_. ..-. JzflWeI-Cfi‘: .9,

 

 

 

 

mum or DEPRAVED APPETITE INUAIRY CATTLE“ ‘  
THESIS FOR DEGREE as: MS, -
GEORGE‘E-Q‘TAYLGR .

192,5

 

 

 

 

 

¥

LMU

UBRARY
ichigan Stat
niversity

97

fl

 

PLACE IN RETURN BOX to remove this checkout from your record.
TO AVOID FINES return on or before date due.
MAY BE RECALLED with earlier due date if requested.

 

DATE DUE DATE DUE DATE DUE

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

5/08 K:lProj/Acc&Pres/CIRC/DaieDue indd

 

 

c"
s

.u,.

-
... \p‘a

W.
y

" "tr-'33
;~.¢o.\ on. 4‘

~}

i

11"

"57’
-.04.J- and,

Ill LTLIEY C;".';:....'f:,".

:» v4

‘H-A

, ‘von ‘ w v... , o .. _ ~ - -
{a . I”: v I? ) $ $* ) 7‘.) 5. "T'E'. Ia: 1‘;
A o-\.l.’ah '4' ‘ ‘ ‘ “I. DJ .)..- , I 4 .. -__44 .. *—

In:
fl

‘ C'!\ 71“."
..- 53(- .44.;

tubalttod to the faculty of tho 31-2152n Etate College
in partial fullnont of. the r0.111rc..“1(211t8 for tii: dogiroo

of’Hueter of Science.

by
Games 3. Taylor

1935

.‘ V1”! . u, __.‘ I ?.r,“\
. t - ‘ ,- ,
u ups»: 75.4...‘-t..,...c_1.a

The author wishes to acnnozlcdge his indebtedness

to C. F. Enfimcn, Eccecrch Assistant in Dairy fiucbcndry,
coco help in planning and conducting the experimental
work, and kindly criticicne of th manuscriot have aided
materirlly in the writing of :hie thcie.

He also niches to expreee his eratltide to ProfLELOI
0. E. fioed, Road of the Dairy Department :0: his timely
advice and cesictence in this work.

Likewise the author niches to acan011edgo Lia
angrecintlon for the help given him by Eoctor C. E.
Hoblueon. Jeecarch Associate in Chcgietry and Doctor A. 3.
?attofl. Heca of the Chomictry fixycrimcnt #tafiion tho undo
the chemical dtterninetlone possible.

The writer also a graciutoe the aid fchn him.by
Doctor u. T. Hallmun. Associate ?rofceror of’Aninxl
?at clog: who performed the cutopey of eni;rle need on

this experia-nt.

1F—

IHIRJDUCIIJH
O SCRLL DISCUT”1§§ {fig REVILK Jfi LIIHSATJ¢S
I Definition and Discuseion
II Depravcd or ébnornal Apfietite
IFI Réiated Diseases
A Lanziekte
B 083003218018
0 Osceoue Cuchoxia
D Bush fichneSB
E Sweeney or Creoying Ficknoee
F Catton food Ecol 9oiconing
IV Causes of Sopravod appetite
A Calcium Deficiency
B ?hoeghoroue Eciicicncy
C Iron .-.seficiency
D .T’rotcin #eficiency
B Digcetive L Sturbcncca
V ?revention end Cure for Bogravod Apgetite
Y Summary of Review of Literature
2&7J£-;4J;53 .JHK
I Object of;3xporiucnt
11 31cm of experiment
III Hothod of ?rocedure
A Choice of Aninale
3 Choice of Feeds

0 Proyrrction oi Feeds

(5

3 Care. Shelter and Feudiug Eethode

1"
u

Collection of Experiusntol Late

(1)
(2)
(3)
(a)
(5)
(6)
(’7)
(t3)
(9)

weighing
measurcconta

Record of Food
Health Observations

Photographs

Collection of Blood Lcal-glee

Hetebolicua

autopsy of Animals

Farm Conditions of repraved Apgctite

17' Bxyurimeutcl Beta

1?.

Crlf
(1)
Calf
(1)
Gulf
(1)
Cali
(1)
Cali
(1)

0-13
Eaton and Observations
0-14
notes and Obtcrvationa
0-15
Hotoa and Observations
6-16
Notes and Observations
0-17

Hotee and Observations

Calves 0-10. 0-19. c-ao and

Cali
{1}
Cali
(1)

u~32
Dates and Observations
6-33

flotce and Observation.

0-31

45

 

 

I Calf 0-34
(1) flotee and ObeGrVations
J Calf 0-235
(1) Katee and obeorvationa
K Chi! 5-37
(1) fiance and ObseIVQtione
L Oil! 0-38
(1) Renee and Obeervatione
M Golf 9-50
(1) notes and Observationa
H Crlf 3-34
(1) 30308 and Obeorvctiona
0 Cali 0-36
(1) 30308 and Obcervctione
P CHIVCS 8-55. 0-37. 0-38 cnfi 0-39
(1) Hotoa and Observatioua
field Calves 1. 3. 5 and 4
R Dopravod eppetite under Farm Congitiane
C ficculte of aetuboliea Experiment

(1) 28b10_fi00 I
[2’ Eable £0. 11
(3) Table Eco III

(4) Table 30. IV

V' Diecneeion of uxpcrimcntcl Roealta 91
fl Exnerinental DeprnVCd Appetite 91

B Depravcd anctite in the Field 9§
coxcsjri,xs 97
31331034.- I 99

II
III

lOE-a
104
35

114

"""3"“.'-"° 'brfi?!\_.
Li ix .t..)éJU LA4L'11

Appetite ie not always a reliable guide to iroger
eniaal.nutrition. Dciry cattle roiuently Show a merged
appetite for things not ordinerily cleared as $006, euch
as dirt. rage. wood, bones. etc. aside from interfering
with.the prayer phyeioIOgicxl finctiOLing of the enimrl
body. the con804utucee resulting iron'the eetini of such
foreign meteriCI are sometimes Very serious.

The true economical importance of degraved appetite
may be estimated when we stop to reclice the financial
loge resulting from euch a practice. Cows in milk that
are affiliated with the dieeeee suffer a greet reduction
in milk flee. thilo ;o:n3 end graying enLnrle undergo a
marked cueertion in growth and become emaciated to the
extent that the: are rendered precticrlly voiceless from
the standpoint of future milk production.

This diocese is common throughout the united Ltetec.
end is found to unite an epfirocieble extent in the state
Of‘“i¢higrn. Farmers are prone to minimize the importance
of this cilment due to the fact that it does nut hove e

'well-deiined morbid entity. and tLe eymgtone are not orn-

 

ifccted in the nature of an acute febrile, contageoua or
communicable disease.

Ita importance may EIEO b0 ethesized from on ex-
pert-rental atrztzt‘igoint. animals! on various experiztzz- rite].
projects at the love, “i 'higon end mumsByivmtia experiment

. s ‘ 3" fl. -_‘ i o 4., w _L__ _._
titetionc have been atricrten 1. is.“ warms-nine ,—

extent that it interferes wits tne croscr interpretation

of exocrine: tel flete.
The cause and prev-en"; .1 on

definitely known. re nrfileec of

remedies and theories regarding
are 0 ton exeaunded. Q"
planned enfi conducted
on the :mderlying causes

yrevcntetive agente £8 a

in an eifort to

means of combating

of this emulsion is not
the ti.et various
the unture of ite onset

has been

three more light

and to determine the Vrluo of

thifi diECFEGo

I

- mg. ‘——-

C.'.;;;:;{..‘.L 315251;.‘71‘135 J": Z’:.;‘\II;'£;-,4 :3; 11.95.5333:
Depreved appetite is a dieeece that is conprretively
common among all cleeeee of ’iveeteck including deity cattle.
the disease occurs in all certs of th world and is feund to
come extent in Liichigen. being the meet qron'n need in the
theme region. Depreved e getite is also var; arricd among
experimental animals at the Hichlgnn Larisalturvl College,
particulerily enimcle reieed on restricted retiane; or HuiL£1£tl

on *ieta restricted in the amounts and Kinds of reintege.

pefinitien and Biecuesl:n

 

 

 

Depreved. or perverted appetite is defined by Lorlend \
(1) in his medical dicsicnery ee tLe longing for unnaturrl
end indigestible thinge 28 articles of food. Lepreved epyetite 1
13 common in r11 cleeeee of Livestock end dogceticeted eni ale. I
TLie disturbance ie genifeeted in different msuncre in the i
different cleerce of eniuele. Bone chewing. euntined with
wood chewing end dirt eating in cattle; pig eating in acne;
feetter ectinb in poultry and toe picning in chichene; noel
eating in 83609 and geese; wood chewing end cribbing in horses.
and copra 4833 (the outing of dung) of wild animals in ceethh
it: are some of the most noticeable outhzsrd mnifeetetione of
the dietureence. mature animals eufloring from depraved
appetite. perticglrrly cave in milk, Buffer 3 reduction in
m.lk flow. ceete become raggh35nd it eif.icted ier poniidereble
period 01 time develop a general run down and emaciated condi-

tien. YOung end growing enimele evidence fine same genernl run -

down.condition cue else suffer a ceeuetiwn in growth. In
addition.to tale general unthrifty'condition the resistance
of the anlmml 18 lowered gnu pathoaunic organirne, which
under oréinery conditions vault not be able to seine foot-
hold. are able to establieh thouselves enfl set up en in-

fectiin, which may result in the éeeth of tLe Buiuul.

P313124 9.; ilbfl’lrl’i jggietite

Outbreeua of depraved appetite are characterized by
regiinel end ceexonehle outbrerke ee recorted by Lclch (2)
of the University of fientena fiXperimcnt Ltetion. Bone chow-
ing by cattle has become much more conaon inlbntcue since
the closure of the "Open" or "Free Range", tine restricting
the grazing execs :0 that th cattle are new largely ceniiucd
to certain special types of sail tad forage. The ereee etere
the dcprerea appetite are the more common are tee regions of
poorer Belle. fhe confiitiin ea observed by Eclcn occurs 0513
where 'te cattle are fed on “mild H:y".groun largely on low :
lands, and consisting mainly of red tog, wire grace, blue !
Joint grace and various swamp grascec.

Yhe tine of’yeer the disturbance is *ie goat noticeable
varies. In some localities the cattle seem to be all right
in the fall but begin to once bones in the late rinter end
coring. In other inetencae the bone eating habit ie prvccnt
throu gout the anti 0 year. but becomes more aggravated in
the spring. However. some cattlemen re art the bone cloning
practice only in the fell months. Bone chweing by cattle in

Hentena is nothing new, and as long ago as 1910 numerous cases

were re arted b3 breeders, ens investigated b3 the fientnna

Experiment Ltetim. In recent 30ere the tremble is more
prev:lent, pertinulerly where the better class ef lane is
reserved for farming ;:3r;aecee. nine 1i: siting the {grezi ng
lend to areas of poorer e 118. Bone chewing is 8120 more
common during same 3eere tlen steers. This 3L3 be nertly
explained b3 the fact that the chemical coayesltien ol
forage plente le éetermlued b3 the hind of pleats end the
comicaltlen of the 8111 agon which they grow; that 18. if
the e3;1 1e acid at near, ahen it couueine little or no
11 c. ende roue gr3wn uJOH it will be low in lime. 3n tho
other {and in a very dry year 8) 18 that cents in plenty of
1130 neg produce greeeee “it b e ver3 low mineral content.
due to insufficient maiature to form a salubion of the coil
c oust i tuenta .

The general e3uptome of "bone chewing" cattle ea dee-
cribed by gulch, are these of a general run down UOhGltlin

and eaecie::3n. animals in the herds cgew hence just

occee‘flieu:113 and only a few deleope the habit. or 3 large name.

in tLe herd ms3 become pereietent bane eteecre. xrny "bone
chewing” cattle become shin, ati f. unpereutly feet core.
lune, end dielucllned to move abext; and although they eat

33:0 than ordiner3 cattle they louse 62633113 in condition.

The OQIVGB are light bones. oiten week, and tnere are 11:01}
to be mare ebortloue in the spring tLen are be acc3unted for

by the uenzl ceases. vntll spring 18 well advanced the cattle

are endleealy hunting forsoaethlng to eaniefy their craving.

cncwlng reels, boards. end bones. xeny cattle are lost each

1'

 

4

year 1101;! I: LO$L1-.' o: 1 Lone irei; :.}2‘21‘.$::, 211:1 3.3L)" cattlcmcn Lure
folnc it necessary, at Linea, to catch a cow and forcibly to-
move a bone fregeeut the: Led been wedged between the fives.
2cl~h pu liched the phctegrzphe 3f execs ecctiane e! the
femur end fibie of a cow grazed on vile grace, the: chered
hence ecceezen13. but ofiLerviee was in £51113 good canal tien.
"hose were eempnred with tLe femur ana fible of e cow ares ed
on alfelze Lecture. t; 3 red ev demoed no depre ity f In etine.
TLe Lance of tLe cow easiering from deprereé er etlte CLOLGG a
thin Lo: 13 well aleng the cleft of the bones. {the bony well did
net ex end amend t2e cnde of the bones. ennui}. over the
jelnt surfaces. The hence. tngcn cc 3 whole, WLre frail cem-
pered to the bones of the one grazed on alfalfe.' Thle finuld
tend to e31.)lxin :Le reason for co much lameneee, ctiffneee of
gait. and ezc.. in bone cLewing uttle. becauee tLere 18 no
sup orting well over the Joint surfaces. and hardl3 ennlgh
eup¢erting trength in.*he necae of tie hence to carry the
Lady weight.

Dcpreved enee Lite deee not occur under tLe eeme LoniiLikna
in young and mature animals. according to Lezecu end Bolier
(3). In eczlte it of gen resultc item fm alty fe.ding. er frem
some wasting disease which fleVGlepe ineiciocslg. or remains
unrecognized. The an‘; nnl hee certain c>ecial Le‘3 refihircucute
to meet. thcL must be eetiefied b; food of suitable cemgoa t’un.
If these alimentcrg end digeetlve re ulrcm:nta ere not anti flee.
dcfirevad epfetite may occur in enlmele thick appear to be well

nocrlchcd.

I

The 33233333 32 th dirwuzo are 3232333 inzn twa pLsrua
b3 Hnuafiu find floller. In tkn £1333 erFc LE3 nuiflrle 6:111
2032:2222 $229!! up 122.1" 2.0. but. 32:2222'222331 22222733 3222.0 122 02 203-2212222233
the: cat dirt. send. manure. liter unauretud 22 L art 220. plaster.
etc. The? link Lhu 3021a, the boxrfl'na, a $5638. 323 trnaa,
and 3133 chew 3333 rad trees: nnfi 33;: 3133 est aaLLu, e;=rt2clce
of clothing. or anything to whisk they 333 LLVO read: ancesa.
Zhia pLaaa H23 continua far a 1033 3233, tLLee to £32r mnnzhe
or 32ru. 3r3v1uing no Lento 33331203L13H3 :6 31% from tLe eating
of each foreign natcrlfll. mneru is n3 fever. but the appetita.
31 uhfiigh well mvhmrr"ou. 13 Gite” CLIILL 1223. Pa: LLL urgintry
fond 13 33333 313313.

In 1:37:22 8232:3219; 32122322, 22222222 122 in 22222. 17.1.; mark; 21 22;“ the
devalnpmunt 3f 03321163L2233 32233865 by the naeenge. contact.
at nr3133333 enjourn o: verinua 33tcr2rl in aha 325333130 crsct,
faver appuvra, uLuallg 11t213 332L3d re a rule. but 3132133228
in character. @Le normfilr £323 ite is £180 Giniuiihed. The

3312"1 3 art a wveting awry; gestation of 22212 3232312233; 22*Le

5.“

31 03 H31 3 gnfitrxucnfiarlfiie 3L3 be unteé; LLe 32YV2reia “ of

*5

333ez2t3 c n2t2 M23: and all mfinnur of 13315? 3 L10 matcrirl is
32uruaed. It 19 n3: Lurflrlning £333 each 82L813 one eat up an
12:?122:22:222231322 {11" 3218 222222032? #:2222221’2-22263 of 2.2222 22132223312222 track.
the 333313; pracecu £13313 lenda to euaoimtion. $33 after an
interval of tram 923 marahe to a 308?. 3r even $33 ynfrt. the
patienta din in u agate 3f 33331320 exhauczi33. The leninne
ia'md 022 3323?. 22:21-22:33) 62-22::1'2213'21322 are. 2212380 of marina—:2 222.52' 2.2232,
Ofipflnlo of r332 133 fiG:I“VGfl figpfitite. or (14313 loclnnr 03

ohrauio guafir3—L32351325.

In young Lgianla in is 3:1: ‘lw the r 3313 of incaffin-ant
nutriti3u. hesrnvad 33 aetita camara most Ira ..:Ltls' in calves
find lambs that are inaufiluisuzlj nauriuLad. or Wmflu the
m3thcra are nafiaring ‘ran chr3nic debilitating diflnfitfifi, and
as a resulz are yiclwlizg m 1L :3903 in jet an minerfil con~
etituants. 2L0 u.‘11voe oat nL: licL 8L9 Lrir from their awn
bodice and frnm the hadiae of other anlvca in th hard. then
thia heir enters the atansch it 13 mLLed with ”1031.. tnfi fihen
by the churnl.1g matiorz af the ruzwn 1e 13'13 532336 into
oegagraghilfis 3r Lair bells. TL3ee Lee. J tncreauing in size
33 "are hair is 32333 into the st3maeh. and {129113 refich a
8130 sufficient :3 Gauge an obstruction of tLe {:3loruc. The
gamma calves tzcn ra¢uea all unuriahncn, n31 die within a
phriod of tment3~ ~faur £3 for‘; 3-olwht lurure in a state 01 033‘
pleto cxhuuetiou.

In lambs the 0033110331358 due to fic3ravod 5333: to da~
Val3p‘in n eimiliflr mtnncr. ”ho 3031 rm:113:nd b3 1-:3b8, how-
ever. 13 usarlly obtainna from the fleece of their mozhuru.
Thu wool, unline hr r, is nu: easily £33336 into oeaxgrbrLilee;
nevertheless, it anon necniulntce in the fiylaric reg'nn. thus
oeuLLng an obetraoninn. Bovth than reuglta irna intestinal
abet r19 1:3n 0 ac 13 as 1n the ccae of cwlvce.

A. J. murray (4} at tee tht cat 19 sat: axing from de-
prnved agyetite have a capricioue :nd variable appetite as
regnrae their nrdlxnry foods, but 0 163303 a strong dueire :3

let an& ant eubetanuae 13: which hcrfl.::" cattle tLow no 1n~

‘0

clinazfa 3n. LlLallna anfl 621133 tasting eatatnncca era fifififiuirllg

attractiv9. 299“ , ill 1: ch 1139. 99939. curl, fir9VC1. 9nd
91:91: the 19999 91’ 292222912 0.922.219. Cm 9 in c:- 11‘ 2.921 529212 9223292218

scam $9 ha $99 9993 ,9909.t’919. F909 trL19le 699919; a 9109
3.9.3. 22.22.21 9.2.29.1}. 929919199 :99. ‘3221221 1;; 3911029117221 121‘ "2 fart: mfier
:99 tangue. The 9119. given by 993990 9919919, 9199 9999399
thin 99: 993923. Chg 9919919 become restless an: 9999 93 98
'ndioatnd by fr9_ueut bellowing. The 9199990 mny linger on
cnfi 19 98 for m>-st 2.9, 990 9919919 finally flying after 93991990

29919 inn 999 xh999319n.
"29: 09999 of degrnvad 99999199 are 91399 where 911 919999:

{239'

of 99119‘9 99 9911 99 999999 have n9vourea 911 mamxer of sub-

A.»
9999999 that 999 mat be rcgrracd 99 £016. fiacnra (6) reports
instances of aevvavea 992991 9 in hnr9A . 096 919, 99999. and
99:9. Kn: 999. 9.9999, wire. mint. 9899193. 99119. plfictor. 999.

|
Ernfi. 9999, 991! 999 9001 are mentioned 98 9099 of 990 cub- 1
9399999 99 ten. £9 999999 the: ha 993 runavca a pi1199 {firm

tram the 2‘W2.-9n of 9 c::3.f.:tnd.9 291$ h91.1 fran tI29 9n911 1991,9922

a

of 9 532293393? {19.3. ..'.1%1‘O 9 191330 331909 0... 0?;1‘60‘ ‘3 $3911 filo tame-n

9" 9 09:22. 72221;) 91 9 are 993.9 13-9 (29293793) ELI I: 22:92.19 for 999322

,. a I "r ' 5- "L
t 3.99.2.9 to {.9322 9 99:29., 2.9.2.2299“

:1
C}
I“:
0-
f3
3!
; '2‘.
H
at
23
s”
I. A.

Butler (6) r9 arts 09999 of 291:9 992233 dirt 999 faces.
0399 chowinn 999 rating 019 rage, 9999p 999 goats 9999193 and
eating the 9391 from 9999 oshcr's b;.i 9. 9:H.CL209299 pitting
rnd 992193 feathqra frag 99-3.: 922 999199 999 tram the 99929
of nthfir new bars of 399 $1099.

Heinz ask (7) 99:90: thee sze condition 9f oribhitera 9nd

9199 suckur9 in hora99. which 19 2? .‘mrrl 1y 9 69939999 99 99199.

Animals afflictud an 20 fine manger or Lnyaulug Lhuy cxn grnsp
between thuir tuotn and make a awund as if Suafiiflg 51:.

Law (a) likewise mentione the ucual eyrytone of dayyeved
epzetite in L1 :,=ae ezd cove unu cites instances Lhezo thy

have eaten wand, aartZA. manure an; Lance.

Lynch (9) brings 04L the Ike: that deprsved npyetito aflnng

amine 1e cannon. I: 18 donatimue Bean as a Eymgtom in other
dieenaoa. each 39 gastritis. chronic indigestion. and even Ln
hog chclnrn. capacisl ly in the chrzn;o tyye. It 15 alxo

‘C

connauly sum; macro hogfi fire fed inaae: ugto tunic.“ ospccixlly
one that is deficient in aluulina an” ea c: earthe. hogs

suffering fr 3 3218 trwable will larva goafl tholecsmc food un-

towimd in the at!) 1gb... and eat indigestiblo cubetmzcee 12.8

ea 3h. firicfi fcuen. irt and Rand. In e&Citian to losing fleeh

and becnuina Week and unthriity. the uuiaale are Irc‘auntly
quite na vans. uneasy and quarruleoma. tad may attack £ach
ofikar, oocsfiiauly a1131ng anfi eating one of thu mcfibcre of
the hard. Kama suffaring from this disease filao est stair

own pigs. Syuuh paints ox: ‘hafi detrrved apxcti 90 13 a flu »ger
Signal. wnrniuc tar: thu digestive trscx is fldt of orfier. and

it is 'wnortrut to race bar th3 thifi lutvca the hrra sptn to

attacga fhog c.013ru ad ache: diseases.
Baker (10} gnlute ext taut dapruved auswetito 18 commonly

seen in pregnant once. ha royerafi weal eating in wheep mar.

of a habit than a dieenau, than aucep no mire when the: are
penned up in close Qurrterfi.

according to Fox (11) copr Hang? (on Lna of nuns) ia not

infrequeut in Our 0 ptivu Lila animals. mud 12 ekfiecl:lly
natioeoLlo in the chingnnaee. fie atntse that the eating
of faces 19 not huslthf: , and probably flags nut occur in
nature.

It has boon previously pointed out In tfia warn that de~
preved appetite is cannon in hutzne. Ln adicwrifil in the

139.3310.

6

Lancet (1a) utetau that n Frexohann, Buffering from
logical aluttouy. devoured one-fourth a: a ban! in twenty-

four hnura. At times he also nausea eerpcnta and cute. con-
suming them hair an& all. Ehla men wag the dusuenéunb of a
temily that were earth estate, wood caters an; intact enterfi.

In m stimr article tn the Lancet (113) a French 3119011er in
anglund is rugortud as having the habit of eating rate. case

3‘ flags. at times dovaarina their entire basics. Curtain
triboe of natives 1n Fouth America are 851; to be earth enters.
and often £111 nhelr afiouenhs with lrrgn Wuantitioe of wiry.

A case ai'depravcd quatite is rugwrtei 1n the fitment (14).
of a girl omrlnycd ea a cheap hurder. was QGVClflflcd an ab-
norfial craving for filnhy anu contndinatcd water.

Lichlcnetoin (15) in his article on rioaota paints out

that often Lanna reunitio ohiluren exhibit au abunrncl cuLGe

Schadle (16) Onlla attenyion to the ffiot that bu tun often
have an abnormal crav mg for amoeba and augnr. Cravinge for
tour or acid tautlng fonds, such as 1 Lone an; picnics, are
alrn wnito cannon.

n'flruvad njaozito in humnne iedost ca man in ocean or

10

hysteria. chlnroain anfi flaring pregnancy. accarfiing to Bar-
1684 (1}.

flora recen$ invGfltigetara havn observed aggravad upgatitea
1a rnnlnante sea an restricted raziaue. Devanport (17) found
the: calves fed on ratiaue devoid 01 coarse feed eVidanoed a
depraved agxatite and Vflulfl readily eat ahaviuge and chew
boards. rope. ecu. LLenevar obtainable. The animals on whole
milk and grain rutlana ounnamud large quantitioa of grain;
neverthelose. tfie out hulla in nucnhtlf Luuhol 9f vhale sate
a any. did uat EerVO ea eufiioient bulk in the rmtiva to satia-
fy thu mniaule’ craving far coarfia foafi.

fianborn {18) while attumyting to reign ruxiufinta an milk
and grain alone jaunt that 0&1Vee canaumed largo aunutitiea
of EhflVSfigfi. He atfitibated the floafih nf thu culvea to the
datrimunaal afiecta of thu shavinga. Lita older etmnra nna
ghee? on aimilnr ratioua. he difl ant mcazion any aggravcfl
appfittte as being ev1fient.

Joneo (19) reportea a i‘rm of dnpravcd appetite in young
raninnnta fed on whole milk diet up to otghtznuitwelvo waaaa
of age. fihoaa animals were uuufinod for tha mast part in a
ax? lot. fihero they wera unable to obtain engaging except the
whole milk a8 foofl. The usual Egg tame wera gaunt By ourance.
weak. 9398 atarlng. aniacl ounatantly grinaa its teeth. and
in unto or lung doltriaua;

McCundliah (20) working on the groblem of milk an a solo
diet for ruminante fauna tuna the calvoe on milk Glen alon.
at. 1:931? of ahu?1nca. gnawed fine Load 1n.the walla of the

pen and ate hair from afiah othr'a b06102. On poet marten

11

egaminuticn of thezo culvee coufiiserabla guantitiefi of hair
mixed High Gawain. or a Cheney like maturisl. wan fo¢na an
thu runes.

In later vara ficCundlifih (49) fauna that the lack of a
factor carried in well curea alfalfa hay prafiuaed a depraved
appetite in dviry culvae. In thin angerinont XuCrnaliuh used
twenty-Ivar calves. which were dividea lfito three groups at
eight each. Group one caIVua vote fed on whole milk diet alone.
Group two calvaé veto fed on whole m11£ diet auyyloneutcd with
a mixod grain.rctlnn. Group three onlvaa were fed on whole
milk diet supplementad with alfalfa hey. Yheee orlvve received
these reaiona ug to five months of age, at which time glfnlia
hug wee aaded tn the razlone of tho graap one cna tag animals.

Calvaa in groug one dovClopefi a ruvenaue depraved appetite,
and one calf iu prrticulnr started eating tie hm: from the
bacna of other culvve. At the 056 oikur mnutha this Oflf had
eaten near 3 all 9f tie Lair from the baca of a group number.
Qua degreved anpotfite grnfluully grew warsc and after a time
the animal wee nutioed to 116 down coneiéfirczle. she calf
boc¢3e week in the Kueea End dawn in the frcnt pfiabotna when
lad. Lfitar in the wtrind 12s gait became etiltvd and the 1953
ware 621$! at the knees mug Leena. 2km calf alto auvclapcd
irritability nad twitcnod coneifiorablc when touched. capeeislly
clang thn animal column. a: the and or the £173 manthe yeriod
alfalfa hay was addad to the Intlau Efld the cal! auswad
immedirte iQQQchent, all signs of aggravod apgatito difinggEEIQd
an& the cal! conziuuod an iwprova tartaghn4t the remainder of

aha oxporimunto

13

was calvaa in gragp tn: an3TGd the aumo goncral symptoma
as those in graup one. and all of tho GHlYCfi anv:10pod an
npgetlzo for shavings and chewud the boards a: tia pena. The
bulk canuaned 1n the mixed stain ration failed to carry the
neueueary factor needed in order to prevent the appearance of
the duprnvad angetite. At the en& of the five months period
the house of the front legs of one o: the calves in this group
were bawed into a rainbow shape. Lhen alfalfa hwy was intro.
duoed into the ration of thee“ calves all clans of depraved
apjotito diaapge&red and tha calves made a spoidy recovery.

Ike calves in eroap three chulnpcd narmally in every
reagent and did n3: chourel no of depraved appotlta.

Calves in grudge one and two ate plenty of shavings to
aupplg bulk. armvifiing bulk wan thn fhctot naudafl to flietend
the digestive tract. thus making groper Gigeetlon yoanibleo
But ehavinge failed :0 aerva this purpose. and depraved
unnotito deVulOpcd. 2313 work auggcete that there is n
benefiainl factor in alfalfa buy that prevents depraved
appetite: however. the nature of thifi factor hue not been
determ med.

H. J. haters (:1) found that animals placed on a mainficn-
finco ration davolnped n depraved appetite a short time after
being plucoé on tha ration. Che anlmnlfi rasorted to 883103
ooauifiorublo quantities of cwll.

Plan {40) is the numa 51Ven to a dieeeae common nmang
range uninule 1n fouth afrlco. T102 trcnslfltaa maple ficpraved
aypotite. The disturbance baa been a constant melanco to the

livcntack industry far gaura in South Africa. In fact

 

13

depravsd appetite 18 £0 common arzng cattle in eoma sections
that the csztlo breeders have comm to regard it :e a norral
feature in their rui1nle. in name sections the disease oc.uxe
in a very acute form. while in other sectisne it fifiyenrfl in a
more mild form. The t:;;:.1;1:o:$1:1 11:11.de rro those of a gum-ml
run é nu conditian, caauinziou. uua a leak 01 thrift. The
3033 anticoabla asswcrd u;uificctn.ion 0f the disease 16 the
nbnoranl c.*a% ing for Lonaa. rhou Manes Cannot be raunfl the

animxle will getter a: Jana mi h03vfi36fid an. c7-aume wnshiuée,

2:?

huge. c101hs. ruins, axing and 111 kinda of giecellnuenue
rubbish. anon the enimtle are driven away firoa the homestead
thug will yurfiifltfiatly return to the azuroe 9f the auaply of
these was :i 1618..

Some authorities on the subject rugurfi the disturbance as
due to a nervous £1=o1dor, since animals in the boat of can-
dizi on are uvurlly agff} .1oted n8 thay grauually loneo in alueh
theix ahnnrarlu mavinga ubuto. ”he Iepnrt (gut of grium Lure
of Mn an of Iauth “£1ica huVa avificnco that there 18 a relation-
vhip hntwoon the egpctranco of the diaceee and the {1ho:m 101318
0011311113 01” the :1. It Yen-.1111 8mm that 9.111: (11. 2112.1 11.111101: 12538
primar’ly dug to a deitciuzcy of ghozpnornue in tha 312$-re

.1.

uqon vhiuh zno animals graze.

1"” 1...;
g:
,3
3.
.3
’6.
f8

‘ 2
a
{a

 

LQigx 10
A Very closely related discaso to ?ice knarn ea 313310116.

has been a far ngLter obetaula confrauting the liVQBtouk

 

14

luduatry‘in.£outh Africa. Emmuiekto tranel&tad moan! "fallen
nicknoaa". The diaeaea noco.ding to VilJoan_(41) occurs under
certain 3311 and yaeturo conditions, 1nd is mare preValent
Waring oartain aeaconu 61 the year tnan othera. Eunay soil.
capacially WAG“ shallow or when mixed with stone. particularly
limestone. seems to ba thn moa‘ common formaainn upon whiuh

the diaoaa. ooaurs, and in all arena where anaickto is
prevalent fine sail in of a ennfly nature. Lemzleata in una
knnwn. or Very rare on farma whero the 9011 inrgntion is a £659
alluvial typo. Climstlo conditionfi at different aceeone of the
gun: plry an important part in the daValopncut of the dieesea,
and it may be euia that Lumllokto appearfi most commonly on

farms where the 8011 formation 13 finch that vezy little unintaro
is ratgincd. an that plant& grawing on muca £7518 Huicnly respond
to any change in rainfall. In regard to the nature of the
Vegetatian of the infected argue Viljocn atatcu that the

diewuee occure only on tha fitnflfi pasadre. and has HOVOI been
Bean an the Kerrao pasture. Que discrse in repartea not to
occur on 139 ganne fiafifiirfi wharo tun plant ”BrotgamL " will
grow. He concludes aunt it is probably not to much the

epooice at typo or Bagetezl)n that 18 involved in the wroduction
of the ciao-£2136. 88 111.0 uuiuvora‘nlo 015.211.11.10 rand 1:111 candiflone
to waiuh the planta are expotcd. Lauaiaktc hue alwnye been
recognized on a disease of drowtb mufi 15 Very 610E013 associated
with the annual preuithetlnn. The uieuntu eooaa mxro cannon
alrina can wanna: mouzhe. During thin Beacon of the year 1Lc1e
will bu an occaeiantl ahnwer oi rein. fallowod by a period of
drowth and 3 Ver; marked rise in tvuyerature. {n.0d1utely

following aha shower of rain the groan reegonfla with a young

15

eucculunt gr333h. 3H3 flaring the fallowing 33:133 of drowth

and £32 333.Lur. 3h uyoung pluntn b33033 111333 nd praoti Gilly
burn up. It is than that the 3133333 33r3 often 33333 its
ngjearnn co. 311113 the 033313 are grzzing on the burn. pEeture.
The 3133338 Lee be3n Ln3un to occur fiaring $33 winter 33 the,
but only under rara 3333131732.

'“M313:te 3t.ac3.e 1:11 bi)VunG8 . 1rr33.3331\a nf braed or
$32. How3ver. yo 33 3313313 333 cows in 031! or in milk 33.33r
to be mo 0 93:: 03311313. Farm3te r3 :3rt Tr.:32133t3 ensuring in
afihnr 3333133 3f 3313313 33 3333:, 3L333. 33133 an; Larsen, but
it 18 far 3323 33333313 3333.13 dazzle. 3333: engerim 3331 con-
3131333 3333 anve never been able 33 graduce the 3133323 in
33133 3? hereuu. n.13‘” braflfihfi from 3 333313333 free arts
to 33 13133133 3333 3 N33 33v:. 133 330 3;;33038 cf 133 a 33339
until uiaar 33VBr31 mnnshfi. 933 3133 roiairefl utumlly 331138
£333 four to ten m3u.h3. ”hifi 3133 18 3333t1333 rcforrefi to
33 the 1333333133 332103, 3333311113 wLen v13 33133 $33 ca 3.3 3!
the 3133333 £333 the 3323333Ln3 01 33 3333331331? 2 3:3.

233 genaraz 3y331333 a: 313 3133333 :5; no 31v‘1331 into

three 133;:3. us..-¢: 1. 23:33333. 3. Acute. 3. 133-33113.

9

In 333 03333 )1 tin 32rncato 1352, the unration 3f the Ciaaxea

.‘f

'\

18 very start. The 321331 21:83 333;"1: 33:33; 3133313
1333330: 3 and 133311133 t3 r186 213135 impeéir;‘oly fLor the
anuct 3f the diecnee. 33333 3333113 1 11318 within 312 h3ure
after tbs firsa 3;:33133 of thu disease are 33:93.

'Hith tha acute firm the 3333313: 33333333 33138 33 Juhh
more slowly. 33333333 ”“13311J drVLI313. being 33:3 nutiueabla
in the fore Quarters. Qua nninale 303033 33:3 3133 inn and the

3333313: 33333333 rloaly 130733303. the animal $133113 gate

down and is unable to r183 alone. and wkun eeaieted onto it's
1933 18 unable to maintain iteulf in 3 83333133 3113;3u. ;Len
the finiflnl is p0313331313 darn it first mniut3ine itself in 3
Eternal position, but £13113” 103333 311 central of it's body
and is farced to 113 atrntched nut full length on 38 3133.
Aating 33d ruminazion c3333, dam to partial 51:11:513 of the
throat and tongue. fihe temparatura of the 831311 remains nor :1
33 to 303:3. 3313313 afflicLBG 3133 the acute form are able to
withstand the attack of the 3133339 from twelve hnure to five

or 313 days, 3133 :3 avvrago of eucraximately 130 to three 61:3
in the 333: of the cases.

The subwacuto fora differs from the acute farm in $33:
the onaut 3f tho d 33333 13 not 33 sudden 9nd the course of the
disease is more pralonged. At first only slight Signs of stiff-
ueee Ere naziccd. 933 13333983 increafius Very slowly. There is
a 103v of 33131130 and a grnauul onset of 3 33313333 condition.
Animals 30 down and are unnble to rise on abaut the fourtenhth
333. Death than 1311033 in ab01t 33V3u 3133. nearly 111 of
the canes that finally go: doun.nnd are unable to r183 nlane
terminate fatally. fame animals never vet down.couplctclg, 13'
these caves frequently recover.

The post mortem flnflinga in the three aiffcrent farms 3f
the disease do not differ a grnat deal. 333 the lesions iound in
moat 03388 are 88 1311335:

Liver..............Fatty degeneration!
6211 Bladder......1318tenéod with L119
9 91933. 0 o o o t o o o o o o .Iiy‘perewla
Kidney..;..........fiyperemia

Abomaeum and LutCStinée...Fvncrwuia

1v

17

Ramon and Reticulu........30noe. nails, 030., Janna in the COHtQ41
Hoeenteric glanda.........flwollcn and oeau¢exoue
Genital orgrne............fiornnl

Hadinger (42) mafia a study of the disease from the etsuc~
point of vetholoay. and re orte on the charagterietic petgolvgical
findings in $331031 cases as fallowe:
Hyperemia of the whole organs, especially an; intestines
Hemorrhage of the epicnrdiua and engoccrfiium
Knee-enteritis in the anxll intee: nee
Fatty degeneration end brown pigmentation of he muscles
Sarcosnoridiu ieolnted in 911 cases.

During the progreee or the investigationnl work 3 this
disease many different theories have been edvancefl regarding

its probable Cause. Hutcheon (45) in 1835 wee the first man

to Work on this diecaee in an effart to ficbcrmine £38 cause.
He attributed zne cause to s Inca of 3hOzphor3u8 in the rcziags,
and reported favorable results from the fecéing of bone meal as
a means of combating the disease. BowLill (43) attributed the
cause of the disease to be garcly dietetic. 3L6 untreaterietic
symptoms being ascribed to mechanical interference with the
crntral nervous 238305 from preanuro age to a softening of the
bones from a deficiency of phosphSSCE in the retina.

Robertson (44) leolatofi an orguuiem (polymorphic bacillus)
88 the causal factor. he demonstrated the precance of this
orfianiam.iu muddy pools and standing water, Qua pronnaaced the
water eup>1y as being the source of the imiectinn.

Theiler (45) in 1912 advanced tha grafis toxin theory as

being the codes of the disease. fie yuapected the gresa of being

the cru611 factor bean1€e thn dieeaee occurred on certain $3118
of .paeturo, under 89005.11!) Eta-2:011:11 8:11.d;tioz1£. 1-10 7128 Int 15.1113
whether the taxin was contained in the plant itrelf, or uLet.cr
it was due to tha graduate of a taxic f.u3ae fiffifiiflfi on the
plants. 1Jtcx1ssit’e exyorizontul 11-33:}; curried 01112311106 1: at t.—.."

in order to determine the toxicity of éifiorout yluute ins
tanded to diagrave this tguury.

Hod 113159! (<21) $126 of 1:139 opinion taut serum; orig-is 1.2-6
con acted tith t11e etiolo m-g: 1f lunfiicgte. fiarovcr. Viljocn (t6)
upon inVuetiguting cnrcsn1ee in an effort to detoqune the roll
that was played by finrcoaparidiu Ln the deV¢;10 aunt of the
disease came to the conclusion that eercospzritia are Lernlcee
parasites in cattle. 116 advanced the idea than thse orgvu11-s
overrun the host 0121:; 1*"! on the and: 1.88 boa. 0:16 debilitr ted and

11201:; ted, due to some other 0111186. I11 017E198 of? 3211(3‘50 the
reeietance of the animal is lowered, and tae para: 121:5 are then
able to gain a font bold aim to mu1t1::113 r511d13. CLiu tcnfie
to account for the exceedingly large numbers of sarcocporisia
iealntcd 1n the unjarity 0f Cgfefi, but they are not. hotevcr,

a wrimnry cause of the dieonea.

”16110.? (4'27) was the first investigator to (ac-1111:1213
atablieh the true etiolayy of the disease Ltuzi1.uto in cat 16.
According to Thcilor Lz.;321cxtu in itstli may be lanuuly deteribca

£18 a 10rd of :1tmuz1ne pols-311111", c1311; ed ‘0: L10 1143 1-511 of
toxic carcass debris scat cred aboat the yastare. the eymptRms
of the 11183980 are simply thoee of a apeciiio poisoning. an;
.3113 cpgxmr 1113-1113: hoxzata 111 1111.10 00114111.}; 111, with in a few as:

after the ingestion of the 911205; or even within thirty-81:

houra 1f the emncuntrcted toxin be injected straight into tLe
blood atrern.

The poison or toxin is Qrwdaced by ”toxicagvnic
en9139J3tee‘. an ante Lic baa inn, rcnin nocut of, but not
identical with Bacillus Botulinua. fiot all cxrcnre debris is
paieaJnns, but Duly Etch Carrion as L38 been .3e iniected 1 ith
the z;,.~eci.fic organism. It is thug 918811.10 for 1‘rag‘:..z.'ut:' of
carrion. )utriiied flesh. or not: on bones to be poisonuxs in

one district and u)t in snotgcr; or poiswuoae rt OHL time or

 

place. an“ not at otLere, even on the cane farm. 3y rngoving
all carcvea debris Lauzicute is nutououically exclidod; and

I-

in practice it has been inund WOEtlble. by thor 3n h cleaning

 

0f 3 iaru. to rcfiuca the in;1dence of the ciao:se zlmoe t to
zero.

Qhe second paint of nutstnuding Signilicuhce 18 tLLt
parfectly n5;m£l cattle vill not touch pmui chow; CEIULES chrie.
no matter how numb ccnttcrcé shunt h pasture. but only tuoce
animals x 1110.; :51: on de. .rxvod a :u': uite run an; Enrique rlek of
ingretlug the toxic debris, and no wontrnctin; Linziehto. Tnie
degreved appetite is not in $6011 3 6128820 with a mortrli;:
incidence of its cum, but is merely tn incidental pracurror to

Q

dreaded L..z kto.
Dugruvcd apaetitee are connon over Vida arose in Youth
Aisles in which erziekta is uLLnoun. Lewraved ap.etit0 arises
whenever the Vegetion is {lcfiu 710m; in 3:330:33 )1;Jr0‘lu. and 18
apparently a manireeaaaion of yLoaaL01oue hum er. and can be
relieved by the feeding of prquiCfilly any digestible phoepLoroae

COQDaund. By feeding phosgLoroae campounue the depraved up ctite

 

21

is removed; the cattle leave the toxic carrion alone, and
Lanziekte is therefore excluded. Bone meal is the cheapest
and most palatable form of phosphorous on the market, and

is therefore always recommended. It may be necessary to feed
quite large quantities of bone meal. even three or more ounces
per head per day, where depraved sanctite is severe, the pre-
cise amount depending upon the district and the season of the
year.

The iirst method of control outlined takes the debris.
away, the second leaves the debris where it is, but stops the
cattle fromueating it. If proper applicati=n of both methods.
of control are as.lied, the disease can easily be checked and

obliterated.
Osteomelacia

Depraved appetite frequently precedes the condition Mn
which the bones of cattle become soft and brittle and fracture
easily, which is known as osteomalecia, according to Hurray (4).

Osteomalacia is a disease marked by increasing softness
of the bones, so that they become brittle and flexible, according
to Dorland (1). There is a marked loss of mineral matter trmn
the bones generally. according to Forbes and Keith (22), partic-
ularly calcium and a less marked loss or phosphorous. An in-
crease‘ in magnesium and sulphur is noted. _The salts of the
bones are absorbed and replaced by tissue not having the normal
content of bone salts. The method by which these changes take
place, as stated by Pommer.(22) in 1885, is through a continuous

building or new lime free bone tie no, a cessation of the

I} 4.,
Nu

deposition of Time and a loo 1 renaVL1 of lime frag 3L5 parts
containing it.
Porb a and Leith (33) and not rudden the False {43) while

‘ 1

EtaL13ina bone metabolism in osteeanlacia f and a arr so 138: of

v

inorg nic matter of tile dried bizzce. rho relative aueant of

inor3 nic matter lost see twenty-eight Dar cent eongureu niih

 

forty ~ei3ht and onc~n 1f ‘er cont 121 nor <1 bone. The Oilcinn fl
content was red uced near 3 one-half and the ghee herons content ‘
lowered about one third. She us n(:iim a sulphur content of
the bones was found to be inc;eotod nearly iour Lola. Tno ratio
of the :305 to C: :0 was foznd to be eat or t?.an Djiizle
uston and Ryan (35) and Ingh (3 ) found on the analysis

of bones of here a suffering roe ostc3311acie that thcrc*uss a
reducti); of ane, phflfijhlfic acid, soda, iota and nitrogen free
Granule matter.

As stated by Hansen and taller (3), shingle suffering
from this disease first show a pervert on of appetite and general
1088 of Vltfil :3; 813331 :Ihness apytrrs and the animals haVe a
tendency to remain l3in3 in the Stables. The weakness of the
animals gradually becomes more marked, spec ite has once more
irregular and Ira nose spacers due to arthritis oi the ox-
trerr “$129. chisel: in milk also suiicr a diminution in milk

flow. Ihe next 833 tons are c? tractozised by fire stares of the

‘H._g,. _ .,.

bones. Qhe slightest Lion, or even dufuulfif effort, may sense
a fracture in bones of th. leg or 3L0 ribs. The fractures are
seldom acconeenied rich enccscive bleeding and show little teuu
dency to repair. If the aninels do not receive treatment in

the early stages the bones iiually become elastic, soft and

depreeslble. Toe bonoe of the head are 11532113 the first to
suitor. becoming fires t13 ezzlcr ed. and the cocoons t ezue
610313 alcopficnro.

Dre legozing factors to the onset of tho diaerco.
accoroizMg ?uruer (36). floussu and $9119: (3), Eorhca and
K0 1th (33). are grovth, oropnauod, eta~ rvat ;lon enfi loctat‘on.
This mmlnd3 in due 3rinoipr113 to deficiency of the food in
bone for:ai lng constituents althoug h pfirhnpe duo in part to a
lack of the correct proporfilon botwcon the mineral elements.
hone forming or otherwise. contained in the food. It apocars
30:0 probable that it 13 flue to o lock of the correct prepor-
tion 0L mineral elements, rather thrn a deficianoy of :11 of

hen; because ‘onrrol (L7) has found ootoogalocia occuring
in res Luau: whore tLLere x39 plenty of 713: in the coil and
forage planto. as shown by chemical eanysis.

Kollncr (:6) re arts that in loo litiee {Lore the hay
end rwughoao are low in oxloium and pho~pLoroue. that farm
animals invariagly evidence the u9url eytitomo oi octeo 2&1rcie.
Bowite (39) attribut ed the outbreaa of oatcooslacio in 1994 to
a mineral deficiency of the food Etsza, par;icultrly a
deficienc3 oi phosaharwuo and oneoihly calcium. During the
year 1904 the; absorpLiou of 02.1.0 lam an; 3210 phone by the roots
of $123 plant a 388 hisdorod byo 8.7x3h.

Schewnort, Schattfio uno Lootach (70) fauna that n rozion
of hay and orts £0 to horeoo woo followed L3 ostoaoxlauia.
Unon analysis the hty'wee found so be doiicicnt in cal 113. but

no other doiiciencico turfl noted.

24

Since the disoavo 19 twat Canaan on vnrn nut a311, Ind
on 83111: leuLiLig 5.11 11m. ccuxrtL..L to Eismrfii {.71} Ind Linn-fail}:

(73). flha cr’Lxse of tLa ciseaeo must be 103Lci u;3n Le a

CT". 3 -.. .3‘ ~21, -. x -. 17 a. 1' 5' ;~ «H ,‘ --r «4333.. -.
C4lCLUHcy 0L M;A rhl coast, Luh,e Ln tLo LooL equ-ia, rné

n1

troafinent must caLxlet a! an; lying Ltu lacLiLz Qinerxle. TLe
add $13M of lina and 3L329Laraas to the ration :1 age form of
bane 3e51, bane ELL. or tri 0r ci-baslc c 1c;u; pLoLsL: to 18
r0333 ended 88 a treataaut b? Hutchison {I 7), Efigon (74). Forbes

8

and Keith (33) and flouseu nnfi fiollar (f).

‘
sea 9 Lenka 13
9-3 u‘au—Q.‘ “my... ~~

Another disease union is chrracter’ged b;' t depraved

~-

333301212“) 1:“: 05.6.3215 C"~x_:i.t(‘;}él£z. {.111

(33

nalignrnt Lone 6186258 of
he;p first made its a} Laranco in new Ecclsnfl in 133‘. field
and Lazar (35) abate that LL18 disease is identinl with
osteaunlscla, therefnre, iarthr ewmeifierazi3u of LL18 éTEnxau
Will Lat bu tugun a? La this murL. ":ty r033rt the dsu £1
8‘333315 CDHHQH :3 383$)3ulflcia and state tLat the factor
0211622313 rm: magi-3.319 for this fi‘:311.3:‘:;"1 mufzitim egg-erred to

ba an excess of org mic matter, and a deficiency 0: Lime txlts

1n the 3:118 ugan vaicn 3L3 aniurls w re ngturcd.

Bilf‘h 713313:

m-‘ Mm

Q

irst warning of rn uatbreag 0f Sash @1anyes ie

3%

223136
the deg nvod Lp.etite nwzlccd among 9313318 tLefi are naming
dove 3 xx th 2.3 at 83L 0f the aisturbaace. $his discere 18
part: culrrl; L0M'fin to certain parts of New Serlrnd. Louvrgiug

$0 3.81:0! (76] it ie not; 8 (1'. so: :30 in LLO trio 6:221:31".- j‘i' 3236: ten

in

but rather a yhyeialogicrl canditiwn rcvafiting from a
deficiency in the fowd 0: 10:9 e9£eut' 1 n1trl (-ut. “star
as.umefl that the def QL(:$ rusxltcd 01310: praczicxlly in
atarvmlon. or 111130 1,2; £031.; (1011311111011 {5:11.13 232-30 6011 . 011116,
or a normil canetlfiuent. present in abnormal QusutLtlcfi. rc-
Bulting 1n chznuic paiennid gnignls suffering from the
dieenee 1580 ix flu.t. gr? Hilly 13:;1u. bauage eaacirzod,
and iiurIF: :et donu.und Ere unable t3 rise.

Gilruth {27) has described hath sigxncgs cg pr;§rctvivc
uncnin. Unan thu run 3518 of the b10ޢ La found agate van a
diminution in two org n10 mnz.er content. Blond fran sick
said 18 cnnbninud on]; gun 111$ tLu “Jr 11 Fmounts of irnu

xide, and 9:00:13 dininiehjd um ants oi pho;phjraus and

patcsriun. the characteristic inor31uic can Mt10222 of the
LIOJd 001180. T3na.re alts of the anemic 1 nn113116 3h 8 point
dc cf-nttnl: twvrrd & decrease of the Llaté cells. 3103; no 01 a
made by Reid {?7) show conglzeivuly LLet ancwir is flfifffi
present in nnin le e'fiforing ram bush cicgnc a. fianinanta
Lre afiac ed 1:11“ the $130580 while nan-rigiucnte do not 8003
80800021019. Qatar (?6) sagfcctod Shit tie r Ezflu for t1 is
my be due to the (Ziffcrmum in title r12 ,txired far 3211: 111;; 12.1011
of Toads in runinumte uni non-rwx innutfi. The 615008c is nfit
canuunicable to he 51.33 cattle Ly d1 ecu coutaut. ragefiéion
of 111036. 02‘ 11;, direct 11100111231311. 2:219 tr"1.1ble is 01.115.111.311 to
certain areas, nutsido of which 3 daex nut sgrceu. Li5u11cd
animals frnm ru infected 3:00 are u 113 r"1vnr an n BJVGd to

a nfin-infoczed area. The vegetation in these iniocaed 1rume

consiate :1c1n1" of co as font 335 red nu. tnizw clovcrs. :zock

 

 

. ._, ...
_-= 3.4— .

96

may. however, n35preLtlg 33130: and die {ran the EiCunCEE
either in areas where there is moaning but red clover, or
where chrv is 113310 but c3uLs float.

flince all CDUd tiwne up :rcualy finiuted t3 8 d03161<303

the food C37 ml . particularly iron 3&3 yuoyenwraur; ex-

periments were 03nduczcd by flcnuea (37) in order to deter ine
the bencficinl ef:cct 01 any drescing the £311, is 3 acth sf
coutrallin: and graveutlng the a terse. gcterirle 3.06 :8 tap
drFEring for the 9311 are as 3011033:
1. Ejdratcd Iron oxiée
3. 31036. bane mud guano
3. 38856 slag; and s3pHr-pho: hrte
4. Fqur-pnOfiunate
5. Iron sulphzta an} super-phosphate
6. Iron cal hrte
The best 1083 in were obtained with both ewes Chi uniicre on
the 13nd drcaxed with 83per-pzaapucteo “nintle on the top
dressed pafidocus did mat develop the dicesee. and cwme 5:33
the lose in the full in prime condition Eflfi goad hcrlth. Cau-
trol snimnle on the untrxm ted paddo.:a8 derolo;:{:d thh {.iflhfié' es
in a for: ".1“"LC, slthn 11 they 11ml plvnty of focal, 0531'; tumor,
and access to emanailhg Lui-‘ho

:riala were also cond uc.ed rich the fa ding or agrap or

1‘

iron ytn.ph ta as a :3egic. no. 1:3

£1

:18 513%.;06. Li. (:3 v are able to
entirely cure two burn ELC3 rni3rle by feeding daily £11039 cos
of syrup 0: irau an:phrte over a period 3i rev :31 muhsne.
fieanee and ”atom caucluficd that the . dicin::1 trqrafimrxt w 1d

give beuuiicinl results in 011002133 a cure. but that the tap

dressing of the sail valid be a much more eu3uauic:1 3etzod

of affecting a control of the disease.

V ' : ' ' ..
fwucn , r treei;n~ .L";fiC?8
mw-~vlb "- ‘ __._—.fi ”w

 

One of the Iirat 83332033 n0ted.in out reeks of Ste may
or creeping sickness 18 the appearance of a depraved apqetite
in the aninxls. urecping sicznees is 3:9 n2.3c used LV 1r”3cn
to dealgnute a do: cieucy disease tuet 18 grcvalcnt in the
wine grass re gi)u of G)uthrn nacbz.ro

Carry (Ed) regatta aha: oatbrecke of the dice:ce are
more provelent during sensone of drawth, ct anich 2130 the
pcature$ become guite ahort. thus 11.:1t1ng 'hc feed eu‘nly.

At this t me the cattle been? a pour. c):ow ezzc31u21n. aes;nn 3133
with atrophy of the muscles and fat. The anin Is also retort

to the easing of 33n.e, Flags and even grasshoppers. In the
later Stanue 01 3h éLSCEEG the bones Deco 30 {:313. £3.231ble.

and (10331“ cd. Z‘eforznitltre in 2.2.3 B 111:]. 003.21 :11, ptrticxlziz‘ly

i nerves rhich

’.

in the regiou of the aclvis. wruduce pr sea; 6 o
ultimhtely result in the paralysis of Certain parts of the bnéy.
Carry Edggcate twat the dlecuec is Ufikfcd “3 u du.2i 01235; of
calcium and pha:phoroua in the ration and £32: coufynl measures

£h3;1d be Lntne direccian at a correction of tacee delicianci s.
Egfiton Feed 1051

Upon the cutout; of rninrle that have died 01 act on Ecczd
meal poisoning can (1211:2210 :;.11:.:zt2ti«i:e of 822m}. {Kin-"'81. earth,
6.0.. 816 a]: :5 17m: 2, 2.231111; $3.83 the 2.13118 1.: re .4142 a

daflrsved evictitc. This disease is the 335% 033303 in the

 

 

Fo't ern 8.3 es uLLre Gotten seed 3351 constitgtce 9 12350 ert
of the conuunzrtte retian. in an effort to determine the untdre
and symptoms of the .: sen e the finrth Caroline ;gricalturrl
$3,8‘1‘Pnt Lzation ( 9) condauzed eXQLrimcnte with cattle rnd
hogs on tin hcrvy feuding oi c:t:3n sued H«:l.

Calvce placed on this canr L czzt friled to gain after
being on the cotteneoeé mealrnzijn ier aLygt £*3r or :ch a his.
“cute 8333303: of thc QLECHEG Lorchr were nut conspicuous 33311
eh ut ten dzye bwfnr" the acath of tLe 3313218. the ani3ile
axedually lost thclrn ~ otite, became weci. d3nile tug CYiéawccd
a we y unthrifty :nd rzn down cvndini3n. Gritt ing of 3.; teeth,
labored and diffin ult brea “111Lg, and Suitcued feces vcrc s1:o
c 3333 e 33:03:. U33n the poet marten 03r3ineti3n of thcee
fifliJLIB 3L8 ucur;1 chrrac.erictic findings were tLe presence 3f
serous fluids in 3L0 thorfiLio Lhd abdominal cavities. and
general 13,3r1‘v $133 of :30 inneetinrl pracg. 3L0 liVer and
kidneys tinned :3 :2e congest m, rm". tin: Inge like: ice airmen

3-
J

“ ‘_: v 3 -'.z . \"‘9. .- I. ,r v‘l" "':-
'a ”L )‘1 " £l£\b Op $n-Ll 0‘ 25": -. J" : . -nie

r— v
['3

03:13:23: an £13113 with 1m)?"
eb03aenn of thuee c:lvce 0313 si.v;cd u)uaid€rflb18 E=nd £33 CrCVfll-

Ends on this case excrrimout ELJLGS about the Same gen-

eral *"3ptome tgnn wzre ‘viaepcefl in case of the C{1VL8. ?he
more 30330 a;mptwns of ‘he disease in tn: L051, havever. rcrc

£03: or five "T'm’t 8 b inre death.

yo...‘

in 57:31.10 Ct: 09. 1131: noted until

Cs; tug-t3 91 Be trr-Vitd Emma-T16

— um

02133.33 310... '“ic:1__t‘;‘3'7”

The cease of depraved 89333130 in ca:.,le has bmen

in the ratian by Rogers

Ittributed to & duflcivucy of cslcium

 

 

 

39

(5). Butler (6) and Carr: (38). Rage?8 pointe out that the

diaeaeo is must ejjnan 03.narn out 2112 t a: are depleted

e~
a! s3 .

Of their 11:30. 50335;}. )3: Hum. 5.241

A

~ _ . A. r ¢. , ,fi . fi. .. j ... ~ 3" .., . ‘A t q. .. -f . , H.‘ \-
LLI‘L‘IJ Gin-.uuf? 1a.!” u..0 Quartile»; 'LL».’_‘LU;.DG 131...“, .ctui (+7

Jr

a. . - --‘ I. . Q..- - J‘O’Q - " ,~ ~ ‘ x. s . ~ -. ' 'r , '- a. . ‘. ,‘3‘ . .'_ .- u ‘ I” d
a;li-J‘-12 14‘... Don'- «M‘;’ A; 0’) - («ECU 1-13j E“u.’-1'.uz.~ ‘CL “~10 b3 i -'U‘L 0.5
.1 . (a

1-3.. - -'.- t. --
22.64;..‘33 in ‘.:.~.: I=a¢4.);..

C;

‘3‘

3131!): has: abusrz'ud 21421“. 133.6,- ctuee £31.." £10;'i»i‘3.“ “vd x.;7_<,...wc
19 usuLlly a lacx sf minor 1 in the 130$. ZLe uniuals Lint
are zmt 1:11 .4..lirsrl "2,1,1; salt 1.11; 31:10 521'0 1.11158 the :"i:£‘:t to

baulwu ufdliuZGa.

N‘ 1 . ._ u'L n3 .. . -

9‘. ‘f\“\‘ ”a “2" '«'- = "'
...-. . 2.; 1:34.13 .?.. {LLLh-v
.«n-M. —-—.

 

L’hoaphorous daflciumy in both the son and the ration
has has poinsed at 36 a cause of depraved cpgetite by catty
(38), Green (50), Law (6) and Theilor (£1). Carry baa evifience
to 12110?! that in awe cit-:SGS the depraved ap;::etite prevaletnt in
commotion with creeping eicimcee is cmeed L; a 5.2110:.;>1mr3118

.‘£.-‘_'; ,0,
‘v“l‘ilv.{ .

def

fol.

Grean fwund that ec*to osteapha7ia {bone eating) is
due fio a phorphoroua deficiency'in the 8011 and Veyotuiinn.
Ho baa been able to bring about the condition experinanthlly by
feeding low phagphnroue rations. and was than able to relieve
the condiuian by feeding phosphorous compoun.e.

new suggests that a deficiency of phospho;ou8 in both

the so: and the ration is the 1:31:20 of depraved appetite 1n

Theiler has found that a phatphoroue flefiuicncy is the

cnuee or the depraved apgczito that occuglea each an important

_‘_- n _ ‘A I.‘ Q , . I--. -‘o.-‘c§ A: 1nmn‘nr§n

P10 1!"

finnrpharcue dquCLCncg has been the n to be a general
characteristic of .nuth gfric n £1116. the degree of dcf;cicncy
margins (3:12.16 what in the different, diz1..1~icte. in the phos-
phorous deficient Graze, dcp;sved noget t or oases-ungia
develop: in the rninzls prcturod on 1hin l:nfi. ”10 ccgrro or
for; of the depraved egpetlte, whether slight or LYXACQ. dryanua
to a 11:40 extent 412011 1:110 degree: 7-! 111-. infamy. in the :3 =11.

Lnnzicgto in caurcd indirectly by a deprrved rp‘otito
revult§.n3 flan a nro'nuwréue deafic;.nuy1u tuo 1-11, the direct
Cause being a ptouaine polaoning brought about 13 the infection
of the ca -rcas ebrie with a upecifiic toxoaouic aggro Lyto. It
is necessary for the ore Hui .*m to have a prwtein euketrcto before
it can prmiuce $110 toxin, 11121100 11" 1.11:: c," .1 r1 org-21111111 is raiser? -113,
or tiére 12 no decaying carcass, anzieztn cannot develo ,rogsré-
10?? of :30 H103r1eo of dearevcd 91'8.1-c in the Luiwdla. 0n the
otlmr 1121111, if 1:111: 21311 if? 11.): (1113101121111 in 311110 2111:1019. fifi")?£l’(:d
afuotite (11111-- = not. flawlop, 111:1; 31:0 i’tialf‘l:1fi move-1: 1351,25 the
31113-011 wreaths. regardltsm: 21:? 2114.0 (if!) .23 to *ri1ici‘1 thug; 11'; Lave
free ccccca.

[Smile]: 11.31 1112; 0:11;? 51111111 tut? 119.11: fixer]. feuding relieves
the deflrsved a1vc:ti.0, but Lo dctarnincd to 51mg extent the
animate of Lane xCfil necessary to iced aniaale in tLe difigzcnt
4 05}h030u5 deiio: 1:nt er: s in ordnr to :cvant the oeuurrence
of dupraVed ap~ctite. fine cm11gt of bode mfitl rui-ired to gro-
Vent depraved an 0:130 is dependent upan the degree of gLOB-

p Drona d.i.~ficiizzac;: in the soil. L110 86119 results 0‘11 be 011124.111ch
my the phoaghnto uauzrinw oi 3L0 1011. but this method 3f conzrnl

was not rocanmcHGCC b" "mailer bccnure it 18 prohiuitiru from an

econafiic 1 stangain
Thailar £133 igxné that Esau Ldul IOGHLHfl AMJLiwL (hi Very
favorable recalts 131n the granth 33L h filth of bgtL fiztflffl and

grawing fifli:1£l£. 32:3;0118r13 the 11:21:.

Irgg feflgiyncy

08130 mi deyeved 83:0 tita. oviJCLLcd b? ahecg “sifuria3 from
hush eiqguuec; Law to tLL Lac: that Luiaale paLBLrod an and

tag dre. ted Lita irozx €11 hLae edoleopo Horn; 13 Lu av cr3 respect.
Chock animals on adjaining plaza n3: zap arcseed vita iron Lul-

yLuto Lu.clo)ed b'ch ELLLuLea and auccuabed to the Lieuase.
_:£atcin Hef1c10n23_

303028 (5) has 213. ,,230L tLes in same cases a deficiency
of protein $63113 to be thL Cruse 0f ficfra'EL 89182136. Lynch (9)
stated that a daiiciany Of gratuin.iu 3L0 ration it niscu the
“it. It is reams-257311203 141:2: Luv-ye be
fed 3;)3013 €17 ICLCRt profiiuus to tine 3f far: wing in orLCr

>~ .. 5‘ _: be‘v... ‘l ¢.. ' .'.a
to Leap tuLn $.31 02.133 tuLLI -_1.

‘

Digfietiva LiSBLLLLLLCG and UGILLQQLLUtS LL30 Loan citcd
as a cease of dcp~avcdr apactito b3 unucun and Lollnr (3), no-
tosuh (7). 331Lh (9). Ezuuer znxd Ciodongr1tax3 {53) and Fox (11).
Houscu and lollar 23330 that in adult Lnidrls ficgraved up Ctite
often secure 2 a result of a well erLed d13.c-23119 Li tzrbLuce,

‘20 81133.01"; 312.12 shear" they paint 0:11. ;;.:~:‘;. 1011 l’l:;lz'ifii.tsd L111. «‘-

-_.

9

11) the bf‘n‘fit n‘F ("\"aitinfl fifal‘fl (‘50‘301’1'3 film ‘LY‘C‘VOA (21 n+590 1 run

 

9.)
I;

alimentary and digestive dietirbencee 000R!-

ficlnteeen asserts teat crib-bitere 14 Marcus is Ceufied
by e deranged condithn of the digestive system any a leek of
exercise.

Lynch :emnd tact with evine dep;aved ep-ezite is come-
timee seen as a symptom in gafitritie, chranic :uiigeztiaJ end
oven.1n cases cf hog cholera, particulrrly wi‘h the cnrnnic
’53 0'30 0

Heubner and icidongretchy attributefi dufrnved up etite
to nervous disorder. they state that permanent 9C8.liuf, con-
finement and absence of sunlight help to bring on an uttecu.

Fox likewiee suggests that coyroahepy (acting of dang)
in captive wild animals 18 due to a nervose disorder and
diecontentmcnt breught about by permanent coniiueeent.

It may be seen fren 9 review of thr literature tLat
different gatheritiee do n>t agree definitely ugen may one factor
as being the Cease of depraved appetite. It is grobably not ens
re alt of rug one definite factor, but 3 crn, Lne does 00 ur
under a variety oi’conditiane. In a number of essee it seems to
be the roe t of a dcfiviency in the 8311 of eitLer calcixn,
aheaghareua or iron. walla in other Ceres it 16 enured by

digestive disturbances and nerVexrneee.

‘T o t. ‘3 \ o ‘< s- 4. 7‘ n o - .
.IQVCuh-33 zed Line Aer “C933705 Avxctit-

--‘- we I." A---

 

 

a number of preventative and curative agents have been
Buggeetefl as a cure for fieprnved apgetite b; dif:erynt eutLoyitiac.

Eurray (4) recon ends the ranging of efifiroxim:tely fiVe g?hufi.

\4 -'~' 1 .f- “3.7-. . p .- ¢~.4-4 -‘ - 13].. I" .54.._. :.
tLree 42:423 C £15. a; the 42151.;L5 “422440 Le thlzle 2444ur4L3
.9...‘ a " 4 .... -.- . a ..

“kJ-i‘ QQFOIIJJV‘J‘I “o'2. ‘u 1.1.9“;

9"“) . -r‘ I. k? ‘~.v9‘q 4 .-1‘»-.
bufU’Iane 0.. .LLLIuoocoooooooooonococoa... )“MCLB
133110 4‘1.3~Lro..oooco...............o..o.o1 DJI‘d

"w .‘x .q’,' . -\I~-, - A , -,.l,..

\J‘HU'J‘UU h-’85"J-L5 llooocnooooconooonooo.ooo'zs Omuuus
‘. q“ t , c .. _‘-~ ‘
thLb (CO:3...OII} O’OOIOOO‘OOOICIOOCOOCIOIS 0.4;“..08
‘1 ,1 '\ . .
-O‘RQUIud £13.31. Lia.§2'0\41;......o... coo-ouoo-o‘; )¢:.u( (LB

:' \ ~ ‘. ‘ ‘ , _‘ {T " fl..v.. , ..‘ :- so..- 4" . ‘ ~ ~ In.‘ . . ,q ‘ n. ‘_-.
J uhul‘ Luau A3.t.n.0 (an) WU‘JL‘LL Lu.k:i:-..L{;‘..‘.a7.tc. 1L...“ :0 5:3 1d
'5'. r'~~-#Ik J‘s ~!v‘¥~1--‘--- -._.-~~ -. «'9--‘.vfl", }(' 4‘ ~ .-- ~\'~-’ '3 \ s
4.0.; teJ. be $3. )1 vllk. LaUQALMSIshJ-«g unavov a; )1“; 0.. ‘3 )J . 2+ ; a. -. (3 An

.2 4' I t *A - »\ .. - r ‘ 1‘ ‘ .f“ I . . '. "‘ 7 V‘ , ' r
LOGLB a- ode and amp-“:1! to 41ve grnlLs dz 5 ior 2 yL4LJd
of tLree :3 431$ a :8, e2 a curative agent.

”’2... .- ...g - r- g. .- ~ ... -- 9- . . ‘ . ‘ - ‘2. no- 0‘-
Luu teeutmeflt of flagrayed a .&.1ue id 859 9 b4 $L6

-«.'!- . -.- 4 2 I-- m‘ - -2, 4.... :_~ 3
{3‘1001‘683100113 LlLdtficuLfine 0f L13") 1x)li}.-...Lu6 4.1; {14L 3 ICUOLZ .(;;$'\Lt!d by
N, ,3 ('1 '31.

Vt. 1421' .L\ I.

'3'.'* ‘ ,"r 6‘ 'l' '- 1 ’- '. ‘ .V 1 . -"vvo'\ - ’.-. . u
JI‘ Lacs 1.1;“ "N$‘Jn (‘l7) (IO-“V151“o t“&$ {:" I ‘1) I), ..'\)t‘ :31-033-

‘1 ~‘Iv ' ‘ ‘.~ ‘ l . ~ 1 ‘I o- - "' - *Q~ 4 1 o 3".“- 4- U- -'

dance 4n 2142.29u Lb a leaL4le ca;e 4 : d3: 2* 1 e 04149 if

r" I .4,

{:L?( £1 “31332. a 811;» 41.0 4. J... 301.; 1 )ai‘. ("‘24: ;-)CL.
'1tl leflgz qf Levine a! Biteretar

”~- .— ”v. m “cl-cm nun-r -w-

.- ._, - 9 r ‘I o x . r. f' . ’ " . ‘A -. ‘ r z. ‘4 .. Q. :
U;,AU':'J(A O: 1 ‘¢'VDruUu (3","(4'1A2le 13 this) Ldit91'3'.1 0.2325418

Cf

- .1. . .‘qfi . .
'22:. 221?. IaguS, ezregs, art: lbs

for DDULS, 13)3, d1:
of cletLing. etc. It 12 2 wuan Jane with Le teras Pica,
osteaahxgia, golgghetia, pezhalogicnl glut: org‘ and cagrapLagg.
-108 (firvnsl zed ;QFLQ fieuraved a? ctlte) 18 the term given

to flevreved up 22:33 in Tenth “12102. 32te0sLe 5 ia (bjzxc 525135.
1: also 3 fare ef d£:“rn‘;cd 21.93130. Talgchgin an; patte-

logicxl 3113333; 8T3 turns 33 lied :3 0.L4V32944L.EL. or

craving for £11 .11.;22 of $0 :21 i.12~111:r‘11£;‘.‘3’.)71;21:‘3_1L.0_f3 Emma the

eating of flung. Lnr is a grrczice tLat is cumduu an 23 c pzive
wild animals.

fiature cattle and cslvcs, as well 22 other 0122222 0!
livLetock. such 22 Larvae. sheep, 80232, swine, nnL goultry
enfier frag attacge of écprtvcd apyetito.

Deprcved appetite is cirfactorized by a universal
oeuurrnncc. Chuiler re arts that an raved cw «Site L28 oni2ted
in Youth “friCG for Luch a long prriod of $139 that farmers
h5Vu cone to regard the canditian as nwrnrl in their 2313218.
Dcpraved epgotite hue been known in tPe “uiied btatea for at
12223 fifteen years. Tclch regatta cages of depraved
aspetita in Bantaua as far back as 1910. Humorous outbreane
h2ve 8120 been ruported from time to time in éiffnrout part8
of the cointry by various authorities. Degrevod tp;etite is
very Canaan in.“ichigan. nerticulcrly 1n the thumb region.

In this szcziou. during the Spring Qua £4348! mantis. it ie
not 2241n on for kn cuzire hard to became affll;*tod. in 2320
lazyeucc5, houcvur, only a few auiuala in the hard will Ccvfilap
the abnorurl Craving. 22¢ occurrence of the @122222 is

299; 22:13 mare .niVer22l in recunt years tneu it 222 been

in the 222%.

isLte, cotvvn seed meal pnieoniug, creeping eichhccc,

r .
cl 4:1

N

bush schuuuu an; Deacoinlncia are 211 21322 3 rnlutod CLtesrcs
to doprevefi sagezite. Duo of tLe 332$ chsrectarietic and
pronaunced 232 tons of 211 of tLaee 21222502 12 the abnornil
craving or depr2ved 23303132. 38131 ate. a direaae prevalgut
Luau; cattle in faith Africa, crn be cautrolled b; preventing

the depraved aggetito. A phosnharoua deficiency in the 2011

A

first ac:VCu as a QULME to aggravate an attack 01 acgrLer

.~-‘ .3 ’4. "1. i “f '. :1 4‘ 1 : 1’ M ~= ' v'" 1“.“ *"' . .4-' n

15-}.4kl UL "0. -‘-(4 1“. LLL’JG“ I-l“.fi-§‘A t, It.‘ I. rt: .J- U “J “5" ts; ”mu

0;. miss-met; arm; :35. debris, 1.-.-..gg; it; 32.4: CIILJ’CL caufto of the
d‘euuzc. 110333.: {Em-(i 2.102;}, poisoning, 1:8 rugsrfieé by this Iinfth

. .- . .1 . .z.. . '-.~-1' - ‘ ._-4 .:.,
C&*1%)1|.hu JBIIU$1LJIL1 ~A3£11~unt “uhul)u. uuu Clenglng thxauuz:,

mo; an in LLU tine g;uee ru_iun of nltbnua, use r£1u5 to Car
Ere both C ::uL:LS LLCZ are Charnczczizcu by u CtplhTGG LA c1128.
nuiULlE.LJL¢-CILNb ix 11133J1 fiLupanc in 19% “cslsnd. QULUIQILE
to .uhLUE and Auto“, le0 :uom prrxcrtuu.£§rczitc. USuUWL‘Ixu a
(aoftuuing of the bfiucg so “Zea Qua; became hritnlo aué ca.;1;
brakcn) is & diuouze the: is prcccucd by ataacLe of dv;::rvc:d

up asite.

22m cunt-or: 3;; (20523::on 53:93:39 Very according: to tho

o'mdigi mt: 1mm“? mad. 1; occurs. “1132.121308 uo 11:1; 1.311130
ugnn rn* one IECLUP L8 being the ULR£G oi GUJI£VUG L geuifio in
nlf Queue. In In i)ns mun?» tL‘Eu is r GtiiC;:n03 oi uizLur
Calaiam, 3h» ;Lqruus or iron in the ratilu. 12 has beau known
that thufiu dqucicgciua are 330 011:0 oi dogrcvcd z;_o$;to
accurging to 2L01111, Luahoe cné Acton. Ln: gogfrfi. an LLB
other LLhd theru are Cumcxouu natbzeugu r: ortcd, tLu camae

of LLich '!.n qnlj be attribuxad 33 digubtivo CurLLgC fats mud

" 7" WI 0 1 1,- I» ‘ ‘- Y'— 0‘ A DC I" . s D .,. " “- .1; ‘
I‘Ur I Odfihuflsz. LL )TJI «5-1) :40 A- 3‘A‘Lil I1 {5' .451 5; 111122.. ...,’:.\.lg. .)££-()r {Jyd

V I
n _ ‘y
’ )J‘.

:5!
z.

'1' ..-n‘.-- (A ‘ _-'- 7-. ~ 9'31: ‘1”... 7| I" ‘a. ’0 _ "‘.
$.16 ‘. )4- ‘b O.— 0-8{31J1L‘411u (:n\lgu ‘3 f U : “fig 3 (1"1’1 are“ t“? ‘al(: 114'. “L

2‘ .‘u" .0

troducud under 6399: nontxl canditiogs 1a 111~C8 an: be flue to

u lacks Oi a fretsr that LE cur1;od in w 11 cared zlleia Lty.

2kg Ciro for deJrade epgezite fingeudu cgt;rcly u;3n the

4 .\

t x '- . W.- .._ “.,,__ " -.... ,.~ . .. i 1 . f.. . 3“- ..‘s.. c .. ‘ .'. fl .-
\lllt.o-i “‘ illij‘ Chi-.‘t ‘3. ‘n flit: J.£1'. 0“ CC J-CA ~§:-‘, ' 33.1.3 ';’L&'~)l 3‘08. «)r '5‘ :‘n ‘

 

deficigncics, the cdfiit

""1 effect a cure. Eigwerm-

U \Jg.

dietlrhhHCiii’ or nervmmmas,

sought wt. and carrected. It is

.yrup of iron gh?‘ h?39o 893W‘r

a xtirce are of nzch Value for a

it 1?, tgnrefare. tin

make a etudy of dcnravvd nnnvtize. and deterwlna, if

0:342.)

. . a” o-‘:.
‘11 1a w.‘

~gine,

and also the taluo of difforcnt trevtieute

56

.e ‘ 4.3. 5.
Se m-norzlc to .;c In.1nn

u used b; difethVo

‘
v0
-) 3.6.1

at vertzue mineral
treat out of dggrtved
pnrdaso of this vwrk to

”aerible.

[”8 GATES

or wreVQntetivo agents for d prrred entetiz a.

'v‘“' I _ ‘P f ' -. ~i"
_‘th ‘ .~I. - 'A‘.: 1r] - ‘vakb

amaztmnf 3321021333

w.» ~v

Depra?ed apgetite, especirlly :mang dsiry fni£$18.
has become 30:0 preleeut in recent yeaxe. this is groauhlg
due to a depletion of sail fertility. especially in minersl
el 63101153.

Qhe general concensus of Opinion has bean that zLie
abnarn:lizy was due to a m natal deilcicnuy. Accoréing to
Theiler'cnd Green depraved up)etite 19 due to a uhoswharous
éeficiwncy, while gogere anfl Carry attribute it to a
deficiency of Calcium.

nork conducted by Reed nnfi fluffmmn {57), while
atuaying the effect of adding differemz mLAercle to a con-
cuntreze raaiun, has suggested the iéea that all 0:508 of
depraved apgotitc may not be due to a lack of mincrtle in

he ration. Calcium carbonate added to the ration of calves
C-1 and C-12 ffiilCd to give beneficial rezulzs. Lixc116e,
the feeding of raw rock phnrahnte to calf C-S. unfi codixn
Carbonrto to Cfilf C-G failed to relieve tfie depered up «Site.
The edaisiwn of arguerium ghoephste to thexntion of crlf c~8
and tri-cxlcium phflkfihfifie to the racism 0f C-Q fsiled to etap
an eggetite fnr hair and shavings. Ugon past martem oxaclna-
tinn twelve hair brlle were found in tLe lumen of crlf L-B,
and fifteen hair brlls in the runuu of calf C-Q.

rank (48) has concluded that depraved spgctite ury Lo
due to a lack of vitamince hat n13 in min r31 ratcuticn. yho

vitaminu tgeary is further Buzsnngzistcd by ficad and uni urn

[57) who found that a factor carried in cod liver ail rtliercd
tho depraved agpetite of calf C-lO ior a neriod of up toxi-
matcly five waeka.

:1 light of the present an 31:10:15.3 of the 8.1. sect it
enema feasible to assume that factorfi, other than minprLl .
deficiencice may be regarded as crates of dopravcd cg_cbltc.
It 18 the object of this ex-erincnt to continue the york nf
Reed and zuffwmn, making a thorough etady of depraved
appetite 1n an.cnfieavor to determine the yosiLion 1? mincrsls l
and mineral retention IaCfiors in he etiology of depraved
appetite. She r011 played by protuine, roughagee, concen-
trates and cathartice r111 also be deternlncfi by feeding
those as sapzlancnts to ratirne of 6313119 suffering fran
depraved 33993130.

A study rill 2150 be mada of’dcpravad appetite e9 it
oeuure under ordinary izrm coudi lone rucncver $30 03 orz:ni‘"
p caagte it elf. 7L18 work will be cnufiuuzud in order to
determine the rcleiwdrgip between dejrcvcd appetite tint
occurs in the field with that praducod under 8X§fifldrntf1

condl Ii mu.

0

£352 9; figporggrgg
1. It is pltnned to food restricted retinas to
culvee in order to derelop doprrved apgctize.
3. ”hen the depraved npyctite 18 OKLibitC€
effect 3f eupfilnmunting the restricted residue t'31:}: the

fallowing eubSEanceF will be arcertvined: (1) Calcium oar-

banato,.{3) calcium phorphato, (3) acid phvsthste, (4) grannd

limcetnne rock,.(5) raw rock ghnaghmte, {6) bane meal,
{7) bane flour, (8) sodium carbonrte, (9) QG‘NOEium phas-
jLnto. (13) wand 3.108. {11) tru“"‘e, (13) blood 35:1,
(13) w}.eat e3raw, {14) wLer3 bran, (15) elf lja meal, (10)
003 liver >11. {17) oxidized cod 1170: M1. (16) t3r~zp of
iron Lharpn'te. (19) elftlfa mineral mix, (30) mineral glue
cod 7170? 111. (31) flaiere M .. lylLur, {22) starch.

3. The follvwing feeds will be 306 as FifiglfljOHLS
.o a conomltrete r133 10:1 before the calves {Law 111qu of de-
praved appetite, in nu attenyt to prevent the devclo;3Lnt 3f

his disease: {1’ raw linreed 311. (2) paraffin oil. (f)
alffilfa 308. (4) calcium cerhonrte plus Lou liver £11.

3. m attempt will be :2: (39 3-0 vradzwo dngrmwd
npzetito in older CKIYOB by feuding concentrate ra313na in 3L8
formknf mixed grains. 2L9 cura3ive properties of’c minurrl
mixture cinilar to tLe minerrl pfi'uiuaolau 11H1 in £1Lflffi
L3: 311? 3hen be ctuaied. uthr calves rill be fed a con-
centrate raziwn any 1&30n3ed uith corn £33 0332 until depraved
epgetite 50?01Dpfig Regulte oh3fiincd by repiauiug 3L3 ;nrn
and cats with wheat bran, oats an; art hulls. e_aél v Lthe
of each, 3111 tLen be 01? —erved.

5. Blood counts are 30 be main from time no tin
in order to identify 3hc presence of any secontary 12$ nec313n,
or general systemic disturbance.

6. metabolism cageriacnte are 33 be c uflucted with
an1m1212 sufferin5 frorn deanved 59 :etite to ethLLune the

calcium, phorgharoua and nitragun balincee.

 

7. Obsor?ntiuns are to be made from time 30 3136
regarding the general ep¢enrance and canfiiti n of {nimhls
eufierhh13 with degravcd appetite.

8. Deterninatiéne will he made rack week an the
blond calcium, 5L5: 2.9w01 , chlariue. csri 9:1 dioxice. nou-
prntein nitrogen. protein nitrogen enfi hens loLin of
aninfile 'uffering from depraved appetine, in order tint the
b109a picture of cuiqus Buffering frag depraved 33,03130
as: be esldiad.

9. A Etudy is to be nsée'of depraved ggpctito undar
ordinary farm.condi 19ns, partic la: £339L319n being given
to the follayingz (1) animals affected. (3) £011 finrljsie,
(3) feed Enfi 3218. {4) curative and prQVentative agents

11.931011 '0‘; froce<3_':.1re
Choice of nimele

Grade fiolstein. Jersey 8116. 611012865! 0311'1’66 were

usefl in this expcr1:..cnt.
Choice of ?5938

The rutirne fed coneistod of the fallenin3 feca
83 uf's: (1) vh9le mi-L from Eloleteine hard, {3) skim milk
inan ml; ea d121r3 herd, (S) powdered cslclam carbonate, acid
Phaedhato, soaium orthonrte. calcium phosphate 01d magnesium
phosghnte. all cLLLiCLIIy pure. (4) finely 5r:und lim<e3ane
rock. raw rock ‘hnaerte. home 3931, 003131lrcid 1 {mr ' 0:,
‘5} preci_;:ta3ed bane anal. (6) syrup cf iron phasgLrte
U. 5. ?.. (7) alfrlia marl. final: gnsacrefi green tlfrlfa

laaves, (a) 02m Lzlle, gut or covCring 94 act grnin. (3)

when: e3raw, (13) \vLe::t bran. (11) fiarwe 1 n no; liVCI 111.

-_— _~pmr- . .

41

(13) oxid zed Harwegiun and ivor 311. (13 ) t9 nkzge, sixty
per cent pratcin, (14) blood meal. eighty per coat protein,
{15) pure florcre 9f eulphur, (16) pure corn ehnrch, (17)

alfu f3 tea, the wnzer extract of Slffilfi Lzy. (16} zlfilfa

miners 1 nIzture. c9199£ed of flrhi13.190"u€rcd. chxaic 113

pure mincrrle.
?regnrafiiwn 3f Feeds

The oxid 139 d cod 3.1ver 011 was grepcrefl b3 par3ing
air “:r911h cod liver nil Lentefi to a tenperature 91 one
hundred and forty degrees Centigrade for a turind 3f twclve
1113111" 8 c

The alfnlfc tea used was the water extrrct a: filitlia
hay procured by leachiu3 the dried green elfuliu k 3 with
13:9 warm water far tw;n%3-foLr h9are.
The ulfrlfa mineral mixture was pregerod by m Ling
the tubule-.od nm9unt e of ugly “OuElrbd m teri le:
1,305.0 grxne CFficin
56.0 " 3a
20.6 " EEC).
47.5 ' H5300;
162.0 ” KOFO
‘0
26.4 " K303
383.2 ” C833
143.0 " 2.32393
fihe eyrup bf iron phorphrte are “::ue b; CLCL91‘LHQ
Eight an. 81x tan.h3 grams of iron vire in sixty-LI: and

five tantha cubic ccnzfi. zai‘;tere of fihoLIL.r10 acia 3111? ed

4:3.

vith sixtyutto :13 five cubic continatcrs of distilled v~ter.
:30 resulting salutian wee then filtered lute seven hundred
cubic (11111111.. 313101-21 cf U. ii. ‘7. syrup, and: 111616 1.1:) 1'31 (1116

thUIIEEHd ClLic 01..-:cter~ h; ndfiinn aistilxmu uyter.

\ .

Cara;€hulter and Feeding retinas

 

The animals were cared for and handled by a can atone
feeder unficr the euperv111an of the nLn 1n chrrge nf the ex-
pcriwuut. They rare caps in 131-1111'1 921411., chcltcrcfl 1A
a enrll exuarinuntsl burn. 0nd were allonefi to oxarciso in a
lot which :sne area fram oi 1ble nut erirl. Fhavings vcro used
far bedding in r11 except a few 2908 Q5 nfizcfi in the e31m1.r-

1.m:ut51 act a. The enimnle had free access to vat:r Ln t 0

She animals were fed regxlrrly twice flnlly. E 1k 1
and cancentrcted were wcijhod on mare fieliceta Earlee s:usi-
tlva to a gram. fine cod liver 111. o iéized cad liver .11;
raw: 11115-111331 :11, mraffin 111 1.116. 2:111:11.) of iron 3111101 1117136 '
were mos: urea in a c; 11ndcr grnuurted :3 ch10 c ntimetcre.
All feeds used to eup-lenent the 1hale ailk dict vsrc stirred
into trim 1.11: 311:1 fed with it. {intern-18 11:-zed to 1112.1:2'10111;
a grilu ratizn re nixed mi 00313 into :10 griin mixture.
Daring thn mstebaliem p:r10d the feed and water 752 :11

wui he1d on grrm SC'ZIOS.

0011110111011 of ..x;1:?rir:1é'=rrlt111 1351‘;

—__._

.—

toir111 . Tue nn13113 v.-erc weighed a: tLo begin.1ng

1
_...- u

of the eagerifient and afterwards at intervals 01 ever; ten

days. 1t the and of'evury thirty day 3 riod tie nninzla
1:an weifhed three .1138 in 5110001571111. The awn-.339 of 1. .?e
weights being cagcidcrcd an the true EEight of the 111;:1.
The weights more 111 tsfinn early in $10 morn7u; be are
feed ing :r watering. ”urin3 the metabélism frriad Lite
unixnlu were weighed at the hcv-dnin., &1.d cu.“ succeeding
day tgeronfter daring the period.

Egganeiggfig. The folloving macs ur01 nte ? r0 fix an
the first of each n1nth. ngLeet point a: withcrfi, and
height at rump. 01:01010r0uoe of 0‘; eat just behind the

111': 113111-11. run the gr. most. 0101' 1:17.:rcuco of 11 Mel. .1190

the depth of chest, 10th of’che0t , and width at boats and

 

thurls. Thu length of ramp and length fran paint of Ehwulficr
to 11001: 310 int. 1

.ecwrfi of} sad. Qho feud cons*%ed was recorded each
any in a book groviflod for that urpwee.

Le? tn “be:rv:.1ous. All eynstoms of sickness 1nd

 

Q;

150089 “are recorded each day in a book uroviged for that
pill???) 83.
jflgqfigvg’gggnga 17111.0 1331:0313 of the 51.1.1218 mare 1:13.911

qr that

P?
0..-
V 3
)I
{QL

from time to time at a place enpccirlly 0111;

puryoae. The nnigrla more pitcud on a level :latiorm 1n

O“V

front of & Lrey hue? groaud ohet was marged 011 by black
lines into ten 0...;11‘512111001' 8311:1011.
Collecggjn 0143;03d E:W_1£E. 31000 exgplee were

colkécted regularly each week for chemical inslysis. Che

bload was dra n from the Jugalar vein, vinhout 15:: -1:, into

largo £1882 tubes, designed for that pur;7se. Procuutionrzy

sourea were taken to prevont the occurronco of any ch310L1
change, b; collection the sampleo unpor pore fin nil.
Lithium citrate was used as an anti-coagulant. 2:-e cm mica].
81213813 of he blood was determined by the ”X3Iriflfiut Ltatian
Chooietny Degartxout whosnro ourkiag in cooporet on with the
Dairy Department on this problem.

The 8233108 for blood caiuzo were also tonal imam the

jugular vein. 2‘16 blood me :‘110 wed to 110W freely into the
palm of the Land, which had provioacly boon'weehed in alcohol
to facilitate drying. From the hand the blood v99 drawn into
he Fponoer blood counting pigctte ( 1 to 103 ‘ilution).
Taiosono fluid. which stains the thine blood cornucclcs a
deep blue. leaving he roo blood corpuccloe unstainoi, WtB
used as a fiiloting agent. 2 18 prrmite the co mint: of both
the rod and xnite bland culls from the some sample. the
Sponour Zhoma-Jiese haomec gtonotor. o‘ich is r 1«d into 1 ur
hundred squares one-twentieth of a millimeter in length, woo
used Ln n king the culnts. fiho red blood cells in t:ont3-fiv
8.;uoroe in each of ion: COIJEIE were co nted, m:nivg & total
of one hlnuxed e zoros. this a:um.mul ti} lied by four thvlsand
gives the total n.1mbcr of red blood cells gser 031.10 millLao ts-r
of blood. She white blood cell count per cubic millim tor of
blood is cologlated b; unltiglying the total number of white
blood 03118 in the entire rulcd area by one thxuo:nd. Hano-
gloLin determinfitiono flare made on each sample of blood oxaun

'I

for blood 0011?,8 b" the coloronotrio nczioo.
I 1

_,_. .. . .‘_.

. 3-3: If _.._a.n —- _

-v-".‘-A_-'-" - r _* _

45

Egfifihjiigap Baring the not to slim 302105 the {$0 at
of feed 2222.1 motor woo swarms-.1: (lo: ornL-md on gram 122122221923.
The 13008 uni urine ware c3lkzcted in .uit mule cont 'nure by
competent ciao-2.1.3238 2212:) ro:'3::§-.-2o<1 on (0212;322:121; match the 22:22-
tire period. The c3llcc'-122:: woro we: Led oupsrately at the
63121 of mach ‘*.73222t"-21132r 12 ..2 “3cxiod 1.22.2 after 12123.20 '21:;
(-23.221213 :3 concrozivo 88.35.10 2.29.6 3222-2222 for ci2c..2.’.c:l 82221::3-18.
A conpocito 823219 of food and water “£8 01:0 zone“ at LCCh
time of 210.293.2254. 232223 Gui-23.2122 v 2236 22131 1.062 at the be 1122-11-3
of tho 2.3231222122118222 2criou. 822:} (213.222 C‘hlLZG 3-31.22 {332323-223 tilt-rc-
after. In orflcr that 220 ominole mith be 85y32cfl to the
ul ra vi 010% :3 of th. su-ohine Lhoy were GKCEClECd each
day in the cyan for o gerioa of t onty minutes. Che-chl
dotorminuti>uo for crlcium, horghoroms a-¢ nitrogen Lore

undo b: the - 2.:30ri:3 121: ~222t2m CLCLERi try "cont-22.113 on the

f‘

foods, water, urine an? 46038. From thoeo determinations the
average daily brlonocs of crlciau. phox.horou8 Lao nitrogen
on: o c 1C‘1rtod for each unifitlo

1331.11.ng of“ .3213'18. Tho P8 132010.13 domrtmunt of the
3117181222 of .otcrinr‘r Lieder? -220 pori 2:296. the ;.:283; norms:

61:23:33; 13:: inn on tho cachE.

Pl.

A .

 

1"gg_;ur§2fiti \22.3__o;2"__32‘~cprs=t'cd 22%. t3. :22'2-1223 in
00013232331322 211233. 111‘. J. 12'. 51:28. 0.3 32223 agent of Tao-231a
032mm, 32.9 2:22:12 .11 charge of the experiment conducted inroa-
ties-”10128 in re; rd to depraved 2299022136 in the 3222222212 regitm.

A utudy'uae mode of tho garm.conflit 208 whore doprovcd fig etlzc

occurs 222221 diffozo at 231112111 8112) 19m NW N 1'0 WWI-2'1 11““- d0

These eupglannuts were iod by the {233928, following the
éirecLi3ns gchn by the gem in charga of the ex exigent.
Samples of 330 £311 and feed were 8180 collected for
chemicnl QHLchia. one ontbrexk of degrarcd apictito on
a farm near tLe h0112339 was treated by incrunaiug the

mineral retention factor in the razi3n.

‘.‘. . ‘ g. ' “I." ¢.
..-'J.‘. '1-p. .2", . " 7I'M.
oJ—‘h ) I“: *2 {(F'L" J‘. J."-- J
fill-.44.“ M

“-“m-Iu—nnfi- m t»-

A descriptinn 05:11 calves used on 331. angerinent
23111 139 found 123 3321313 33313120: I of the 8:2- 2..-25213:. 532223128
showing the blood picvuroa of’crlvue Suffering frog Ce-
pruved ap2otite will also be 13133 on 92:08 (109 ) to
( 115) inglueive. 'ther gruyhe eh'w 33 the white .103fl
corpuacla and red blood count of the L193a of CLIVCS
anifering from depraved npqetite may be 5 and on pagca
(105 ) to (108 ) inglusivc in the 89.53-1x. Plates
52112:.)1-31123 the 1310131123023 of 11:-211' 132.118 (23116 cttzd from the

runan of caIVBe and lsuba ms; be found in the rp;onuix.

P9563 (114 ) to (116 ) inclucive.

g2}: 3-13

 

A grade Holstein bull calf born august 7, 1933 was
placed on aha GXgerinent at the age of Saran dogs. She
animal was continued on.thn exger mun: until his death
may 38. 1934. The rat12n consisted of vhilc milk eupgle-
munted with aheet straw. Lhavingfi W018 nacd for bed ing.

notoe nnfi observafiione. This sniual remained in

 

apparently'pood health cufi continued to mike good {nine

tn weivht up to Jtnzury :1, 19-4. 1bout.§ovenber 1, 19;3

"t:

the mlizat‘l develoyed a long; cos-t of 11:: 1:. Un Hover-Seer .36
he was muzzlee, but continued to reagin in good Egirita
until February 10. 10l4 when he ocvc13ped a staggering
gait and commenced chewing hie ton ue. U.3n the removal
of the n uzle the calf vould out chavinee raVenouLIy. On
February 33, 1934. the cal! had a convxlsion of aw.roxi-
artely five minutae duration.

February 37, 19d4. wheat agree wa° added to the
ration at the rate of one pound per erg. after the additiun ‘
of wheat Lirew all'evidenco of depraved epgetito flieap.orred
for the entire remainéer of the time the calf was on the 1
experieent.

the animal eaveloped a ae?ero once of secure chant the '
middle of aprilc Blood enunte eed hemoglobin dete'miNNtlone
made at this time pointed to the ;reeence of one 13. Tee
calf Eeoned to be growing weaker about fizy first. and “38 2

observed to lie flown at eVery opportunity while in his etall

or in the lot. fine weakened condition gradutlly grew more

breneuneed and on H13 19. 1934 the calf came cown and :ae un-
able t3 riee, apwareutly paralyzed in the rear loge. Blood ?
counts and heme lohin determinations made at this time ;

showed marted leueocytie infaltrazion of the bloee etream

' v4 -'---—o—r—-

along with a redaction 3: red blooe corguaeloe. In an e£;ort
to relieve the paralyzed conéitinn and get the aninrl onto
hie feet. c:1c1um.cerbonate and cod liver oil were given.
finpplementing the ration with green grass also f2 led to
relieve the paralysis. The animal became bloated one flied
Just before death

.'

1n the lete afternoon on £83 38. 1934.

. _ JI— __.__.‘——

GB

two cubic centimeters of iron citrate vac injected
intravenously into tLe jugalur reLH. ihle may hrvc been the
immegiete or ace of dcetL.

U“on poet mortcm cx:nluo.-oa extensive degenerative
cL‘n on were fo;nd in the Lioncgs,~iiv~r cu; Lctrt. “Ito
marked edema ef'the bricget and generalized anemia threagh-
out the entire body. the blood was Very pale in appearance
an; coxgtlstcd LIOIIJ.

The depraved eppet to produced by ioeoing tfiole milk
alone wee cured by a fee or car.“ ice in rfl ocat etr w. The
theat straw. however. did not prevent the development of
anemia end run dovu condition thick finally rezulted in
death. Zhe red elood coreuccle count wee decree ced more
then.one-hr f, while the white bleed corpzecle count wee

incrraecd eleVon times

Cal! 0-14

This gzaee Koletein bull 0:11 ere born ‘ epterber 6.
132., and plesedou the cnee.ixent tile iolloe‘l” fly. 2:
animal nae continued on the experiment until his death on
FeerE'y 27. 1934. The ration concieted of'uhole milk cud
cod liver ail. :havingc xzcre uzed for bede1n3.

Bot :8 ”23d obcegzggggggg Fifty cubic centimetere of
cod liver nil per deg vea eased to the ration on October
13, 1333, before signs of depraved appetite were ever man~
ifeeted. The apyetifle re aimed unreal but no evidence of
any 83 tonic éieturbence wee neticed until his {Lit bee me

Blow and clnggiah ehnut the letter pert of becenhcr. on

£9

Janneny first. 1934. feed was reigfifid for the first time.
The general unthrlfty condition gradually grew more morgue,
and the Joints Deanne Swollen end Very: tiff. Death £3110 ed
a very violent convulsion that occurrea on zebrunry :7. 19:4.
2oet mortem examination rOVrelee the pretence of
hyperouie of the hieueye, and multiple hemorrhage: 3n the heart
an& luxgo. Iortisne of the lunge were also in the 8 age of
congestion preceding pneumonia. {mull trees of necrozie were
found on thu liver end a Ewell ebeeeea on the ruuen. rho only
digeetive disturbance found was Ln tree of inflametion in th
smell inteetinve one a email quantity of Eheviugs lu.the r3 on
and the reticulum. She whole uutoyey Bezmed to yoint to the
presence of toxic substancee in the blood stream. which were

responsible for the ferneuieu of hemorrhages of eiiicrcut

org. {3313.
Outward signs of depraved aggetite were never gani-
fasted by this calf. nlthwugh he deVeloped Cyflyfioga of irrita-

bility. a factor cerrieé in one river all cpgrreutly prercutcd

the depraved epgetito. but did not rrlieve the convulsian.
Epl! 0-15

Calf 3-15 was a grade Holstein bull calf born Septemler

’I

7. 1935, and placed on tee exaerlment than one week of age. He

 

was continued on the experiment until éeeth, xerch 9. 19:4.
Ehe ration consisted of whole milk. cod liver oil, and a tri-
Ofilciwm phoaphete. Lhavinge were need for bedding.

gptee enfi ob8wrvetien8. fizniiestetlona of a fiepreved

ngetito along cite symptoms 01 irritability aeveloped ebnut

BO
tho:nidule of Jrnuary. the Calf had a canvulcian of about
one and, one-11:11? minute-s é.’.13"£; Sizm on Jinmry 31 £3.10 his

picture was Let a tstn. g second convulsion ocxurrca an

February'ao fifld a hird on ‘cbruw 7, r tar cod Liver nil
bud been afided to the raticn for six d ‘w ;s 31v ca‘ Liver

Oil alone frailcd to relieve tide fiegrzavcd sixctito, tri-calciwzz
9211):”)!th was g'i‘mn in a-.;'7.i:'i:3:1 in {an cffsrt ’30 roracaify the
caufiition. Qhe depraved apgotito continuoa to {raw .s;¢e
until the LniuLl died in a convugaian on Karen 9, 1934.

Ups? {amt martenexzszixlntimz edema 01 in ;;ia;1-.c-;.'z2,
and .‘1111‘51'3‘10 ho: lorchft of the h:;nrt 51161 lungs were LLJN.
The li?er also sLo'od exzezlsive ta :3 cogenoretinJ, Llong :ith
C no c3ngcstion. The rurtnl cantained £170 hair bells. and
both the rlmcn and the reticuluu cant: ued a 31111 gufintitg
of shavings. Chore wcsro tw on: of gastritis in the absurvam
an extensiva arena of enteritia iu.tho Enrll inteazine. In all
prabability the areas of CLtorisie more the lancaiate Cruse sf
énfiflh.~

It will he noted that and Liver oil and tri-crluium
who 3hrte did not cure tl;e deprrvod up ctito, :nfi ap.crcntly

baa no office on the prevention of irritability.

f1"

£511 043

This grufio Holstein heifer 0111 was barn Octobar 13,
1933, and wa. plccod on tho exporinnnt the follouing dry; :Le
hea'been.con31nued on :aie ex>elinarnt up to t}e ting sf writ 123
this tLeci". TLo :3 ion an ' varied from time to 21:36 accuraing

to the Loanior of tLe calf. 9:13 nili. cod Elver 711,x11a112

51

111110111 .1121. Llood r1911. cyr: 19 of iron ho mt. 111.6. sodium
chlorifle were fed d'u ing the cxpcri1cnt. fhnvinga 1:10 used
for heading.

L .,_cs _:'-_11-:’. ojmjrrmz'iduféa. The first; indie-$111111 of a

It“!

 

depraved a .- of; to tree observed (113.1111; tie first: of January,
19:14.1.0112321ecnr1 01101311631115.1115: her 0111 v.11. 55.11061135531151-
lish fo1nd that slfalfn hay prevented deyrnved appetite it
was thmgjht advisable to add an 2113110 mineral mixture to
the realm: in "1.?de to determine if the: 11.210111 cor 31.231311
found in :. Fifi-1:31; 11:33 $1.28 the hencfici-‘l £50011". 1101152111. the
011’. .1f.~:. 1121:1111 ( one 1211111106.! 9 27:31:.81111113 ) 11:-z: fed for a
period 01’ 1:11:31 m1:1‘-_.hs 1112113111; results. 2110 3:11:11]. 6:115:91'051 a
severe loss of 1.1013111: 0.131113131111113 :firiof. 911d deviaped a
canvas-*0 09:1,: 0:1" 2.3.1:. Since t:.(: 0113:1111 11.3.1 1:1'11 .11:-2:11.11 (lid
11'): relic-1'0 the acgtrevcd (21310951136, cod liver 0'1 012:: s:'.€-.0d to
the ration on tiara}: 1. 13.;4. The cam: ition of the wit
1:119:11 1:013 1.1;11'0md, the com: 'bec::::'.e FliCk and gratin we
resumed. the 5111:: 1. 1:2)". sever. 11:1 113:. entirely recover from
the pres 1:109 of e:1.,};ing 1::r tail. and: at times, 1.1::rticularly
after fes'éing, 110.1111 rev. rt to this: practice which my have
been due t4) habit m 33.0: t..:n a empreved up :ctite.

The latter part of 11:11 the 11111191 started eating
commem‘ulo :.;u::1..‘s; itiee of urnuro '11119 in the «axcrciee lot.-
At this 21:10 1:: 21101111110 of cad liver 311 1:18 incremed to
fifty cubic centimeters per 6.1.3:, 12111011 was ignored by a gain
of t'c:0. Var-five palm-£8 in 11.95.: :11 t in tan d:":-:. 2110 craving
for rmmmo 51:20 abated to 0 21:21:06. degree for a tin-:1, but on

June 11.12113 1:111:11]. (1.3. ..... cod an {.3 :ctito far sh::vin;e. md

by the latter part of 312.110 11 :11 rem-rind t0 £291.13; '11 1mm 1:11.11
renmma vigor. 011 31113 11".. 10.14, 0111'. 1211111134 5:12:19 01’ 1.111111
meal 31'1" (“193 were {1111081 to t:*1 10 r1131 11. but t2“. 2:15:11“. bur-l 3:11-0-
tein 81111-3.a"::'"1031t (17.11 21%; i“. Int'o €137.11 «15:1;‘91'51'1111 s' 1’3j5('2ti.€.(~:. $12109
oml. 111111.11 area (1 of; lfr'lfe mineral 6.1::in failed to relieve
the abnormal craving, the 1.1.1.7127: mineral 131:8 incrcz." ed to one
hundred. and fif t5? firm: c912: dry 1.210 fire. 9:; 0.1 Lugufit. It
18 of {2:10.012}. interest to nuts hat 531101'1'1111' 1.11111 amuse the
{3117.3 '1 09:11:11,11'311 :3 gr: in £201: $2141 0 1:21.219: strap that fund run
51101111111313' fibrmn into the examine lot. In 0:110: to fitCVCIMZ
her acting foreign r'zctcrirzl the (2911’ was 1211211196., Int m: 1': 1.3.6:-
1086. she vauld vark manure tgraugh LLe maeLca 0f thczuzzle,
and 0011:1310 lrrga {plantiltios 11‘; n time. The Comm]. (1011111111311
and thrift of the 01-11", 110"e‘:'s_:r, E‘uffcrcc} :2 Cove-re 1129;131‘022, 1.110
in all probability .0 :1 1:01: of wet er in the ration. bQCfELZETC the
131113111 waxld not drink thrmigj'h the muzzle. 1’11 ”tor the .11'13116
was. rntzovefi 1111' 901111121311 myroved although the appetite for
manure was 8.111 "ire-sent.

.113?th the blond nos-1 c.1111 Elit-li’a mineral had been firm;
a fair trial #1 1.113111: reunite. five 01111-10 cneti {wters of (7:2'1133
of iron :‘311’3813‘c: to ”11.13 2:13.011 to the rntian on 1111:1183 1, 10;.4.
The syrup of 1:911 :11m:;111r1te 1.112'11"ir:e f1: 1.1.ch .o relieve the
abnormsl crlgavii for m:.1“1ur0. 0n 00 Sober 8.10.4. the alfalfa
mineral 2111.: inc rented to two hundred and. sixteen £1‘E1.“1{i!'.6£2§,
or the fine-1111’s of minor]. 43- :zivnlcnt to the 1111;101'12'1 emu1 3.; ed
in seven 3311111553 of 21:391.:311 111'}; in :1 further ath-zmgt to cure
this dojru'avit'y. though the incrcsee in alfalfa :93 131-51

more than 11113310 to :Js'ct the re .nir<zt1:;.'n?. for mizmrrle the de-

-l

preved appetite still 111.- eiesed. 5.1111110 the 1111:7111 11.1.1.1
dew-1101100. en 0 1: (.11::- tcd 1211‘. run (1011.111 1:011:2131911 it became
necessary to 1.12113 .1 11031111111 2111 1119 in 11.1: 11111112111. 9n Janus 11;:1
5, 19135. 5110 F328 given (111121 parts of 2.111.016 2.1111: 2111 131.131
121111;. 1111;_1f11;:;0..$ed 1.11:1 1:112: 11114! c 1111:: 06.1.13030 11 01" 113111113)

01 111011 (111029211110. 211111 11011111111011 hoaever. was not 111.11:in
iaf'1r0ve1'1 1.111". additional 6110!?“ 111118 61131121106 11;? foefiiz‘ag 1:11.010
1:13.11: 11101111 21.1311112211211ted with the 1:111:10 11.1.; 1.1.1111: 01“ 113111111.) of 1.11011
11.111311511111313. 2.1-0 deg1re'1-‘edt1 m1__:c1 $11.6 111.111 11.: 111151.011 end 011 1.1.6
1111112113111, of .‘;:‘.1;'.- 1.331, 19115, 8. 111110 .1110 wee $1: 1511 chm-.1113 heir
eating 11.. 111111110. This picture 11.111 are in the 8-1 61.11.11: on page
I 117)-

310311 00111138 taken 111011 the to time 1111.11.11 to (118-:
Close 1.111;; 10183171181111) between the de: Jrevcd £111cu1te and the
blood cell 0111.111“).

2311112 1111111111 11131.1 had one of 111.11 2.111191“. ';11rci.stez.t (le-
praved 111110.1411. of 11.113 of the calves on 11:21:: e:~::>cri:.1cnt, and
18 the 0111;; one the: L118 caucn 11911111'0 in nu: 1.11111 .3. "11116
manure eaten, as well as 111 eubfitaucee fed, 118k the 308:1L10
9.101117. 011 of 1011 13.1.10:- oil (‘1’. a 11:11: innrovo the depraved 21.11-16-
tite. During; the winter 111111121111 1.121110 111.111 11111111.]. 1.1111 3111:1111 in
the burn a causidereblo 111:. of the 1.3.1116. an 2111211859 of (1113111;
four 1101111118 111‘: chm-111513 were eaten par (:15. If. is 0111.11.31.11:
that the depraved appetite in this 011110 1.1.1113 ch10 neither to
absence of 11:11.1;321539, ner to a lack of 11111111111118 01111113111051. in

alfalfa hey.

Calf C-l? was a arcée Ga runny heifer calf. born

July 25. 19.13. and gleam on '11:: 92 133013.: 1.1112: run tire) Linn-Ind
days nfr 55c. T49 ration up to six m3L‘LL of ago 0 nzistcd
01 Silk. gr: n and :1fclfa Lry. Let cagrr113 m1 ration con-
Eifited of grain ELK? 11-13, :11f:;1f!2 2051 am mun: Etrrw. {I};
canpoeitlou of the grain mlxture 15 LL follors:

230 pounds grounfl earn

50 " wheat hr? :1

35 ” linseed oil meal

25 " 0013203150861 2728151

7 per cent alfalfa minergl mix

Shaving? were uLca fbr bedding.

1391033 __P'_i'-1'11 obs-131'? 3:13. 732:9 (1:211:31! 1 made 110 33(3312113131.

 

 

gaine in weight after being placed an the grain ration aionc.
The fires evidence 2f dc;3r Va 3;) 031 we was rocoréod on IWrch
3. 19 .24. 12; m 6316 was (33.1311 11 2:13;; 233.6 LuilCingg and eating, flirt.
rLo depraved cp;etita grcaurlly baccme gore echro. tag on
flpril 5. 1944 she Lee Bean.catlng hair from Inoflh r 3311 1's
beck. Her nornnl up 051te fz3r 100d i1nr1.y ‘ ilcfi. 411L118
tea was then efidod to the rutian at the rate of £332 pounfis
96: d2: an 1pril :3 in an effort to 2-3 up the r; eaite. Low-
evor, the algulfa Lee was refused after 0 “Lt C ,8, uni the
depraved apgefiita 62111 p rzieted. 1Lea1 e .TQW'VES ndied to
the ration bagizLui n3 fpril :9 by r1 3 Ling the Lhavinga used
for bedding with wheat 8 ram. ELL éeprevofi ryzofiite cutirc1

diEEfiyeurcd mi hin.thrue weeks time after tLo cn1:1¢1 Etaz ted

(7‘.
U:

eating straw. J tougorary impronm;nt in canaisi3n use
also noted. no OV‘I. this Vi 851110 ed as 5r tuiu5 31 the
$681311 and frl)3;.131§ 1-3 the 1.101135. 1111;210:511 2.211. (18;.112‘2T0d
nppoti 09 was nut UCNifCEifido the gradually grew reagar.
and wee observed to 113 J3mu.m183 of tLe tine vhilu in her
stall. 3n Juno 7. 1944. cod iiVer oil ves.givun as u
nuJ cine, but the eniu 1 J fled the follo.ia5 flzy.

Upan roet marten examination a ficnertliucd 1 $0110
and eJuaic caudition tau ianJ. There more near ) 10 and
605::nc1a;ivo c} an an of the h.art, liter and Liana; , 1nd

wr.‘

extensive necrotic pncunnnic. 5n 95.1n‘ive area of c tar;w2

dquunitla mac the 0111; di5 :c ive dietu1br1xce arid mt.

33101111 co mist) 1112111111 on this 1111121131 failed 1....) 11.011 any

relatijn Lip between the nuaber Di white and red blond calls

an the de'51r vca appetite.

:hceo rrru138 indicr.:o that Jerk raved apaotite ury be

prnducea us ruugily b; fencing a grain mixture alone as on

a whole milk diet. 2ho same mluurrl Qixture as fauna in
811: lie 11‘” 851111fuiled to r:--iava the depraVQd 2pgutlto,
indicatin5 further that minarule are not always a cure for

flepraved appetite.

Straw cared the aunor.:11 era: in5 f): tziu‘ nut c1r1eed an

food. althou5h is fsiled to ameliorate tne onscznuud con-

(31:31.)!1.

_§§1v53 5-15, 5-19. 5-30 1nd C-i

Theee grade Holstein heifers were raised under

" 4» ' . " .‘r L" [13.6
approximntely the same conuiuions unuil £91: mon.n§ of 5

 

:1

It is interesting to nose tht the wheat

 

(-1
cu

The ration of these 3111:2318 du; 1:131. '1218 §_i*:'.‘1‘10d camiu‘soé of
whole nil£.eaim m ”1;, corn. 05-3 aLd timotky'hry (ca lib tum}.
At the can of zaar m :.hs ti'2cy were 3‘.lnccd on a ration of
15121035 11:5Y (one ‘H.:.:‘;d pat dry), potatoes and a grab; mixture
of the falls-“LL; camoexiou:

130.0 302* :38 hogan?

130.5) " diefiil’iers grin

53.3 " wheat ‘ran

5.0 " cotton cod not).
2.5.0 " sodium chloride
1.0 " e 35.3. L11 31-10:? Quito
1.0 " d-cofiiua yhflspt: to
0.5 " 1323;10:3qu cszrbomrte
0.5 " 2112311081117: 3131): pint-to
0.35 " pats Siam CLloriflo
0.35 " potaccizz carbonate

{10.0 art-.218 iron 15—th‘50

Heifers 0-18 and C~.:O received eight. pounds of the
above 5min mixture in och. tion to five 31:21:18 of 30383908,
and one pound of tincthv hay par dry. C-19 cm} C-ql re-
ceived 31.0 en: 10 mi tn mtg the exception that three per
cent 01’ the grain runirm emaciated 31 crlcium carbonrte.

After the animals were metric-zed to 16-29. 15.;zit(:d
ems-mm 031' ro ‘gfid‘szfl they 2511 demzlagmd a 0112?:ng for Load,
Ehavhlgje, dirt, etc. (3:211 tic-:31 (cvelaped c Vary mz.r};cd
appetite for hair. and etc coneideyflblo quantities from
the bad-:8 of other 5111?. :19. Cal! 0-16 1.11210 cholomz-d en
appetite for mod unashavinge. along; with. 12.1211 221'. clear ec- of

Irritahility evidenced 01' 1011111? 1:}: a: 2.23110. 3ch int-1101's

were placed on.th 3ctubolisn oxgzrinant 13 0 jar t3

La
La!
HI
L4
H
\r

Met;

'5

tbs 2310131, pho 3333339 an; nitr:);on Llencoe
of nuiuuls 83;,ugiJJ iron depraved spgetite.

It is of 9303141 13333;:2Ls $3 ”333 the: tcho 3312:18
did nut 13?(:lop dcp‘avod 53383130 33:13 thy: wcrc receiving

in .. . 3 \ - .WCQ \ ‘ ‘- " ,‘ . , Q- ,.; —\ ‘ o 3. . gr - . If"
all 0$ 13.18 ti...‘) 4.." 2: y t..-.'._T'7 \ 333.1.“ (.113. L‘n‘lu L3 2).)“ {12 tl.e

allownnce of hr: v92 1;:3i‘cfi the a prz"ed 23 03136 became

a

" - ‘ H‘. ‘ -. ' x~ . U- r. -' .9 ‘- \‘ -\-v\ C 4‘- ‘. '2 A 0'
eviuuuu. LL38 13d1333LS L'Ll-tucr Edna LJISKC» ED C~4t° dfia

9-11

'4
C“.

be due to the cL' cucc of a fine so: car'it2d , LL:. aiuco the

retisn was age us to in a a2; oshur r.Epcct.

Cal! C-B”

‘ O
III-Onw- u...-

 

3
/
A grr‘e hole t.in 0:11 329 born &cccmber 18, IDLE and

was 3leccd on the er303130nt the iollowL u; dry. She has been
03 3ntix laud on this experiment up 20 3h; prssont Limo. 2L0
ration was varica freq time to time according to the Lehnvior
of the c="1:f :23: 372.311; 2:11., {3:13 3311‘s., 3133 1:2 1." :':., (:06; liver
.11. wo:d cchc s. t autn o. syrup 0; iron stosphcto and whact
brnn. :huvinge are being ‘966 for Lodiing o

flqifg_fnfi wav:vfif ”1V183 than first 313006 on the ex-
p rimnnt this hcifcr Buffered from a ecvcre attack sf scours
fiiat was caused h; digestive fiiuturbanccs. Chis Louziti3n
wee tea LL11: izp‘ozed , ho chr. by i=3 Eng cod liver 051 :or
a periofi of t303ecue.

BefDTO any EILHG of fiepravcd cpgctite {are observed.
the» ration was sup 1a.. “ PM: (1 with two 333-11er 8 Iilf:.li‘tz ta per
day. beginning Hrrch 3. 1944. The alfalfa tea was incrcaeed
from ti: :0 to time in (an effort to msintfin her normal appo-

tite. A unxinuq amount of six pounfia per dPE'TfiB fLuLlly

reached, {2.22:}. 6122-30 1221 Lizzie-2:31”. t2) feed .2323 2:22:22 this 6233:2111“.

AI

toxulted in 8633:2352. it 2226 (1.80031: 3.1661. L'hc cliclf-“r ten

“6268 observed to yrclong 2:226 1:233:11; 32222:.‘iod before {in (lo-
primed appetite 1-::::2t“.'22;d13 r1'“1...: 630d, hat on June 6. 1944-72,
the 02:11 was seen outing hair from the bag}: of one of .2:
other 2222132116. Since the dupraved appetitfi for 32:31:“ cantimlcd
to grow 213m acute-2 11: bocz‘me 422:.11’222321‘. that the t.1£:t1i'n 1:03 2:126
not a prurntntiva ageinet deprm'ea apatite. Conscfiently
“.120 elfrli’a tea was (liecozmimmd .222... the 2.231016 milk TIRE
6:;u3;.1:162<2ntod 22121:“; 0:26 hundred arms cf 22:19:35, ashes (12.23.13. The
minerals in the 3. cod 5:2.08. hTJ‘JC’Ct. 2“. filled to brim; 221323121:
2:11;; is 32:01:63 1.12“. t in the 1123;):- raved appetite. In £2.20: 131218
appetite for 12211“ 2315;062:021 that do;2rm“‘~3ci uremic 31121: be
due to a fieficiuncy of the 22:23:53 2205. 6. “32:133.“.‘23. 52'22'280 "211322213
tanks“ {3.0 M26 8.3.021 to flu.) retina at the rate of one puma pct

4V

. 9 #7.?
1012 l 2;-ect

(132:7 an 32122:: 15, 13.35;. {3210 twimgo 1121.3. 2.0 bone:

c.

on th e (103.. “um 2:31 2.3 3‘2.
ration. an £31315. 1334.

C

no “Eartha cl; 21:03 were 2.22620 5.21 the nth: 22.232331
.7.‘2;'~I.€:t $2.2, 13;! , 1.21212 it bet: 6:22.20 m*;:..c:2“ that the £22 ,lcnc-nte
111 2.123 rasitm vcm not ameliorating the dew: 1'06. 23““. ctito
“”1311: of iron "212:2: h-"m 22m: 1.2.2.211 added to 2.136 I‘thiOXl in an
attesxzst to r011 on; 2:220 cox-221331.212. Shortly after 1.1.36 Grunge
the upmtita for 122-12: hemirm “v2.23 acute result .223 in large
quantities: being eaten each (12:3. 2322 {2210 occwion in partic-
ular thia 22113.3:“1 devo mod the entire 622125536 frwza the txila
of three 0:1?88. It 213.8 3312;223:012 to {=51 ca C-LJL: an 132.6

metabolism experiment. but on the morning. of December 5. 61:0

£59

33128 (103.11 in her 833111 3.33:.331219 13:3 1180. The 1.2.1:; re 13.1106
her Etf<:x.{",1., 2. 307.121", F1311 t :18 22233.0 to {jet 1:31.133?) 1.3.1” iii-ct 1.1.0
£01103.‘i-‘.;g (113;; 3. ..33265 use: Lance, elm-o 1:23;: mixed with a
stag ering, {gs-it. "9.1.139 353.3 3.33:: Yr; 311-17: 121 309333433 1131'
non-1:1 z: 3,) unite $2.0 real-m 33.8 04314336!- :30 3.1310 113.17.;

611;)..31031511tod 3.31131; (3.3“ 1333-11 2:133:10, 2:143:63 £131 or; 1110 form of

- \. ~ i 3 13- I J 3,: ..1\ ~,.. I ‘9 "
1103-13330 :53 1.3 .. .2.‘ 3 “-133”: bee-{15331. 2.3.0 (131-132.3311 0;. 3.313.933:

. ‘. . ‘1'." “ ‘ H ‘ ”‘1' "'1 "' ’ '. 3’ .t " Q' D:-
brzzn 1:328. 11:) Gucci; Du. tun (2-.-23.1313 .301" .-31r, 3.3:. on H.11]. El .

1935 :3 13103410, .350 ( 1181 233536.13, 3.3.3.32 t:;'.;3.n 0;; 131.18
calf while 63831133 13:11:.

133.0235. (3.) .-21‘58 tit-“(3n rm uhie m:.i"3.':1 iii-13361 to 55.3033: 13:15?
relation-3.1;) between 1.23.0 (1V,""?il‘:0d appetite (>de the 1.10063 cell
count.

Lee” ’58 3.3.1213 31.1312 heifer insiiicate that. the; factor in
91.15113 1313;? 12.3.3: pl‘QVC-flts (1.391.323.1331 fi'?_l3€3titi3 is 3123‘s {2013.12.10
to any 21121303312110 urgent in 1mm wart-1 mater. The mine-rem
00131533121011 in -. .23.} {321.08 .3225: 32.33 031.111) 0:. tag-2‘.";(3, {is well
as $2-9 are r3312: mi: ’23-):- 33 .131 (3 £337.18 33'.‘ ‘22..) 32.31'31‘ 2113110331 to
reliave 1:230 Ji3r...?te.. apfictifie far 12:12: and 513.343.333.39. It 18
8180111‘3-3313151‘ in 13333.) that f~31th rcgz,‘-1r;_;i$:?t—,d three heir
bells: '3 (1.21121 lg. 1:210 23.32: ’ of .4113. .; pict‘.1.1'8 thirty; 123.3 of

these 2....- :3 32-1.13 appears on :33320 (120) Of the "3 "-“"'3"“33"

(arlf 0.1::-

v

31 para bre' 11:31:: .cin 13.313. 0:21 f born Eist'az. her 118.13.;f'. ,
1333 2:} wed on the err-c: 1:31:33; 11: J 41:31:" 6, 19.311. :18 1T8 con-
tinmad on this expel-3i. 1:331:13 1131.11 1.3.8 (.3 “‘ “fill 13. 1934.
The MEL-3:; of 133.18 crlf before he was 3.3120031 on the czpsrizu-nt

03115183011133.1019 3.35.14, nixed {32's in and 331$ 118.3 L353. 1118

.. ' .. .. 1. ' .
cnpvrlacn1u1 ra-- coa:,711

-30d of 7Lile L;

Q

1;. crlcium cs Llonrte.

. ‘7 1" I .9 "‘7 A" " s ‘ D: . o . I7 ' '3‘ - - -. . .‘
£101“ 318333 4-1.. 30 21...; €3.13]. 5. -13: ‘11. -1‘. -..‘:_ '3 W131! Illfid EDI band LE .
.Q'I a ‘& 9“. Q . l . on .. "2 ‘ '7‘ ‘.4 .I_
fiQJRS Lug 0b.: stigma. f7’CICu o. hafllzzcmg1310d

 

cpgctito an; 1:11:2t11123 ;-c'”e naticnblc ah‘ t’e Lifidle of
.cbrtizzry. 313.26.. ‘3?1<7:1.71.7.1 11.77.21 :1 (:0123571371 1;: an 4:2:171221'3 1:,
f3113::0{i by $7.2) insular: 13.5. 311‘ 3.3271: 5.1121311. 13;. 11.1.1171: 13:; .37.
fine hundred 5117:1712 ..r. 111:; ":1" (15111113.- (221:3.3115-{3 (12211;; £16.de to the

'3‘ ‘ ‘4
J \g...

ration ad

I
‘1 ~5ng {7w --.-.'\ n
”41‘; y'j-‘ u a] ‘ can v‘Q‘M .

I: 1 :§:‘I‘i:1

n11 9 33 flu? crlf from

11. f 1"“ :- Cf‘lcfiilm 0:117 7:111. Le
-: 1‘); acid 311-317.. to. the

r -30 17.77.1111: 2' m: the: Calciggfl

carbznute. nn& :9 thu“e.o“o ' 1-)ntinard and corn Etar0h was
Ms 11“.;th 1:1 its .1309. The 8611131011212. 0171121733 armilable from

#23

orn atgrch so:

{‘4
*4.
£54

fillet-£2343 the dx‘Ur‘VC

- ~ J'-
sti)’:

. o ..-‘r n _ - 1 ‘1 ’
was o..1~ 31:11..)17123 311:1

51:33:11 15‘) . 1.3.

1:120:21 (3:111:33. 112131031

pne:*1nia wee in $11 grahahilizy the

fihe 83:3 3 of scate

93056 resulta indies‘

for denyeved enactite in all 08

L 4

fled to itkg7370Yu'e the
appetitfio

3111.11 80 111 531707.»?

labs .r pnexmfir.ie were found

emacispcd candision, but

Ite effect. however.
3851“?! £116. died on

t 1.51.8 ‘ 0.11ch that

pa

rate. 0.7.19. «3 of (.821'5‘...

{u

1:136
in the right

uhc ccfihfilic lakes were

re an: a care

(120 on he-

‘v - .‘ . . ‘¥-fl-\‘ ‘ I ‘ "-= l . " '&
hizod Laws 33; ~12 211.911n3 f"37 fl.prcvcd r ...1.0 are in a
‘1 ‘ . .. _, f‘ ‘ . ~ v . I A: .-s “‘7‘ . u no ,.- ‘- a... . .
V0.1? 10?: Btfitt} 01 It. 1: 53'. 211.3%.“ 03.18.11”? 31.73 ’ 1 ‘ i 1 (LC-1.. -. .8
.9 ‘ Q Q. 7 I . t . ‘ ’v p y 7 " '~. 0 .I ~ . (.I.. :. ,.. .' " .
0.; 9-3141. 1'). ”11:1 11%) .11:; 113‘, 1.5713,} b87331 €1.11} :3") (25:3 7~:.-..P.la-:.1 a..1» ..ziA.‘ {308 ,

in 111; 11‘013F.2..ll3

n '. ' 77. ..-,. a * '- t,_ -- 3 .- ; 7 .
.~. “a great} “(11:40.31 14 .1202 c 11 “3.31 “1.1m; no. 1&ng

- . “ .'_ . ..I‘ ~ . '2 . .u . l' ‘ ' .0 ‘ .. .- . ‘._ _ y‘-
L’LIQ 34.8000. 0;} 1,110 8-3152; 1-32.11. (1.1.1; :1... L. .'." i; )5. LU. :1-\} LLB

.

cumin nod on t. is 33021 zen: 1m 11 Lazr Garth June ..3. 13:42.
"ho In: inn cadciszou a; fibula u a. s 1 L ;;ntcd "LLh 0316*. zLd
and later '13:; myxzidlnml my; live;- z'l. Laviis were used

for bedding.

“ '1‘ i“.- 19 0‘ \I.‘ In": 'lu 1‘1‘d . ‘. " l ..1
“OUJC {.14.} O.) Aha-VI; J.'.".LC o -110 1.1. -(i;.;-§: C )C. .-’. 1.170; 0.".
m. —— fl

 

9333?.“ to be as 21’) hisuujx‘c. as u 0139:1333. ::~.“_.".;;L€; Lttr hU;3r’-‘1Vt2d
_. n.‘ .“c. ‘ -."."., . ..- ‘9‘ a- ' y In
{lilieultCo “31:0? 7533.0 Oa\-.‘l—L‘Jo& 15):; Lgu't’Lz.‘ 1-1 1‘48 2:“ 01 131‘ 1.0':llj
a Lax-.311. it; *..!‘...3 1": (1:23:21 0: 15:33 'Lr:->~r:,.;i;ze:1 Mm. 111 00.11111 231

following this c.;::n:3.e the 0:15 vac 3:12.121} with a cum of
aczzfso izxal‘igmzzlan and {Find 311229 5.3. 13:34. hex-72:9 Lge 01-3001; (If
the 11110313113110. cod liver oil 03113.11 be date‘sxirma.

pan teat. -3631 01:13:-.11133121‘5319 Chi-.3318 chef-r3 acrLL‘cic
of Lame 14111 cad were .3313. ..1u2:t naive urea-:2 0;: {jz_(=‘r.r§.ti~
in the PQQNMLJ. an: 8 £332.11 cha of enteritis were probably

the irazediate 0;:ch of 6-99311.

C"‘ u: Cr-‘ZS

”Ii-W ——~—“

A araéa Jersey Lcifer born ;pin 1. IJLL, vae L1>0Ld
on 122.9 c;:;>e..i:‘u;nt to 370110! in (19' 3'. This Lifer 1.98 1m 11 (3‘11;-
tinzzcd on this magazine-111: up to the ‘. :3 of :‘ri; H ‘ 3111:: t; a:

The retina v25 varied {2:071 $5.31 to ti‘ifi“: 8<=C'>Y‘-ih8 ‘30 $110 '00"

"T

Lavior of to; L1; and ~.-..:‘.31..a nil-a. vfiiizcfi 03'“- We? :11. W"
oddized cod liar all. Lon-0 110.:1‘. M119 'IC'il. $33711) 0i iron
ljhcgrr‘CILQfite. 111$; lff: '3L'1 3:11; Y::lf a-.. b:.rll v-(r: 3 $16.41 {11351319 the

.XPGI‘iraont. {having-3,9. were used for budding.

Rates and “ ervr‘ijaL. 6:1! C-35 8t“rted cri Ling
the n“Lbcr chant tn) m} the after aha was placed on the ew-
perlmunt. Solffier oxigized nor $30 uno;iai zed £013 of cod
livar all lessened her desire for fiOOfio Linea. according to
Thailer. flepre‘i‘ed apgetite is Caused by a deflLiLn-cy of 3:08-
;)horou8 Laue "eal fine fed in tLe for:n 0L E3cciL1 ease and bone
meal and lfiter as bone flnur. but.ncitLor relieved the ae-
pravcd ayyctite. Canecfinuntly cofl liver oil Lav aéLed to the I
ration in ufiditian to Lane 3251 n Lout relieving the dLseLLe.
Bone meal and cod liver oil was replaced by phosphate on
Lugast :5. 19:4. 1

hiortlj eftnr this 0E2.n::e 9L0 eviduucod :gagznme of

irritability by lol‘ing her tongue. Linea the depraved 2939-
tite boom a mute a’3riratcd the ration was cLsnged to rhole
milk and alfalfa meal on Lepzenbor a. Following this 02.1250
the general cgycsrance aha conditisn of‘the Lnimzl Lhnvcd im-
pr0V03tnt. but the depraved apgetite continued to grow more
acute. Therefore, L”rup of iron phosphatu was again eflded to
the ration on October 7. 19J4. Lfiile on this ration she was
placed on the mLtaLoliem czpcrimnnt for seven days, bCE11JLnP
December 8. During the metabolism p-riod tL e ae3araved gspatite
became so prannuncod that it was necessary to LOLp Lcr muzzled
to greV¢znt the eating of wood aha shavings. as soon 28 the
metabolism period was :iniehed her ration wee chnge to whole
milk and cue pound of wheat brain daily. The condition and
agpeerance at enco 5L33’;cd erLed inprovemz at and all signs of
depraved appetite were reduced to zero until abaut the Eidul.

or 33:02:. {at fills time the bi‘lin was; increased to two {mantis

63

deny, e113 up to the present fine no further evidence of a
depravity we been observed. At times 83.0 Size-e been econ
10111113 her SOIL-$110, aldeh- in «all probal.ility in a {E'ifii'aLIfutEtfl-
tion of irritability. i’hie condition 12 shoe-n by s; 910339
z'hiuh epyeers on page {121) of the emagdiz.

Contradictory ‘reeulte were 0133} ined from feeéing cod
liver 7:11. Both 131-10 oxidized and the mmsiiéiiz-zod forms of cod
liver oil 'gzroved to be of no benefit as a roifief for the
perversion "11' appetite. The failure of bone meal. syrup of
iron phosphate and alfalfa: mar-r1 to cure the dcprrsvefi epcetito
may h—zdiznve that the Gimme is coated by difierent uncer-
13‘1113; factors. Che regulte abstained from the f<a(',-ciim-> of the
51:131ffi. mes-1 were surprising and difficult to cxpltin, since
the factor carried in alfalfa Lazy should also be flown} in
r"1f:_..1:€a 2:10:31. which was eimply 131m gzowdcrefl green alfalfa
lerwee. Very favorable results were om: inod from the feeling
of wheat. bran. 221:; points to the pretence of a factor in when

bran that; r313 serve at: a cure for depraved ep::-etite.

_§F1f 0-37

5.32118 greée fielatein bull calf born 113:3 8. 13 44. tees
Placed on the expctimen 2.34;; 10, 19;.‘14. Ho Lee hen continued
on this. ez-cperieent up to the present $5.210. 53116 ration has
coneietefl of whole milk, 81133)]. :mnted with syrup 0:." iron phos-
gmete. :‘heflnge were used for homing.

petite

303m: one} observations. than the depraved up

 

was first evidenced syrup of iron pho:.;ng-te was cddefi to the

ration. (lonatijeetion resulted from the foefiing of syrup of

iron phoej>h.t:te. 8.11;: it. boos-me nec<zeest-.ry to feed neutral

paraffin 011 1113 a :2111‘311‘511’0 for nearly 1.110 111111131. Since that
time the colt hoe not been bothered to 911:; great; extent from
cox'xatipefiion. although the icons are 8.1111138 slightly more fire
than normal.

marked 13;: apt-91111 of depraved 11:1 etite 1:er never been
evidox‘. cod 11'" this (min-"l. olth. 1:11:11 00021110112113 after feeding
be 1111]. eat a fee: 3193111 13110 syrup of iron 31110111111110 11128

1111 :uoeuiozmhly 11111.11 :1 factor in :1revezztl;1g depraved upgetito.
Col! C-ZQ

n greoe Eioletein 111111 calf born its-my 11. 29.14, 1:23.13
placed on the exporrwnt at Itinotoon (11:31: of ego. lie 121.111 c011-
tinned on this. experiment 1111113.]. his death wocember at, 19.513.

The ration os'n111ietedmr:holo 13111:. flov era 0:: f: 11; 112.11: 31161
sodium (.1 10:11.0. Limvlnge were used for hedging}.

gloom: mind Q111311r1'n‘,1on6. Both flowers of." 1.1111151: 22nd

 

 

sodium-chloride foiled to (locum-11‘s the deoroveé (1:1 mtite and
the 1111121111 resorted to eating 6113111136, crib 1113 Me iéilllfiGI‘,
chewing hie tell. grittlng 11112 tooth en-o 221.1333 hie novel.

01]. Eocember 10. 19.34, he was plamd on a metaboliazm (12-13011:on
for a period of 8611211 6.1732 in order to deter: 1.1111 use crloiunl,
211111 phoroue £11111 nitrogen bola-wee.

9110 close after the completion of the moto‘u 111.1111 e1:-
Periocmt the (111': 1111-11 a slight convoldon or. fooclin 1: Lime.
follow-10d b; a second oozwuloion of short duredon on ”0011:1101?
2.... 1934. Rio 12-28 observed to he Very irritable 131161 nervous

on 90611211101: 2:3, and (11. ed in a cow 11111011 on uBCUIflbOr :35. 195.4.

Up'm port marten cili'mllmtieu m: 33.1119 1’11.Ii-313rl“17-.F££:8 17:21 re
fame. under the eyiccrdium and emoczrdim. 111011;, 1.3.1111 extreue
fatty degeneration of 11:-.1:- liver.

The eulgher was not a cure for depraved fipgetite in

this 1:111:11. 1. and did not prevent the occurrence of cmrmlaione.

9:91: CA-vrf)

 

A pure bred lloletcin bull 01:11 born June 12'... 19.44 was
placed on the experiment July 19. 19:34. He has b01111 continued
on this experiment up to the groccnt time. Before he can
placed on the GLmerincnt hie ration 0011.818th of whole milk,
mixed grain and alfalfa 11:13. 2111:. experieentrl ret ion consisted
of whole milk rupplezmnted wield raw 1221113006. .111 from the be-
ginning oi the exgerimmt. hearings were used for bedding.

notes and obzrervethzm. The raw linseed oil has not
prevented a depraved eppeisite for shavings. 1:01.161. heir end
more. {She 131111.112]. 11118 1211313158 been in good flesh 0111 his
coat 111:8 remained fairly click and {108333. He refuted his
feed for 1:10 first time on 11:11:11 13, 19:15, end was observed to
be Very c‘; if in gen and swollen in the Joints. (1m; 1m1drcd
ee‘eic centimeters of rev: linseed oil, EIVCII ee :1 crouch,
brought about recovery. The 011 1:18 2512111 fed in the milk
as a pert of the razion. Ho 81-5113 of depraved appetite more
31211115083011 (:1 1.11,; 1111161 breakdown. It is interesting to 11138
that just before this disturbance tL-e calf wee 151101-1113 ammo].
desire. which bordered closely onto 11:-1.:-11.1.131rxaie.

the results with thie 01.11! meicme that rev: lint-cad

011 has no effect upon depreved appetize-

86

28;: C-Sé

This grade 30188818 hniior erlf born 73(“”u 11. lJQé,
2988;215:0021 041 the 8:8 "3 1181-113 111192811”. 16, 1344. "3.2012388 0311-
tlnuod on 2818 ex 2302 31:28: 88311 1.8r 80:28 Bavogbcr L7. 1388.
Ihe rasiou 0:188183 d 02 88010 milk, 889,18388885 8138 uoutrrl

percffin oil. TLBViuge term 8805 for hedging.

30308 fififi n 3:8r"r‘1388. the remained nararl thr0838-

 

out the experiment. r 38 the 880893138 of a £88 hard breathing

attacks, Cfldfiea in L11 probaLilit; b; the 9:88:888 of a g31tar.
The 821133731 :3 111288 38.1 113 81,913 33.? depraved e 9; utito while on
the cxnurinnnt. U8 Kavenber ;a. 1324 the etlf 288 securing
and refused to out. fho 8188 the {3110 in: day in e conxm1113..

:2088 of 8L8

" ".

‘U

.A.

U908 9083 832383 03831883138 manuraus £d"
pericsrfiiun. along nlnh fiflhufiiaflfi of the r3888 and the flisgern
to :80 88118 of the tLarecic c: 2‘89 were 27:88. Lifiuee
ho2or 88.88 Vile {3:188 on the ru.3 azn 888 in the ‘Lwor 810 08.1%
8n5 81885 the entire 1883 an 02 $80 8 18-1 031138. A partial

$10218 oLcsruc: inn or: used by em: GSlee 28228 of cannccnive
tissue a~9 Lava been tlo 131cfiifita CLRCO of 58838.

The neutral 98182218 011 may have preventeé the
appearance of the depraved 899atite, but in 811 probability
the c It 5185 of convuL iOuB haf3rc £88 dcpra 05 e9sotite had

time to develop.

02;! 6-56

A grade fiolstain bull Gil! barn Sagteabar 3. 1934. was

Placed on the experiment.at niue days of age. fie was continued

67

on th 13 oz: 1.5nt until his death zebru22y 14 . 1335. She
ratio was trried from time to Lima c'c r‘ing to the behavior
of the crlf. Thole mllL, shim milk, c1rn, orte, oat hulle,
bone flour nufi cod liver 911 were fed duriny the c: 6“"tLto
thvinge ware used for befifiing.

L2L££LSWfiL£ELPYV" 10n;;. T a calf was fed an rhole
milk alone until hiptewber 33, 1934, when he was cgsnged to
akin miln. corn and 0232. 1Le fire: indicrtiane vi a do-
prcvcd ap1etito became evident about 2L0 midple n: hovcnbcr.
Vince the aniqyl egowed a prefrrenco for oats th corn was
removed fran the ratian nna 2:13 milk eu1L1c' mc2t29d cane
clone constituted the diet until January 13, 1335. TLC do-
praved flijtitO continued to iuo case in intensity and out
hulls were nfided to the raaiou an J Ruhr: 16. 1025. The
aduitiontl r32312a: in yhe out nulls. however. had no ef;oct
upon the dcpzcveu avwetite. Liter the calf2 ad a {light con-
vuleian on Jnuurry 31. 1945, the outs axfl Ont hulls were re-
maved firm: the ration. 2:116. 02 10 pound of 1220:} b: an #238 enh-
etitated in thi: place. She calf became garalizod in the
roar anrtcru follo~1n3 a Vary violent conxwll ion t£'~iuh
occurred on Januaty 26, 192'. During the convulsion the
animal became bloated and ten cubic centimcficra of forralde-
hyde 188 given aa a drzn2ch o relieve tLe blozt. Ln attuzp
was made to rulieve the pare13zed Candi ion by feeding cod
liver ail and Lona meclg Eha animal grnguslly EYGW “0330:.
hO‘FEVfEr. and dim}: February 141-. 121215.

Upon post norteu2exr.11nnt ion hcrg1r: Lego: more ioznd

1n fihe mucaea of the urinary bladder. along with n HGIOEB

68
arena of ruifcning. Che lungu thawed a 83x11 an) nt of rod
he 15313021031 in 1.34:: right cmx‘iluu 1012:}, mi; canssidczrnbla can-

BOE'JOII ill the (11‘; 1"12".? l'il‘ui, :..101;::‘ fiité- It:):‘;(; (,G;;;:j;"f",1)11 of; 1,116

k ' x

6‘
H

=Fill. The intci'cE‘Lin3 35.1“; of the mat-35mg was a raj]. ornatirm
of the first lumbar verbcbrau, vhich 3r130630§ into the 9313:1
ca.L;1, e“g“ 'zin; conuiderabla ;:vs:u*. u,an the Sylutl caré,

ch use almast 0111: arm: a at this poigt. The atropgiod
0:135:1th of the 633.31 cord no climbt econaute for "132:0 petal; '::.r.<1
condition of the rc:r flum‘tcrfi.
22119:: results at 1:38:33 316.101.:13 t2; '3 dr':jfz.‘r~'..'c(1 appetite

May be prndicea c3 rye 11: in Ln uniual o tLiJ n 1)., corn and

cat as on 21319 '%i ‘ 121019. She r1231rge in.thc ort hulls
fiid not from; i; or relieve tie ficgra‘m—d cpl-2033.130. air. in 0:11:11“:

121213 1‘) ..0 age 1;}; e 1.; work: :t‘. factor 2,121; c was depraved
a),0.1.o 2L9 bran in this case was nut Tc -& for a sufficient
lirzlgfgth of time to enable any maelueiéus to be drag-:1. It is
not uu:prisin3 tLut the cod i;ver oil and bane nail fiié not

relieve tl.o paralysed (1312611 .3.-m. thick; was caused h, the

flay-:23 0;: the 9:11:21 card.

 

These gram) 3301830171 heiforb ‘tlvee taro If icon (2le a1;,
+-' ‘F ‘. - 4" J. 11% 4 1 '9 a". 1‘! (‘3‘ \?! , .""’ I‘ '1 57" f w "
~10 sue a...) no .3.)“ {331:hb 0.; “be. ..he (“31.4 la .mo 10:: .hole
:11 2; 3:1,)” 107331131 1': 1 £1 Ctlcizm Curuow to 2.11:1 coal in}: 011
(luring; the “first six wants. .gt this time the razlon nae 02:24:50;
to skim milk. calcium madman-:39. cod Zivcr 2:11. corn. oxte and
alf:.:lfa in}; :2 ich U5; 8 (3,111.- ..‘md :‘uil 1.2.9 calms-run 357m:
mmtha of up a. C-S? £315; b~$9 were then {almond on :kin milk.

F'

com. oats and ms: 52:10:31sz pm: uh! ta. 1‘"). ile C-.>5 an d ~~. ".8 more

(:9

fed only 311$ milk corn and 0333. ht six mxnahs of: a all
in! animals: wet-‘0 placed on 8 141285-]. “211).. of corn 8112.59
and a grain "5:13:15 .330 consisting of three prrts com, mm part
oats 3.21.1 one z‘II'r cottrm 908.1 mm]... 111 add 5.1011 to 1:1» b31331
razion 13-37 222261 “-73 were: given three I). r0331: 313.3113. (:31 um
:)329:‘~:.)hs'te.. "fr-.9511: etrnw Yi‘fiP. used for bedding.

Hates and cheer" . 21:10:18. $312380 22111.11: I‘CTI'TiflGd name
in every tnsjaect. and showed an perversion of uptetite until
the) 511:?1fa 1233 was to Ioved from the main... Shortly after
1:3 .is c‘mnge was :3.-do the 3111:3318 developed an appetite is):
mod £121.11 shavings. '33‘6 01'1'2‘17 115; f0: 1303.1 in {-55 is 11 15323310.}.
by a 31 3111‘0, 3:12:10}: 313:7 be 10212.11 DI. page (1:32, ) of 1.110 .13) 3.1.1121.

neither the magnesium .-i2o:':phata nor the 1332151110
carried in the 35.1339 3.2113.- wheat eurnw reliu'c‘ea 1.3.3 depraved
apmtite. $31.08.) 2222132313 were receiving an 8(10f12t8 ram-an 11th
the exception of the right guzzlity of $0.1Fh5116, .1101“. again
ermhue 25.38 the injurtrrnco of 132.0 £30 3801‘ carried in 3.1.211 cured

!\,-.“
1“. ‘1.

field 03:33:95: 1. 53.. S {III-51 4

 

:3.-19H) 031W .3 1 are .11 pure bred Jersey cz‘11ves raised

on 3 ..arm n er .-aet 13:21.- 1.23. Calves land 3 were np-~r0: .25.. ..1;
m3 3.17.2.3!) my son clay:- of age and CI... 13222 2 and 4. were £31.: £11.
one—11.3.1! 171)}."118 of 2230. '3. my 3.11 fieinnpad a depraved 0.31.12.31.26
on a ration of no]. 5.1,8119119. 112;; 3.12.". 3. gr: 5.11 mixture c.22-

fT-osad In“! mmrl parts of 11: .5006 oil 1363.1, 32'.) ‘tnd 11:10:; and

V

wheat b33911. TEL-€23 I711 had an an 61.1"!) far "006. and had been

chew'ng 1:210 1502223213.- 01’ the p 21 12.2.5. 'I 21303:. 15"...) 03:21.01: 9.1220

70

etutofl that the; lad bean cut-ng 82:39, Ingfitnfii£hfl"Ia from
time 30 $113. Lofl liver 011 $22 ird to ELLSG uni £16 at the
rate of tr. (MLI-LALO c L c ccuzi:vetc'e I r d:;. ‘lthin fix-
teen.dc .5 he as Jud ctrctite .afl entixdly LLsaaoaxred in

all fDII Ufil?elo

plnin uLy 3L9 defravea a patitn deleogaa. Blond pictiree 0f
tnceo uniazle showed that the cod liver all ,roiuccd no
fifljrcclfible chanafl in 330 bload cplcinm Lug phocgharoue. £1-

tho;;h it 6 :‘a3 to rL 116% the new” rod up stifle.

TEVGa “)eti€;~ e Unfi 9r flrrfl u0"’*i“n

w

231
:5

DegrL red ey‘ctz ta was reportea rnru; érlry catfilo
in.Tuscola Co ntg, iichigcn, L: the co Lt: agric;ltur$1 agcnt.
Er. 331-1In visited this sectian on July 13, 1334 ald studied
the annuitizna Iznucr th:ich Gehra"cd a; . shite occurred on
farm; :1, 3 and C. :L st of the core at tint-Le Irrrss exhibized
a c; a"ing for rags, vssac, Lanes. (:1 eLc, an: <9 1a leave
g3=d Incuuro in cracr to chew those ECtCriilfio the depraved
up etite aeuncd to I:2cxz:11 only in the prairie lanfi.region
and mat in 60021-51113 who: a $101.21ch x2: ‘10 "EIU -17 cow's-rod by
timber. It was rcparfied that Tflfit of the affeched cattle
had newclnpe the depraved appetite in the 09:13 {firing after
being Lurnud on pasture. Cows in milk seated t9 be the mare

EnsueptiLle lhiln dry 0018 WUEO not aifcc,edo

A mixture 00212115131115; of finely 2.0“” 11:: stone rocL,
twat-3e, 9:1: and cos. 11:-er 0117.38 left? :2 _,.1_ ca: 3.
A mi;{ Lure of bone meal, acid phosphite, rrlt aué cad liver ail

'38 left on farm 9. Che owners of these cattle pro“?9ea to

feed. t1.m“13:-L12irce, aaufirfiing ti tic 1126031338 gi”cn b3
21:. [1115.1 .311.

11:1:t1re 82: 10 was taken.fran the 1131110, thidl
a:lL.i€Zfld .1211: of Canufi1n h‘u; ng23. L E11111: 811 la

.. 4 ‘ 1‘ . n - ‘ 1‘ “rm-‘2... . .. 1
12nd 9-110 main]. 11".} . 1'31; 11w”; w}? 03.13341 ’31 1....6‘. Lavish-1,7711 ultflufl

'V'- "rug ’~ . "1‘

9.1112363 2:831:13. 11.1.11“: .23.; 3.11:5 1.4.. 1“.) C.:‘J.::Cfi L: 31-9 1.3:"
riigdt “ta L133 {hagiuzr" f3: calcium, 3h:.*har.ue and iron.
29:1128
1.2....3. :actzr; Yam 9 7‘28‘3111‘6

{ 3:0 d1).-‘1:"....1);;£1‘;130 ) (113133" :51 appetite)

02.1.; l‘L} 01:13.3 0 o o o o o o o a o 0 01.3113 OQE'7;:J

1301100000000.00.000.009.00034‘4 Codi-.11.;
0' q .. -' .4
311011311 ‘Jl’OLLSo... o a... no a 003011-113 0": ,9

A 821.31 trip an: mafia 1. 2123113 Cavity on September
13. 1344. and furgs 3, 3. Co B and E were Y11110d. It

. \_ ‘bt - w ‘ , mfi‘ .—. Q~., . »‘~, 9 ." _ ‘ If Q 4- .1; ‘ . « __' \ v
13133 unnf buyfglua 5311.1.“ “an 139611131 nn-Lg dairy Lhi1fle

*‘u ‘. '1 -' ‘d ‘I’Jn * I_ \ V'f C '2 u. . . ‘ ‘ on‘
on .Le'o ft'me m. in; “L3 &1r .3 sad earl; :1imcr, b1” Ctflut
' '~ $ ‘1‘! ‘1- 1- *' - - ~. A Oaw 7-. - . -‘ ~ . “ -. 0 4 “ 9. "‘
“"L£‘l€ " ALI-L I tfiC C;-'Il‘./L.u.91 c I n—isliz CZC-A-unf»: «5' Lug: ”~51. '31“

fa~mcre re nrtafi 315% thy 211 0L10rvcfi theta same caniitiyus
in ;re: 1012 3 are.

218““:1 23 1.3.8350 33.0 cows 24:31 received cad ch-r {111. 1:21.}:-
EEG. £113 £31 11313319 ruck. rhwmc§ no cvigc.cc of’d93”arcd
63';xetite. any 1111113t (one so :11 3 the first of -nvust.

A cor on farm C bad xLib ‘Cfl a 80v;rc ra?ing far
fiLnorncl 311139 123 cu$1;.1; 01:91, and hta nnt 0L.1p1¢cd tie
E“W”‘.as Eince than, the first .i'Lugast t» which time oats
Rafi been aided :0 hcr r‘t :11.

LJLHHIC in h1-rd 1135 had been receiving limest.ne

rock. tankrge, 621$ and cod liver oil had coated to chew voad.

but. 83.7.11]. bid a c 7277.15.13 for house. Chess 17.211.73.13 3:25.42 still
on good pasture but mm not receiving a grain eu.;:;:le.i-:e.nt.
2‘10 Hangers it ‘1 the b81771] 1:731:er theee 0317.8 i188. born stabled
during the early 3357:: of 61352731, 11nd ”vein (7.72.67.7le 2.0 file tax--
tent that one of 317.0 83.3 in 11 17.02213 7 .s 5 11:75:15? devoured for

3 5.1833309 of +370 to 7.7.1 7.1790 f at. Liv-mermm specimnu of sum-.8
and boards 711011 13rd bean ales-2d e: 13...: in ffim 53.73.1213 were
mllccfsod iron the 7)!7€€;7.117(28 on this 5717121. L’217‘.Iista§:n‘z.lo

mid 2109 was :1‘3 mt; which 5.71137 ed that the 007.78 )ec'i been 02231::
3:717:88 we. 023.017.75.213 borrde 1117;027:231:rage-ably.

Holstein 1147176 on F3133 17-? we a in fond 751357}: at the
the of this visit, and according: to the owner and comm-7,77
eggent three mingle 17.12:”. 11.7317. ez-jlibitod e depraved 17.33.3013)". 6 for
11633115? 51:: Iva-01.79. $10130 (wiggle 27:36. dc:7v::137;>ecl a r::a:'.-cd (10-

praved up 301:5. we on street clover 1:: stare in 17.21:: 81:17:.ng cm}
earl-7,? 871771.731, 7.311911 the 1352515711170 co.--etit:7:.te<1 tie entire ratirm.
About August first 17.13.»: sweet clover 9917.77.39 ':‘-'!".-8 £711 161' maimed
71:11 a grain . rm; ion. Samples of the sweet clover pasture were
tréum in the 877.007.11.721“ 12103:: £217.71 Hood ctngjne. "no succulent
stage reprceentgd tm ”nature that those n:2i:.1:19 recurred at
the time the flogbrr2v.,d agnotiw dchlOpcd. 37.21113 the: bloom and
seed 830- 08 17973170.; sited the pasture the 121111-1818 rece ivcd at
the 31533 the doumvcd agjmtira flienp~77‘-cm7ed. T7310 350110771113
table 83.017733 the percent caluimn and 1:1;0:;;;7:E7:31707.Le of these 133.1700
stages, 5.101713 with the 9311111152 of each pmtaro needed to Iain-fire:
the crlcitm .11}. 73110833101318 :0 31117973911113 9‘! a nine haired and
thirty-five pound cow 3270:57101113 thirty-fix pounds .37.: awn-=50

‘1'; 6.131137.

73

 

 

 

 

 

 

oamuommw: - , t
I: a. 5.33: o# a: 5 mmmw .0 302.0 coon
. Unoflflfl ? ?| ”Hui
CHHde‘Md U.’dwhnu9fl ”Nd QM ‘WMFOO ommfioo a 80H”
333a... 33"“ 03 em 9.3.0 Rag afiasaoam
In? 15* ' i 1 r i I

:3. i? is . n a «w M
maaouvsu» too .2“ mam mo IItlkPLm »

axucéom augmeuuancon A a so sacs cacao uc eaaaadcd chapanm

an unuu@c unsuccu us .ana

til

 

 

 

 

 

Gazassm uo>0~0 uqcsc

no cemxum ucem was acada

wasnaoofim no accvaeo ezouozucozu uc¢ aaaonao_m=«=cnm 04233

 

 

F:

. L I
£13“
£301
am

8‘7;

N3
g3

On.0ctnbor 1:. 19m4. a fiolstcin Hard on farm P tget
had becn.€ui;oring frog depraved cpgczite daring tLe £1330!
nonzha. was Visitué. Pasture can iated of mixed clover Lufi
blue erase. Sheee an nrls were producing farty to e;xty
pounds of milk a day in Lay ung th 50 £111.039d tit“ the
depraved appetite dronpcd in a Very rhsrt time to zvclve to
twenty pounds of milk dri j, thllc 82111 on ;oad pasture.
Before being turned on pasture 1n the a ring fiheee QuiJfle
had received a ratian hirh in calcium, but cagpxraZLVLly low
in psocaharoue. T o depraved epgctito canned shunt “ugact
'iret. at vhich time the pasture was sugg ozeuted tith grpin.

"a

2asturo and 2011 samples rare tcncn on farms A, B, n.

3 and E where depraved a: e, to prevailed. Sinilrr pcetur
anm}1ea were also collectoa on X. E. C. form an: on Texas

F and 3 where depraved n,‘etite J88 not prOVulant. 2L0

r uulta of the anelyeie of fihoeo samples for calcium and
phonphornus along with the pounas of such prctur nccdod to
meet the orlciam and phosphorous re uirenenta of a nigo handled

and thirty-five pound con producing thirty six pounds of

average silk daily apqesre in the folloving tablce.

75

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

493... a # } i: x 4 i
fichsuuou can
narrficd vaans
filxfla amazéfiu Oh I I ammo. muoH 3388! ill! b
r GN#uu acma r u 4:
assess .ouapmsu
.338 39$ 02 wm «moo. owé 3.3.0 _ 2.3.0 a
Gazpcam a dam t, t 1!r J:
oaflncuw>oHo mad 5: 3 t mmmm.o smmn.o a
non“. 11 t 14
9159.51; Ha.“ ...«a 5 .
Io.u< 00>:upea nwm om nowo. an.: mum:.o h:nn.0 4
moéafi: .: r ?
suav-ou5aaaa
5 9....“ch on 2mm «3 I I 9530.0 913.0 0
l1
NW0“
in: :5” n underway; A
too .fi no .3 3:82 i - L
I032»: a d 8 v.52 3

sundae.“

60609» 830.3; 8 .53

 

 

 

"new no edemaaa<

23.8 no 3:351“ 9:598

 

IIIIII

.anaabonm 3309: vogupen 8:5: ooaamfié ouzuesfi cc.» «new we 380.80 a a 8 $5.58» 0.51."

n I& 1' *‘II.“ “‘4“ I.||‘
n «Launrc w. c. {.10

 

 

76

 

 

 

 

 

 

 

 

 

 

 

 

 

 

v
naexfip 9w: edge:- donc Omd m: m:w.o #OhMoO A I
Ouaaosad Wabgumcu £hW1 > rt! 4
aumxa 9r: mHLfigu cox; ndd mm mmmmo.o nwmm.o h
opaaoaué wm>fihwov on It!
hash no uufim hauéo mud on ocwo.o nomm.o .O.w.a
coxdw can... cup—5E r
ad 3% 11 :1
:33 .9”; an m: «:6 m % do n A % so %
ton; soc .2“ aha no azafi }-
ughdSQQ neudzveu a a do am:2 o» :1.+ ousuoam
_ fiance: aucuaga we .unq Adam uc u«a»a¢:< undue no auc>neai

opaooua< couguacn o: as; cuss» cueg; eouzagua

. mean: a so

77

0 ul: 8 9f Y: t: 51121~y «at

- - _v “..1—wow-..“

four cnlvca Euf.011ng fr03 u"1'v0d ngzza=tiae xero
per\ d on a mutabolhsm GXj‘hEIi mm; 1:; order to (tutm'raino the
calcium. pizngzharoufi, rind nitrogen balzuzfias.

Calf v.18 did not exhibit a girgcd 'cpya?cd apggtire
during she .ouaudliau p riod and Coal. tn an1331 KL :3 dc-
prGVud uzpetito “83 $120 marbud daring tCa nctubfiliam a}-
pcri .cnt, taro bath in pa: ;t:vo nitra an, e in rut pgog-
yharouc bnlxucce. firevioue to ant m.taznl£vm yLzriau t a
letter hrd exhibited a dupKGVud spyctize 131:.

Eha depraved 59303136 of Csli 6-35 flaring the
metaboliam echrincut was var" flirted on& it vae Leecercry
to keep the c'lf mangled in order t-3 preVCht tha gating of
$006 and ehnvin;e. fieVertheleEB she was also in a potitive
csloiun. pharnhnroue rnd nitragcn balgnce.

Crlf C-.8 rho chowcd n mvruod écgrcved rpgoni.e for
mood throu hon; t e eutire Bevan fisy a ::a in u go itixe
nitrogen. Orlcium an; phOfiJhflYOJE balrmcce Sue entire perioa.

$39 dnily cslciuz. pun phaxoaa tn: nitroxcn balan as
along with the average bainuuo far tLe motnuolirm a-riod fbr
each calf E) cars Buparstuly for cabh CLIf in the rollwrina

tables.

78

no.0m ecznaflm agfiumaa

 

Hom.m o .MHH mn¢.mm ow.mm ~mx.smn :cfi.m mm~.m mm:.aWH :v\aa\ma
www.mo mNm.oo www.mm hmo.:x Nz:.:c :u~.m mo~.m we:.mnm :m\om\ma
mnm.~a www.mu ~mw.:n you. 2 md:.nfi< zmfl.m mm~.m ums.wm m\mgxma
30m.» mp”. a” wzm.~m ~ac.m: 5.3. :9 :wfl.m Lmn.¢ mm:.mflfl :m\mfl\ma
mno.: mmz.ofla aam.ah “$9.9: ~m:.:xa 2w”.m mo~.m mms.m- :m\~fl\ma
ins.”m n:a.m ann.nn NNm. N: ~u:.:ma _ :cH.m mm~.m was. a” :U\mfl\ma
o~o.~m Hmm.~w m¢n.mn as,.m: ~m:.:m~ :wfl.m mm~.m mm:.mfla :m\m~\ma
gonnaam cause flavoa cadub cocoa oxsucu "such xxposdh neopxuom caguc oaam

' It'll! .rll}!

can” a“ tow

’4

cofiasu r so auansgg< vs>en.msn vrza4 H:a.c~m mi: Haaux<
MAID NHJD no ccccfififim Suficdfiog Cc:.m~:ukc..r...»:.fla gscmnvhuum maukozm
95390 c« :cmnvhvuz

H .0: zer<h

79

mama. AH acqqu4._.m omrum><

m?am.m

mcaa.oa
mwnw. a
mums.

8 Crudm

Maxn. go

nymoa@

amuse Have»

A. mmflfi .. w. 3.
Tap Tm},
ficxm.wm
socc.mm
Hmm~.oo
0”. Ca . OH

www.mn

czaua

I’ll,

2: x ,

jcnh.ma
wfl m.-
w:m~.wu
arcs. ma
ommm.-

uwmx.mu

’ I,

accch

l'

hmnn.:~
Nov :3 . «N.
mmm~.mc

MJH.a~
~m3<.,~
fimafl.v~
Nmmn.m~

oxrucH #fipCB

Barukc C." Dcmwnn

UCSCHaZGO H .0:

:<:.H
0:6 :.H
0 Jr.» J 0 fl

xxpceda

H»H.M
nwa.a
www.n
aha.w
~n~.m
«ha.m
nmfl.m

il"

amcutpoa

E

machinuhw
m;::.~u
mm...c..mu
:«n;.~c
wcmz.~c

mama..~m.

it'll

cutuu

:m\fln\mfl
+r..\9.,\ma
:u\mfl\rfl
:m\m~\na
:m\~H\mH
.3.. \mH\mH
:axma\aa

Guam

rlrfl'

80

I .. I... .. J. «
\..i.... q\ l

nmA4¢.m

u\\.?

ow,
604:4.7
044:6.n

Ovumfi.m

mnm.:

4 4.54

fit [.4 .o

wwnAm.6
oAcAa.a

K3.o

N49

woch.~

wAAAo.

mmuAA.m

cnr.Adm mu.u. .><

z. A 0A
mAAA.w
me$.m
oomn.o
oa-.o
o «4.6
ncA..m

:nmu.ma

cc3H.:H

mmmm.AA
Ku4+.AA
AmeK.mA
Jfl3\o.§

mmca.A

.kv...» .. .
0‘“... ”snaa

aL-I...
orcrfa.

couAs.A

Amwo.m
AmA6. m

Aon

Anao.a

HA4. 3.4.

L» r.

Amao.m

Ammo.n

mnww.
A

”Imnln~ O

mme.

b

. C
C a.

mmAm.
mmnw.
mmum.

wmA¢.A
mwAw.~
EA. .0
mwAm.~
nwAm.~
mmAc.A
mwAw.~

:u\am\wa
:u\mu\mA
Au\mA\AA

.m4mA4mA
:m\~A\mA
:m4mA4mA
:u\mA\mA

 

Ill

..m OM98

750.“.

pooch

extaCH .9503

. C...»

539:9

5.3th Cd 0:0

“Essa €50

HQ$<B

uwcuzuok

a «duo

cage

81.

31.. as. fin 095.42
A 0..-...0...
9. To ..A. a...

1. . ..BA gin
AKHN OFOH 0:35 ..\4

mAAm.nm
0.....10 0 Wm.
046m.m:

CNN...mL

04.30 AAaAh ocwun

a... so ha...» 0...

Halo u... U

mAmm.mm
mm... mm mm“

cam.c;
cAmA.~n

koA.om
043:.wm

ococh

ruuumAA:

cc>Au .96 v: av: AA:

HH .0...

Amm.wAA m»m.:

Hoszu mKA._.......
Amm.oAA mpa.
Aom.mAA m~m.:

H963" 2b...“

me.:

me.:

1m. .cAA
Amm.mAA

gafuuH Manon. biota.

v.3 3 2.2 5:...»

LA... «EAfiABAMAS c9925....aAE “ASA... Esnoio 3.5....

5 .m.......uu p A: _
aqfiqh

scwoo
sow . MA

SC- 3
:Cwuc

aficwfiuog

.8.» A2 MAASFAAAu

N... ..x. H ....<

.mom \tA\ a
mAn.mnA 454AA\CA

4A....A Aa4y~4nA

DI
_\

n.

AA.ncA :axAAxaA
S.. .A :.40A..A
A :n\m\uA
mAx.ch :M\m\m

5 duo

.-..S. 4S

.\
3.2...
cf“ Q ..l.\k... C

$.40@.0
ma4mo.4m
w.w+m.1
QAmw.0m
mm.~m.n

009...“...5

O ..vfiw..m. o 4%

. .\ O
AMO...wG.mm
mm.no.mq

amaze Anaoa

maafi.ma no; .+m cm:u.><

00.4w.cA
wmne~.cu

Griffinu-te
.. -2

a... 3....HH
AAommw.mA
A. 1.53%:

chmS.mH

eaflun

m»cw.wn
40S4.m-
On? .3
omm~.mm

MW“ AAUotna

“cf.

o¢.$.~»

it}? In

acecm

232.5“ ACACU

0x332; 2.938

wwsfl.a
$41.5;

inwamA $4.~.1.n.fi
saro.me w.§ .H
:mwm.wm wwrfl

AAHHHmowC w... ...r M

:Hma.ww mwma

A...A...Ctum

Queue an moan

HH .0: kumqh

mmnfl.m
wwww.”
--.“.n
Cuba.»

um~n.n

ate u: a Ca»

..Awnm . 1.1%
up A _ .
¢ur .dc

dmrm.zfl
Amm...m.AAc
Amnm.+u
... Mani; U

:wnm.3m

cAauc

:a4xa4;a
$.4mA4ua
324xH4ya
:u4afi4uu
Am\od\ma
rm.o4ufl
:m\w\ma

0 “fig

85

cagasm omega Hague

o.~\..ar
r.anu. ..__

:~m~m.«:

éqemu.~o
$:nbmofir

:wam.mw

. ‘r’ ....
.‘\ at M

. :M @053.“ ... 2 emf.“

:me3.
...w..@ “No

cad“:

now. 0:

mmu.na
$1109..
osm.o»
uxm.ww
m h. w:
an; . .8

}l

>1

mm~.ww

“WW-mu...

.... .. . J.
CI\.(I h

mnH.H
2mm.”

”:9.
wma.m
amm.a

559% 33:23 H.338 Recs»

“5:: .3

mm

.C:

wm~.a
mH~.m
wfl~.n
man. J
”a .

:nw..w .
in. w... .m .

in, ..wC o

4‘... ...

m«~.u

hauC£dh

at. MO Cd 90

ugwav

accuruca

:skm.+
mam H . em
mmqfl

m. m2 H . 4w
mm$a.:w

add—ho

fifl\flH\KH

:s\na\mn

\naxaa
...xfaa\r H
:a\n~\ma
¢m\m\m~

”\m\ma

adage

84

whim .~ no .yfi3.a 9:4 c><
a33.3o enofl.m; cyan.wa whaw.:~ mano.aw own3.ws :m\:fl\oa

o
mNHm.fld o-:m.oe ca 9.”: cumm.wfl mrfim.flfi mmyfi.em ccmu.33 %..‘.H\ a
m33..m m3 3.N3 am n.:¢ o3ms.mm .:50. on mcmm.wm mmmm.m: :u\.n\aa

.“ 9 wf\(\
nhww.afl mm a.ma mHH.c; mm-.. mfl Hmflm.o~ “a .mu mflh. x: :3\HH\3H
9...... ...: mm. 0.10 mi)?“ ”it...“ wamméc om... ... ...”..u w“. 1.. .. .2 ..H....\c._.\....m
m.na.nfl mxm.fim mua.m: nmm.oH :ws. 5 mega.:m ¢m~.m: :u\0\ma

an:.~ amn.am “no.3: 0mm. m www.o~ m-. u m:c.. :n\w\aa

confidrm ovuso Haney eddy: coach oxraCH «rank oe>3cg awaeua< xaaa 003a

’ I, [It
i, I'D 1'
I

.mdoa-g.:c:. mtfi Ezflca.c ca :nwg unennprurgacc :cautu a co
m.u..._.~.n...3..x: ..E: mfg “3.... “.33“ 9”,. :u ...... “.63...." .....U ml. 9,...“ 4... "3.x Hr ... «dd
mate .3 o M... 5:32;. ....m riff... .325 1:? s: n .10 .:._3w.....uu2u m: E can

3......”0 an arm. 3.5:...

HHH .62 “95B.

~4C.nm.
«03.na
~da.~m
m2~.ng

unc.nm

\o
. \
5x.

0
[u

m
Q
..1-:-
0
Ln

m3 4 OH
0 o. 44
340.44

tau..
nwc.w

mnauo

mNNA.H 3943M3m 3.3u33<

HAm.¢~
H¢A.H~
n12.9n
mmfl.m4
m3~.n~

kiwi..."

uAmw.ma

: ;:,.A.m.
mmm~.~u
mw~a.na

ablnwmw.fifl H0

.\ 4‘

mu3m.~m
wmmc.wm

1‘!

sneak oxsuun Hausa

kill

p.444.

uxzzupzco

mac.
mac.

«3.
on.
wAA.
mat.
mac.

I’l

anam

m n

HHH

mxw.

r};

:0kH

.om pnmqa

a O>$cd d.“ H3NH¢

it

man .4
m ~.c
A ~.m
:3 .c
mnw.m
ms... . -

fidwoa

Gib

by;

I,

NTEMAoed
admo.mw
w¢Hm.cx
mnew.mn
mmcwawm
$44.. \0 ......

mamroma

xfluu

4‘ {4|

33\3fl\m~
$m\m4\mn
3m\u4\ma
+m\aa\ma
zm\04\ma
:m\0\m~
:m\w\m

09:0

Ad
mnwozr wo...§..7.. .. :L .3. .
N:Nfl.ma am p.03 mprfl . m~n3.oq anhm.»n :mnw. mJG. mire. m m.om Hec.WH ¢ £H\(
2.m~.x www.mw o nwa. onm.w3 :.~c.wm HaNm. mix. mafia. o ¢.mm man.nfi :c3na\r
mma¢.a: :m~¢.mm aimam. m~3.mm mgmc.:m syn”. ago. m3po. . offl.mh mam.xa :m\aa\ma
mu~.m :of.~4 3:93 . was .N: n hm.wm 3 My. Lxc. nine. m»m.mn ”mm.¢a :m\flfl\m

\ - 1

+3.“- wwhfic.m¢ mummfi. ~wa¢.¢: fimfln.c: o~mc. 3:0. nxnc. ~Hc.am .um. a ¢«\ow\m~
3+uuu.u sand.¢: ea.” . 33m.a¢ 53?.3w ~mm3. awn. awnc. wan.an 3mn.MH ¢m\m\ma

wanmu.s mvmflw.~s mama“. nnm.~¢ nam.am ~mmq. ;an. m:ra. mao.o: -¢.»H :m\m\ma

oaaasm a::o Hfiucu oadum smock eadysu «lava «c J: pa.m scum ae>aeg :mw9ma4 Mafia saga

:: um :« 030

623:“: :30 HHH .u: figrmh

I 5.. a M fi
..ma «onem.m czr.r>¢

tn

n~.m3 0mm.3n m.a.:m o:am.~ m.m: 3,...H\r
and mu “H3“... 5.. firmfloimw mawmo: $093. .333H\... .:9H

33... www.3m am~.wn 033m.: :.23 :m\cfl\n~
Wm.NH www.mn ahjoeu OLumé n.63 du\~a\mfl
mc.m3 m~»..m m ..m: mmmx.: 3.3: xxxr3\r3
H ..m om...“ ohm.33 m .m.m n.3m :uxcncfi

\ - \~ § 9 o ‘\-3
. . O .... . n. O . J... . O n. O n. T \H
a... 0 0k. $5.503“? “refill . L... w“ 4.x..- ”Pix? ....v C! Ln LI .MhLb.L W. H

 

00 3.33.3...“ 0.33.25 ngoh e: ED 5.0....“ 33.33 eudfl

I'r }

3.3...3.........:...3..E ,. 3:. 33...: .36 33.3.3.3 Eon 1.333.. 4. 3.5
3333933.... .3333 .3333 .3...33.....3n 0:33:33. «333.33.33.33 ”3.333.353 ...... "3.3.33. M3923...
3......qu 52.0 ms 3333333.... .3: 3: Huh 3. 3.3.3. «33.5 33353....0 .3333uu23 maf.§.m
33.30 :« :nsouuux

3...... u u .... gym. <..3....

89

._ .m $95.... 3... 3. m nifburxé.

fir.\3io4.fi
U: r

f

.
X

00: ......H «.mw

9... L

«...... ...”.

.‘l‘ .‘I. O.‘

‘

v.31”... . mu
o»3«.w
amm.~

cause 3:33a

a

“Miscauc

cfimhofi

wanm.c

$91.3...

.2:an

.... ho S.

.o >H

nzcmh

I“).

‘3
I

2

£1:

0

f \
I

www.0n
wmaxnfi

www.moc.”

OX? #SH fl... 9 0H

+u\.3\pa
:axwflx-a
:.\:H\ma
:n\wfl\ma
3U\n3\m3

¢a\oxm3

..1... \0\N

..(s 0..

04a

 

+1.).OH 00:... gm smauuv><

wam.m oner.p :xmxa. mcflfl.m ~fl¢g.:fl Neflc. age. 3.3” :n\:a\m~
»w m.» cm v.9 ancm. «Hm .c :mMH.w :0:3 «2:. o.mm :<\ma\pa

Q U

maHN. H N mm.w finch”. wumw.w ouzm.ea c:::: pqé. -w.;H x,\ra\m

;w<.- mm~m.m 3:2:a mace.” omww.m sczas ofe. .flm na\flfl\an

mHNH.cH H% a.“ cu:;a. mmaw.» onxa.:fl azsst axe. 3.3M n<\ua\ia

it . st I

x . _. a. .. . .. . . . .. . a _ ... .. .. x
(v.93: K+...HK.~. 5.33..“ . 03,531. Nrwc.eH ”LC. misfit. 0...." 7...\C\n.n
New. H.0H on...“ m . 4H.” ”.63.. wan....... . P .Cub. .... m1......f.. $30. m. 3H fi.w.\w..\.m..d

 

0093...“...m OMASO drank“. ”257.5 c:c¢h $3.323 43:81.8 pm..w.._..r “.34.... ”Adam Guam

“1.2;” €30 pm .9.» M343.

89

a

3.. cussim c3....fi§¢

max. 3. 4 a n. i... .... a) \ W3+.o__ 3.54
K ... ... I P I» I H ..x 7. .IN o. X. ... PI 0‘ r

«.H n ;.oy mrwx c.n= Ja\fla\ H
mam. H muaa.w :-:.M qufi.fl ww~.fls mpv. ~.H; :.\FH\ H
a « RH mm.fl.m mwp¢.n mm ¢. w«+.?u mac. 2.,u :»\:fl\ma

N): ...... «......iicnu wUmcmo

5‘ 1‘ ..\ .. . «A. a! :\ r. _ t

a w flu are. m.Hu :r\wfi\m
-ofl. a vmxc.w mach.» :Hma. up .0; five. w.3p ¢m\or\ma
« my a.» m~¢m.m o mH.H mm:.pa we. :.am :u\0\ma
m

m
.... ‘ . . ... . . .a. ... ....“ .0 d,
Omar.“ Ctrmoh mumwmzxac $1373. mug-C; wan... $2.0: +3.4}. Pd

ocifié cuppa Hausa 25: go? 333% .3936 firm 33a 34b

n;g

Rm .....4 “0 “h“. ...(f

vascfimco PH .0: Rama.

90

thméé 005%,..m a.“ 3.413“

A up.- mm» .a
3.... .3 a...~..._m.....

‘4
’4?
‘
“
‘4:
.

”H.m

«Hm... .3

t

\fi I

. \ x
w... . ..
\IO‘I 1.

mac...» . ...
33.1. » I A.

“\II. wl'. n?

.A. 4.4. o A...
4 P r C...

”....L* A....nufl

Cm» SE a me

"tt.’

3‘ 0."

Clad",

mac.

m.¢H

.H...\.b.g\3
..rxm H\mH
:.\oa\mfl
na\flfl\an
x-\ua\-a

 

O ( 9. .. . . x. \ t so .. .\ .

m .4, HA K...r..~.....~ .3.... .. C...w,. . ow. NNNC . 4..” mt?“ C. A .2... 0......H 3..\C\VH
mowm.ofl o.qn.v w.m¢. wflnm.n wvun.gn ww.e. ass. m.x~ fiw\w\ma
ous.~fim cupso Haven cram: ¢cc$m c .wcw Hmpwh ncwxv u_.: xmwn Guam

Humane a.“ O. o

2...: ,3 €50

5.“ iv...»

...»...dh

91

.113— u n.2- --...-~-. --','u wns‘r H ""f'ef."
a. ' ‘- J

‘ n- 35" 31.. a’l‘nh "PM'1"“' s§un “JE‘..§-

ngcrimentfil Sopravea Lppctita
Deprevcd a3. firetite nzy b0 yr 91 seed er poriacntnFIy by

feuding dairy CIIVCB on caneon‘rated atione in the form
of either vholo milg. or grain mix.ure contsining 2:316
pro min. ozwcr 3. nine: ale and v1t:m.1nes for norm 1 gro.th.

In.an attempt to cure thie type of deprgved appetite,
cantrauictary reculte have been obtained from feeding cod
liver oil. egrup of iron pho:ghnte and whee: bran. The cod
liver oil relieved tLo dcp;eved np>ct its in caqu& 6-14 and
Colo, bufi failed to relieve the cauditian in Crlvee C-15,
033, G-Lé, 0-35 and 0-26. nikuwise oxidized cod liVer 011
did nut cure the depraved npgetite in uni £18 C-L4 and C~25.
Syrup of iron phosyhnte relieved the depravoa rpyetite in
c 1: C-.z7 but h“. no beneficial effect ugon uni £18 6-16,
0-33 and 9-45. ‘ heat bran relf eved t e de;»rc?ed rp; ctito
1n cvlf 0-45. but it uni no effect chn fed to c: If C-LB.

.eso ree::u1t8 indiczzto that tic deprcved up)eti o in th

cases mcnzianed are nut caused by any one egcc;fic factor.

Hegntivn results have been.obta1ned in GVnry instance
there mincrrl eup>1emuute have been.given in order to cure

the depraved appetite, as the falloving table shows:

92

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

flinch-1.1 (31131.10-..th fed £211.33le natiL-er fiesulte
talcum grbonato fl 0-23 ‘ 1'10 age
”loculcimn 33120::ghnt3 0-15 T110 cure
w — ~— +— - w 1mm...
Sodium chloride C-IG, C-.‘;:3, C-LB 2:0 cure
Ground limogono rock C~.;3 " [:0 (31;:
Acid “p21;::~.hxto A C-f-JS no cure
gonna noel C-L'B, C-IZ : Ho cure
Bone flour 0-25 Ho cu;
iiagnoeium 13310:.3115. to 0-37, C-39 flo cure
Wood ushee C~32 :30 can
Alvfalwia [amoral mix‘ooro c-ié. C-17 :40 cure
Row rock phosphajto c-5 Mfume
Sodium carbon;;te C-6 “1:70 cure
Flowers of sulphur 0:228 150V our:

_-

The roflalte of tho metabolifm experiment cauouotcd on
or:ivoa C-18, C-L , C-25 and C-‘ 38 t;'hilo they "(to caiioring
from depraved appetite ehoue tho: tnoco anictlc Ltd 9 titivo
Ofilcium cnfl phoe;morons bulsncce. These results Seem to
indicate that a lock of minerals or the lock of tho minorol
retention factor is not the cause of depr avcd apatite
occurring on rations rcet'iotcd as to the a-..;‘; anfi Lizlit“
Of I0. «3" ‘11,}: g‘GQ

?hcrc depraved cpgctitc cnc irri tchility t rc both
prodzcod b. flooding a concentrate ration. tho ccfiiziou of
different mineral eupnlcmoutc mansionoc relieved the irrita-
b11123, an: L3 .3 no effect Upon the doprQTBd 99903130. This
inflicotce that irritability and dcprcvoc 59 :c tito are to
caper: v0 dieoecce, althoxph th25' mrzy both be roducod under
identical conflizizne.

Roggers (5) and Lgnch.(9) bcliovo t-ot a deficiency of
protein is the cause of do ::rcved c2963 its in some Clo: cc
of livestock. “atever, the food ing of tankcge to L-LL. bland
meal to b~lo c.d alfalfa.mwnl to CoLfi as protein cup,lcuonte
foiled to relieve the depraved appetite. This indicrtcd that
the depraved cpjetitc was not duo to agino acid doiicicucy.

The depraved cp9ctitc woe Ju.' t at marked flaking the
Winter non he as during the summer. indicrting that the ultra
Violet rny from sunshine has no bcnriicl:1 effect on this
diecaee. T“ie is further dcmozletrcted b" the 9103a? found
on pegs ( 125) of the cpgnndix. Knowing five auiurle chewing

tho fence while in the direct eunlight. Three w. Ls previous

941

to the t2. :36 this picture was #:2211811 t1: -3.-1:1. "3:18 hacl bean in
the 8111111; 5111; seven hours each my.

In all came algarc the c- agacri. 1311351 5311341511? were rc-
ocivins tic-1d guality roughage in the form of 3120.211: or
alfrlfa 1:23;: ficpraVed apjetite (1161 not dcvclcju «he cam as
t1; Lizzcthy 1917 ms: limitad to one pound -_!)£."=r (ls-y the dc-
pra'red apactite was wnii’ac 8 ma in calves 1,-1.8. C-19, 0-
am 13-1-3... "The depraved 1399015130 in calves (”-35, 0-77, G-*8
811:1 U-FD made 11:8 up 311:: 81:00 as 80m :8 BliE‘lff‘. bay was re-
rfzavad from the ratinn. 911111011311 tLe MIL-.1516 1:236 ’11 0:" the
rnghagc 12110;: wmld cat in the for: of corn £5.1ng and
mica: straw. In all probability the two caves 0-13 and
C-17 1.2; re depraved a 99e+1to use ('21 icvcd by adding wheat
straw to the rat ion. died of workmee and 9:311:01: ion bei‘ ore
the 8.99 avad arr-cute had time to reappear. Thcra 8:39:18 to
be a factor 111 food. quality ranghaga 1:221 ch prevents the
depraved aptmtiue. The failure of alfalfa térfl to roll: vs
the dcpravcd :29 :9 Lite 111 0271?.8 C-EZE’. cnd C-l? indicate that
this factor 18 flat soluble to any r‘p9mdable 0x2 .111: in
lute warm water. 1118 factor 18 9101351131.? not a mineral
since a miner-#1 mixture eirzilar to the minerai combination
£9212ch to relieve the depraved appetite. Emmi-11:35 the aggression
Of 132113: 63111191: he the factor, cocaueo the EIMVlng . Oct 118118
and wheat straw eupgalicd plenty of bulk to stimulate proper
11113210103102]. functioning or: the (1132985179 track. Teas re-
Salts ngrce with those of ZIcCamil 8h (49) Hm fcimd that
the 19.51115 of alfalfa 11:-1y prevented depraved agspctite 1n

experirmntal 9111:2318.

A study of the blow; gnicmree of 0111193 13-13. 11:-1L3,
0-23, C-35 ana 6-35 that were suffering £33m de;11ra?od up etitc.
EAOWCG no rnlntiinzgip betwocn EEG blow origium. 1:3 1‘3 3 E,
chlorine , 3 rLon dio :ide, proteia uiflrogen, non-prnzain
n tragen anfi hcaaglobin and the depraved rpjctite.

Li Lu 120 a etuc3 of tic red Llooé cnfi 'hite :ljod
corpusclo c ant of calves L-IG. 9-33, C-35 aha G-ES unggnrtcd
no relatinz‘zship batsm- n ‘31 e 1103:- (ac-111331121: r313 1122121321

cpJGtitc.

Eepravod A:potite in tho Eicld

 

The 01‘11‘1311 of cod liver 01]. to the ration of field
afilvee l. 3, Y, 9nd 4 cured the depraved npgctita. Qiie
indicates that a lack of 0 facts: carried in cod liver oil
mry be the cause of the depraved cp3ctite that occurs unis:
orfliunry farm C3naitinns, 130:0 tha rniwrle are receiving a
poor finality of key.

-he investigatiansl mark canductcd 11. th d<1rs.cfl
t??CtitG as t occurs under farm conditicn: in the thzmb
region, rointe to & phosphsroue deficiency {8 being the craze
of t? 0 day: avod ap1ct1te. Cows in milk, snfi young grcwing
animals £933 to be the aura susce title, rhile older non—
1act3fiing 312118 trn not cffcc cted to ca mtrxed a degree.
”heae res alts 81:00 nit the work of Sheila: (L1) 510 con-
clude Eat the depraved 33133ct1 o in outh “frica ie -cnsed
by a phosphorous deficiency.

:mrlyeie of the posture 8111.: plea from farm :1. 3., D.

'9‘“

3 and F, where depraved‘appetite occurred. gnawed only one-

11:11:! the 1:301:12. 31‘ hmphorozza iozmd in :h 3228sz if 1131::
froza the 15.. f. C. farm and from firms F and -, where depraved
appetite 1:123 113s i-mnd. salt-‘0 the analysis of 89.119102: of
sweet clover pasture collccmd from farm ... thou-'8 that the
succulent ate-.56 contains only 0.0533?» par cent yfimagahomue.
while the (feed stage captains 0.0335 ”931‘ 00:11; phorphoruue.
Tho succulent 831236 18 revuzeeentative of the pasture union
depraved Ejpetite Gavel-agmd, t 12110 the med stage 19
representative of the _-:5-2t:xro Mun Lino dc3‘:1‘m'cd {7;} etite
(Maegwered. 231218 may 82:91.111 1.15;! the depraved ag‘ctize
occurs mare often in the spring, while the grace is 30:31::
and tender, and then diOEEfEOEIG when pho::;::h:r0u{3 5.8 being
tored during; the Llo-m xxx-.1 8.0061 61.521309. The nfijitdnn of
grain to the mtitn chm: 12:0 middle of tie:- smzmcr_,.;;_§3'31.:o
account for the diecpjz-csrnnce of depraved epgetite at that

time, since these amine are i: irly 2115;}: 1;: f)3108;)h03'0’.i‘;*.

97

t,-1'I:.Y"" '7 .If.‘
..3-¢.-.-...J..r .. (3“.

1 Dcproved eggetito any be prodocod by feeding crlrue

,. a.

on a concentrate ration Containing adoiuato Quart“, protein,
minerals on; vitam'nce for no? t1 growth.

2 Boprovcd epgcti e mry also be proaucud in dtiry
czlvoe receiving an odo'uote ration by substituting wheat
straw and corn allrgo for flrxlfa hay. the inflicatos that
a factor in good _ualit3 hay pretente acoravud epyctitc.

3 She results indicate that depraved appetite no it
oc'urs on rationa limited 28 to the u=ntity and ,uxlity of
roughwgc, 1c neither due to a nincrcl deficiency, prrticulxr-

1y carilum anfi phoxpharoua. nor to a lack.of the aincrul re-

tention factor.

4 The ultra violet ray of the ranchino has no 3f§ect

on d praved appetite.

:56-

5 "tore 18 no rcletiwnfihip between the otlciun,

phorphorout c lwrint, onrbon dioxide. protein nitrogen, non-

pratein nitrogen cna hemoglobin content of th blood rnd

dcyrcvcd npjotitoo

6 There 18 no relationship between the leuLchtic

count of the erythrocytic co.nt of the blood.rna depraved
appetite.

‘ u'n-r \Q .
7 Dopravcd appetite Cfldflfi carry cattls in coxtorn

eoctixns an; no flue to c pho:phorou8 a0£ECiOhCEO

(‘3

(A

98

fi11*“H--~~,-~
.2 11.0.», L. J.

.D. 1.- - $.r n ~~-
lo-lxnd. t. e. newugn

2L0 ”merlcen.llluetretcd Kcilc:l -ictl er J 1393 ~C13153
.eleI-1,1.orcrd
Bane Chewing by Cettlo

Univer ty of: Sent: 12:, Zzzpuriit- et ‘37th Cil‘ultlf. r 1.;3

“out a L;d 20 Ear

=tzla. 3:508 138 to 163

‘ 3
U. L. D. L. 1 15, pages ;8

'3 3'; C H 9.
“oiat'r“. ‘. a.

Country Gentlemen 81:533. march 18. 1916
Butler. Teit

De 3:2"(d 'pwetlte

37rogree: iver Farmer, Valium {‘15. ergo-15:71. bept. 18. 13.0

ncIntoeh

Disease 0 flames and Get la, page .34

Law

Farmers Veterinary leer. page 344

Lynch, C . 34‘.

p,, r r;
Diner as of Seine, Rages 049 to a O

10

13

14

15

16

17

18

19

99

g Sense in Captive Lild Kan L12 one Birds
Lancet. The

Potholoyic l Clutter . Vol. 1. 1936. page 216
Lencet, The

Bonlleinia or Buliny. Vol. 8. 1899, page 730

Tomcat, She

O
f:
A
:n
m
f’.
A]
H
:3
C
"'1
m
G
‘4
o
*1
O
...;
O
I“:
0
H
U
C)
q
o
"J
7‘3
‘6
...:
OJ
\3
...:

A

‘Uebcr die Coechmocxee;plindung garludcr under

rechiticeher ainder, £7, 76. 1394

“ice. Journrl Anaricen.:odiCK1 ersoeieuien
?01. 46, 1006. pnge 330

Davenport. 3.

Growing Cattle nithout Corrce Feed

Illinois agricultural axperiuent itation

'7'?

Bulletin $6. 30308 363 to t;

' n

{3121133011}. J. n.

Fe-ding R flier es en Grain alone

Utah agricultural Exocriment Ltetien.3ulletin 51
Jones. George 3.

PerVereo Digestion in‘Yoeng Ruminxnts
American.Vot. fled. Auroc. Journnl

V01. 53. 1918, page 538

“O
14

to
to

27

30

100

HUCfinflliEh. L. C.

Kilt as the Cole biet of’fiumlnxnts

Iowa agricultural xx orinent itetien

Research Bulletin Ho. 48

Voters. H. G.

Capacity of animals to Grow under Adverco Conditions
Reprint from Jroeeedinga of ioeicty for the Tromotion
or agricultural bcience. page 33
rorbee and Keith

Ohio “Hp. Etetion Tech. Bulletin 5

l

flouredden, f. H.. rod Felec. K.

F

Chen. Abstract 6. 1051

111811 . II.

Journal of Camper. Path. & Cher. :0 H0. I pngce £3.48
Huston, H. H.. & Brynn. H. B.

Indivno btetion Report. 1879. pages 73 to 74

Pfirllcr. J. 11.

pr. Etetion Eccord Vol. 16. pages 144

Lnurrel. J.

Exp. fixation Secord 17, page 193

Kcllner

Drndhr 1cm er Butatiero. 1907, pnfc 1&5

Cited by Henry & garrison, Feeds & Fec=ing. page 64

Lcwitc. Mo
f‘ati n fieeord Vol. 19. page 884

J

4.3! '10

fiellomlert. f3.. $011,: the. fin... 3300:1905”. Xe.

-v 'i I"
Chem. Abetrrct 6, ptbo ”do

Sxoeriment Ltetim Record Vol. 18. page 178

i.

53

393

q
C/

"l
I/

40

‘41

101

31011811}!
finn. fled. Vet. 56, 1907. no. 4. pages 193 to 300
Hutchoon. D.
Aer. Journ. Capo Goad Rape
701. 24. no. 4, pngoe 479 to 48?
fl
Kogon. G.
339. btation decord. Y)l. 11. pages 936
R016. H. 5. and Astor. B. D.
How ZOfilnnd qurnal of Dept. of arricllturo
Eovomber 15, 1910
9.83011. B. C 0
Journal of Dept. of Agriculture. 30% chl:nd
Bovenbor 15, 1911
Renkes, C. J. and Aston, B. C.
Jourxal of.Agricultare, new Zealrnd
Department of Agriculture. Feb. L0, 1914
Car 3, C. u.
Am. Vet. Red. $820. Journal 53. Series 9.
1919-30, page 007 I
Horth Cnrolinn 53:1. L393. fitation Regort. 1911-13
Report of Vet. Elviciou. June SO, 1912, 9550 L7
thilcr, fir Arnold
Journfil bept. Agril. South nfrica
march, 1931, pages 19¢ to 135
th hfIiCE 5th & 6th reports

2'01 0 :1: .

Depertwcnt of sgricu:ture Sou

an

April. 1918. :38808 L5? to dab

47

48

49

51

103

Conan-mot

Journal ot’tonp. finth. & Therapertice
V01. 38. 1915, pages :53

Thoilcr

Journal Cong. Path. & Theroyortice

Vol. 23, 1915, page 33

' Robertson. “111153

Journal C329. “nth. & Thorofiartice

731. 23, 1910, once 32‘

Stellar

Second neport Director of Vet. Keeuarch

Dept. of 4. Wiczll'mrzil Uni-.111 of South 2’.fr..cn, 1’31...

Vlljoun, ?o E.

7th & 8th regatta Director of Vet. Acccarch

Dept. of “grlculture, Union of S nth 3frica.

pages 458 to 575

Theilor, nrnold

Journil ucpt. of &gricu1tare Union fiagth airica
June. 1940

Funk, Cseimor

fhe Vitaminee. Eoconfl Edition, page 153

HcCandlich. nnfircw C.

Journal of uLiry Ccicnce. V01. VI. 50. 4. July, 1933
Green. Sheila: & Viljoun

3rd & 4th Annual ficpvrte of V03. Jcccarch

‘h nfricn, 1915

Dept. of'ugriuulturo. Union of $01..

thiler, Green and buioit

Journal ucpg. of unricalture. union of :o;th Lfricu, 13-4

‘)‘I

Currey

3133052808 Of battle. U. :1. 38 A.. 13.33. {Eff-:50 .38
11011891}. and Dollar

Discusses of battle, page 159

Road um“: ii.1ff..:£;n

Un:rzl.lisi;ml ditto frozxi viz-or}: conducted Liuigfagjzsn .uxg.

3331:1031, (net 23:3. ring, z.'-.€.ohingn.

AT? ‘

“*.‘T“.'
ch14”“'.

1013-3

104

H g". °~ \-. .4: , ~' ' --"
.ublo 21.11153 neg...) .. :1 c1. 0.123.?08 used on the ex» rigont.
Age in (1.748 Ethel]

‘31 r. .1 H ,_ __
Cf'lf HO ( 7-... “...-..flusid on ,-.:0VulO}')€;d 39-. UG'C'OIQpQfl
.1 . ..c.{ .25}; 21:23:11; preveu apgeatite irritanlity

C-lIS
C-ld:

Hula

33:; 13

2.11: 10
30:12:18
”(3:12 10
1‘ {3:31.18
TI’c-n-ile
1" 2:16
Fonnlo
Female
393210
Female
21:- 10
licle
21' 10
390211118

F (3:11;:- 19

‘ -.'
z .17 10

Female
Fez'mlo

Fem 16

7

{>3

{‘3

NHOH

19

1'. ‘1
c}

F‘ l6 hi ‘9 Fl (3

1&3
IE one

138

C3
.4

Bone

60
130
Hone
159
70
137
163

Home
171
1138
Eons
Home
180
2370
400
860
None
210116
130
210110
2:18

2:: one

..1
(3)
C)

I: one
1?-

I.’ one
I: one

Hone

‘ ...

II\

0 \
0.».Hfl Q'Hmo QHJPWWH @302M2m HcmenrdHCHw OH. H»w_.w__uoawsdmrwm pdwfiw meoV.fi~.HH.OQV~dmwm GO ammrfip<ag unfimfipfiwo

 

 

mo.ooo mwumsd noonfidoa 96.....mapdo . ”wagon 0.2;...qu Govoawdo

5

no

1

roonooawwa

Ho.ooo

mm.ooo.oco

...n o;:w3 a.womz:.d.u

.u «wwwocaoo
mbOJJObOOO M. m. y .

 

'5'” -_ . .- _,.

 

 

oywn 01mm“ \QWQmw mwoxpdm Howanpo: 0m Hoswoo<dmm wan wwwavnoowamu a0 awaufiqma vaoapaw. 7

mo.000 mwpmwa nonuaqoa pvvmduao gnawoa aovam<oa wwmmdpao

106

Ho.ooo rwvwoownmo

mmoooouooo

NH ouupu awwwwnuron

ll\\\\\\\\\$lllllllltj

\

Vm. 00.000

 

 

aéw

wo.ooo Gown 91mm. anon: mrosuzm Hmwfinuo: ow wozroomnom fiza onwavuoownwfl a0 mmvumqma wbvmnwem.

 

 

 

3
.

no novquoa , zwuwoa nmvnaqma fibrowwfio fi 20 nobumqoa vvvoewdo
7o www.mdwflo m
o , u
1 ..
.
Ho.
_ mm.ooo.ooo

.73. osfio nip... .32-...an

m. 00.000

 

 

. i ? ‘r—‘r—i fi flit": I“

 

 

o-..

 

 

mo.ooo OVHH Olvm. nnflrfi mwoawbfi wamdpor cm Hmcxoowawm can onwawncowdmm do nwhH¢<ou fiwvwdwam.
1
no .
AU
1 .
zo novnpén . H3289 92.25me £30034...
mhnmdpuo .
. y”,
Ho.ooo - willlllllr. waxwoownma
M
_
M
mm.ooo.ooo H

hwfi QCUMO wawwfindwfl

“
H
1
w
_

\r/L/|\\\ mgfiwncgfw
_

m.ooo.ooo _

 

\
\ w

.
r o n

ow: 0:5. 09.93.. magfium Hmwmdpobmvpv 63335....3. 5000 €0.33 .50 3.0320... mvwmgdm.
2. n - .. - . . .

9 32.3.4 a 20 92.339 @3533
.m 13.31. ,,
3b ”9..

   

..uj-fiur “Ar". |_MA1|

DEPARTM INT

.
...—“w—J

 

 

 

 

 

 

 

 

} 4
O
by V r } ? D
a _
I t v
I
.
c o o b.
L, F ' V c
D . . . O. ...
h . I ‘0‘...
.1
. . .
—
I O
, o
n.
. _ _~ h o 0
H D r ” 1F *. (b ”4 F ? P b.
J. , .
. I 4 ,_. aw. . — ...
H H a p c ...-not foloo
. o
. .
~
. ¢ . o . .
I u —
V . _
. . Vx {I v . + - 1
o A
. I ..
. 1 .
. a o . .
« C.
o. .
. . . . . _
k p b r ? > r [I
0 hr . «3 ‘41 1|—
— . _ d .. .A
. n _ n u o o oo .
— .. _
. _
u . . .
- . n A
— . g v .
n o o p — .
. n A
_ . . ._
. _ - . ,. q . v. ,, l o.
I o . - olo . .I Vol... - An'OIIAI- 6| 10-9 0 a L. a . . I . .v . u v. . a I o .19 n a
— . . .
n o n c 9 b — 9 6.
I a c .
n , c . .c o
_ . . . _ . .x a . . . ... .V v
I. o o _ . . . 1. . . . - ... . .. < - ......
. _ . _ . . _ ‘ .
... _ n . _. o . . , ... . < . . . . .. , I
— . . . . 4 .r. . u , W — 1 u . . -. . . ... . V . n c . u
. p? I . z... 2.... o. a I ‘0. . ... o . . ... o . u . t _ I u. . n“
.0. hullrn'itoorlll ..I-‘b|.r'lovb .I II l’vllinl I . I llDIIII on . n h I n [DIDI I‘DI-I'. I L I L In'l' 0| DIIIDII. l'lllh'llrrlllvlbllllnl'. 'Il. - I I'm .IIII’Illllr' .II ltl'I-I'lrt‘ ||||| .l t-
‘i| I | ' \I
I' In,

 

95H O'Hm. Quin» 47......33m. no 71;... 231:. 3333.23; :5 3.32” fiuafififla .50 flownflfiwa finnodwno.
... .....w A ., ._... .... .. , .II. A.

>

p
A
r

.......

OP "ATHENA

...... . .o.+s.

......

 

EGE

o
e
S

.....

0
.AN mui‘buum c051.

o

 

a

13.3 ‘0
1:
km

I I I
. .
' ‘-“9~—‘-O*-o -‘—
.

o

.-..H. ._ . . ,_., n. . _ 4 . ....
If. I’ll ’ o -h IhtEE—IJIDL . u I I?’t:'-EIF.III’-.W "I‘m“. IL|IL airfrt II'. q. I. n , .I o IIDL. I D lII.Ir w .lth I I I I! P. I I I . In D u n I IL ~

 

| \ | [L‘I 1;} IN! [.1 . Dl't“, .

 

 

......

a? uamminc

DIPARTM

......

‘

‘ I...‘

O
5'

m"

9

3 3
0 A
IAN an

2
‘

3
39.3.

1

6
A

....

 

II I Il"' I 0 II.

. I I I I o
I 1|. It I .| II'. D I '0 III I u I I D I I I I I III-r III I On. I I. log
0‘5. h

7. g m 01mm...
. mac a‘wmuzna;

”M W unmanaac
F‘s” ,

 

 

. Evian nafigaa
Eunaaga

    

‘ 615.5 an? mam n4wafiwéwxu ‘gnié it. 992.". m

.5: gnxan nwfinmw4¢n
....rm...w..¢d » “a

 

Martha E5 aw.m_mpavu f». . ._ Guam.

_ ma aafiflfie

     

a waaoauat

 

  

3

"L;;__

AM 0

‘4b--— . .-

r-ZARTMEN‘TJ or Mum:

. ‘,..

1 -‘_l

 

 

 

 

[1‘

z nfiH.fi O'H‘wo N...
20 amfiup<nn finia

up

an
.1

3‘ \a.\
assaLWI I

g

I

Hz, 5.-.. .. ; 3. ....23;

v' I. ‘

k . '3.
a¥8w¢a aanwwqmn awwawpwa

.2 f 4

 

a. 28

5;&mr\

 

 

 

 

 

 

 

 

 

(i)

MATHEMx ;-

. - »
.r_-I—-- .-

‘ A

p mud n-

"..‘ 517M LN 1‘

-.~1L--

7 L A T 3 1

Pictures of hair

from the rumons

 

 

bells collected

of oulveo.

114

115

o-+g4

 

 

nature shoring cross motion of hair

ball! collected from the muons of

on 1708 .

Picture of largo hair hall collected

from the men of a calf and a
wool ball collected from tho

man or a lamb.

 

U48?

116

Picture of col! C-lfi outing manure.

117

 

 

 

 

 

11:3

PLATE 5

 

 

:Plctnro of C81! C-MZ eating 2.:~.1r.

 

‘T‘ 49" R‘ra.% .

x. A

 

119

 

Bicturo of a cult that has a patchy coat of

hair. This condition in tho result o!

the ravenous eppotito far hair exhibited

by 0r. If 0-22.

 

 

 

 

Picture of hair hallo regurgltutod
by 0&1: C-BB during the nonth of

nay.

 

Picture of Cal: 0-25 lolling he:

tong“. Thir condition ottm

ccoonapenicd depraved appotito.

12.1

 

 

 

Picture of Col! C—Sfi chewing o board fence.

:1

2

 

 

 

 

 

Pictures of boards collected from

postures whore depraved appetite

prevailed, chewing ohewofi arena.

133

 

 

 

 

 

A ‘_

“9'0

333 t: 11

6‘1 “

 

 

 

8121043 of wood colh ctod from pasture
Mh.rc depraved appetite preVuiled.

shoeing cnevcd endl.

1234

-6,-

[rs-“re

.._- ‘V‘fi

125

{:4
I;
R;

 

Picture £21.32:ng five calves chewing; a board

fence. Those calvea had received seven
hfiure of 81118311118 daily Iran ..Qpril 1

to $91.11 23".

l Will!HIHill!ll!IllHill!HUIHIIHIHIHIWJHI

31293023561743