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(21 - 40 of 28,443)
Pages
- Title
- Zwitterionic excited states of the delta-manifold of quadruply bonded metal dimers
- Creator
- Engebretson, Daniel Scott
- Date
- 1998
- Collection
- Electronic Theses & Dissertations
- Title
- Zinc-phosphorus interactions in Phaseolus vulgaris
- Creator
- Lessman, Gary Max
- Date
- 1967
- Collection
- Electronic Theses & Dissertations
- Title
- Zinc levels in soils as related to zinc uptake and yield of Phaseolus vulgaris
- Creator
- Melton, James Ray
- Date
- 1968
- Collection
- Electronic Theses & Dissertations
- Title
- Zinc availability from soil applied zinc sulfate and zinc EDTA
- Creator
- Judy, W. H. (William H.,)
- Date
- 1967
- Collection
- Electronic Theses & Dissertations
- Title
- Zeeman background correction with an electrothermal graphite braid atomizer
- Creator
- Gano, James T.
- Date
- 1981
- Collection
- Electronic Theses & Dissertations
- Title
- Zebra mussels (Dreissena polymorpha) in a Great Lakes coastal marsh : population dynamics and effects on the invertebrates
- Creator
- Brady, Valerie J.
- Date
- 1996
- Collection
- Electronic Theses & Dissertations
- Title
- Zapotec use of e-commerce : the portrait of Teotitlán Del Valle, Mexico
- Creator
- Rivers, Deanna Sue
- Date
- 2005
- Collection
- Electronic Theses & Dissertations
- Title
- ZZ 2p-actions on the 2-dimensional and the solid Klein bottles
- Creator
- Abudiak, Fawaz Mohammad
- Date
- 1984
- Collection
- Electronic Theses & Dissertations
- Title
- ZIKA VIRUS-INDUCED PREGNANCY LOSS : LESSONS FROM THE MOUSE EMBRYO
- Creator
- Watts, Jennifer Leticia
- Date
- 2021
- Collection
- Electronic Theses & Dissertations
- Description
-
Adults contracting Zika virus (ZIKV) exhibit mild cold-like symptoms, whereas newborn babiesexhibit fetal defects ranging from mild growth retardation to miscarriage. Aside from transmission via mosquito, ZIKV is also sexually transmitted, which introduces the possibility that ZIKV infection could occur shortly after conception. However, the mechanisms underlying ZIKV-induced birth defects in early development are not understood. I hypothesize that sexually transmitted ZIKA virus infects...
Show moreAdults contracting Zika virus (ZIKV) exhibit mild cold-like symptoms, whereas newborn babiesexhibit fetal defects ranging from mild growth retardation to miscarriage. Aside from transmission via mosquito, ZIKV is also sexually transmitted, which introduces the possibility that ZIKV infection could occur shortly after conception. However, the mechanisms underlying ZIKV-induced birth defects in early development are not understood. I hypothesize that sexually transmitted ZIKA virus infects embryos around the time of conception, leading to the most severe congenital defects. Consistent with this hypothesis, I have discovered that candidate proviral factors are present in mouse embryo-derived stem cell lines and preimplantation development. However, embryo-derived stem cell lines exhibited low viral infection and replication. Nevertheless, Puerto Rican (ZIKVPR) and the Ugandan (ZIKVUG) strains of ZIKV caused two-cell embryos to undergo developmental arrest. Moreover, infected blastocyst exhibited reduced SOX2 expression, an epiblast cell marker, CDX2 a trophectoderm cell marker, and SOX17, a primitive endoderm marker. Therefore, my results suggest that preimplantation ZIKV infection causes embryonic demise or embryonic cell fate defects depending on the time of infection. My studies are significant to human health because they will further our knowledge of viral infection in early pregnancy and the outcomes.
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- Title
- Z-source inverter design, analysis, and its application in fuel cell vehicles
- Creator
- Shen, Miaosen
- Date
- 2006
- Collection
- Electronic Theses & Dissertations
- Title
- Z-source inverter based powerconditioning systems for PV power generation
- Creator
- Huang, Yi
- Date
- 2009
- Collection
- Electronic Theses & Dissertations
- Title
- Ytterbium based alloys for space-based thermoelectric cooling applications
- Creator
- Lehr, Gloria Jeannine
- Date
- 2014
- Collection
- Electronic Theses & Dissertations
- Description
-
Solid-state thermoelectric devices are of great interest for researchers in many fields due to their potential to increase the efficiency of electrical power generation as well as provide localized heating or cooling in inconvenient environments. Improving the thermoelectric properties of the materials used in these devices is critical to improve their efficiencies and thus feasibility for niche applications. Unfortunately, several of the underlying materials properties are inversely...
Show moreSolid-state thermoelectric devices are of great interest for researchers in many fields due to their potential to increase the efficiency of electrical power generation as well as provide localized heating or cooling in inconvenient environments. Improving the thermoelectric properties of the materials used in these devices is critical to improve their efficiencies and thus feasibility for niche applications. Unfortunately, several of the underlying materials properties are inversely correlated making the thermoelectric figure of merit difficult to improve. In addition, the performance of traditional semiconducting materials is degraded as the operating temperature is decreased. Thus, a unique approach must be taken to achieve larger thermoelectric figures of merit at low temperatures. The research presented here investigates the use of intermediate valence Yb-based compounds for Peltier cooling in the cryogenic regime. These Yb-based intermediate valence compounds demonstrate large Seebeck coefficients at low temperatures, which is essential to a large figure of merit. The Seebeck coefficient is related to the fluctuating Yb valence, a relationship that is investigated in several compounds and utilized to maximize the thermoelectric figure of merit. Solid solutions are synthesized in order to reduce the lattice thermal conductivity as well as alter the size of the unit cell. Changes in the unit cell volume may contribute to a change in the average Yb valence, and thus be utilized to tune the magnitude and peak temperature of the Seebeck coefficient. By reducing the lattice thermal conductivity and optimizing the Seebeck coefficient, enhancements in the thermoelectric figure of merit can be achieved.
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- Title
- Youth work and psychological well-being
- Creator
- Safron, Deborah J.
- Date
- 1999
- Collection
- Electronic Theses & Dissertations
- Title
- Youth sport coaches' education : the parent perspective
- Creator
- Litherland, Martha Sue
- Date
- 1995
- Collection
- Electronic Theses & Dissertations
- Title
- Youth recruitment into fishing : the influence of familial, social and environmental factors and implications for education intervention strategies to develop aquatic stewardship
- Creator
- Dann, Shari Lea
- Date
- 1993
- Collection
- Electronic Theses & Dissertations
- Title
- Youth Appraisals of Marital Conflict and Genetic Risk for Attention-Deficit Hyperactivity Disorder : examination of Gene x Environment Interactions Using Behavioral and Molecular Genetic Methodologies
- Creator
- Nikolas, Molly A.
- Date
- 2011
- Collection
- Electronic Theses & Dissertations
- Description
-
Identifying the specific etiological factors that contribute to the development of attention-deficit hyperactivity disorder (ADHD) holds great promise for future innovations regarding the conceptualization of the disorder as well as prevention and treatment measures. A wealth of evidence has demonstrated that genetic factors make large contributions to ADHD, yet numerous environmental risk factors have also been identified. Uncovering the nature of the exchange processes that are involved in...
Show moreIdentifying the specific etiological factors that contribute to the development of attention-deficit hyperactivity disorder (ADHD) holds great promise for future innovations regarding the conceptualization of the disorder as well as prevention and treatment measures. A wealth of evidence has demonstrated that genetic factors make large contributions to ADHD, yet numerous environmental risk factors have also been identified. Uncovering the nature of the exchange processes that are involved in the development of ADHD via investigation of gene x environment interactions (GxE) represents an important step forward in research involving the causal mechanisms of the disorder. Risk factors related to the family environment may be particularly important for the development of behavioral and emotional regulation capabilities. In particular, conflict in the home has emerged as an important correlate of both symptom severity and impairment for child problems and represents a potential putative environmental risk factor for ADHD. The current research examined the potential etiological role of children's cognitive appraisals self-blame in relation to their parents' marital conflict in ADHD via tests of GxE effects using two complementary methodologies: behavioral and molecular genetics. However, prior to these tests, the phenotypic relationships among children's appraisals of marital conflict and externalizing behaviors were examined. In Study 1, the unique relationships between appraisals of self-blame and ADHD symptoms was replicated, indicating that self-blame was related to ADHD symptoms even when oppositional and conduct are controlled. In Study 2, behavioral genetic methods for testing GxE effects were conducted in a twin sample of 248 twin pairs. Self-blame emerged as a significant moderator of latent genetic and environmental influences on parent rated ADHD symptoms on the Child Behavior Checklist DSM-IV ADHD Scale, such that genetic influences decreased but non-shared environmental influences increased with higher reports of self-blame. In Study 3, tests of GxE effects involving a specific genetic marker, the promoter polymorphism of the serotonin transporter gene (5HTTLPR) were conducted in a completely independent sample of n=304 youth, of whom n=151 had ADHD. That analysis revealed significant interactions, such that increases in teacher-rated DSM-IV ADHD symptoms corresponded with increases in self-blame, but only for individuals with the low and high serotonin-activity genotypes. Findings from both studies are complementary and suggest that self-blame may indeed have a specific role in the etiology of ADHD via moderating of genetic effects. Results suggest that different exchange processes (i.e., genetic main effects, environmental main effects, GxE interaction effects) may be differentially important for the etiology of ADHD and provide support for an etiological role of self-blame in ADHD. More broadly, these findings offer an innovative approach for understanding the interactional processes between genetic and environmental risk factors and their contributions to ADHD.
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- Title
- Your obedient servant : government clerks, officeseeking, and the politics of patronage in antebellum Washington City
- Creator
- Bowen, Heath J.
- Date
- 2011
- Collection
- Electronic Theses & Dissertations
- Description
-
This dissertation examines the social, political, and gendered components of public office and government employment during the antebellum era. Historians have invoked Andrew Jackson's system of spoils to demonstrate the rise of political democratization and the emergence of a federal bureaucracy. But few studies have attempted to examine at any length the public servants and citizens who were implicated into political parties and connected to government institutions through patronage. My...
Show moreThis dissertation examines the social, political, and gendered components of public office and government employment during the antebellum era. Historians have invoked Andrew Jackson's system of spoils to demonstrate the rise of political democratization and the emergence of a federal bureaucracy. But few studies have attempted to examine at any length the public servants and citizens who were implicated into political parties and connected to government institutions through patronage. My research on public servants shows that officeseeking was a highly complex and contested phenomenon that was intimately connected to nineteenth-century political and moral economy. Its connection to the rise of partisan politics and its lure of men from more independent and manly professions worked to create a popular perception of government employment as a social evil. What is more, public office was regularly sought through elite Washington political networks accessible only to applicants with a relative close proximity to political power. My dissertation argues that these developments created a common ambivalence toward public life and a cultural hurdle to the development of a professional ideal within the federal government. How government clerks understood this dynamic and how they made sense of their place within the unique political and social environment of the nation's capital, is of central importance to this study. Officeseeking emerged as a gendered middle-class experience, and clerking in the federal government offered an alternative livelihood to the diverse antebellum labor market. Many government officeseekers experienced decreased opportunities for independent employment and hoped to protect their family's financial future with a clerk's salary. In their efforts to claim a respectable professionality, Washington clerks articulated an understanding of the relationship between the federal government and its employees that challenged popular patronage rationality, setting the tone for future debates regarding civil service reform in the years following the Civil War.
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- Title
- Young women's phenomenological sense of father and parental marital relationship and their relation to paternal loss
- Creator
- Darlington, Susan J.
- Date
- 1979
- Collection
- Electronic Theses & Dissertations
- Title
- Young male offspring of alcoholic fathers : early developmental and cognitive differences from the MSU vulnerability study
- Creator
- Noll, Robert B.
- Date
- 1983
- Collection
- Electronic Theses & Dissertations
- Title
- Young empowered sisters : promoting psychological and behavioral well being among African American young women through a culturally relevant school-based intervention
- Creator
- Thomas, Oseela Nadine
- Date
- 2004
- Collection
- Electronic Theses & Dissertations