 metabolite of 2-arachidonyl glycerol, involves the activation of peroxisome proliferator activated receptor gamma

"The overall goal of this project was to determine the mechanism of IL-2 suppression by 2-AG by testing the following hypothesis: 15d-PGJ2-G, a putative COX- 2 metabolite of 2-AG, suppresses IL-2 secretion, in part, by the activation of PPAR! and involves modulation of nuclear factor of activated T cells (NFAT) activity."--From abstract.