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(29,261 - 29,280 of 29,417)
Pages
- Title
- Wittgenstein's new kind of foundationalism
- Creator
- Brice, Robert G.
- Date
- 2004
- Collection
- Electronic Theses & Dissertations
- Title
- Wolbachia induces resistance to dengue virus in mosquito Aedes aegypti
- Creator
- Lu, Peng (Of Michigan State University)
- Date
- 2014
- Collection
- Electronic Theses & Dissertations
- Description
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Transmitted by the bite of mosquitoes, dengue virus (DENV) is the most important arboviral pathogen in humans. Currently no drug therapy or vaccine is available for dengue fever, leaving vector control as the major way to protect human populations. The endosymbiotic bacterium Wolbachia has been proposed as a potential agent for vector control, because it can not only spread within mosquito populations via manipulation of mosquito reproduction but also inhibit transmission of DENV in...
Show moreTransmitted by the bite of mosquitoes, dengue virus (DENV) is the most important arboviral pathogen in humans. Currently no drug therapy or vaccine is available for dengue fever, leaving vector control as the major way to protect human populations. The endosymbiotic bacterium Wolbachia has been proposed as a potential agent for vector control, because it can not only spread within mosquito populations via manipulation of mosquito reproduction but also inhibit transmission of DENV in mosquitoes. In order to develop Wolbachia-based control strategies to prevent DENV infection, we have to better understand the interactions between DENV and Wolbachia in mosquitoes. Aedes albopictus naturally carries Wolbachia infection, however, Wolbachia-mediated viral resistance was not observed in Ae. albopictus. In this study, we demonstrated that the native Wolbachia induce a resistance to DENV in Wolbachia density-dependent manner in Ae. albopictus. A decrease in Wolbachia density within the host cells results in increased dengue infection. We provide evidence that a very low Wolbachia density in mosquito tissues where DENV resides and travels could contribute to the absence of Wolbachia-mediated resistance to DENV in Ae. albopictus. We also investigated the impact of Wolbachia infection on DENV life cycle. We report here that Wolbachia is able to inhibit the intracellular accumulation of DENV in Aedes. aegypti mosquito cells. We showed that Wolbachia infection inhibits DENV binding to mosquito Aag2 cells. We then compared the DENV negative strand RNA levels in Wolbachia infected and uninfected mosquito cells. Wolbachia infection also inhibits DENV replication in mosquito Aag2 cells.To further investigate Wolbachia-DENV interactions in mosquito, we carried out microarray and real-time PCR analyses to define host cell transcriptional responses that are induced by Wolbachia infection. Our data indicates that sixteen previously identified DENV host factors were up-regulated in mosquito cells infected with Wolbachia. An RNA interference (RNAi) screen revealed eleven host factors that are associated with Wolbachia-mediated viral resistance. Our data provides several potential targets for interrupting dengue virus infection in mosquitoes.
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- Title
- Women administrators in Big Ten universities
- Creator
- Stevenson, Florence Byrd, 1922-
- Date
- 1974
- Collection
- Electronic Theses & Dissertations
- Title
- Women and anger : the relationship between sex role, self-esteem and awareness, expression, and condemnation of anger
- Creator
- Hockett, Cynthia Anne
- Date
- 1988
- Collection
- Electronic Theses & Dissertations
- Title
- Women and men's ideal leadership style preferences within the workplace : the influence of connectedness needs, ethnicity, age, and educational level
- Creator
- Boatwright, Karyn Jois
- Date
- 1998
- Collection
- Electronic Theses & Dissertations
- Title
- Women and militancy : narratives from Guatemala, India, and South Africa
- Creator
- Deb, Basuli
- Date
- 2007
- Collection
- Electronic Theses & Dissertations
- Title
- Women at work : housewives and paid workers as mothers in contemporary realistic fiction for children
- Creator
- Parish, Margaret Holt, 1937-
- Date
- 1976
- Collection
- Electronic Theses & Dissertations
- Title
- Women coping with life : a mixed methods study of incarcerated women with life sentences
- Creator
- Fedock, Gina
- Date
- 2015
- Collection
- Electronic Theses & Dissertations
- Description
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Life sentences have increasingly translated into prison stays until the end of natural life. Incarcerated women serving life sentences comprise a small, but growing, sub-population of the prison population. Women with life sentences enter prison with high rates of physical and mental health concerns, and these concerns are often chronic and recurring needs for women’s duration in prison. Pressing concerns include persistent depression and suicide risk factors. However, there is a lack of...
Show moreLife sentences have increasingly translated into prison stays until the end of natural life. Incarcerated women serving life sentences comprise a small, but growing, sub-population of the prison population. Women with life sentences enter prison with high rates of physical and mental health concerns, and these concerns are often chronic and recurring needs for women’s duration in prison. Pressing concerns include persistent depression and suicide risk factors. However, there is a lack of research focused on improving this population’s mental health, and specifically, no existing intervention for this population of women. Thus, this dissertation seeks to enhance and broaden the knowledge base about factors that influence the mental health of women with life sentence in order to provide clarity and guide advocacy for prison-based mental health services. Also, this dissertation includes a sub-study that examines the mental health outcomes for a new intervention with this population of women. Two key theories serve as the foundation for this dissertation: importation theory and deprivation theory. Three sub-studies comprise three core chapters of this dissertation. Across these studies, the results highlight implications for social work practice, policy, and research.
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- Title
- Women high school principals : moving beyond the myth
- Creator
- Pecora, Kathleen Emily
- Date
- 2006
- Collection
- Electronic Theses & Dissertations
- Title
- Women in athletic training, their career and educational experiences
- Creator
- Shingles, René R.
- Date
- 2001
- Collection
- Electronic Theses & Dissertations
- Title
- Women in the ministry personality and background characteristics of a group of United Methodist clergy and theological students
- Creator
- Orrick, Martha
- Date
- 1984
- Collection
- Electronic Theses & Dissertations
- Title
- Women of Iqbal Street : popular models of health and illness
- Creator
- Eickmeier, Janice Louise
- Date
- 1989
- Collection
- Electronic Theses & Dissertations
- Title
- Women of advanced maternal age and miscarriage : an examination of the essence of the experience
- Creator
- Wright, Rebecca Jean
- Date
- 2013
- Collection
- Electronic Theses & Dissertations
- Description
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"This qualitative study explores the essence of the experience of miscarriage among women aged 35 years and older. ... The salient themes identified suggest that women experience miscarriage from a physical, emotional, temporal and social context. From these themes of experience , the essence of miscarriage for the participants in this study were found to be 1) physically experiencing intense loss and grief, 2) having a sense of otherness, 3) a continuous search for meaning and 4) feelings of...
Show more"This qualitative study explores the essence of the experience of miscarriage among women aged 35 years and older. ... The salient themes identified suggest that women experience miscarriage from a physical, emotional, temporal and social context. From these themes of experience , the essence of miscarriage for the participants in this study were found to be 1) physically experiencing intense loss and grief, 2) having a sense of otherness, 3) a continuous search for meaning and 4) feelings of regret and self-blame."--From abstract.
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- Title
- Women of color faculty in STEM : successfully navigating the promotion and tenure process
- Creator
- Soto, Melissa
- Date
- 2014
- Collection
- Electronic Theses & Dissertations
- Description
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Black women and Hispanic/Latina faculty are underrepresented in tenured science, technology, engineering, and mathematics (STEM) positions at research universities. Despite this fact, this demographic group is increasingly recognized at the national level as a key source of underutilized talent that may significantly contribute to the nations' STEM talent pool. As a result, resources continue to be allocated to higher education institutions to support the successful career advancement of...
Show moreBlack women and Hispanic/Latina faculty are underrepresented in tenured science, technology, engineering, and mathematics (STEM) positions at research universities. Despite this fact, this demographic group is increasingly recognized at the national level as a key source of underutilized talent that may significantly contribute to the nations' STEM talent pool. As a result, resources continue to be allocated to higher education institutions to support the successful career advancement of women of color in STEM. Yet, little empirical data currently exists about how these faculty members successfully navigate the promotion and tenure process based on the salient challenges they face as probationary faculty. The purpose of this study is to investigate the factors that contribute to the successful career advancement of tenured Black women and Hispanic/Latina STEM faculty fromassistant to associate professors at predominately White, research institutions. A sub-focus of this study is to identify the challenges faced by the participants during their early career. This qualitative study is guided by social cognitive theory and the literature on faculty development. A purposeful snowball sampling technique (n=13) is utilized. Respondents filled out an online demographic questionnaire and participated in one round of telephone interviews (90-120 minutes). The findings show that the participants faced five key challenges as probationary, early career faculty. Seven personal and external strategies enabled the participants to mitigate these challenges and contributed to their successful promotion and tenure. Suggestions for future research and implications for policy and practice are presented.
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- Title
- Women of color international graduate students' perceptions and experiences of safety and violence while studying in the United States
- Creator
- Naik, Sapna
- Date
- 2021
- Collection
- Electronic Theses & Dissertations
- Description
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The purpose of this dissertation was to understand women of color international graduate students’ conceptualizations, perceptions, and experiences of violence and safety, in addition to the influences of those perceptions and experiences on their lives, while studying in the United States. I perceived women of color international graduate students to be at a particular juncture of political context and oppressions that could influence their experiences. I conducted a qualitative interview...
Show moreThe purpose of this dissertation was to understand women of color international graduate students’ conceptualizations, perceptions, and experiences of violence and safety, in addition to the influences of those perceptions and experiences on their lives, while studying in the United States. I perceived women of color international graduate students to be at a particular juncture of political context and oppressions that could influence their experiences. I conducted a qualitative interview study of 11 women of color international graduate students enrolled in doctoral programs at two universities in the southern United States. I was informed by a framework made up of intersectionality and transnational feminism. I learned women of color international graduate students’ conceptualizations of violence and safety complicated those found in the literature by understanding violence and safety in terms of physical, non-physical, and security aspects. Participants also had complex experiences and perceptions, including experiences of sexual harassment, threats of physical violence, discrimination, and silencing. Participants shared financial and visa status insecurity as contributing to lack of safety. I found policies and events factored into participants’ assessments of safety to varying degrees, with gun violence and campus carry factoring in heavily while sexual harassment from faculty members was less of a concern. Coronavirus emerged as contributing to lack of safety. Influences on participants’ lives included the creation of strategies to maintain safety and prevent violence. In addition, I found participants spent a lot of time and energy thinking about their safety. Participants had perspectives about effects on their own lives including loss of freedom and increased empowerment. I asked participants about their perspectives of university responsibility. While some participants did not perceive the university had additional responsibility than what was already done, others perceived their universities could improve on transparency and training. Their recommendations informed my recommendations in the final chapter. I offered implications for practice and policy, including universities making changes within and advocating for changes at a state and national level. I also discuss implications for theory, including the need for a racialized, gendered, internationalized, and graduate student worker lens, and one that incorporates women of color international graduate students’ previous and current locations. Suggestions for future research include research with other populations and taking into account changing contexts. I offer implications for methods including those that may help researchers studying precarious populations. My hope is this research will positively influence women of color international graduate students’ experiences in the United States.
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- Title
- Women survivors : transitions away from abusive relationships
- Creator
- Perelli, Natalie Brohl
- Date
- 2004
- Collection
- Electronic Theses & Dissertations
- Title
- Women workers in India's pharmaceutical industry : a study of industry structure and social stratification
- Creator
- Damle, Ranjana V.
- Date
- 1992
- Collection
- Electronic Theses & Dissertations
- Title
- Women writing men : genre, narrative authority, and "mind writing" 1752-1817
- Creator
- Kane, Jessica
- Date
- 2019
- Collection
- Electronic Theses & Dissertations
- Description
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"I argue that women writers of the long eighteenth century used readers' expectations about genre to reimagine their forms through expanding the socially- and narratively-limited roles of female characters. My chapters demonstrate how the female protagonists in four different texts---Charlotte Lennox's Female Quixote, Frances Burney's Evelina, Elizabeth Inchbald's Animal Magnetism, and Jane Austen's Persuasion---take on the attributes of a narrator and author by creating both their male love...
Show more"I argue that women writers of the long eighteenth century used readers' expectations about genre to reimagine their forms through expanding the socially- and narratively-limited roles of female characters. My chapters demonstrate how the female protagonists in four different texts---Charlotte Lennox's Female Quixote, Frances Burney's Evelina, Elizabeth Inchbald's Animal Magnetism, and Jane Austen's Persuasion---take on the attributes of a narrator and author by creating both their male love interests and their stories through what I call "mind writing." "Mind writing" takes the "mind reading" of cognitive literary studies back to textuality, exploring the ways that one character asserts the thoughts, feelings, actions, or intentions of another in ways analogous to a narrator. "Mind writing" another character in these texts allows the protagonist to control where the story is going and what it is doing, ultimately allowing her to parallel the work of an author. The effect is both social and narratological, as these women characters transcend the usual definitions and limitations of both "woman" and "character." Since all four of my texts work within established genre logics and patterns, breaking these expectations via "mind writing" also means that readers must re-evaluate their own positions in relation to the text. Readers of genre fiction believe they know what they are getting when they pick up a text within that field, whether in the eighteenth century or today. By flipping the script on their readers Lennox, Burney, Inchbald, and Austen rewrite their audiences just as their female characters rewrite their stories. And because generic conventions often put the reader in a position of power, either because they can pass judgement on the characters or because they know something the characters do not, refashioning the genres puts readers in a subordinate position, re-evaluating our assumptions about the stories, ourselves, and the world on which the story comments."--Pages ii-iii.
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- Title
- Women's addresses : epistolary strategies in antebellum American literature
- Creator
- Dawson, Jennifer R.
- Date
- 2002
- Collection
- Electronic Theses & Dissertations
- Title
- Women's experiences with abortion within the context of family in Chile : a qualitative study
- Creator
- Campbell, Shannon J.
- Date
- 2009
- Collection
- Electronic Theses & Dissertations