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Title: Wittgenstein's Kierkegaardian heritage
Creator: Ort, Larry Victor
Date: 1997
Collection: Electronic Theses & Dissertations

Title: Wittgenstein's new kind of foundationalism
Creator: Brice, Robert G.
Date: 2004
Collection: Electronic Theses & Dissertations

Title: Wives of foreign students : their problems in home management
Creator: Lieberman, Leslie
Date: 1965
Collection: Electronic Theses & Dissertations

Title: Wolbachia induces resistance to dengue virus in mosquito Aedes aegypti
Creator: Lu, Peng (Of Michigan State University)
Date: 2014
Collection: Electronic Theses & Dissertations
Description: Transmitted by the bite of mosquitoes, dengue virus (DENV) is the most important arboviral pathogen in humans. Currently no drug therapy or vaccine is available for dengue fever, leaving vector control as the major way to protect human populations. The endosymbiotic bacterium Wolbachia has been proposed as a potential agent for vector control, because it can not only spread within mosquito populations via manipulation of mosquito reproduction but also inhibit transmission of DENV in...
Show moreTransmitted by the bite of mosquitoes, dengue virus (DENV) is the most important arboviral pathogen in humans. Currently no drug therapy or vaccine is available for dengue fever, leaving vector control as the major way to protect human populations. The endosymbiotic bacterium Wolbachia has been proposed as a potential agent for vector control, because it can not only spread within mosquito populations via manipulation of mosquito reproduction but also inhibit transmission of DENV in mosquitoes. In order to develop Wolbachia-based control strategies to prevent DENV infection, we have to better understand the interactions between DENV and Wolbachia in mosquitoes. Aedes albopictus naturally carries Wolbachia infection, however, Wolbachia-mediated viral resistance was not observed in Ae. albopictus. In this study, we demonstrated that the native Wolbachia induce a resistance to DENV in Wolbachia density-dependent manner in Ae. albopictus. A decrease in Wolbachia density within the host cells results in increased dengue infection. We provide evidence that a very low Wolbachia density in mosquito tissues where DENV resides and travels could contribute to the absence of Wolbachia-mediated resistance to DENV in Ae. albopictus. We also investigated the impact of Wolbachia infection on DENV life cycle. We report here that Wolbachia is able to inhibit the intracellular accumulation of DENV in Aedes. aegypti mosquito cells. We showed that Wolbachia infection inhibits DENV binding to mosquito Aag2 cells. We then compared the DENV negative strand RNA levels in Wolbachia infected and uninfected mosquito cells. Wolbachia infection also inhibits DENV replication in mosquito Aag2 cells.To further investigate Wolbachia-DENV interactions in mosquito, we carried out microarray and real-time PCR analyses to define host cell transcriptional responses that are induced by Wolbachia infection. Our data indicates that sixteen previously identified DENV host factors were up-regulated in mosquito cells infected with Wolbachia. An RNA interference (RNAi) screen revealed eleven host factors that are associated with Wolbachia-mediated viral resistance. Our data provides several potential targets for interrupting dengue virus infection in mosquitoes.
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Title: Wolbachia-mediated population replacement in dengue mosquito vectors
Creator: Ryan, Shawna
Date: 2013
Collection: Electronic Theses & Dissertations
Description: There are many vector-borne diseases, including dengue, that lack vaccines or effective treatment options, resulting in vector control being the primary disease control strategy. Wolbachia, an intracellular bacterium that can spread itself through a population via cytoplasmic incompatibility (CI), has been shown to inhibit the transmission of a number of the deadly human pathogens, like dengue and Plasmodium, in mosquitoes. In order to utilize Show moreThere are many vector-borne diseases, including dengue, that lack vaccines or effective treatment options, resulting in vector control being the primary disease control strategy. Wolbachia, an intracellular bacterium that can spread itself through a population via cytoplasmic incompatibility (CI), has been shown to inhibit the transmission of a number of the deadly human pathogens, like dengue and Plasmodium, in mosquitoes. In order to utilize Wolbachia to make mosquitoes inhospitable to the pathogens, we have to create a more efficient population replacement strategy such that disease transmission can be interrupted completely and rapidly. In this work, we performed Aedes aegypti laboratory cage studies in which the Wolbachia-infected females were released once, at the beginning, followed by continued inundative infected male release at every generation. We found that this inundative male release could accelerate the process of population replacement. We also designed a new mathematical model that is capable of accurately predicting the generation in which population replacement will occur. To develop a population replacement strategy for Aedes albopictus we introduced the third type of Wolbachia, wPip, into this mosquito species to create a transinfected line carrying a triple Wolbachia infection. We characterized the pattern of CI induced by this novel artificial infection through crossing assays. We found that the triply infected Ae. albopictus induces unidirectional CI when crossed with the wild type doubly infected mosquitoes, supporting its potential to be used in population replacement study.
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Title: Wole Soyinka's concepts of theatre : a study of A dance of the forests, the road, and Kongi's harvest
Creator: Ebong, Inih Akpan
Date: 1980
Collection: Electronic Theses & Dissertations

Title: Woman of the sound the stars make rushing through the sky : a literary biography of Jane Johnston Schoolcraft
Creator: Stone-Gordon, Tammy
Date: 1993
Collection: Electronic Theses & Dissertations

Title: Woman's channel, but man's world : how the advertising on Lifetime television perpetuates gender inequality
Creator: Kaplan, Lorraine Marie
Date: 1992
Collection: Electronic Theses & Dissertations

Title: Woman's role in the novels of Benito Perez Galdos
Creator: Soriano, Jesse Manuel
Date: 1963
Collection: Electronic Theses & Dissertations

Title: Women administrators in Big Ten universities
Creator: Stevenson, Florence Byrd, 1922-
Date: 1974
Collection: Electronic Theses & Dissertations

Title: Women advocates in Great Lakes conservation
Creator: Joseph, Sonia T.
Date: 2004
Collection: Electronic Theses & Dissertations

Title: Women and AIDS in Africa : unequal experiences, unequal representations
Creator: Swezey, Teresa Ann
Date: 1993
Collection: Electronic Theses & Dissertations

Title: Women and anger : the relationship between sex role, self-esteem and awareness, expression, and condemnation of anger
Creator: Hockett, Cynthia Anne
Date: 1988
Collection: Electronic Theses & Dissertations

Title: Women and education in Lansing, Michigan, 1904-1925
Creator: Culcasi, Tracy Elizabeth
Date: 1999
Collection: Electronic Theses & Dissertations

Title: Women and language : from deviants to strategists - views from the crossroads
Creator: Salazar, Claudia
Date: 1987
Collection: Electronic Theses & Dissertations

Title: Women and men's ideal leadership style preferences within the workplace : the influence of connectedness needs, ethnicity, age, and educational level
Creator: Boatwright, Karyn Jois
Date: 1998
Collection: Electronic Theses & Dissertations

Title: Women and militancy : narratives from Guatemala, India, and South Africa
Creator: Deb, Basuli
Date: 2007
Collection: Electronic Theses & Dissertations

Title: Women and music in the Venetian ospedali
Creator: Tonelli, Vanessa M.
Date: 2013
Collection: Electronic Theses & Dissertations
Description: The Venetian ospedali provided unique places in which women could train and perform as professional musicians. Much of our understanding of the ospedali, however, has been formed through the study of individual, male composers who wrote for the ospedali, of specific musical genres, such as motets or oratorios, or of individual archival collections. Studies of the female students and their lives are scarce. Additionally, ideas about gender shaped and continue to shape our understanding of...
Show moreThe Venetian ospedali provided unique places in which women could train and perform as professional musicians. Much of our understanding of the ospedali, however, has been formed through the study of individual, male composers who wrote for the ospedali, of specific musical genres, such as motets or oratorios, or of individual archival collections. Studies of the female students and their lives are scarce. Additionally, ideas about gender shaped and continue to shape our understanding of these all-female institutions. To address these issues, this thesis focuses on the lives and public perceptions of the ospedali musicians. Chapter One contextualizes the ospedali's organization in Venetian history and culture, addressing why Venetian society considered it acceptable for the female students to perform publically in a European society that generally frowned upon professional female musicians. Chapter Two examines contemporary commentaries and reviews (both positive and negative) about the ospedali. These descriptions are compared to contemporary ideas of femininity to show how gendered thought has influenced historical representation of the female ospedali musicians. Chapter Three focuses on the music performed and written in the ospedali, and investigates how gender typecasts influenced visitors' perceptions of the ospedali's music.
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Title: Women at work : housewives and paid workers as mothers in contemporary realistic fiction for children
Creator: Parish, Margaret Holt, 1937-
Date: 1976
Collection: Electronic Theses & Dissertations

Title: Women coping with life : a mixed methods study of incarcerated women with life sentences
Creator: Fedock, Gina
Date: 2015
Collection: Electronic Theses & Dissertations
Description: Life sentences have increasingly translated into prison stays until the end of natural life. Incarcerated women serving life sentences comprise a small, but growing, sub-population of the prison population. Women with life sentences enter prison with high rates of physical and mental health concerns, and these concerns are often chronic and recurring needs for women’s duration in prison. Pressing concerns include persistent depression and suicide risk factors. However, there is a lack of...
Show moreLife sentences have increasingly translated into prison stays until the end of natural life. Incarcerated women serving life sentences comprise a small, but growing, sub-population of the prison population. Women with life sentences enter prison with high rates of physical and mental health concerns, and these concerns are often chronic and recurring needs for women’s duration in prison. Pressing concerns include persistent depression and suicide risk factors. However, there is a lack of research focused on improving this population’s mental health, and specifically, no existing intervention for this population of women. Thus, this dissertation seeks to enhance and broaden the knowledge base about factors that influence the mental health of women with life sentence in order to provide clarity and guide advocacy for prison-based mental health services. Also, this dissertation includes a sub-study that examines the mental health outcomes for a new intervention with this population of women. Two key theories serve as the foundation for this dissertation: importation theory and deprivation theory. Three sub-studies comprise three core chapters of this dissertation. Across these studies, the results highlight implications for social work practice, policy, and research.
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