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Pages
- Title
- Development of a spice formulation for pure culture fermented cucumber pickles
- Creator
- Marshall, Cecelia Kuhnley
- Date
- 1971
- Collection
- Electronic Theses & Dissertations
- Title
- Long-time convergence of harmonic map heat flows from surfaces into Riemannian manifolds
- Creator
- Choi, Kwangho
- Date
- 2011
- Collection
- Electronic Theses & Dissertations
- Description
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We study the long-time convergence of harmonic map heat flows from a closed Riemann surface into a compact Riemannian manifold. P. Topping constructed an example of a flow that does not converge in the infinite-time limit. Motivated by the observation that Topping's flow has accumulation points at which the Hessian of the energy function is degenerate, we prove convergence under the assumptions that (a) the Hessian of the energy at an accumulation point is positive definite, and (b) no...
Show moreWe study the long-time convergence of harmonic map heat flows from a closed Riemann surface into a compact Riemannian manifold. P. Topping constructed an example of a flow that does not converge in the infinite-time limit. Motivated by the observation that Topping's flow has accumulation points at which the Hessian of the energy function is degenerate, we prove convergence under the assumptions that (a) the Hessian of the energy at an accumulation point is positive definite, and (b) no bubbling occurs at infinite time. In addition, we present examples of heat flows for geodesics which show that the convexity of the energy function and convergence at infinite time may not hold even for 1-dimensional harmonic map heat flows.
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- Title
- Relation between wind velocity and wind pressures
- Creator
- Branch, Robert M.
- Date
- 1931
- Collection
- Electronic Theses & Dissertations
- Title
- Timelessness and process-reactive schizophrenia
- Creator
- Brand, Don J.
- Date
- 1975
- Collection
- Electronic Theses & Dissertations
- Title
- Effects of an ion exchange resin artificial kidney in dogs
- Creator
- Richardson, John H.
- Date
- 1960
- Collection
- Electronic Theses & Dissertations
- Title
- Silage removal from the horizontal silo
- Creator
- Rich, Nathan Harold
- Date
- 1953
- Collection
- Electronic Theses & Dissertations
- Title
- Efficiency studies at the Highland park pumping station
- Creator
- Rieger, William Norman
- Date
- 1941
- Collection
- Electronic Theses & Dissertations
- Title
- Identifying Palestinians : Palestinian refugees and the politics of ethno-national identity in Jordan
- Creator
- Pérez, Michael Vicente
- Date
- 2011
- Collection
- Electronic Theses & Dissertations
- Description
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Based on extensive research (January 2006 - January 2008) among Palestinian refugees living within United Nations Relief and Works Agency camps in Amman, Jordan, my dissertation examines how the contingencies of local and transnational politics constitute particular forms of identification that underscore the possibilities and limits of Palestinian ethnicity and nationhood. My dissertation underscores three critical issues within the process of ethno-national identification among diaspora...
Show moreBased on extensive research (January 2006 - January 2008) among Palestinian refugees living within United Nations Relief and Works Agency camps in Amman, Jordan, my dissertation examines how the contingencies of local and transnational politics constitute particular forms of identification that underscore the possibilities and limits of Palestinian ethnicity and nationhood. My dissertation underscores three critical issues within the process of ethno-national identification among diaspora Palestinians. First, my research shows how Palestinian ethno-national identifications reflect two critical issues: (1) the exclusionary discourse and practices of Transjordanian nationalists and the Jordanian State and (2) the desire to identify as Palestinians, not Jordanians. To challenge their marginalization in Jordan, Palestinians rely on pan-Arab and religious identifications that emphasize their ethno-religious commonality with Jordanians while preserving their distinct ethno-national identification as Palestinians. Second, my research demonstrates how categories of national and religious identification among refugees indicate the intersections between local concerns and transnational politics. I show how the idioms of religious nationalism articulated by refugees concerning the homeland reflect the significance of Palestinian homeland politics in Jordanian camps and offer Palestinians an opportunity to assert national identifications in a context where Palestinian nationalism is strictly controlled. Finally, my dissertation examines how the unique experience and meaning of life as a refugee in Jordan facilitates national identifications defined in terms of displacement and exile. As I show, refugee status constitutes a central point of identification among Palestinians that enables specific forms of ethnic and national belonging grounded in the experience of prolonged displacement and the myth of return.This dissertation reflects a central concern over the impact of transnational migration and displacement upon the formation and meaning of ethno-national communities and their location within the nation-state. My work examines how ethnic and national categories, whether at the level of the state, national elites, or everyday people, are produced within the nexus of local and transnational struggles that underscore the often contentious position of migrant communities within host states and homeland politics. By recognizing that the process of identification among displaced peoples reflects transnational realities, my research highlights the instability of social categories and the conditions under which they are represented, resisted, and claimed.
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- Title
- A study of the relative length of the forcing period required by the new lily Lilium longiflorum variety downingi, as compared to the standard Easter lily varieties L. longiflorum varieties giganteum and erabu
- Creator
- Roberts, Evan P.
- Date
- 1941
- Collection
- Electronic Theses & Dissertations
- Title
- A follow-up study of former students enrolled in agriculture in Flathead county high school, Kalispell, Montana during the period 1913 to 1949
- Creator
- Robinson, Henry Edward
- Date
- 1952
- Collection
- Electronic Theses & Dissertations
- Title
- Statistical and computational methods for biological data
- Creator
- Hao, Yuning
- Date
- 2019
- Collection
- Electronic Theses & Dissertations
- Description
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The development of biological data focuses on machine learning and statistical methods. In immunotherapy, gene-expression deconvolution is used to quantify different types of cells in a mixed population. It provides a highly promising solution to rapidly characterize the tumor-infiltrating immune landscape and identify cold cancers. However, a major challenge is that gene-expression data are frequently contaminated by many outliers that decrease the estimation accuracy. Thus, it is imperative...
Show moreThe development of biological data focuses on machine learning and statistical methods. In immunotherapy, gene-expression deconvolution is used to quantify different types of cells in a mixed population. It provides a highly promising solution to rapidly characterize the tumor-infiltrating immune landscape and identify cold cancers. However, a major challenge is that gene-expression data are frequently contaminated by many outliers that decrease the estimation accuracy. Thus, it is imperative to develop a robust deconvolution method that automatically decontaminates data by reliably detecting and removing outliers. Our development of an algorithm called adaptive Least Trimmed Square (aLTS) identifies outliers in regression models, allows us to effectively detect and omit the outliers, and provides us robust estimations of the coefficients. For the guarantees of the convergence property and parameters recovery, we also included certain theoretical results.Another interesting topic is the investigation of the association of phenotype responses with the identified intricate patterns in transcription factor binding sites for DNA sequences. To address these concerns, we pushed forward with a deep learning-based framework. On one hand, to capture regulatory motifs, we utilized convolution and pooling layers. On the other hand, to understand the long-term dependencies among motifs, we used position embedding and multi-head self-attention layers. We pursued the improvement of our model's overall efficacy through the integration of transfer learning and multi-task learning. To ascertain confirmed and novel transcription factor binding motifs (TFBMs), along with their relationships internally, we provided interpretations of our DNA quantification model.
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- Title
- Variation in feed efficiency and carcass characteristics of individually fed swine
- Creator
- Vorkapich, Mike
- Date
- 1955
- Collection
- Electronic Theses & Dissertations
- Title
- Role of propionate and uncouplers of oxidative phosphorylation on hepatic metabolism and feeding behavior in dairy cows
- Creator
- Kennedy, Katherine Marie
- Date
- 2019
- Collection
- Electronic Theses & Dissertations
- Description
-
The negative energy balance of dairy cows in the postpartum period is exacerbated by a suppression in appetite. Metabolic diseases resulting from negative energy balance can decrease milk production, health and fertility, increasing risk of culling. Research suggests that feeding behavior is linked to the oxidation of fuels in the liver and that an increase in oxidation of fuels causes satiety. Propionate derived from the fermentation of starch in the rumen is a major glucose precursor in...
Show moreThe negative energy balance of dairy cows in the postpartum period is exacerbated by a suppression in appetite. Metabolic diseases resulting from negative energy balance can decrease milk production, health and fertility, increasing risk of culling. Research suggests that feeding behavior is linked to the oxidation of fuels in the liver and that an increase in oxidation of fuels causes satiety. Propionate derived from the fermentation of starch in the rumen is a major glucose precursor in dairy cows but can also cause hypophagia. Because propionate is anaplerotic, it stimulates the oxidation of fuels in the liver, likely causing the hypophagic effects. In order to determine the role of anaplerotic metabolites and uncouplers of oxidative phosphorylation on hepatic metabolism and feeding behavior in dairy cows, 6 studies were conducted. First, using 8 dairy cows in a duplicated 4x4 Latin square design, the effect of feed status (before or after access to feed) on the hepatic extraction and metabolism of propionate over 20 min was determined. The results indicated that hepatic extraction and metabolism of propionate is very rapid, and that metabolite concentrations were greater after compared with before feeding. Additionally, potential bottlenecks of propionate metabolism were identified. Secondly, a study using hepatic explants incubated in [13C3]sodium propionate was conducted to test the effects of 3 different concentrations of propionate (1, 2 or 4 mM) on propionate metabolism over 60 min. An increased concentration of propionate in the range from 1 - 4 mM resulted in the conversion of propionate to acetyl CoA, likely through pyruvate, and that the acetyl CoA was incorporated into the TCA cycle for oxidation. Additionally, metabolism of [13C3]propionate occurred rapidly with significant increases of 13C enrichment detected within 0.5 min for many metabolites. Furthermore, uncoupling the electron transport chain should affect the metabolism of propionate and the feeding behavior of dairy cows as a result of inefficient oxidation of fuels. The effects of two uncouplers of oxidative phosphorylation, 2,4-dinitrophenol methyl ether (DNPME) and sodium salicylate (SAL), on feeding behavior in dairy cows were determined in 2 experiments. Treatment with DNPME and SAL decreased eating rate in dairy cows over the first 4 h following access to feed. Additionally, DNPME increased meal length over the first 4 h following access to feed. Lastly, an experiment was conducted to determine the effects of DNPME and SAL on metabolism and oxidation of propionate over 60 min using hepatic explants from 8 dairy cows. Neither DNPME nor SAL increased oxidation. The DNPME treatment did not alter metabolism of propionate except for an increase of propionate converted to succinyl CoA, however, SAL decreased glucose synthesis from propionate. From this research, we conclude that hepatic metabolism of propionate occurs rapidly and is likely having effects on feeding behavior within minutes as well. As such, the importance of short-term metabolism in regard to feeding behavior and dry matter intake should be considered in future research. Understanding the mechanisms for metabolic control of feed intake will lead to development of novel nutritional or pharmacological approaches to increase energy intake, health, and milk yield of dairy cows; thus, improving nutrient utilization and sustainability of the dairy industry.
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- Title
- Tailoring the growth and electronic structure of organic molecular heterointerfaces
- Creator
- Tan, Andrew W. J.
- Date
- 2019
- Collection
- Electronic Theses & Dissertations
- Description
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In the rapidly developing electronics industry, it has become increasingly necessary to explore materials that are cheap, flexible and versatile which have led to significant research efforts towards organic molecular thin films. Understanding and control of heterointerface between highly ordered organic molecular thin films with extended π systems and inorganic materials are therefore of critical importance for the development of modern organic electronics. Organic molecules are unique...
Show moreIn the rapidly developing electronics industry, it has become increasingly necessary to explore materials that are cheap, flexible and versatile which have led to significant research efforts towards organic molecular thin films. Understanding and control of heterointerface between highly ordered organic molecular thin films with extended π systems and inorganic materials are therefore of critical importance for the development of modern organic electronics. Organic molecules are unique compared to their inorganic atomic counterparts as their properties can be tuned drastically through chemical functionalization, offering versatility, though their extended shape and weak intermolecular interactions bring significant challenges to the control of both the growth and the electronic structures of molecular thin films. This is further complicated by interaction between organic molecules and the underlying substrate which can lead to interfacial effects such as charge transfer, chemical interaction and electrostatic screening, all of which can significantly impact device performance and/or the characteristic of the organic thin film. This dissertation will first focus on a systematic review of the growth and electronic structure of organic molecular thin films, particularly on weakly interacting substrates. The self-assembly process and how long-range ordered organic molecular thin films are established will be discussed. We will also discuss how the electronic structures of thin films are impacted by the molecule’s local electrostatic environment and its interaction with the substrate, within the context of controlling interfacial energy level alignment between organic semiconductors and electrodes in electronic devices. Employing scanning tunneling microscopy and spectroscopy, experimental studies focusing on characterizing the growth and electronic structure of organic molecules on weakly interacting substrates were carried out and discussed. Studies focusing on the electronic structure of zinc phthalocyanine (ZnPc) and its fluorinated counterpart F16ZnPc were carried out on the deactivated Si(111)-B surface and h-BN/Cu(111). We show that interfacial charge transfer occurs between the deactivated Si(111)-B substrate and the F16ZnPc monolayer, which gives rise to a pronounced spatial variation of the occupied molecular state across the molecular assembly attributed to the inhomogeneous electrostatic screening of the intra-orbital Coulomb interaction in molecular adsorbates arising from the substrate boron distribution in the deactivated Si(111)-B substrate. To circumvent this inhomogeneous effect, the donor-acceptor molecular pair was studied on weakly interacting hexagonal boron nitride (h-BN)/Cu(111) which possesses a periodic electronic corrugation. We show that the formation of the lateral heterostructure drastically increases the charge transfer between F16ZnPc molecules and the substrate, which is attributed to the greater electrostatic stability of the heterostructure compared to that of the pure phase. This study highlights the importance of the substrate, even a weakly interacting one, such as h-BN/metal, can still perturb the intermolecular charge transfer and thereby the heterostructure behaviors via interfacial processes. The focus of a secondary study was to initiate preliminary experimentation towards understanding the substrate’s influence on the exotic properties of a class of organic-based systems known as charge transfer complexes (CTC). By utilizing the unique modulation properties of various weakly-interacting substrates, control of the properties of CTCs could be attained allowing for a better understanding of their fundamental physical mechanism to be developed and a new class of thin-film CTCs which will be highly relevant towards organic electronics to be developed.
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- Title
- The effect of growth-restriction on voluntary physical activity engagement in mice
- Creator
- Leszczynski, Eric
- Date
- 2019
- Collection
- Electronic Theses & Dissertations
- Description
-
INTRODUCTION. Current evidence suggests that early life growth restriction reduces physical activity engagement. Therefore, the purpose of this investigation was to examine the effects of early life growth-restriction on levels of wheel running in mice, and determine if known biological mechanisms regulate physical activity engagement. METHODS. Using a cross-fostering, protein-restricted nutritive model, mice were growth-restricted during either gestation (GUN; N = 3 litters) or postnatal...
Show moreINTRODUCTION. Current evidence suggests that early life growth restriction reduces physical activity engagement. Therefore, the purpose of this investigation was to examine the effects of early life growth-restriction on levels of wheel running in mice, and determine if known biological mechanisms regulate physical activity engagement. METHODS. Using a cross-fostering, protein-restricted nutritive model, mice were growth-restricted during either gestation (GUN; N = 3 litters) or postnatal life (PUN; N = 3 litters), along with a well fed control group (CON; N = 3 litters). At 21 days of age, all mice pups were weaned and fed a non-restrictive healthy diet for the remainder of the study. At 45 days of age mice were individually housed in cages with free moving running wheels to assess physical activity engagement. At day 70, mice were euthanized, and the nucleus accumbens was analyzed for dopamine receptor 1 expression. Skeletal muscle fiber type and cross-sectional area of the soleus, extensor digitorom longus, and diaphragm were analyzed by immunohistochemistry. The soleus from the other hind leg was evaluated for calsequestrin 1 and annexin A6 expression. RESULTS. The PUN female mice had a reduction (P = 0.0221) in wheel revolutions per day as compared to the GUN and CON females. PUN female mice also expressed significantly higher Drd1(P = 0.0247) and Casq1 (P = 0.0398) compared to the other groups. CONCLUSION. Growth-restriction during lactation reduced physical activity in female mice by reducing the central drive to be active and displayed a more fatigable skeletal muscle phenotype.
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- Title
- Testing a model of healthy marriage/healthy relationships : the prediction of parenting and child well-being
- Creator
- Shambleau, Krista M.
- Date
- 2010
- Collection
- Electronic Theses & Dissertations
- Description
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Federally funded Healthy Marriage Initiative (HMI) programs provide marriage education as well as other services to low-income diverse individuals and couples at many points along the marital continuum with improving children's well-being as the overarching purpose. These programs need appropriate measures of healthy marriage for couples with children that relate to well-being. Purposes of this research were to examine the factor structure of a healthy marriage measurement developed by...
Show moreFederally funded Healthy Marriage Initiative (HMI) programs provide marriage education as well as other services to low-income diverse individuals and couples at many points along the marital continuum with improving children's well-being as the overarching purpose. These programs need appropriate measures of healthy marriage for couples with children that relate to well-being. Purposes of this research were to examine the factor structure of a healthy marriage measurement developed by Manpower Demonstration Research Corporation (MDRC) and how it varied across (a) gender, (b) race (African American and Caucasian), and (c) marital status (married and unmarried). An additional purpose was to test a measurement model, developed by Child Trends, Inc., in which healthy marriage is hypothesized to predict parenting and child well-being. This cross-sectional quantitative survey research included 343 Head Start parents (151 males and 189 females) involved in a marriage/relationship. Overall, the unidimensional healthy marriage measurement fit for both males and females and the addition of two marital virtues, namely forgiveness and teamwork, also loaded well on this measurement. The factor loadings were significant for both males and females and results of chi-square difference tests indicated that the factor loadings for the great majority of variables were invariant across gender. However, the factor loading for relationship stability (one's assessment that their relationship is not in trouble) was larger for males whereas child commitment (one's assessment of their spouse/partner's commitment to their child) was larger for females. Path analysis demonstrated that the Child Trends, Inc. healthy marriage measurement model fit differed by gender and this was supported by further SEM analysis. The effect size for the direct path between risk and healthy marriage was significantly larger for females than for males. The effect size of this path tended to be greater for African American women and unmarried women. Results using fit indices showed that the fit of the measurement model was appropriate for the diverse sample. Mediation results revealed that for both males and females, healthy marriage partially mediates the effect that depression and stress have on parenting. For females, parenting partially mediates the effect between risk and children's social competence as well as between healthy marriage/healthy relationships and children's social competence. Findings demonstrate support for the Child Trends' measurement model that healthy marriage/healthy relationships may enhance children's social competence through positive parenting. Study results may inform federal and state healthy marriage and family initiatives as well as marriage and relationship education in terms of program delivery and evaluation.
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- Title
- Techniques and results of applying thiourea to synthetic and grass silage media for the control of Stomoxys calcitrans Linnaeus
- Creator
- Weinburgh, Harry B.
- Date
- 1956
- Collection
- Electronic Theses & Dissertations
- Title
- A survey study of the metazoan fauna of the psammolittoral zone of Mud Lake, Barry County, Michigan
- Creator
- Weber, Peter Gotthilf
- Date
- 1963
- Collection
- Electronic Theses & Dissertations
- Title
- River valley lands in Southwestern Ontario
- Creator
- Weber, Edward J.
- Date
- 1966
- Collection
- Electronic Theses & Dissertations
- Title
- A study of the development and awareness of the need for creative uses of leisure time of high school students in a working class community
- Creator
- Welch, Gordon R.
- Date
- 1967
- Collection
- Electronic Theses & Dissertations